{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:51:57Z","timestamp":1791373917838,"version":"4.3.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T00:00:00Z","timestamp":1780617600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Urologie"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s00120-026-02857-w","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T19:45:42Z","timestamp":1780688742000},"page":"1073-1078","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endoskopische Enukleation bei Prostatavolumina \u2265\u202f200\u202fml: Aktuelle Evidenz, technische Herausforderungen und klinische Implikationen","Endoscopic enucleation for prostate volumes \u2265\u202f200\u202fml: current evidence, technical challenges, and clinical implications"],"prefix":"10.1007","volume":"65","author":[{"given":"Jonas","family":"Herrmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedrich O.","family":"Hartung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Lusuardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Netsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas R. W.","family":"Herrmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,5]]},"reference":[{"key":"2857_CR1","first-page":"6","volume":"28","author":"A Shvero","year":"2021","unstructured":"Shvero\u00a0A, Calio\u00a0B, Humphreys\u00a0MR, Das\u00a0AK (2021) HoLEP: the new gold standard for surgical treatment of benign prostatic hyperplasia. The Canadian journal of urology 28:6\u201310","journal-title":"The Canadian journal of urology"},{"key":"2857_CR2","first-page":"44","volume":"27","author":"AK Das","year":"2020","unstructured":"Das\u00a0AK, Han\u00a0TM, Hardacker\u00a0TJ (2020) Holmium laser enucleation of the prostate (HoLEP): size-independent gold standard for surgical management of benign prostatic hyperplasia. The Canadian journal of urology 27:44\u201350","journal-title":"The Canadian journal of urology"},{"key":"2857_CR3","unstructured":"Gravas\u00a0S, Cornu\u00a0JN, Gacci\u00a0M, Gratzke\u00a0C, Herrmann\u00a0TRW, Mamoulakis\u00a0C, Rieken\u00a0M, Speakman\u00a0MJ, Tikkinen\u00a0KAO (2023) EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS), incl. Benign Prostatic Obstruction (BPO)."},{"key":"2857_CR4","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-020-00985-0","volume":"21","author":"R Dornbier","year":"2020","unstructured":"Dornbier\u00a0R, Pahouja\u00a0G, Branch\u00a0J, McVary\u00a0KT (2020) The New American Urological Association Benign Prostatic Hyperplasia Clinical Guidelines: 2019 Update. Curr Urol Rep 21:32","journal-title":"Curr Urol Rep"},{"key":"2857_CR5","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1007\/s00345-020-03451-1","volume":"39","author":"D Enikeev","year":"2021","unstructured":"Enikeev\u00a0D, Morozov\u00a0A, Taratkin\u00a0M, Misrai\u00a0V, Rijo\u00a0E, Podoinitsin\u00a0A, Gabdullina\u00a0S, Herrmann\u00a0TRW (2021) Systematic review of the endoscopic enucleation of the prostate learning curve. World journal of urology 39:2427\u20132438","journal-title":"World journal of urology"},{"key":"2857_CR6","unstructured":"Enikeev\u00a0DV, Glybochko\u00a0PV, Alyaev\u00a0YG, Rapoport\u00a0LM, Enikeev\u00a0ME, Tsarichenko\u00a0DG, Sorokin\u00a0NI, Sukhanov\u00a0RB, Dimov\u00a0AM, Khamraev\u00a0OK, Davydov\u00a0DS, Taratkin\u00a0MS, Simberdeev\u00a0RR (2016) [Holmium laser enucleation of the prostate (HOLEP) for small, large and giant prostatic hyperplasia. Practice guidelines. Experience of more than 450 surgeries]. Urologiia: 