{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T10:25:10Z","timestamp":1750674310151},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T00:00:00Z","timestamp":1560211200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T00:00:00Z","timestamp":1560211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiologe"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s00117-019-0558-x","type":"journal-article","created":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T14:57:45Z","timestamp":1560265065000},"page":"742-749","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Biochemische Knorpeldiagnostik \u2013 Update 2019"],"prefix":"10.1007","volume":"59","author":[{"given":"S.","family":"Trattnig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Raudner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schreiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Roemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Bohndorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,6,11]]},"reference":[{"key":"558_CR1","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1002\/mrm.1910360504","volume":"36","author":"A Bashir","year":"1996","unstructured":"Bashir A, Gray ML, Burstein D (1996) Gd-DTPA(2-) as a\u00a0measure of cartilage degradation. Magn Reson Med 36:665\u2013673","journal-title":"Magn Reson Med"},{"key":"558_CR2","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1148\/radiology.205.2.9356644","volume":"205","author":"A Bashir","year":"1997","unstructured":"Bashir A, Gray ML, Boutin RD, Burstein D (1997) Glycosaminoglycan in articular cartilage: In vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging. Radiology 205:551\u2013558","journal-title":"Radiology"},{"key":"558_CR3","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1002\/art.23459","volume":"58","author":"H Owman","year":"2008","unstructured":"Owman H, Tiderius CJ, Neuman P, Nyquist F, Dahlberg LE (2008) Association between findings on delayed gadolinium-enhanced magnetic resonance imaging of cartilage and future knee osteoarthritis. Arthritis Rheum 58:1727\u20131730","journal-title":"Arthritis Rheum."},{"key":"558_CR4","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1016\/j.joca.2014.02.929","volume":"22","author":"H Owman","year":"2014","unstructured":"Owman H, Ericsson YB, Englund M et al (2014) Association between delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and joint space narrowing and osteophytes: a\u00a0cohort study in patients with partial meniscectomy with 11 years of follow-up. Osteoarthr Cartil 22:1537\u20131541","journal-title":"Osteoarthr Cartil"},{"key":"558_CR5","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.joca.2013.02.383","volume":"21","author":"MD Crema","year":"2013","unstructured":"Crema MD, Hunter DJ, Burstein D et al (2013) The relationship between the Kellgren-lawrence grade of radiographic knee osteoarthritis and delayed gadolinium-enhanced Mri of medial Tibiofemoral cartilage (Dgemric): a 1\u2011year follow-up study. Osteoarthr Cartil 21:179\u2013S80","journal-title":"Osteoarthr Cartil"},{"key":"558_CR6","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1002\/art.38518","volume":"66","author":"MD Crema","year":"2014","unstructured":"Crema MD, Hunter DJ, Burstein D et al (2014) Delayed gadolinium-enhanced magnetic resonance imaging of medial Tibiofemoral cartilage and its relationship with meniscal pathology A longitudinal study using 3.0T magnetic resonance imaging. Arthritis Rheumatol 66:1517\u20131524","journal-title":"Arthritis Rheumatol"},{"key":"558_CR7","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1016\/j.joca.2014.04.021","volume":"22","author":"H Owman","year":"2014","unstructured":"Owman H, Tiderius CJ, Ericsson YB, Dahlberg LE (2014) Long-term effect of removal of knee joint loading on cartilage quality evaluated by delayed gadolinium-enhanced magnetic resonance imaging of cartilage. Osteoarthr Cartil 22:928\u2013932","journal-title":"Osteoarthr Cartil"},{"key":"558_CR8","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1136\/ard.2010.144725","volume":"71","author":"A