{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:11:01Z","timestamp":1790259061874,"version":"4.1.0"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2007,4,11]],"date-time":"2007-04-11T00:00:00Z","timestamp":1176249600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2007,5,3]]},"DOI":"10.1007\/s00125-007-0628-x","type":"journal-article","created":{"date-parts":[[2007,4,18]],"date-time":"2007-04-18T12:48:02Z","timestamp":1176900482000},"page":"1335-1344","source":"Crossref","is-referenced-by-count":75,"title":["Enhanced activity of the myocardial Na+\/H+ exchanger contributes to left ventricular hypertrophy in the Goto\u2013Kakizaki rat model of type 2 diabetes: critical role of Akt"],"prefix":"10.1007","volume":"50","author":[{"given":"A.","family":"Darmellah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Baetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Prunier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tamareille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"R\u00fccker-Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Feuvray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2007,4,11]]},"reference":[{"key":"628_CR1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/clc.4960180604","volume":"18","author":"A Shehadeh","year":"1995","unstructured":"Shehadeh A, Regan TJ (1995) Cardiac consequences of diabetes mellitus. Clin Cardiol 18:301\u2013305","journal-title":"Clin Cardiol"},{"key":"628_CR2","doi-asserted-by":"crossref","first-page":"2271","DOI":"10.1161\/01.CIR.101.19.2271","volume":"101","author":"RB Devereux","year":"2000","unstructured":"Devereux RB, Roman MJ, Paranicas M et al (2000) Impact of diabetes on cardiac structure and function: the strong heart study. Circulation 101:2271\u20132276","journal-title":"Circulation"},{"key":"628_CR3","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1016\/S0140-6736(02)08358-7","volume":"359","author":"A Struthers","year":"2002","unstructured":"Struthers A, Morris A (2002) Screening for and treating left-ventricular abnormalities in diabetes mellitus: a new way of reducing cardiac deaths. Lancet 359:1430\u20131432","journal-title":"Lancet"},{"key":"628_CR4","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1161\/01.RES.87.12.1123","volume":"87","author":"A Frustaci","year":"2000","unstructured":"Frustaci A, Kajstura J, Chimenti C et al (2000) Myocardial cell death in human diabetes. Circ Res 87:1123\u20131132","journal-title":"Circ Res"},{"key":"628_CR5","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1139\/y97-027","volume":"75","author":"GN Pierce","year":"1997","unstructured":"Pierce GN, Maddaford TG, Russell JC (1997) Cardiovascular dysfunction in insulin-dependent and non-insulin-dependent animal models of diabetes mellitus. Can J Physiol Pharmacol 75:343\u2013350","journal-title":"Can J Physiol Pharmacol"},{"key":"628_CR6","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.2337\/diabetes.53.12.3201","volume":"53","author":"DD Belke","year":"2004","unstructured":"Belke DD, Swanson EA, Dillmann WH (2004) Decreased sarcoplasmic reticulum activity and contractility in diabetic db\/db mouse heart. Diabetes 53:3201\u20133208","journal-title":"Diabetes"},{"key":"628_CR7","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.yjmcc.2004.05.014","volume":"37","author":"M Desrois","year":"2004","unstructured":"Desrois M, Sidell RJ, Gauguier D, Davey CL, Radda GK, Clarke K (2004) Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart. J Mol Cell Cardiol 37:547\u2013555","journal-title":"J Mol Cell Cardiol"},{"key":"628_CR8","doi-asserted-by":"crossref","first-page":"486","DOI":"10.2337\/diab.40.4.486","volume":"40","author":"B Portha","year":"1991","unstructured":"Portha B, Serradas P, Bailbe D, Suzuki K, Goto Y, Giroix MH (1991) Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes. Diabetes 40:486\u2013491","journal-title":"Diabetes"},{"key":"628_CR9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/ng0196-38","volume":"12","author":"D Gauguier","year":"1996","unstructured":"Gauguier D, Froguel