{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T13:18:14Z","timestamp":1768483094946,"version":"3.49.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T00:00:00Z","timestamp":1721174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100009572","name":"University of St.Gallen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100009572","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiologie"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec>\n                <jats:title>Hintergrund<\/jats:title>\n                <jats:p>Dank Mammographie-Screening-Programmen (MSP) kann Brustkrebs erwiesenerma\u00dfen in fr\u00fcheren Stadien entdeckt werden, was weniger eingreifende Therapien erlaubt und zu einem besseren \u00dcberleben f\u00fchrt. Kritisch beurteilt werden die betr\u00e4chtliche Zahl der Intervallkarzinome (IBC) und zus\u00e4tzlich notwendige Abkl\u00e4rungen, bei denen sich in der Mehrzahl erweist, dass kein Karzinom vorliegt.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Fragestellung<\/jats:title>\n                <jats:p>In den letzten Jahren wurden von Firmen und Universit\u00e4ten mittels maschinellem Lernen (ML) leistungsf\u00e4hige Algorithmen entwickelt, welche erstaunliche F\u00e4higkeiten zum Lesen von Mammographien zeigen. K\u00f6nnen dadurch MSP qualitativ verbessert werden?<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methode<\/jats:title>\n                <jats:p>Mittels der Software ProFound AI\u00ae (iCAD, Nashua, NH, USA) wurden retrospektiv die urspr\u00fcnglichen Screening-Mammographien von 251 F\u00e4llen mit Intervallkarzinom untersucht und die Resultate (Case-Score, Risk-Score) mit denen einer Kontrollgruppe verglichen. Dar\u00fcber hinaus wurde die relevante aktuelle Literatur studiert.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Die Verteilung des Case-Score wie auch des Risk-Score der Mammographien mit sp\u00e4terem IBC war signifikant zu h\u00f6herem Risiko verschoben im Vergleich zur Kontrolle, \u00e4hnlich wie in anderen Studien.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Retrospektive Studien, wie auch eigene Daten zeigen, dass m\u00f6glicherweise k\u00fcnstliche Intelligenz (KI) in Zukunft das Vorgehen bei MSP \u00e4ndern wird in Richtung personalisiertem Screening, mit deutlicher Entlastung der Radiologen, weniger Abkl\u00e4rungen und einer verminderten Anzahl von IBC. F\u00fcr eine solche Umsetzung braucht es die Resultate prospektiver Studien.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00117-024-01345-6","type":"journal-article","created":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T11:02:16Z","timestamp":1721214136000},"page":"773-778","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Der m\u00f6gliche Nutzen k\u00fcnstlicher Intelligenz in einem organisierten bev\u00f6lkerungsbezogenen Screeningprogramm","The possible benefit of artificial intelligence in an organized population-related screening program"],"prefix":"10.1007","volume":"64","author":[{"given":"R.","family":"Morant","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gr\u00e4wingholt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Subelack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Kuklinski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Blum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Eichenberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Geissler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,17]]},"reference":[{"issue":"1_suppl","key":"1345_CR1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1258\/jms.2012.012080","volume":"19","author":"S Njor","year":"2012","unstructured":"Njor\u00a0S, Nystr\u00f6m\u00a0L, Moss\u00a0S et\u00a0al (2012) Breast Cancer Mortality in Mammographic Screening in Europe: A\u00a0Review of Incidence-Based Mortality Studies. 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A.\u00a0Gr\u00e4wingholt hat Beratungs- und Vortragshonorare von iCAD erhalten. J.\u00a0Subelack, D.\u00a0Kuklinski, J.\u00a0Vogel und A.\u00a0Geissler geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"Diese retrospektiven Untersuchung wurde der zust\u00e4ndigen Ethikkommission Ostschweiz vorgelegt und von dieser als Qualit\u00e4tskontrolle erachtet, welche ohne spezielle Genehmigung durchgef\u00fchrt werden darf. Die Teilnehmerinnen am Mammographie-Fr\u00fcherkennungsprogramm \u201edonna\u201c gaben routinem\u00e4ssig ihre schriftliche Einwilligung daf\u00fcr, dass Daten des MSP an das Krebsregister gesandt werden d\u00fcrfen zur Erfassung von Intervallkarzinomen.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}