Anandacoomarasamy","year":"2012","unstructured":"Anandacoomarasamy A, Leibman S, Smith G et al (2012) Weight loss in obese people has structure-modifying effects on medial but not on lateral knee articular cartilage. Ann Rheum Dis 71:26\u201332","journal-title":"Ann Rheum Dis"},{"key":"558_CR9","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1016\/j.joca.2010.01.009","volume":"18","author":"BC Fleming","year":"2010","unstructured":"Fleming BC, Oksendahl HL, Mehan WA et al (2010) Delayed gadolinium-enhanced MR imaging of cartilage (dGEMRIC) following ACL injury. Osteoarthr Cartil 18:662\u2013667","journal-title":"Osteoarthr Cartil"},{"key":"558_CR10","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1002\/mrm.10054","volume":"47","author":"EM Shapiro","year":"2002","unstructured":"Shapiro EM, Borthakur A, Gougoutas A, Reddy R (2002) Na-23 MRI accurately measures fixed charge density in articular cartilage. Magn Reson Med 47:284\u2013291","journal-title":"Magn Reson Med"},{"key":"558_CR11","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1053\/joca.1999.0303","volume":"8","author":"A Borthakur","year":"2000","unstructured":"Borthakur A, Shapiro EM, Beers J, Kudchodkar S, Kneeland JB, Reddy R (2000) Sensitivity of MRI to proteoglycan depletion in cartilage: comparison of sodium and proton MRI. Osteoarthr Cartil 8:288\u2013293","journal-title":"Osteoarthr Cartil"},{"key":"558_CR12","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1148\/radiol.2313030521","volume":"231","author":"AJ Wheaton","year":"2004","unstructured":"Wheaton AJ, Borthakur A, Shapiro EM et\u00a0al (2004) Proteoglycan loss in human knee cartilage: Quantitation with sodium MR imaging\u2014Feasibility study. Radiology 231:900\u2013905","journal-title":"Radiology"},{"key":"558_CR13","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1002\/jmri.21881","volume":"30","author":"LG Wang","year":"2009","unstructured":"Wang LG, Wu Y, Chang G et al (2009) Rapid isotropic 3D-sodium MRI of the knee joint in vivo at 7T. J\u00a0Magn Reson Imaging 30:606\u2013614","journal-title":"J Magn Reson Imaging"},{"key":"558_CR14","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1002\/mrm.23307","volume":"68","author":"G Madelin","year":"2012","unstructured":"Madelin G, Babb JS, Xia D, Chang G, Jerschow A, Regatte RR (2012) Reproducibility and repeatability of quantitative sodium magnetic resonance imaging in vivo in articular cartilage at 3\u202fT and 7\u202fT. Magn Reson Med 68:841\u2013849","journal-title":"Magn Reson Med"},{"key":"558_CR15","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1007\/s00330-017-4956-z","volume":"28","author":"G Madelin","year":"2018","unstructured":"Madelin G, Xia D, Brown R et al (2018) Longitudinal study of sodium MRI of articular cartilage in patients with knee osteoarthritis: initial experience with 16-month follow-up. Eur Radiol 28:133\u2013142","journal-title":"Eur Radiol"},{"key":"558_CR16","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1148\/radiol.10100279","volume":"257","author":"S Trattnig","year":"2010","unstructured":"Trattnig S, Welsch GH, Juras V et al (2010) Na-23 MR imaging at 7\u202fT after knee matrix-associated Autologous Chondrocyte transplantation: preliminary results. Radiology 257:175\u2013184","journal-title":"Radiology"},{"key":"558_CR17","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1016\/j.joca.2012.04.020","volume":"20","author":"S Zbyn","year":"2012","unstructured":"Zbyn S, Stelzeneder D, Welsch GH et al (2012) Evaluation of native hyaline cartilage and repair tissue after two cartilage repair surgery techniques with Na-23 MR imaging at 7\u202fT: initial experience. Osteoarthr Cartil 20:837\u2013845","journal-title":"Osteoarthr Cartil"},{"key":"558_CR18","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1097\/RLI.0000000000000117","volume":"50","author":"S Zbyn","year":"2015","unstructured":"Zbyn S, Brix MO, Juras V et\u00a0al (2015) Sodium magnetic resonance imaging of ankle joint in cadaver specimens, volunteers, and patients after different cartilage repair techniques at 7\u202fT initial results. Invest Radiol 50:246\u2013254","journal-title":"Invest