{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:38:14Z","timestamp":1762900694614,"version":"3.40.4"},"reference-count":9,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T00:00:00Z","timestamp":1742601600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T00:00:00Z","timestamp":1742601600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"University of Innsbruck and Medical University of Innsbruck"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiologie"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title>\n          <jats:p>Die Lymphgef\u00e4\u00dfe sind ein unidirektionales, zentripetales System, das interstitielle Fl\u00fcssigkeit aus Geweben und Organen sammelt und in das Venensystem leitet. Die Lymphgef\u00e4\u00dfe lassen sich in 4\u00a0Typen gliedern: initiale Lymphgef\u00e4\u00dfe, Pr\u00e4kollektoren, Kollektoren und Lymphst\u00e4mme. Initiale Lymphgef\u00e4\u00dfe formen Netzwerke mit gr\u00f6\u00dferen Maschen als Blutkapillaren und sind mit speziellem Endothel ausgekleidet. Sie weisen interendotheliale \u00d6ffnungen auf, welche den Austausch mit dem umgebenden Gewebe erm\u00f6glichen. Diese Gef\u00e4\u00dfe sind zudem mit charakteristischen Markern wie VEGFR\u20113, Podoplanin und LYVE\u20111 ausgestattet. Pr\u00e4kollektoren verf\u00fcgen \u00fcber glatte Muskelzellen, die noch unregelm\u00e4\u00dfig angeordnet sind, und parietale Klappen, die den zentripetalen Lymphfluss f\u00f6rdern. Kollektoren haben eine durchgehende Media aus spiralig angeordneten Muskelfasern, die eine Verengung und Kontraktion der Gef\u00e4\u00dfe erm\u00f6glicht. Diese Kontraktion f\u00fchrt zum Transport der Lymphe durch einzelne Lymphangienabschnitte. Lymphst\u00e4mme bilden den n\u00e4chsten Abschnitt und m\u00fcnden oft in den Ductus thoracicus, der sich in das Venensystem \u00f6ffnet. Lymphst\u00e4mme enthalten zunehmend strukturierte Abschnitte und Klappen zur weiteren Regulation des Lymphflusses.<\/jats:p>\n          <jats:p>Lymphknoten sind in den Verlauf der Kollektoren und St\u00e4mme eingebaut und dienen als Kontrollstationen f\u00fcr Krankheitserreger und die Regulation des kolloidosmotischen Drucks der Lymphe. Sie sind in Gruppen organisiert und haben eine spezifische Struktur mit Kortex, Medulla und eingelagerten B\u2011 und T\u2011Lymphozyten. Das lymphatische Hauptsystem transportiert die Lymphe durch segmentale Verbindungen und Anastomosen. Der Ductus thoracicus m\u00fcndet in den linken Venenwinkel und verbindet sich mit weiteren Lymphgef\u00e4\u00dfen. Die Entwicklungsgeschichte und Variationen des Ductus thoracicus f\u00fchren zu gelegentlichen anatomischen Abweichungen.<\/jats:p>","DOI":"10.1007\/s00117-025-01432-2","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T11:40:16Z","timestamp":1742730016000},"page":"301-306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Anatomie und Physiologie des\u00a0Lymphgef\u00e4\u00dfsystems","Anatomy and physiology of the lymph system"],"prefix":"10.1007","volume":"65","author":[{"given":"Erich","family":"Brenner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,22]]},"reference":[{"key":"1432_CR1","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-662-61452-5_1","volume-title":"Angewandte Lymphologie : Grundlagen \u2013 Alltag \u2013 Perspektiven","author":"E Brenner","year":"2023","unstructured":"Brenner\u00a0E (2023) Weshalb hat der Mensch Lymphgef\u00e4\u00dfe? In: Cornely\u00a0ME, Marsch\u00a0WC, Brenner\u00a0E (Hrsg) Angewandte Lymphologie : Grundlagen \u2013 Alltag \u2013 Perspektiven. Springer, Berlin, Heidelberg, S\u00a03\u201330 https:\/\/doi.org\/10.1007\/978-3-662-61452-5_1"},{"issue":"10","key":"1432_CR2","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1084\/jem.20062596","volume":"204","author":"P Baluk","year":"2007","unstructured":"Baluk\u00a0P, Fuxe\u00a0J, Hashizume\u00a0H, Romano\u00a0T, Lashnits\u00a0E, Butz\u00a0S, Vestweber\u00a0D, Corada\u00a0M, Molendini\u00a0C, Dejana\u00a0E, McDonald\u00a0DM (2007) Functionally specialized junctions between endothelial cells of lymphatic vessels. 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J\u00a0Cell Biol 36(1):129\u2013149. https:\/\/doi.org\/10.1083\/jcb.36.1.129","journal-title":"J Cell Biol"},{"key":"1432_CR5","first-page":"483","volume":"91","author":"E Horstmann","year":"1952","unstructured":"Horstmann\u00a0E (1952) \u00dcber die funktionelle Struktur der mesenterialen Lymphgef\u00e4\u00dfe. Morphol Jahrb 91:483\u2013510","journal-title":"Morphol Jahrb"},{"key":"1432_CR6","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1002\/9781118430309.ch75","volume-title":"Bergman\u2019s Comprehensive Encyclopedia of Human Anatomic Variation","author":"Y-B Song","year":"2016","unstructured":"Song\u00a0Y\u2011B (2016) Thoracic Duct, Cisterna Chyli, and Right Lymphatic Duct. In: Tubbs\u00a0RS, Shoja\u00a0MM, Loukas\u00a0M (Hrsg) Bergman\u2019s Comprehensive Encyclopedia of Human Anatomic Variation. 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