{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:09:50Z","timestamp":1774440590036,"version":"3.50.1"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiologie"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00117-026-01585-8","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:45:29Z","timestamp":1772189129000},"page":"241-248","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["MRT-Bildgebung bei neurodegenerativen Parkinson-Syndromen","MRI in neurodegenerative Parkinsonian syndromes"],"prefix":"10.1007","volume":"66","author":[{"given":"Nils","family":"Schr\u00f6ter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Rau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Reith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Martens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Gonzalez-Escamilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergiu","family":"Groppa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"1585_CR1","doi-asserted-by":"publisher","first-page":"125","DOI":"10.2463\/mrms.3.125","volume":"3","author":"M Adachi","year":"2004","unstructured":"Adachi\u00a0M, Kawanami\u00a0T, Ohshima\u00a0H et\u00a0al (2004) Morning glory sign: a particular MR finding in progressive supranuclear palsy. Magn Reson Med Sci 3:125\u2013132. https:\/\/doi.org\/10.2463\/mrms.3.125","journal-title":"Magn Reson Med Sci"},{"key":"1585_CR2","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1212\/WNL.0b013e31827f0fd1","volume":"80","author":"MJ Armstrong","year":"2013","unstructured":"Armstrong\u00a0MJ, Litvan\u00a0I, Lang\u00a0AE et\u00a0al (2013) Criteria for the diagnosis of corticobasal degeneration. Neurology 80:496\u2013503. https:\/\/doi.org\/10.1212\/WNL.0b013e31827f0fd1","journal-title":"Neurology"},{"key":"1585_CR3","doi-asserted-by":"publisher","first-page":"2284","DOI":"10.1016\/S0140-6736(21)00218-X","volume":"397","author":"BR Bloem","year":"2021","unstructured":"Bloem\u00a0BR, Okun\u00a0MS, Klein\u00a0C (2021) Parkinson\u2019s disease. Lancet 397:2284\u20132303. https:\/\/doi.org\/10.1016\/S0140-6736(21)00218-X","journal-title":"Lancet"},{"key":"1585_CR4","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1212\/WNL.53.4.795","volume":"53","author":"BF Boeve","year":"1999","unstructured":"Boeve\u00a0BF, Maraganore\u00a0DM, Parisi\u00a0JE et\u00a0al (1999) Pathologic heterogeneity in clinically diagnosed corticobasal degeneration. Neurology 53:795\u2013800","journal-title":"Neurology"},{"key":"1585_CR5","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1002\/mds.29760","volume":"39","author":"L Chougar","year":"2024","unstructured":"Chougar\u00a0L, Faucher\u00a0A, Faouzi\u00a0J et\u00a0al (2024) Contribution of MRI for the Early Diagnosis of Parkinsonism in Patients with Diagnostic Uncertainty. Mov Disord Clin Pract 39:825\u2013835. https:\/\/doi.org\/10.1002\/mds.29760","journal-title":"Movement Disorders"},{"key":"1585_CR6","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.3233\/JPD-181474","volume":"8","author":"ER Dorsey","year":"2018","unstructured":"Dorsey\u00a0ER, Sherer\u00a0T, Okun\u00a0MS, Bloem\u00a0BR (2018) The Emerging Evidence of the Parkinson Pandemic. J\u00a0Parkinsons Dis 8:S3\u2013S8. https:\/\/doi.org\/10.3233\/JPD-181474","journal-title":"J Parkinsons Dis"},{"key":"1585_CR7","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1002\/mds.28531","volume":"36","author":"R Gaurav","year":"2021","unstructured":"Gaurav\u00a0R, Yahia-Cherif\u00a0L, Pyatigorskaya\u00a0N et\u00a0al (2021) Longitudinal Changes in Neuromelanin MRI Signal in Parkinson\u2019s Disease: A Progression Marker. Mov Disord Clin Pract 36:1592\u20131602. https:\/\/doi.org\/10.1002\/mds.28531","journal-title":"Mov Disord"},{"key":"1585_CR8","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/978-1-0716-4083-8_11","volume-title":"Translational Methods for Parkinson\u2019s Disease and Atypical Parkinsonism Research","author":"G