Radiol"},{"key":"558_CR19","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.joca.2012.01.020","volume":"20","author":"I Krusche-Mandl","year":"2012","unstructured":"Krusche-Mandl I, Schmitt B, Zak L et al (2012) Long-term results 8 years after autologous osteochondral transplantation: 7\u202fT gagCEST and sodium magnetic resonance imaging with morphological and clinical correlation. Osteoarthr Cartil 20:357\u2013363","journal-title":"Osteoarthr Cartil"},{"key":"558_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/srep01707","author":"JS Lee","year":"2013","unstructured":"Lee JS, Parasoglou P, Xia D, Jerschow A, Regatte RR (2013) Uniform magnetization transfer in chemical exchange saturation transfer magnetic resonance imaging. Sci Rep 3. \n                    https:\/\/doi.org\/10.1038\/srep01707","journal-title":"Sci Rep"},{"key":"558_CR21","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1002\/mrm.27367","volume":"81","author":"J Windschuh","year":"2019","unstructured":"Windschuh J, Zaiss M, Ehses P, Lee JS, Jerschow A, Regatte RR (2019) Assessment of frequency drift on CEST MRI and dynamic correction: application to gagCEST at 7\u202fT. Magn Reson Med 81:573\u2013582","journal-title":"Magn Reson Med"},{"key":"558_CR22","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s10334-016-0544-5","volume":"29","author":"MM Schreiner","year":"2016","unstructured":"Schreiner MM, Zbyn S, Schmitt B et\u00a0al (2016) Reproducibility and regional variations of an improved gagCEST protocol for the in vivo evaluation of knee cartilage at 7\u202fT. Magn Reson Mater Phys Biol Med 29:513\u2013521","journal-title":"Magn Reson Mater Phys Biol Med"},{"key":"558_CR23","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1002\/mrm.23250","volume":"68","author":"A Singh","year":"2012","unstructured":"Singh A, Haris M, Cai KJ et\u00a0al (2012) Chemical exchange saturation transfer magnetic resonance imaging of human knee cartilage at 3\u202fT and 7\u202fT. Magn Reson Med 68:588\u2013594","journal-title":"Magn Reson Med"},{"key":"558_CR24","doi-asserted-by":"publisher","first-page":"2266","DOI":"10.1073\/pnas.0707666105","volume":"105","author":"W Ling","year":"2008","unstructured":"Ling W, Regatte RR, Navon G, Jerschow A (2008) Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST). Proc Natl Acad Sci USA 105:2266\u20132270","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"558_CR25","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1148\/radiol.11101841","volume":"260","author":"B Schmitt","year":"2011","unstructured":"Schmitt B, Zbyn S, Stelzeneder D et al (2011) Cartilage quality assessment by using Glycosaminoglycan chemical exchange saturation transfer and na-23 MR imaging at 7\u202fT. Radiology 260:257\u2013264","journal-title":"Radiology"},{"key":"558_CR26","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1007\/s00264-017-3434-1","volume":"41","author":"U Koller","year":"2017","unstructured":"Koller U, Apprich S, Schmitt B, Windhager R, Trattnig S (2017) Evaluating the cartilage adjacent to the site of repair surgery with glycosaminoglycan-specific magnetic resonance imaging. Int Orthop 41:969\u2013974","journal-title":"Int Orthop"},{"key":"558_CR27","doi-asserted-by":"publisher","first-page":"2874","DOI":"10.1007\/s00330-017-5277-y","volume":"28","author":"S Brinkhof","year":"2018","unstructured":"Brinkhof S, Nizak R, Khlebnikov V, Prompers JJ, Klomp DWJ, Saris DBF (2018) Detection of early cartilage damage: feasibility and potential of gagCEST imaging at 7T. Eur Radiol 28:2874\u20132881","journal-title":"Eur Radiol"},{"key":"558_CR28","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1055\/s-2004-861764","volume":"8","author":"TJ Mosher","year":"2004","unstructured":"Mosher TJ, Dardzinski BJ (2004) Cartilage MRI T2 relaxation time mapping: Overview and applications. Semin Musculoskelet Radiol 8:355\u2013368","journal-title":"Semin. Musculoskelet. Radiol."