P, Parent V et al (1996) Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat. Nat Genet 12:38\u201343","journal-title":"Nat Genet"},{"key":"628_CR10","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1161\/01.RES.85.9.777","volume":"85","author":"M Karmazyn","year":"1999","unstructured":"Karmazyn M, Gan XT, Humphreys RA, Yoshida H, Kusumoto K (1999) The myocardial Na+\u2013H+ exchange: structure, regulation, and its role in heart disease. Circ Res 85:777\u2013786","journal-title":"Circ Res"},{"key":"628_CR11","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/cvr\/24.11.873","volume":"24","author":"N Khandoudi","year":"1990","unstructured":"Khandoudi N, Bernard M, Cozzone P, Feuvray D (1990) Intracellular pH and role of Na+\/H+ exchange during ischaemia and reperfusion of normal and diabetic rat hearts. Cardiovasc Res 24:873\u2013878","journal-title":"Cardiovasc Res"},{"key":"628_CR12","doi-asserted-by":"crossref","first-page":"196","DOI":"10.2337\/diab.44.2.196","volume":"44","author":"N Khandoudi","year":"1995","unstructured":"Khandoudi N, Bernard M, Cozzone P, Feuvray D (1995) Mechanisms of intracellular pH regulation during postischemic reperfusion of diabetic rat hearts. Diabetes 44:196\u2013202","journal-title":"Diabetes"},{"key":"628_CR13","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1161\/01.RES.80.2.253","volume":"80","author":"K Prigent Le","year":"1997","unstructured":"Le Prigent K, Lagadic-Gossmann D, Feuvray D (1997) Modulation by pH0 and intracellular Ca2+ of Na+\u2013H+ exchange in diabetic rat isolated ventricular myocytes. Circ Res 80:253\u2013260","journal-title":"Circ Res"},{"key":"628_CR14","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1161\/01.CIR.101.23.2749","volume":"101","author":"H Stromer","year":"2000","unstructured":"Stromer H, de Groot MC, Horn M et al (2000) Na+\/H+ exchange inhibition with HOE642 improves postischemic recovery due to attenuation of Ca2+ overload and prolonged acidosis on reperfusion. Circulation 101:2749\u20132755","journal-title":"Circulation"},{"key":"628_CR15","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0022-2828(08)80063-6","volume":"27","author":"S Takewaki","year":"1995","unstructured":"Takewaki S, Kuro-o M, Hiroi Y et al (1995) Activation of Na+\u2013H+ antiporter (NHE\u20131), gene expression during growth, hypertrophy and proliferation of the rabbit cardiovascular system. J Mol Cell Cardiol 27:729\u2013742","journal-title":"J Mol Cell Cardiol"},{"key":"628_CR16","first-page":"H738","volume":"280","author":"K Kusumoto","year":"2001","unstructured":"Kusumoto K, Haist JV, Karmazyn M (2001) Na+\/H+ exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats. Am J Physiol 280:H738\u2013H745","journal-title":"Am J Physiol"},{"key":"628_CR17","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1161\/01.RES.0000014966.97486.C0","volume":"90","author":"S Engelhardt","year":"2002","unstructured":"Engelhardt S, Hein L, Keller U, Kl\u00e4mbt K, Lohse MJ (2002) Inhibition of Na+\u2013H+ exchange prevents hypertrophy, fibrosis and heart failure in \u00df1-adrenergic receptor transgenic mice. Circ Res 90:814\u2013819","journal-title":"Circ Res"},{"key":"628_CR18","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00210-003-0808-2","volume":"368","author":"WJ Linz","year":"2003","unstructured":"Linz WJ, Busch AE (2003) NHE-1 inhibition: from protection during acute ischaemia\/reperfusion to prevention\/reversal of myocardial remodelling. Naunyn Schmiedebergs Arch Pharmacol 368:239\u2013246","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"628_CR19","doi-asserted-by":"crossref","first-page":"1898","DOI":"10.1161\/01.CIR.0000124230.60028.42","volume":"109","author":"Y Chen","year":"2004","unstructured":"Chen Y, Escoubet B, Prunier F et al (2004) Constitutive cardiac overexpression of sarcoplasmic\/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias. Circulation 109:1898\u20131903","journal-title":"Circulation"},{"key":"628_CR20","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0008-6363(02)00338-3","volume":"55","author":"C