63\u201369"},{"key":"2857_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-05264-y","volume":"42","author":"A Morozov","year":"2024","unstructured":"Morozov\u00a0A, Bogatova\u00a0S, Bezrukov\u00a0E, Singla\u00a0N, Teoh\u00a0JY, Spivak\u00a0L, Rivas\u00a0JG, Lusuardi\u00a0L, Gauhar\u00a0V, Somani\u00a0B, Lifshitz\u00a0D, Baniel\u00a0J, Herrmann\u00a0TRW, Enikeev\u00a0D (2024) A systematic review of robot-assisted simple prostatectomy outcomes by prostate volume. World journal of urology 42:565","journal-title":"World journal of urology"},{"key":"2857_CR8","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s00345-020-03156-5","volume":"39","author":"MA Zell","year":"2021","unstructured":"Zell\u00a0MA, Abdul-Muhsin\u00a0H, Navaratnam\u00a0A, Cumsky\u00a0J, Girardo\u00a0M, Cornella\u00a0J, Nevo\u00a0A, Cheney\u00a0S, Humphreys\u00a0MR (2021) Holmium laser enucleation of the prostate for very large benign prostatic hyperplasia (\u2265 200 cc). World journal of urology 39:129\u2013134","journal-title":"World journal of urology"},{"key":"2857_CR9","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1007\/s00345-021-03708-3","volume":"39","author":"NE Boxall","year":"2021","unstructured":"Boxall\u00a0NE, Georgiades\u00a0F, Miah\u00a0S, Dragos\u00a0L, Armitage\u00a0J, Aho\u00a0TF (2021) A call for HoLEP: AEEP for mega-prostates (\u2265 200 cc). World journal of urology 39:2347\u20132353","journal-title":"World journal of urology"},{"key":"2857_CR10","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/j.urology.2023.09.002","volume":"182","author":"JG Porto","year":"2023","unstructured":"Porto\u00a0JG, Blachman-Braun\u00a0R, Delgado\u00a0C, Zarli\u00a0M, Chen\u00a0R, Ajami\u00a0T, Marcovich\u00a0R, Shah\u00a0HN (2023) Is Holmium Laser Enucleation of the Prostate Truly Size-Independent? A Critical Evaluation at the Extreme Ends of the Spectrum. Urology 182:204\u2013210","journal-title":"Urology"},{"key":"2857_CR11","doi-asserted-by":"publisher","DOI":"10.1002\/bco2.469","volume":"6","author":"FC Maluf","year":"2025","unstructured":"Maluf\u00a0FC, Bhatia\u00a0A, Khandekar\u00a0A, Lopategui\u00a0DM, Porto\u00a0JG, Chen\u00a0RR, Daher\u00a0JC, Zarli\u00a0M, Marcovich\u00a0R, Shah\u00a0HN (2025) Safety and feasibility of En-bloc holmium laser enucleation for very large prostates (\u3009\u202f200\u202fcc) with trainee involvement. BJUI Compass 6:e469","journal-title":"BJUI Compass"},{"key":"2857_CR12","doi-asserted-by":"publisher","first-page":"218","DOI":"10.4111\/kju.2015.56.3.218","volume":"56","author":"M Kim","year":"2015","unstructured":"Kim\u00a0M, Piao\u00a0S, Lee\u00a0HE, Kim\u00a0SH, Oh\u00a0SJ (2015) Efficacy and safety of holmium laser enucleation of the prostate for extremely large prostatic adenoma in patients with benign prostatic hyperplasia. Korean J Urol 56:218\u2013226","journal-title":"Korean J Urol"},{"key":"2857_CR13","doi-asserted-by":"publisher","first-page":"169","DOI":"10.5301\/uj.5000232","volume":"84","author":"PV Glybochko","year":"2017","unstructured":"Glybochko\u00a0PV, Rapoport\u00a0LM, Enikeev\u00a0ME, Enikeev\u00a0DV (2017) Holmium laser enucleation of the prostate (HoLEP) for small, large and giant prostatic hyperplasia: tips and tricks. Urologia 84:169\u2013173","journal-title":"Urologia"},{"key":"2857_CR14","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1089\/end.2020.1218","volume":"35","author":"MA Assmus","year":"2021","unstructured":"Assmus\u00a0MA, Large\u00a0T, Lee\u00a0MS, Agarwal\u00a0DK, Rivera\u00a0ME, Krambeck\u00a0AE (2021) Same-Day Discharge