},{"key":"558_CR29","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1002\/jmri.1150","volume":"14","author":"HE Smith","year":"2001","unstructured":"Smith HE, Mosher TJ, Dardzinski BJ et\u00a0al (2001) Spatial variation in cartilage T2 of the knee. J\u00a0Magn Reson Imaging 14:50\u201355","journal-title":"J Magn Reson Imaging"},{"key":"558_CR30","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1002\/acr.20672","volume":"64","author":"T Baum","year":"2012","unstructured":"Baum T, Joseph GB, Arulanandan A et al (2012) Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: data from the Osteoarthritis Initiative. Arthritis Care Res (hoboken) 64:248\u2013255","journal-title":"Arthritis Care Res (hoboken)"},{"key":"558_CR31","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.1002\/art.20473","volume":"50","author":"TJ Mosher","year":"2004","unstructured":"Mosher TJ, Liu Y, Yang QX et\u00a0al (2004) Age dependency of cartilage magnetic resonance imaging T2 relaxation times in asymptomatic women. Arthritis Rheum 50:2820\u20132828","journal-title":"Arthritis Rheum"},{"key":"558_CR32","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1002\/jmri.20013","volume":"19","author":"TJ Mosher","year":"2004","unstructured":"Mosher TJ, Collins CM, Smith HE et\u00a0al (2004) Effect of gender on in vivo cartilage magnetic resonance imaging T2 mapping. J\u00a0Magn Reson Imaging 19:323\u2013328","journal-title":"J Magn Reson Imaging"},{"key":"558_CR33","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/acr.21741","volume":"65","author":"T Baum","year":"2013","unstructured":"Baum T, Joseph GB, Nardo L et al (2013) Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a\u00a0longitudinal, observational multicenter study. Arthritis Care Res (hoboken) 65:23\u201333","journal-title":"Arthritis Care Res (hoboken)"},{"key":"558_CR34","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1002\/jmri.24630","volume":"41","author":"AT Serebrakian","year":"2015","unstructured":"Serebrakian AT, Poulos T, Liebl H et\u00a0al (2015) Weight loss over 48\u00a0months is associated with reduced progression of cartilage T2 relaxation time values: data from the osteoarthritis initiative. J\u00a0Magn Reson Imaging 41:1272\u20131280","journal-title":"J Magn Reson Imaging"},{"key":"558_CR35","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1007\/s00330-009-1689-7","volume":"20","author":"KM Friedrich","year":"2010","unstructured":"Friedrich KM, Shepard T, Chang G et\u00a0al (2010) Does joint alignment affect the T2 values of cartilage in patients with knee osteoarthritis? Eur Radiol 20:1532\u20131538","journal-title":"Eur Radiol"},{"key":"558_CR36","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1148\/radiol.2341040041","volume":"234","author":"TJ Mosher","year":"2005","unstructured":"Mosher TJ, Smith HE, Collins C et\u00a0al (2005) Change in knee cartilage T2 at MR imaging after running: A feasibility study. Radiology 234:245\u2013249","journal-title":"Radiology"},{"key":"558_CR37","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.joca.2009.11.011","volume":"18","author":"TJ Mosher","year":"2010","unstructured":"Mosher TJ, Liu Y, Torok CM (2010) Functional cartilage MRI T2 mapping: evaluating the effect of age and training on knee cartilage response to running. Osteoarthr Cartil 18:358\u2013364","journal-title":"Osteoarthr Cartil"},{"key":"558_CR38","doi-asserted-by":"publisher","first-page":"2248","DOI":"10.1002\/art.30419","volume":"63","author":"KK Hovis","year":"2011","unstructured":"Hovis KK, Stehling C, Souza RB et al (2011) Physical activity is associated with magnetic resonance imaging-based knee cartilage T2 measurements in asymptomatic subjects with and those without osteoarthritis risk factors. Arthritis Rheum 63:2248\u20132256","journal-title":"Arthritis Rheum"},{"key":"558_CR39","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1148\/radiol.09090596","volume":"254","author":"C Stehling","year":"2010","unstructured":"Stehling C, Liebl H, Krug R et al (2010) Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology 254:509\u2013520","journal-title":"Radiology"},{"key":"558_CR40","doi-asserted-by":"publisher","first-page":"1558","DOI":"10.1016\/j.joca.2013.06.022","volume":"21","author":"W Lin","year":"2013","unstructured":"Lin W, Alizai