R\u00fccker-Martin","year":"2002","unstructured":"R\u00fccker-Martin C, Pecker F, Godreau D, Hatem SN (2002) Dedifferentiation of atrial myocytes during atrial fibrillation: role of fibroblast proliferation in vitro. Cardiovasc Res 55:38\u201352","journal-title":"Cardiovasc Res"},{"key":"628_CR21","first-page":"H2102","volume":"283","author":"D Baetz","year":"2002","unstructured":"Baetz D, Haworth RS, Avkiran M, Feuvray D (2002) The ERK pathway regulates Na+\u2013HCO3 \u2212 cotransport activity in adult rat cardiomyocytes. Am J Physiol 283:H2102\u2013H2109","journal-title":"Am J Physiol"},{"key":"628_CR22","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1016\/S0006-3495(96)79711-4","volume":"70","author":"H Satoh","year":"1996","unstructured":"Satoh H, Delbridge LM, Blatter LA, Bers DM (1996) Surface:volume relationship in cardiac myocytes studied with confocal microscopy and membrane capacitance measurements: species-dependence and developmental effects. Biophys J 70:1494\u20131504","journal-title":"Biophys J"},{"key":"628_CR23","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1006\/jmcc.2000.1151","volume":"32","author":"S Chattou","year":"2000","unstructured":"Chattou S, Coulombe A, Diacono J, Le Grand B, John G, Feuvray D (2000) Slowly inactivating component of sodium current in ventricular myocytes is decreased by diabetes and partially inhibited by known Na+\u2013H+ exchange blockers. J Mol Cell Cardiol 32:1181\u20131192","journal-title":"J Mol Cell Cardiol"},{"key":"628_CR24","first-page":"H1529","volume":"270","author":"D Lagadic-Gossmann","year":"1996","unstructured":"Lagadic-Gossmann D, Buckler KJ, Le Prigent K, Feuvray D (1996) Altered Ca2+ handling in ventricular myocytes isolated from diabetic rats. Am J Physiol 270:H1529\u2013H1537","journal-title":"Am J Physiol"},{"key":"628_CR25","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1172\/JCI118960","volume":"98","author":"J Wang","year":"1996","unstructured":"Wang J, Schwinger RH, Frank K et al (1996) Regional expression of sodium pump subunits isoforms and Na+\u2013Ca++ exchanger in the human heart. J Clin Invest 98:1650\u20131658","journal-title":"J Clin Invest"},{"key":"628_CR26","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.yjmcc.2005.03.014","volume":"39","author":"LE Wold","year":"2005","unstructured":"Wold LE, Dutta K, Mason MM et al (2005) Impaired SERCA function contributes to cardiomyocyte dysfunction in insulin-resistant rats. J Mol Cell Cardiol 39:297\u2013307","journal-title":"J Mol Cell Cardiol"},{"key":"628_CR27","doi-asserted-by":"crossref","first-page":"C772","DOI":"10.1152\/ajpcell.00086.2005","volume":"291","author":"Z Vasanji","year":"2006","unstructured":"Vasanji Z, Cantor EJ, Juric D, Moyen M, Netticadan T (2006) Alterations in cardiac contractile performance and sarcoplasmic reticulum function in sucrose-fed rats is associated with insulin resistance. Am J Physiol Cell Physiol 291:C772\u2013C780","journal-title":"Am J Physiol Cell Physiol"},{"key":"628_CR28","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1136\/jmg.36.7.542","volume":"36","author":"P Richard","year":"1999","unstructured":"Richard P, Isnard R, Carrier L et al (1999) Double heterozygosity for mutations in the \u03b2-myosin heavy chain and in the cardiac myosin binding protein C genes in a family with hypertrophic cardiomyopathy. J Med Genet 36:542\u2013545","journal-title":"J Med Genet"},{"key":"628_CR29","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1161\/01.RES.88.4.376","volume":"88","author":"NG Perez","year":"2001","unstructured":"Perez NG, de Hurtado MC, Cingolani HE (2001) Reverse mode of the Na+\u2013Ca2+ exchange after myocardial stretch: underlying mechanism of the slow force response. Circ Res 88:376\u2013382","journal-title":"Circ Res"},{"key":"628_CR30","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1161\/01.RES.65.4.1045","volume":"65","author":"M Tani","year":"1989","unstructured":"Tani M, Neely JR (1989) Role of intracellular Na+ in Ca2+ overload and depressed recovery of ventricular