Following Holmium Laser Enucleation in Patients Assessed to Have Large\u00a0Gland Prostates (\u2265 175 cc). Journal of endourology 35:1386\u20131392","journal-title":"Journal of endourology"},{"key":"2857_CR15","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1089\/end.2022.0851","volume":"37","author":"J Van der Jeugt","year":"2023","unstructured":"Van der Jeugt\u00a0J, Umari\u00a0P, Mottaran\u00a0A, Ribeiro\u00a0L, Lambert\u00a0E, Vollemaere\u00a0J, Develtere\u00a0D, Veys\u00a0R, Goossens\u00a0M, Pauwaert\u00a0K, Scarcella\u00a0S, Van Praet\u00a0C, Pauwels\u00a0E, De Groote\u00a0R, D\u2019Hondt\u00a0F, De Naeyer\u00a0G, Mottrie\u00a0A, Schatteman\u00a0P (2023) Holmium Laser Enucleation of the Prostate vs Robot-Assisted Simple Prostatectomy for Lower Urinary Tract Symptoms in Patients with Extremely Large Prostates \u2265\u202f200\u202fcc: A\u00a0Comparative Analysis. Journal of endourology 37:895\u2013902","journal-title":"Journal of endourology"},{"key":"2857_CR16","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1089\/end.2005.19.550","volume":"19","author":"WW Tinmouth","year":"2005","unstructured":"Tinmouth\u00a0WW, Habib\u00a0E, Kim\u00a0SC, Kuo\u00a0RL, Paterson\u00a0RF, Terry\u00a0CL, Elhilali\u00a0M, Lingeman\u00a0JE (2005) Change in serum prostate specific antigen concentration after holmium laser enucleation of the prostate: a marker for completeness of adenoma resection? Journal of endourology 19:550\u2013554","journal-title":"Journal of endourology"},{"key":"2857_CR17","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1089\/end.2024.0601","volume":"39","author":"MK Choudhary","year":"2025","unstructured":"Choudhary\u00a0MK, Kolanukuduru\u00a0KP, Eraky\u00a0A, Mohammed\u00a0A, Tillu\u00a0N, Sur\u00a0H, Ohayon\u00a0L, Venkatesh\u00a0A, Rangchi\u00a0A, Dovey\u00a0Z, Zaytoun\u00a0O, Buscarini\u00a0M (2025) Comparative Outcomes of En-Bloc Holmium Laser Enucleation of the Prostate and Transvesical Robot-Assisted Simple Prostatectomy for the Management of Benign Prostatic Hyperplasia: A Propensity-Matched Analysis. Journal of endourology 39:57\u201363","journal-title":"Journal of endourology"},{"key":"2857_CR18","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1159\/000530627","volume":"107","author":"FO Hartung","year":"2023","unstructured":"Hartung\u00a0FO, Kowalewski\u00a0KF, Morina\u00a0F, Egen\u00a0L, Neuberger\u00a0M, Gruene\u00a0B, Wenk\u00a0M, Kriegmair\u00a0MC, Nuhn\u00a0P, Patroi\u00a0P, Westhoff\u00a0N, Honeck\u00a0P, Rassweiler-Seyfried\u00a0MC, Michel\u00a0MS, Herrmann\u00a0J (2023) Perioperative Outcome of Thulium Laser Enucleation of the Prostate versus Robot-Assisted Simple Prostatectomy: A Propensity Score-Matched Analysis. Urologia internationalis 107:678\u2013683","journal-title":"Urologia internationalis"},{"key":"2857_CR19","doi-asserted-by":"publisher","first-page":"1018","DOI":"10.1089\/end.2021.0788","volume":"36","author":"KF Kowalewski","year":"2022","unstructured":"Kowalewski\u00a0KF, Hartung\u00a0FO, von Hardenberg\u00a0J, Haney\u00a0CM, Kriegmair\u00a0MC, Nuhn\u00a0P, Patroi\u00a0P, Westhoff\u00a0N, Honeck\u00a0P, Herrmann\u00a0TRW, Michel\u00a0MS, Herrmann\u00a0J (2022) Robot-Assisted Simple Prostatectomy vs Endoscopic Enucleation of the Prostate: A Systematic Review and Meta-Analysis of Comparative Trials. Journal of endourology 36:1018\u20131028","journal-title":"Journal of endourology"},{"key":"2857_CR20","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1089\/end.2009.0147","volume":"24","author":"AE