Gonzalez-Escamilla","year":"2025","unstructured":"Gonzalez-Escamilla\u00a0G, Othman\u00a0AE, Rotaru\u00a0L et\u00a0al (2025) Exploring Translational Paths in Parkinson\u2019s Disease and Atypical Parkinsonism with Human Structural MRI. In: Groppa\u00a0S, Schneider\u00a0SA (eds) Translational Methods for Parkinson\u2019s Disease and Atypical Parkinsonism Research. Springer US, New York, NY, pp\u00a0163\u2013173"},{"key":"1585_CR9","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1212\/01.wnl.0000203342.77115.bf","volume":"66","author":"K Gr\u00f6schel","year":"2006","unstructured":"Gr\u00f6schel\u00a0K, Kastrup\u00a0A, Litvan\u00a0I, Schulz\u00a0JB (2006) Penguins and hummingbirds: Midbrain atrophy in progressive supranuclear palsy. Neurology 66:949\u2013950. https:\/\/doi.org\/10.1212\/01.wnl.0000203342.77115.bf","journal-title":"Neurology"},{"key":"1585_CR10","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1002\/mdc3.13736","volume":"10","author":"A Grossauer","year":"2023","unstructured":"Grossauer\u00a0A, M\u00fcller\u00a0C, Hussl\u00a0A et\u00a0al (2023) Dorsolateral Nigral Hyperintensity on 1.5 T Versus 3 T Susceptibility-Weighted Magnetic Resonance Imaging in Neurodegenerative Parkinsonism. Mov Disord Clin Pract 10:914\u2013921. https:\/\/doi.org\/10.1002\/mdc3.13736","journal-title":"Mov Disord Clin Pract"},{"key":"1585_CR11","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1002\/mdc3.13736","volume":"10","author":"A Grossauer","year":"2023","unstructured":"Grossauer\u00a0A, M\u00fcller\u00a0C, Hussl\u00a0A et\u00a0al (2023) Dorsolateral Nigral Hyperintensity on 1.5 T Versus 3 T Susceptibility-Weighted Magnetic Resonance Imaging in Neurodegenerative Parkinsonism. Mov Disord Clin Pract 10:914\u2013921. https:\/\/doi.org\/10.1002\/mdc3.13736","journal-title":"Mov Disord Clin Pract"},{"key":"1585_CR12","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00500","author":"S Heinzel","year":"2018","unstructured":"Heinzel\u00a0S, Berg\u00a0D, Binder\u00a0S et\u00a0al (2018) Do We Need to Rethink the Epidemiology and Healthcare Utilization of Parkinson\u2019s Disease in Germany? Front Neurol. https:\/\/doi.org\/10.3389\/fneur.2018.00500","journal-title":"Front Neurol"},{"key":"1585_CR13","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26987","author":"GU H\u00f6glinger","year":"2017","unstructured":"H\u00f6glinger\u00a0GU, Respondek\u00a0G, Stamelou\u00a0M et\u00a0al (2017) Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria. Mov Disord Clin Pract. https:\/\/doi.org\/10.1002\/mds.26987","journal-title":"Movement Disorders"},{"key":"1585_CR14","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-025-02921-3","author":"WH Jost","year":"2025","unstructured":"Jost\u00a0WH, Rau\u00a0A, Brumberg\u00a0J et\u00a0al (2025) Neuroimaging in multiple system atrophy: clinical implications and novel developments. J\u00a0Neural Transm. https:\/\/doi.org\/10.1007\/s00702-025-02921-3","journal-title":"J Neural Transm"},{"key":"1585_CR15","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20180842","volume":"92","author":"EY Kim","year":"2019","unstructured":"Kim\u00a0EY, Sung\u00a0YH, Lee\u00a0J (2019) Nigrosome 1 imaging: technical considerations and clinical applications. Br J Radiol 92:20180842. https:\/\/doi.org\/10.1259\/bjr.20180842","journal-title":"Br J Radiol"},{"key":"1585_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11102701","volume":"11","author":"N Madetko","year":"2022","unstructured":"Madetko\u00a0N, Alster\u00a0P, Kuty\u0142owski\u00a0M et\u00a0al (2022) Is MRPI 2.0 More Useful than MRPI and M\/P Ratio in Differential Diagnosis of PSP\u2011P with Other Atypical Parkinsonisms? J\u00a0Clin Med 11:2701. https:\/\/doi.org\/10.3390\/jcm11102701","journal-title":"J Clin Med"},{"key":"1585_CR17","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1212\/WNL.0b013e318292a2d2","volume":"80","author":"LA