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Nach der Legalisierung nichtmedizinischen Cannabis in Nordamerika und der damit einhergehenden Zunahme des Cannabiskonsums, einschlie\u00dflich hochpotenter Sorten steigt dort die Zahl der Patienten mit cannabisbezogenem zyklischem Erbrechen. Die  ROME-IV-Kriterien der Rome Foundation definieren das cannabisinduzierte zyklische Erbrechen inzwischen als Cannabinoid-Hyperemesis-Syndrom (CHS). Dieses Review m\u00f6chte \u00fcber das CHS informieren, da auch in Deutschland nach der Legalisierung mit einer Zunahme der F\u00e4lle zu rechnen ist.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methode<\/jats:title>\n                    <jats:p>Selektive \u00dcbersichtsarbeit.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ergebnisse<\/jats:title>\n                    <jats:p>Das CHS wird am h\u00e4ufigsten in den Notaufnahmen registriert. Eine eindeutige Differenzierung von CHS und Cyclic-vomiting-Syndrom (CVS), bei dem ein Drittel der Betroffenen ebenfalls regelm\u00e4\u00dfig Cannabis konsumiert, ist nur durch Feststellung einer Vollremission w\u00e4hrend einer 6\u2011 bis 12-monatigen Cannabisabstinenz m\u00f6glich. Daher werden in den Notaufnahmen zun\u00e4chst Mischformen aus CVS und CHS gesehen (suspektes CHS), auch mit versteckten vital bedrohlichen abdominellen Komorbidit\u00e4ten. Das schwere Erbrechen kann ebenfalls zu gravierenden Komplikationen f\u00fchren. \u00dcbliche Antiemetika helfen oft nicht. Hei\u00dfes Duschen und Baden sowie Haloperidol i.m. (5\u202fmg) k\u00f6nnen das schwere Erbrechen akut linderen. Auch eine Einreibung des Abdomens mit 0,1\u202f%iger Capsaicincreme wirkt antiemetisch, jedoch weniger schnell.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Diskussion<\/jats:title>\n                    <jats:p>In ROME-IV gilt das CHS nosologisch als spezielle Variante des CVS. Es ist insbesondere eine spezifische cannabisbezogene oft schwere k\u00f6rperliche Erkrankung. Da Heilung nur durch eine anhaltende Cannabisabstinenz zu erreichen ist, ist das suspekte CHS in den Notaufnahmen eine interdisziplin\u00e4re Herausforderung f\u00fcr die Gastroenterologie, Neuropsychiatrie und das Suchthilfesystem.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00115-025-01864-0","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T06:21:46Z","timestamp":1753078906000},"page":"377-381","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Das Cannabinoid-Hyperemesis-Syndrom\u00a0\u2013 ein narratives Review","The cannabinoid hyperemesis syndrome\u2014A narrative review"],"prefix":"10.1007","volume":"97","author":[{"given":"Udo","family":"Bonnet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,21]]},"reference":[{"issue":"10","key":"1864_CR1","doi-asserted-by":"publisher","first-page":"4285","DOI":"10.1096\/fj.15-272526","volume":"29","author":"KM Alawi","year":"2015","unstructured":"Alawi\u00a0KM et\u00a0al (2015) The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature. 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