{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T05:18:15Z","timestamp":1788499095289,"version":"build-2803163510"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/deed.de"}],"funder":[{"name":"Universit\u00e4tsklinikum Ulm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Radiologie"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Osteoporosis is frequently underdiagnosed in trauma patients. However, contrast-enhanced whole-body computed tomography (WBCT) in polytrauma care enables opportunistic assessment of bone status without additional radiation exposure. The aim of this study was to investigate whether vertebral, femoral, and dentomaxillofacial CT parameters can identify patients with documented osteopenia or osteoporosis and whether a\u00a0combined score improves classification.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>This retrospective, single-center study included 60\u00a0WBCT cases. Twenty patients with osteopenia or osteoporosis documented in their initial trauma report were compared with 20\u00a0age- and sex-matched reference patients and 20\u00a0younger patients. The final classification of bone status was based on an evaluation of patient records, including dual-energy X\u2011ray absorptiometry (DXA) data (where available), and medical history. Trabecular density was measured in the lumbar spine (L1\u2013L3), femoral neck, and maxillary alveolar ridge. Hard palate cortical thickness (HPT) was measured in millimeters. The whole-body osteoporosis screening score was defined as WBOS\u202f=\u2009\u0192(HPT, hip HU, lumbar HU).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Measurements of HPT, maxilla, hip, and lumbar spine decreased significantly in patients with osteopenia\/osteoporosis patients. The combined WBOS score demonstrated the best exploratory performance, with a\u00a0sensitivity of 100.0%, a\u00a0specificity of 97.1%, an accuracy of 98.3%, and an AUC of 0.994 at a\u00a0preliminary threshold of 361.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Opportunistic multisite assessment of bone status using WBCT in polytrauma appears feasible. The WBOS showed the best exploratory discrimination but requires further validation against DXA or quantitative CT before clinical implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00117-026-01654-y","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T04:42:47Z","timestamp":1788496967000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multisite opportunistic osteoporosis screening in polytrauma","Multiregionales opportunistisches Osteoporose-Screening im Polytrauma-CT"],"prefix":"10.1007","author":[{"given":"Daniela","family":"Kildal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tilmann","family":"Blasenbrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margrit-Ann","family":"Geibel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"issue":"4","key":"1654_CR1","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1055\/s-0043-1771037","volume":"27","author":"D Guenoun","year":"2023","unstructured":"Guenoun\u00a0D, Champsaur\u00a0P (2023) Opportunistic Computed Tomography Screening for Osteoporosis and Fracture. 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The study was conducted in accordance with the principles of the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The supplement containing this article is not sponsored by industry.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}}]}}