Massey","year":"2013","unstructured":"Massey\u00a0LA, J\u00e4ger\u00a0HR, Paviour\u00a0DC et\u00a0al (2013) The midbrain to pons ratio. Neurology 80:1856\u20131861. https:\/\/doi.org\/10.1212\/WNL.0b013e318292a2d2","journal-title":"Neurology"},{"key":"1585_CR18","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1159\/000350291","volume":"70","author":"K Matsuura","year":"2013","unstructured":"Matsuura\u00a0K, Maeda\u00a0M, Yata\u00a0K et\u00a0al (2013) Neuromelanin magnetic resonance imaging in Parkinson\u2019s disease and multiple system atrophy. Eur Neurol 70:70\u201377. https:\/\/doi.org\/10.1159\/000350291","journal-title":"Eur Neurol"},{"key":"1585_CR19","doi-asserted-by":"publisher","first-page":"3072","DOI":"10.1093\/brain\/awaf151","volume":"148","author":"N Mongay-Ochoa","year":"2025","unstructured":"Mongay-Ochoa\u00a0N, Gonzalez-Escamilla\u00a0G, Fleischer\u00a0V et\u00a0al (2025) Structural covariance analysis for neurodegenerative and neuroinflammatory brain disorders. Brain Commun 148:3072\u20133084. https:\/\/doi.org\/10.1093\/brain\/awaf151","journal-title":"Brain"},{"key":"1585_CR20","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1056\/NEJMoa2202867","volume":"387","author":"G Pagano","year":"2022","unstructured":"Pagano\u00a0G, Taylor\u00a0KI, Anzures-Cabrera\u00a0J et\u00a0al (2022) Trial of Prasinezumab in Early-Stage Parkinson\u2019s Disease. New England Journal of Medicine 387:421\u2013432. https:\/\/doi.org\/10.1056\/NEJMoa2202867","journal-title":"New England Journal of Medicine"},{"key":"1585_CR21","unstructured":"Paulus W, Krauss JK, et\u00a0al. Leitlinie Normaldruckhydrocephalus. Deutsche Gesellschaft f\u00fcr Neurologie, Hrsg. Leitlinien f\u00fcr Diagnostik und Therapie in der Neurologie"},{"key":"1585_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.2202","volume":"11","author":"J Prasuhn","year":"2021","unstructured":"Prasuhn\u00a0J, Neumann\u00a0A, Strautz\u00a0R et\u00a0al (2021) Clinical MR imaging in Parkinson\u2019s disease: How useful is the swallow tail sign? Brain Behav 11:e02202. https:\/\/doi.org\/10.1002\/brb3.2202","journal-title":"Brain Behav"},{"key":"1585_CR23","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1148\/radiol.2453061703","volume":"246","author":"A Quattrone","year":"2008","unstructured":"Quattrone\u00a0A, Nicoletti\u00a0G, Messina\u00a0D et\u00a0al (2008) MR imaging index for differentiation of progressive supranuclear palsy from Parkinson disease and the Parkinson variant of multiple system atrophy. Radiol Imaging Cancer 246:214\u2013221. https:\/\/doi.org\/10.1148\/radiol.2453061703","journal-title":"Radiology"},{"key":"1585_CR24","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1002\/mds.29661","volume":"39","author":"A Rau","year":"2024","unstructured":"Rau\u00a0A, Hosp\u00a0JA, Rijntjes\u00a0M et\u00a0al (2024) Cerebellar, Not Nigrostriatal Degeneration Impairs Dexterity in Multiple System Atrophy. Mov Disord Clin Pract 39:130\u2013140. https:\/\/doi.org\/10.1002\/mds.29661","journal-title":"Movement Disorders"},{"key":"1585_CR25","doi-asserted-by":"publisher","unstructured":"Rau\u00a0A, Philipsen\u00a0L, Frings\u00a0L et\u00a0al (2025) Hippocampus and basal forebrain degeneration differentially impact cognition in Lewy body spectrum disorders. Brain Communawaf070. https:\/\/doi.org\/10.1093\/brain\/awaf070","DOI":"10.1093\/brain\/awaf070"},{"key":"1585_CR26","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1007\/s00234-024-03432-w","volume":"66","author":"K Sakurai","year":"2024","unstructured":"Sakurai\u00a0K, Tokumaru\u00a0AM, Yoshida\u00a0M et\u00a0al (2024) Conventional magnetic resonance imaging key features for distinguishing pathologically confirmed corticobasal degeneration from its mimics: a retrospective analysis of the J\u2011VAC study. Neuroradiology 66:1917\u20131929. https:\/\/doi.org\/10.1007\/s00234-024-03432-w","journal-title":"Neuroradiology"},{"key":"1585_CR27","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1007\/s00702-023-02634-5","volume":"130","author":"N