function of reperfused ischemic rat hearts. Possible involvement of H+\u2013Na+ and Na+\u2013Ca2+ exchange. Circ Res 65:1045\u20131056","journal-title":"Circ Res"},{"key":"628_CR31","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0014-5793(02)02867-3","volume":"521","author":"K Maly","year":"2002","unstructured":"Maly K, Strese K, Kampfer S et al (2002) Critical role of protein kinase C \u03b1 and calcium in growth factor induced activation of the Na+\/H+ exchanger NHE1. FEBS Lett 521:205\u2013210","journal-title":"FEBS Lett"},{"key":"628_CR32","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.cardiores.2004.04.032","volume":"63","author":"R Schreckenberg","year":"2004","unstructured":"Schreckenberg R, Taimor G, Piper HM, Schl\u00fcter K-D (2004) Inhibition of Ca2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. Cardiovasc Res 63:553\u2013560","journal-title":"Cardiovasc Res"},{"key":"628_CR33","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1161\/01.RES.86.2.214","volume":"86","author":"AK Snabaitis","year":"2000","unstructured":"Snabaitis AK, Yokoyama H, Avkiran M (2000) Roles of mitogen-activated protein kinases and protein kinase C in \u03b11A-adrenoceptor-mediated stimulation of the sarcolemmal Na+\u2013H+ exchanger. Circ Res 86:214\u2013220","journal-title":"Circ Res"},{"key":"628_CR34","doi-asserted-by":"crossref","first-page":"22985","DOI":"10.1074\/jbc.274.33.22985","volume":"274","author":"AN Moor","year":"1999","unstructured":"Moor AN, Fliegel L (1999) Protein-kinase-mediated regulation of the Na+\/H+ exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways. J Biol Chem 274:22985\u201322992","journal-title":"J Biol Chem"},{"key":"628_CR35","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1161\/01.RES.0000044380.54893.4B","volume":"91","author":"C Depr\u00e9","year":"2002","unstructured":"Depr\u00e9 C, Hase M, Gaussin V et al (2002) H11 kinase is a novel mediator of myocardial hypertrophy in vivo. Circ Res 91:1007\u20131014","journal-title":"Circ Res"},{"key":"628_CR36","doi-asserted-by":"crossref","first-page":"26280","DOI":"10.1074\/jbc.M400814200","volume":"279","author":"KL Wu","year":"2004","unstructured":"Wu KL, Khan S, Lakhe-Reddy S et al (2004) The NHE1 Na+\/H+ exchanger recruits ezrin\/radixin\/moesin proteins to regulate Akt-dependent cell survival. J Biol Chem 279:26280\u201326286","journal-title":"J Biol Chem"},{"key":"628_CR37","doi-asserted-by":"crossref","first-page":"4394","DOI":"10.1158\/0008-5472.CAN-04-0343","volume":"64","author":"L Yang","year":"2004","unstructured":"Yang L, Dan HC, Sun M et al (2004) Akt\/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 64:4394\u20134399","journal-title":"Cancer Res"},{"key":"628_CR38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1074\/jbc.275.1.1","volume":"275","author":"L Counillon","year":"2000","unstructured":"Counillon L, Pouyss\u00e9gur J (2000) The expanding family of eukaryotic Na+\/H+ exchangers. J Biol Chem 275:1\u20134","journal-title":"J Biol Chem"},{"key":"628_CR39","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1042\/bj20020228","volume":"364","author":"A Hudmon","year":"2002","unstructured":"Hudmon A, Schulman H (2002) Structure-function of the multifunctional Ca2+\/calmodulin-dependent protein kinase II. Biochem J 364:593\u2013611","journal-title":"Biochem J"},{"key":"628_CR40","doi-asserted-by":"crossref","first-page":"45101","DOI":"10.1074\/jbc.M305355200","volume":"278","author":"M Illario","year":"2003","unstructured":"Illario M, Cavallo AL, Bayer U et al (2003) Calcium\/calmodulin-dependent protein kinase II binds to raf-1 and modulates integrin-stimulated ERK activation. J Biol Chem 278:45101\u201345108","journal-title":"J Biol Chem"},{"key":"628_CR41","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1074\/jbc.M304907200","volume":"279","author":"YV Mukhin","year":"2004","unstructured":"Mukhin YV, Garnovskaya MN, Ullian ME, Raymond JR (2004) ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells. J Biol Chem 279:1845\u20131852","journal-title":"J Biol