H, Joseph GB et\u00a0al (2013) Physical activity in relation to knee cartilage T2 progression measured with 3\u202fT MRI over a\u00a0period of 4 years: data from the Osteoarthritis Initiative. Osteoarthr Cartil 21:1558\u20131566","journal-title":"Osteoarthr Cartil"},{"key":"558_CR41","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1148\/radiol.12121413","volume":"267","author":"R Kijowski","year":"2013","unstructured":"Kijowski R, Blankenbaker DG, del Rio AM, Baer GS, Graf BK (2013) Evaluation of the articular cartilage of the knee joint: value of adding a\u00a0T2 mapping sequence to a\u00a0routine MR imaging protocol. Radiology 267:503\u2013513","journal-title":"Radiology"},{"key":"558_CR42","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1148\/radiol.2471070688","volume":"247","author":"GH Welsch","year":"2008","unstructured":"Welsch GH, Mamisch TC, Domayer SE et al (2008) Cartilage T2 assessment at 3\u2011T MR imaging: in vivo differentiation of normal hyaline cartilage from reparative tissue after two cartilage repair procedures\u2014initial experience. Radiology 247:154\u2013161","journal-title":"Radiology"},{"key":"558_CR43","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1097\/01.rli.0000262088.67368.49","volume":"42","author":"S Trattnig","year":"2007","unstructured":"Trattnig S, Mamisch TC, Welsch GH et al (2007) Quantitative T2 mapping of matrix-associated autologous chondrocyte transplantation at 3 Tesla: an in vivo cross-sectional study. Invest Radiol 42:442\u2013448","journal-title":"Invest Radiol"},{"key":"558_CR44","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1002\/mrm.1910380602","volume":"38","author":"U Duvvuri","year":"1997","unstructured":"Duvvuri U, Reddy R, Patel SD, Kaufman JH, Kneeland JB, Leigh JS (1997) T\u20111 rho-relaxation in articular cartilage: Effects of enzymatic degradation. Magn Reson Med 38:863\u2013867","journal-title":"Magn Reson Med"},{"key":"558_CR45","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1016\/j.jmr.2004.05.003","volume":"169","author":"V Mlynarik","year":"2004","unstructured":"Mlynarik V, Szomolanyi P, Toffanin R, Vittur F, Trattnig S (2004) Transverse relaxation mechanisms in articular cartilage. J\u00a0Magn Reson 169:300\u2013307","journal-title":"J Magn Reson"},{"key":"558_CR46","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1002\/jmri.20536","volume":"23","author":"RR Regatte","year":"2006","unstructured":"Regatte RR, Akella SVS, Lonner JH, Kneeland JB, Reddy R (2006) T\u20111p relaxation mapping in human osteoarthritis (OA) cartilage: Comparison of T\u20111p with T\u20112. J\u00a0Magn Reson Imaging 23:547\u2013553","journal-title":"J Magn Reson Imaging"},{"key":"558_CR47","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1080\/02841859709172133","volume":"38","author":"SK Koskinen","year":"1997","unstructured":"Koskinen SK, YlaOutinen H, Aho HJ, Komu MES (1997) Magnetization transfer and spin lock MR imaging of patellar cartilage degeneration at 0.1\u202fT. Acta Radiol 38:1071\u20131075","journal-title":"Acta Radiol"},{"key":"558_CR48","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1053\/joca.2002.0826","volume":"10","author":"U Duvvuri","year":"2002","unstructured":"Duvvuri U, Kudchodkar S, Reddy R, Leigh JS (2002) T\u20111 rho relaxation can assess longitudinal proteoglycan loss from articular cartilage in vitro. Osteoarthr Cartil 10:838\u2013844","journal-title":"Osteoarthr Cartil"},{"key":"558_CR49","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1002\/mrm.10710","volume":"51","author":"NM Menezes","year":"2004","unstructured":"Menezes NM, Gray ML, Hartke JR, Burstein D (2004) T\u20112 and T\u20111, MRI in articular cartilage systems. Magn Reson Med 51:503\u2013509","journal-title":"Magn Reson Med"},{"key":"558_CR50","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/(SICI)1522-2586(199910)10:4<497::AID-JMRI1>3.0.CO;2-T","volume":"10","author":"V Mlynarik","year":"1999","unstructured":"Mlynarik V, Trattnig S, Huber M, Zembsch A, Imhof H (1999) The role of relaxation times in monitoring proteoglycan depletion in articular cartilage. J\u00a0Magn