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F\u00fcr das Jahr 2022 wurden ca.\u00a059.700 Neuerkrankungen an Lungenkrebs prognostiziert.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>TNM-Schema zur Stadieneinteilung<\/jats:title>\n                <jats:p>Die korrekte Ausbreitungsdiagnostik ist f\u00fcr die Therapieplanung, Prognoseabsch\u00e4tzung und zuk\u00fcnftige Analysen von grundlegender Bedeutung. Die Stadieneinteilung des Lungenkarzinoms erfolgt nach dem TNM-Schema der Union for International Cancer Control (UICC). F\u00fcr die Stadien IIB\u2013IIIC wird der Lymphknotenbefall zur Differenzierung herangezogen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Lymphknotenstationen beim Lungenkarzinom<\/jats:title>\n                <jats:p>Die Kenntnis der intrathorakalen Lymphknotenstationen ist f\u00fcr die genaue Klassifikation von entscheidender Bedeutung, und deren Befall hat unmittelbare Auswirkungen auf die Therapie. Die International Association for the Study of Lung Cancer (IASLC) hat eine vereinheitlichte Lymphknotenkarte vorgeschlagen, die sich durch ihre exakten anatomischen Definitionen auszeichnet und in der aktuellen S3-Leitlinie f\u00fcr das Lungenkarzinom ber\u00fccksichtigt wird. Der Lymphknotenbefall wird abh\u00e4ngig vom Ausma\u00df in N0\u2013N3 stratifiziert. Je nach Lokalisation des Prim\u00e4rtumors lassen sich bevorzugte Metastasierungspfade nachweisen. Die Krankheitslast hat einen gr\u00f6\u00dferen Einfluss auf das \u00dcberleben als die Lokalisation der Metastasen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ausbreitungsdiagnostik beim Lungenkarzinom<\/jats:title>\n                <jats:p>Mit der Computertomographie (CT) kann die Operabilit\u00e4t des Prim\u00e4rtumors meistens sicher beurteilt werden. Invasive Verfahren zur Diagnosesicherung durch Probengewinnung sollten erst im Anschluss an nichtinvasive Diagnostik eingesetzt werden.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Empfehlung f\u00fcr die Praxis<\/jats:title>\n                <jats:p>In der aktuellen Leitlinie des Lungenkarzinoms wird bei allen Patienten mit nichtkleinzelligem Lungenkarzinom, die einer kurativen Resektion zugef\u00fchrt werden, eine systematische Lymphknotenresektion empfohlen.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00117-022-01102-7","type":"journal-article","created":{"date-parts":[[2023,1,2]],"date-time":"2023-01-02T12:02:59Z","timestamp":1672660979000},"page":"187-194","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bronchialkarzinom: Metastasierungspfade und Involvierung hil\u00e4rer und mediastinaler Lymphknoten"],"prefix":"10.1007","volume":"63","author":[{"given":"Julian","family":"Glandorf","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Vogel-Claussen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,1,2]]},"reference":[{"key":"1102_CR1","doi-asserted-by":"publisher","first-page":"2981","DOI":"10.1200\/JCO.2000.18.16.2981","volume":"18","author":"F Andre","year":"2000","unstructured":"Andre\u00a0F, Grunenwald\u00a0D, Pignon\u00a0J\u2011P et al (2000) Survival of patients with resected N2 non\u2013small-cell lung cancer: evidence for a\u00a0subclassification and implications. 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