Chem"},{"key":"628_CR42","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1161\/01.RES.87.12.1133","volume":"87","author":"K Jandeleit-Dahm","year":"2000","unstructured":"Jandeleit\u2013Dahm K, Hannan KM, Farrelly CA et al (2000) Diabetes\u2013induced vascular hypertrophy is accompanied by activation of Na+\u2013H+ exchange and prevented by Na+\u2013H+ exchange inhibition. Circ Res 87:1133\u20131140","journal-title":"Circ Res"},{"key":"628_CR43","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/S0008-6363(01)00544-2","volume":"53","author":"MC Camilion de Hurtado","year":"2002","unstructured":"Camilion de Hurtado MC, Portiansky EL, Perez NG, Rebolledo OR, Cingolani HE (2002) Regression of cardiomyocyte hypertrophy in SHR following chronic inhibition of the Na+\/H+ exchanger. Cardiovasc Res 53:862\u2013868","journal-title":"Cardiovasc Res"},{"key":"628_CR44","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1161\/CIRCULATIONAHA.105.542209","volume":"112","author":"A Kilic","year":"2005","unstructured":"Kilic A, Velic A, De Windt LJ et al (2005) Enhanced activity of the myocardial Na+\/H+ exchanger NHE-1 contributes to cardiac remodeling in atrial natriuretic peptide receptor-deficient mice. Circulation 112:2307\u20132317","journal-title":"Circulation"},{"key":"628_CR45","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1002\/dmrr.623","volume":"22","author":"P R\u00f6sen","year":"2006","unstructured":"R\u00f6sen P, Wiernsperger NF (2006) Metformin delays the manifestation of diabetes and vascular dysfunction in Goto\u2013Kakizaki rats by reduction of mitochondrial oxidative stress. Diabetes Metab Res Rev 22:323\u2013330","journal-title":"Diabetes Metab Res Rev"},{"key":"628_CR46","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0008-6363(97)00044-8","volume":"34","author":"D Feuvray","year":"1997","unstructured":"Feuvray D (1997) The regulation of intracellular pH in the diabetic myocardium. Cardiovasc Res 34:48\u201354","journal-title":"Cardiovasc Res"},{"key":"628_CR47","first-page":"19","volume":"40","author":"I Iltis","year":"2005","unstructured":"Iltis I, Kober F, Desrois M et al (2005) Defective myocardial blood flow and altered function of the left ventricle in type 2 diabetic rats. Invest Radiol 40:19\u201326","journal-title":"Invest Radiol"},{"key":"628_CR48","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1007\/s00125-005-0091-5","volume":"49","author":"R Anzawa","year":"2006","unstructured":"Anzawa R, Bernard M, Tamareille S et al (2006) Intracellular sodium increase and susceptibility to ischaemia in hearts from type 2 diabetic db\/db mice. Diabetologia 49:598\u2013606","journal-title":"Diabetologia"},{"key":"628_CR49","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1161\/01.CIR.91.3.635","volume":"91","author":"PJ Nahser","year":"1995","unstructured":"Nahser PJ, Brown RE, Okarsson H, Winniford MD, Rossen JD (1995) Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation 91:635\u2013640","journal-title":"Circulation"},{"key":"628_CR50","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.2337\/diabetes.50.5.1180","volume":"50","author":"A Nitenberg","year":"2001","unstructured":"Nitenberg A, Ledoux S, Valensi P, Sachs R, Attali J-R, Antony I (2001) Impairment of coronary microvascular dilation in response to cold pressor-induced sympathetic stimulation in type 2 diabetic patients with abnormal stress thallium imaging. Diabetes 50:1181\u20131185","journal-title":"Diabetes"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-007-0628-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00125-007-0628-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-007-0628-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T14:19:35Z","timestamp":1683814775000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00125-007-0628-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4,11]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,5,3]]}},"alternative-id":["628"],"URL":"https:\/\/doi.org\/10.1007\/s00125-007-0628-x","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4,11]]}}}