{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T15:04:34Z","timestamp":1774883074640,"version":"3.50.1"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T00:00:00Z","timestamp":1704326400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsmedizin Greifswald"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nervenarzt"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Einleitung\/Hintergrund<\/jats:title>\n                <jats:p>DC_TRAIN_APHASIA ist eine multizentrische, randomisiert-kontrollierte Studie, die seit November 2019 unter Federf\u00fchrung der Universit\u00e4tsmedizin Greifswald durchgef\u00fchrt wird (ClinicalTrials.gov Identifier: NCT03930121). Die Studie untersucht, ob adjuvante transkranielle Gleichstromstimulation (\u201etranscranial direct current stimulation\u201c, tDCS) den Erfolg einer 3\u2011w\u00f6chigen intensiven Sprachtherapie bei chronischer Aphasie steigern kann.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methode<\/jats:title>\n                <jats:p>Bis Ende 2024 sollen bundesweit 130 Patient:innen eingeschlossen werden. Die Entwicklung innovativer Rekrutierungsstrategien stellt seit Beginn der Studie eine Herausforderung dar. Neben g\u00e4ngigen Rekrutierungsmethoden wie der direkten Ansprache von Menschen mit Aphasie in Kliniken, Logop\u00e4diepraxen, Rehabilitationseinrichtungen und Selbsthilfegruppen wurden Radiowerbespots, Fernsehbeitr\u00e4ge und Auftritte in sozialen Medien erprobt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Zwischenergebnisse<\/jats:title>\n                <jats:p>Bis zum aktuellen Zeitpunkt konnten 110 Patient:innen in die Studie eingeschlossen werden. Zum gr\u00f6\u00dften kurzzeitigen R\u00fccklauf f\u00fchrte die Rekrutierung \u00fcber einen Fernseh- bzw. Radiobeitrag. Den gr\u00f6\u00dften langfristigen R\u00fccklauf ergab die Rekrutierung \u00fcber Logop\u00e4die- und Neurologiepraxen, Selbsthilfegruppen und soziale Medien. Teilnehmer:innen berichteten als \u201eTestimonials\u201c positiv von der Sprachtherapie und der Anwendung von tDCS, die sich als gut vertr\u00e4glich erwies.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Diskussion<\/jats:title>\n                <jats:p>Die multizentrische Studie DC_TRAIN_APHASIA pr\u00fcft die Wirksamkeit von tDCS als adjuvante Applikation f\u00fcr intensive Sprachtherapie bei chronischer Aphasie. Die vorliegende \u00dcbersicht soll k\u00fcnftigen Studien als Leitfaden zur Rekrutierung von Stichproben dienen, die Menschen mit eingeschr\u00e4nkten kommunikativen F\u00e4higkeiten umfassen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00115-023-01572-7","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T10:02:37Z","timestamp":1704362557000},"page":"368-375","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Transkranielle Gleichstromstimulation zur Verbesserung der Trainingseffektivit\u00e4t bei chronischer Aphasie nach Schlaganfall\u00a0\u2013 wie gelingt die Studienrekrutierung Betroffener?","Transcranial direct current stimulation to enhance training effectiveness in chronic poststroke aphasia\u2014A\u00a0challenge for recruiting participants"],"prefix":"10.1007","volume":"95","author":[{"given":"Nina","family":"Unger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Stahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Darkow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronika","family":"Scholz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Weinmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Breitenstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Meinzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"Grewe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnes","family":"Fl\u00f6el","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,1,4]]},"reference":[{"key":"1572_CR1","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1016\/j.clinph.2017.06.001","volume":"128","author":"A Antal","year":"2017","unstructured":"Antal\u00a0A et\u00a0al (2017) Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines. 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