Schr\u00f6ter","year":"2023","unstructured":"Schr\u00f6ter\u00a0N, van Eimeren\u00a0T, Classen\u00a0J et\u00a0al (2023) Significance of clinical symptoms and red flags in early differential diagnosis of Parkinson\u2019s disease and atypical Parkinsonian syndromes. J\u00a0Neural Transm 130:839\u2013846. https:\/\/doi.org\/10.1007\/s00702-023-02634-5","journal-title":"J Neural Transm"},{"key":"1585_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41531-022-00401-z","volume":"8","author":"N Schr\u00f6ter","year":"2022","unstructured":"Schr\u00f6ter\u00a0N, Rijntjes\u00a0M, Urbach\u00a0H et\u00a0al (2022) Disentangling nigral and putaminal contribution to motor impairment and levodopa response in Parkinson\u2019s disease. NPJ Parkinsons Dis 8:1\u20138. https:\/\/doi.org\/10.1038\/s41531-022-00401-z","journal-title":"npj Parkinsons Dis"},{"key":"1585_CR29","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1002\/mdc3.14304","volume":"12","author":"VS Tseriotis","year":"2025","unstructured":"Tseriotis\u00a0VS, Eleftheriadou\u00a0K, Mavridis\u00a0T et\u00a0al (2025) Is the Swallow Tail Sign a Useful Imaging Biomarker in Clinical Neurology? A Systematic Review. Mov Disord Clin Pract 12:134\u2013147. https:\/\/doi.org\/10.1002\/mdc3.14304","journal-title":"Movement Disorders Clinical Practice"},{"key":"1585_CR30","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1001\/jamaneurol.2025.0112","volume":"82","author":"DE Vaillancourt","year":"2025","unstructured":"Vaillancourt\u00a0DE, Barmpoutis\u00a0A, Wu\u00a0SS et\u00a0al (2025) Automated Imaging Differentiation for Parkinsonism. JAMA Neurol 82:495\u2013505. https:\/\/doi.org\/10.1001\/jamaneurol.2025.0112","journal-title":"JAMA Neurol"},{"key":"1585_CR31","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1002\/mds.29527","volume":"38","author":"MP Wattjes","year":"2023","unstructured":"Wattjes\u00a0MP, Huppertz\u00a0HJ, Mahmoudi\u00a0N et\u00a0al (2023) Brain MRI in Progressive Supranuclear Palsy with Richardson\u2019s Syndrome and Variant Phenotypes. Mov Disord Clin Pract 38:1891\u20131900. https:\/\/doi.org\/10.1002\/mds.29527","journal-title":"Mov Disord"},{"key":"1585_CR32","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1002\/mds.29005","volume":"37","author":"GK Wenning","year":"2022","unstructured":"Wenning\u00a0GK, Stankovic\u00a0I, Vignatelli\u00a0L et\u00a0al (2022) The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy. Mov Disord Clin Pract 37:1131\u20131148. https:\/\/doi.org\/10.1002\/mds.29005","journal-title":"Movement Disorders"},{"key":"1585_CR33","doi-asserted-by":"crossref","unstructured":"Zhou L, Li G, Zhang Y et\u00a0al. (2021) Increased free water in the substantia nigra in idiopathic REM sleep behaviour disorder. Brain 144:1488\u20131497. https:\/\/doi.org\/10.1093\/brain\/awab039","DOI":"10.1093\/brain\/awab039"}],"container-title":["Die Radiologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00117-026-01585-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00117-026-01585-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00117-026-01585-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T08:57:47Z","timestamp":1774429067000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00117-026-01585-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["1585"],"URL":"https:\/\/doi.org\/10.1007\/s00117-026-01585-8","relation":{},"ISSN":["2731-7048","2731-7056"],"issn-type":[{"value":"2731-7048","type":"print"},{"value":"2731-7056","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]},"assertion":[{"value":"30 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"N.\u00a0Schr\u00f6ter, A.\u00a0Rau, W.\u00a0Reith, D.\u00a0Martens, G.\u00a0Gonzalez-Escamilla und S.\u00a0Groppa geben an, dass kein Interessenkonflikt besteht.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Interessenkonflikt"}}]}}