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Eine Kombination von KVT und Antidepressiva wird jedoch aufgrund potenziell ung\u00fcnstiger Interferenzeffekte diskutiert. Untersucht wurden die Assoziationen einer bestehenden antidepressiven Medikation mit Panik- und agoraphobischer Symptombelastung und deren Ver\u00e4nderung im Kontext einer strukturierten f\u00fcnfw\u00f6chigen tagesklinischen und auf Expositionen fokussierten Behandlung in einem naturalistischen Setting.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methodik<\/jats:title>\n                <jats:p>Von insgesamt <jats:italic>n<\/jats:italic>\u202f=\u2009488 Patient*innen konnte f\u00fcr <jats:italic>n<\/jats:italic>\u202f=\u2009380 retrospektiv die Medikamenteneinnahme w\u00e4hrend der Behandlung ermittelt werden: <jats:italic>n<\/jats:italic>\u202f=\u2009100 (26,3\u202f%) nahmen Antidepressiva verschiedener Wirkstoffklassen ein. Die Berechnungen erfolgten mittels multipler linearer Regressionsanalyse, t\u2011Tests, Responseanalysen und \u03c7<jats:sup>2<\/jats:sup>-Tests.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Patient*innen mit bestehender antidepressiver Medikation erf\u00fcllten h\u00e4ufiger die Kriterien einer komorbiden depressiven St\u00f6rung (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090,001). Das Ma\u00df der Symptomver\u00e4nderung und die Therapieresponseraten unterschieden sich nicht zwischen Patient*innen mit und ohne Antidepressiva in Bezug auf die Angstsymptomatik.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion<\/jats:title>\n                <jats:p>Im untersuchten Kontext profitierten Patient*innen mit und ohne bestehende antidepressive Medikation in gleichem Ma\u00dfe von KVT in Bezug auf die Angstsymptomatik.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00115-023-01535-y","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T23:02:20Z","timestamp":1693263740000},"page":"842-848","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Expositionstherapie bei Panikst\u00f6rung und Agoraphobie im Kontext bestehender antidepressiver Medikation","Exposure therapy for panic disorder and agoraphobia in the context of existing antidepressive medication"],"prefix":"10.1007","volume":"94","author":[{"given":"Malte","family":"Hahnfeld","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Ritter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathrin","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Weidner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Noack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,8,29]]},"reference":[{"issue":"3","key":"1535_CR1","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1159\/000030642","volume":"8","author":"J Angenendt","year":"1998","unstructured":"Angenendt\u00a0J, Frommberger\u00a0U, Berger\u00a0M (1998) Zum Stellenwert psychotherapeutisch-pharmakologischer Kombinationstherapien bei Angstst\u00f6rungen. 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Das Ethikvotum erfolgte durch die Ethikkommission der Technischen Universit\u00e4t Dresden (EK 494122016). Von allen beteiligten Patient\/-innen liegt eine Einverst\u00e4ndniserkl\u00e4rung vor.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}