Krambeck","year":"2010","unstructured":"Krambeck\u00a0AE, Handa\u00a0SE, Lingeman\u00a0JE (2010) Holmium laser enucleation of the prostate for prostates larger than 175 grams. Journal of endourology 24:433\u2013437","journal-title":"Journal of endourology"},{"key":"2857_CR21","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-024-04959-6","volume":"42","author":"P Julieb\u00f8-Jones","year":"2024","unstructured":"Julieb\u00f8-Jones\u00a0P, Gauhar\u00a0V, Castellani\u00a0D, Fong\u00a0KY, Sofer\u00a0M, Zawadzki\u00a0M, Gadzhiev\u00a0N, Pirola\u00a0GM, Mahajan\u00a0AD, Maheshwari\u00a0PN, Malkhasyan\u00a0V, Biligere\u00a0S, G\u00f6kce\u00a0M, Cormio\u00a0L, Enikeev\u00a0D, G\u00f3mez Sancha\u00a0F, Herrmann\u00a0TRW, Somani\u00a0BK (2024) Real world propensity score matched analysis evaluating the influence of en-bloc vs. non en-bloc techniques, energy and instrumentation on enucleation outcomes for large and very large prostates. World journal of urology 42:299","journal-title":"World journal of urology"},{"key":"2857_CR22","doi-asserted-by":"crossref","unstructured":"Heiman\u00a0J, Krambeck\u00a0A, Agarwal\u00a0D, Lingeman\u00a0J, Rivera\u00a0M, Large\u00a0T (2020)Temporary Perineal Urethrostomy During Holmium Laser Enucleation of the Prostate (HoLEP). International Journal of Surgical Case Reports: 1\u20114","DOI":"10.31487\/j.IJSCR.2020.02.04"},{"key":"2857_CR23","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1055\/a-2307-3887","volume":"55","author":"FO Hartung","year":"2024","unstructured":"Hartung\u00a0FO, Gruene\u00a0B, Becker\u00a0B, Rassweiler-Seyfried\u00a0MC, Miernik\u00a0A, Lusuardi\u00a0L, Herrmann\u00a0TR, Lehrich\u00a0K, Netsch\u00a0C, Herrmann\u00a0J (2024) Prostate Surgery for Benign Prostatic Syndrome \u3009\u202f200\u202fml: Endoscopic, Robotic, or Open Approach. Aktuelle Urologie 55:213\u2013218","journal-title":"Aktuelle Urologie"},{"key":"2857_CR24","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1159\/000528721","volume":"107","author":"S Morishige","year":"2023","unstructured":"Morishige\u00a0S, Ohyama\u00a0T, Fujita\u00a0N, Kameda\u00a0M, Yonekura\u00a0Y, Endo\u00a0F, Abe\u00a0S (2023) Risk Factors for Intraoperative Hypothermia during Holmium Laser Enucleation of the Prostate. Urologia internationalis 107:672\u2013677","journal-title":"Urologia internationalis"}],"container-title":["Die Urologie"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00120-026-02857-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00120-026-02857-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00120-026-02857-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:09:49Z","timestamp":1791371389000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00120-026-02857-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,5]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["2857"],"URL":"https:\/\/doi.org\/10.1007\/s00120-026-02857-w","relation":{},"ISSN":["2731-7064","2731-7072"],"issn-type":[{"value":"2731-7064","type":"print"},{"value":"2731-7072","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,5]]},"assertion":[{"value":"21 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"J.\u00a0Herrmann macht folgende Angabe: Boston Scientific (Proctor, Consultant).  C. Netsch macht folgende Angabe:  Richard Wolf (Proctor, Consultant). F.O.\u00a0Hartung, L.\u00a0Lusuardi und T.R.W.\u00a0Herrmann geben an, dass kein Interessenkonflikt besteht.","order":1,"name":"Ethics","label":"Interessenkonflikt","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}