{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:35:03Z","timestamp":1779928503298,"version":"3.53.1"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsmedizin Greifswald"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Nervenarzt"],"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n              <jats:title>Hintergrund<\/jats:title>\n              <jats:p>Langzeitbetrachtungen der Alkoholabh\u00e4ngigkeit k\u00f6nnen Aufschluss zu \u00c4tiologie, Pr\u00e4vention und therapeutischer Versorgung bieten.<\/jats:p>\n            <\/jats:sec><jats:sec>\n              <jats:title>Ziel<\/jats:title>\n              <jats:p>Beschreibung empirischer Befunde zur Entwicklung in eine Alkoholabh\u00e4ngigkeit hinein und Entwicklungen aus ihr heraus.<\/jats:p>\n            <\/jats:sec><jats:sec>\n              <jats:title>Methodik<\/jats:title>\n              <jats:p>Narrative Literaturrecherche, Analyse von Ergebnissen aus Kohortenstudien in der Bev\u00f6lkerung.<\/jats:p>\n            <\/jats:sec><jats:sec>\n              <jats:title>Ergebnisse<\/jats:title>\n              <jats:p>Risikofaktoren lassen eine erh\u00f6hte Wahrscheinlichkeit der Ausbildung einer Alkoholabh\u00e4ngigkeit sch\u00e4tzen. Jugendliche zeigten innerhalb von 8\u00a0Jahren nach Beginn des Alkoholkonsums Symptome einer Alkoholabh\u00e4ngigkeit. Besteht diese, ist mit einer um 17,6 Jahre verk\u00fcrzten Lebensdauer zu rechnen. Daten einer Bev\u00f6lkerungsstichprobe zeigten gegen\u00fcber Menschen ohne psychische St\u00f6rung ein 2,8fach erh\u00f6htes Risiko, vorzeitig zu versterben. Die Schwere der Alkoholabh\u00e4ngigkeit erwies sich als Pr\u00e4diktor vorzeitigen Versterbens. Nikotinabh\u00e4ngigkeit kann neben der Alkoholabh\u00e4ngigkeit zur verk\u00fcrzten Lebensdauer beitragen. In einer Bev\u00f6lkerungsstichprobe hatten 90,2\u202f% der alkoholabh\u00e4ngigen Personen an keiner qualifizierten Entzugsbehandlung und 78,4\u202f% an keiner Entzugsbehandlung in einer psychiatrischen Einrichtung teilgenommen. Remissionen ohne suchtspezifische Hilfe sind nachgewiesen und stellen den \u00fcberwiegenden Remissionsweg dar.<\/jats:p>\n            <\/jats:sec><jats:sec>\n              <jats:title>Diskussion<\/jats:title>\n              <jats:p>Zur Reduktion der ung\u00fcnstigen langfristigen Verl\u00e4ufe sollten Pr\u00e4vention und Suchtkrankenversorgung mehr als bisher auf den Bedarf in der Bev\u00f6lkerung ausgerichtet werden. In der psychiatrischen und weiteren medizinischen Praxis sollten leitliniengem\u00e4\u00df Screenings auf Alkoholgebrauchsst\u00f6rungen und entsprechende Kurzinterventionen durchgef\u00fchrt werden.<\/jats:p>\n            <\/jats:sec>","DOI":"10.1007\/s00115-024-01719-0","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T15:30:49Z","timestamp":1724340649000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Langzeitverl\u00e4ufe der Alkoholabh\u00e4ngigkeit","Long-term courses of alcohol dependence"],"prefix":"10.1007","author":[{"given":"Ulrich","family":"John","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-J\u00fcrgen","family":"Rumpf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk","family":"Kiefer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"1719_CR1","doi-asserted-by":"publisher","first-page":"e12864","DOI":"10.1111\/gbb.12864","volume":"22","author":"A Agrawal","year":"2023","unstructured":"Agrawal\u00a0A, Brislin\u00a0SJ, Bucholz\u00a0KK et\u00a0al (2023) The Collaborative Study on the Genetics of Alcoholism: Overview. 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