Reson Imaging 10:497\u2013502","journal-title":"J. Magn. Reson. Imaging"},{"key":"558_CR51","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1007\/s00330-008-1107-6","volume":"19","author":"R Stahl","year":"2009","unstructured":"Stahl R, Luke A, Li XJ et al (2009) T1rho, T\u20112 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients\u2014a 3.0-Tesla MRI study. Eur Radiol 19:132\u2013143","journal-title":"Eur Radiol"},{"key":"558_CR52","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.acra.2013.12.010","volume":"21","author":"LG Wang","year":"2014","unstructured":"Wang LG, Regatte RR (2014) Quantitative mapping of human cartilage at 3.0T: parallel changes in T\u20112, T\u20111p, and dGEMRIC. Acad Radiol 21:463\u2013471","journal-title":"Acad Radiol"},{"key":"558_CR53","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1016\/j.ejrad.2013.05.010","volume":"82","author":"LG Wang","year":"2013","unstructured":"Wang LG, Vieira RL, Rybak LD et\u00a0al (2013) Relationship between knee alignment and T1 rho values of articular cartilage and menisci in patients with knee osteoarthritis. Eur J Radiol 82:1946\u20131952","journal-title":"Eur J Radiol"},{"key":"558_CR54","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1177\/0363546513495167","volume":"41","author":"DU Thuillier","year":"2013","unstructured":"Thuillier DU, Souza RB, Wu S, Luke A, Li XJ, Feeley BT (2013) T\u20111 rho imaging demonstrates early changes in the lateral patella in patients with Patellofemoral pain and Maltracking. Am J Sports Med 41:1813\u20131818","journal-title":"Am. J. Sports Med."},{"key":"558_CR55","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.knee.2012.10.018","volume":"20","author":"RB Souza","year":"2013","unstructured":"Souza RB, Feeley BT, Zarins ZA, Link TM, Li XJ, Majumdar S (2013) T1rho MRI relaxation in knee OA subjects with varying sizes of cartilage lesions. Knee 20:113\u2013119","journal-title":"Knee"},{"key":"558_CR56","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1016\/j.joca.2010.07.012","volume":"18","author":"ZA Zarins","year":"2010","unstructured":"Zarins ZA, Bolbos RI, Pialat JB et\u00a0al (2010) Cartilage and meniscus assessment using T1rho and T2 measurements in healthy subjects and patients with osteoarthritis. Osteoarthr Cartil 18:1408\u20131416","journal-title":"Osteoarthr Cartil"},{"key":"558_CR57","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.joca.2008.05.016","volume":"17","author":"RI Bolbos","year":"2009","unstructured":"Bolbos RI, Link TM, Ma CB, Majumdar S, Li X (2009) T1 rho relaxation time of the meniscus and its relationship with T1 rho of adjacent cartilage in knees with acute ACL injuries at 3\u202fT. Osteoarthr Cartil 17:12\u201318","journal-title":"Osteoarthr Cartil"},{"key":"558_CR58","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1148\/radiol.10101006","volume":"258","author":"XJ Li","year":"2011","unstructured":"Li XJ, Kuo D, Theologis A et al (2011) Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1(rho) and T2-initial experience with 1\u2011year follow-up. Radiology 258:505\u2013514","journal-title":"Radiology"}],"container-title":["Der Radiologe"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00117-019-0558-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00117-019-0558-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00117-019-0558-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T23:30:24Z","timestamp":1591745424000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00117-019-0558-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,11]]},"references-count":58,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["558"],"URL":"https:\/\/doi.org\/10.1007\/s00117-019-0558-x","relation":{},"ISSN":["0033-832X","1432-2102"],"issn-type":[{"value":"0033-832X","type":"print"},{"value":"1432-2102","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,11]]},"assertion":[{"value":"11 June 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"S.\u00a0Trattnig, M.\u00a0Raudner, M.\u00a0Schreiner, F.\u00a0Roemer und K.\u00a0Bohndorf geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}