{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:23:38Z","timestamp":1790421818745,"version":"4.1.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1007\/s00125-012-2743-6","type":"journal-article","created":{"date-parts":[[2012,10,9]],"date-time":"2012-10-09T03:28:28Z","timestamp":1349753308000},"page":"82-91","source":"Crossref","is-referenced-by-count":75,"title":["Association of physical activity with all-cause mortality and incident and prevalent cardiovascular disease among patients with type 1 diabetes: the EURODIAB Prospective Complications Study"],"prefix":"10.1007","volume":"56","author":[{"given":"S. M. A. J.","family":"Tielemans","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. S.","family":"Soedamah-Muthu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"De Neve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Toeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Chaturvedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Stamatakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,10,10]]},"reference":[{"issue":"Suppl 1","key":"2743_CR1","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.diabres.2007.01.019","volume":"76","author":"N Chaturvedi","year":"2007","unstructured":"Chaturvedi N (2007) The burden of diabetes and its complications: trends and implications for intervention. Diabetes Res Clin Pract 76(Suppl 1):S3\u2013S12","journal-title":"Diabetes Res Clin Pract"},{"issue":"Suppl 2","key":"2743_CR2","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1007\/PL00002934","volume":"44","author":"NJ Morrish","year":"2001","unstructured":"Morrish NJ, Wang SL, Stevens LK, Fuller JH, Keen H (2001) Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 44(Suppl 2):S14\u2013S21","journal-title":"Diabetologia"},{"key":"2743_CR3","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1503\/cmaj.051351","volume":"174","author":"DE Warburton","year":"2006","unstructured":"Warburton DE, Nicol CW, Bredin SS (2006) Health benefits of physical activity: the evidence. Can Med Assoc J 174:801\u2013809","journal-title":"Can Med Assoc J"},{"key":"2743_CR4","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.2337\/diacare.27.10.2518","volume":"27","author":"RJ Sigal","year":"2004","unstructured":"Sigal RJ, Kenny GP, Wasserman DH, Castaneda-Sceppa C (2004) Physical activity\/exercise and type 2 diabetes. Diabetes Care 27:2518\u20132539","journal-title":"Diabetes Care"},{"key":"2743_CR5","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1001\/jama.288.13.1622","volume":"288","author":"KJ Stewart","year":"2002","unstructured":"Stewart KJ (2002) Exercise training and the cardiovascular consequences of type 2 diabetes and hypertension: plausible mechanisms for improving cardiovascular health. JAMA 288:1622\u20131631","journal-title":"JAMA"},{"key":"2743_CR6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0140-6736(01)05415-0","volume":"358","author":"MA Atkinson","year":"2001","unstructured":"Atkinson MA, Eisenbarth GS (2001) Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 358:221\u2013229","journal-title":"Lancet"},{"key":"2743_CR7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0140-6736(06)68341-4","volume":"367","author":"D Daneman","year":"2006","unstructured":"Daneman D (2006) Type 1 diabetes. Lancet 367:847\u2013858","journal-title":"Lancet"},{"key":"2743_CR8","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/oxfordjournals.aje.a116604","volume":"137","author":"CS Moy","year":"1993","unstructured":"Moy CS, Songer TJ, LaPorte RE et al (1993) Insulin-dependent diabetes mellitus, physical activity, and death. Am J Epidemiol 137:74\u201381","journal-title":"Am J Epidemiol"},{"key":"2743_CR9","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1016\/0895-4356(91)90153-Z","volume":"44","author":"AM Kriska","year":"1991","unstructured":"Kriska AM, LaPorte RE, Patrick SL, Kuller LH, Orchard TJ (1991) The association of physical activity and diabetic complications in individuals with insulin-dependent diabetes mellitus: the Epidemiology of Diabetes Complications Study\u2013VII. J Clin Epidemiol 44:1207\u20131214","journal-title":"J Clin Epidemiol"},{"key":"2743_CR10","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1542\/peds.78.6.1027","volume":"78","author":"RE LaPorte","year":"1986","unstructured":"LaPorte RE, Dorman JS, Tajima N et al (1986) Pittsburgh Insulin-Dependent Diabetes Mellitus Morbidity and Mortality Study: physical activity and diabetic complications. Pediatrics 78:1027\u20131033","journal-title":"Pediatrics"},{"key":"2743_CR11","doi-asserted-by":"crossref","first-page":"230","DOI":"10.2337\/dc07-1238","volume":"31","author":"J Waden","year":"2008","unstructured":"Waden J, Forsblom C, Thorn LM et al (2008) Physical activity and diabetes complications in patients with type 1 diabetes: the Finnish Diabetic Nephropathy (FinnDiane) Study. Diabetes Care 31:230\u2013232","journal-title":"Diabetes Care"},{"key":"2743_CR12","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1007\/s00125-011-2403-2","volume":"55","author":"M Chimen","year":"2012","unstructured":"Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P (2012) What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review. Diabetologia 55:542\u2013551","journal-title":"Diabetologia"},{"key":"2743_CR13","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1007\/BF00398055","volume":"37","author":"The EURODIAB IDDM Complications Study","year":"1994","unstructured":"The EURODIAB IDDM Complications Study (1994) Microvascular and acute complications in IDDM patients: the EURODIAB IDDM Complications Study. Diabetologia 37:278\u2013285","journal-title":"Diabetologia"},{"key":"2743_CR14","doi-asserted-by":"crossref","first-page":"284","DOI":"10.2337\/diacare.24.2.284","volume":"24","author":"N Chaturvedi","year":"2001","unstructured":"Chaturvedi N, Sjoelie AK, Porta M et al (2001) Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes. Diabetes Care 24:284\u2013289","journal-title":"Diabetes Care"},{"key":"2743_CR15","doi-asserted-by":"crossref","first-page":"689","DOI":"10.2337\/diacare.19.7.689","volume":"19","author":"VA Koivisto","year":"1996","unstructured":"Koivisto VA, Stevens LK, Mattock M et al (1996) Cardiovascular disease and its risk factors in IDDM in Europe. EURODIAB IDDM Complications Study Group. Diabetes Care 19:689\u2013697","journal-title":"Diabetes Care"},{"key":"2743_CR16","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1007\/s00125-010-1785-x","volume":"53","author":"P Demakakos","year":"2010","unstructured":"Demakakos P, Hamer M, Stamatakis E, Steptoe A (2010) Low-intensity physical activity is associated with reduced risk of incident type 2 diabetes in older adults: evidence from the English Longitudinal Study of Ageing. Diabetologia 53:1877\u20131885","journal-title":"Diabetologia"},{"key":"2743_CR17","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.psyneuen.2009.02.004","volume":"34","author":"M Hamer","year":"2009","unstructured":"Hamer M, Molloy GJ, de Oliveira C, Demakakos P (2009) Leisure time physical activity, risk of depressive symptoms, and inflammatory mediators: the English Longitudinal Study of Ageing. Psychoneuroendocrinology 34:1050\u20131055","journal-title":"Psychoneuroendocrinology"},{"key":"2743_CR18","doi-asserted-by":"crossref","first-page":"S498","DOI":"10.1097\/00005768-200009001-00009","volume":"32","author":"BE Ainsworth","year":"2000","unstructured":"Ainsworth BE, Haskell WL, Whitt MC et al (2000) Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 32:S498\u2013S504","journal-title":"Med Sci Sports Exerc"},{"key":"2743_CR19","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","volume":"42","author":"AV Chobanian","year":"2003","unstructured":"Chobanian AV, Bakris GL, Black HR et al (2003) Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42:1206\u20131252","journal-title":"Hypertension"},{"key":"2743_CR20","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1093\/clinchem\/19.5.476","volume":"19","author":"G Bucolo","year":"1973","unstructured":"Bucolo G, David H (1973) Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 19:476\u2013482","journal-title":"Clin Chem"},{"key":"2743_CR21","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1093\/clinchem\/29.6.1075","volume":"29","author":"J Siedel","year":"1983","unstructured":"Siedel J, Hagele EO, Ziegenhorn J, Wahlefeld AW (1983) Reagent for the enzymatic determination of serum total cholesterol with improved lipolytic efficiency. Clin Chem 29:1075\u20131080","journal-title":"Clin Chem"},{"key":"2743_CR22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0022-2275(20)41577-9","volume":"19","author":"GR Warnick","year":"1978","unstructured":"Warnick GR, Albers JJ (1978) A comprehensive evaluation of the heparin-manganese precipitation procedure for estimating high density lipoprotein cholesterol. J Lipid Res 19:65\u201376","journal-title":"J Lipid Res"},{"key":"2743_CR23","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","author":"WT Friedewald","year":"1972","unstructured":"Friedewald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499\u2013502","journal-title":"Clin Chem"},{"key":"2743_CR24","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/clinchem\/39.4.663","volume":"39","author":"WG John","year":"1993","unstructured":"John WG, Gray MR, Bates DL, Beacham JL (1993) Enzyme immunoassay\u2014a new technique for estimating hemoglobin A1c. Clin Chem 39:663\u2013666","journal-title":"Clin Chem"},{"key":"2743_CR25","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1046\/j.1523-1755.2001.00789.x","volume":"60","author":"N Chaturvedi","year":"2001","unstructured":"Chaturvedi N, Bandinelli S, Mangili R, Penno G, Rottiers RE, Fuller JH (2001) Microalbuminuria in type 1 diabetes: rates, risk factors and glycemic threshold. Kidney Int 60:219\u2013227","journal-title":"Kidney Int"},{"key":"2743_CR26","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.2337\/dc10-0953","volume":"33","author":"R Hanas","year":"2010","unstructured":"Hanas R, John G, International HBA Consensus Committee (2010) 2010 consensus statement on the worldwide standardization of the hemoglobin A1C measurement. Diabetes Care 33:1903\u20131904","journal-title":"Diabetes Care"},{"key":"2743_CR27","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1373\/clinchem.2003.024802","volume":"50","author":"W Hoelzel","year":"2004","unstructured":"Hoelzel W, Weykamp C, Jeppsson JO et al (2004) IFCC reference system for measurement of hemoglobin A1c in human blood and the national standardization schemes in the United States, Japan, and Sweden: a method-comparison study. Clin Chem 50:166\u2013174","journal-title":"Clin Chem"},{"key":"2743_CR28","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1007\/BF00403912","volume":"39","author":"M Toeller","year":"1996","unstructured":"Toeller M, Klischan A, Heitkamp G et al (1996) Nutritional intake of 2868 IDDM patients from 30 centres in Europe. EURODIAB IDDM Complications Study Group. Diabetologia 39:929\u2013939","journal-title":"Diabetologia"},{"key":"2743_CR29","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0939-4753(04)80028-0","volume":"14","author":"JI Mann","year":"2004","unstructured":"Mann JI, de Leeuw I, Hermansen K et al (2004) Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus. Nutr Metab Cardiovasc Dis 14:373\u2013394","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"2743_CR30","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/BF00410281","volume":"38","author":"SJ Aldington","year":"1995","unstructured":"Aldington SJ, Kohner EM, Meuer S, Klein R, Sjolie AK (1995) Methodology for retinal photography and assessment of diabetic retinopathy: the EURODIAB IDDM complications study. Diabetologia 38:437\u2013444","journal-title":"Diabetologia"},{"key":"2743_CR31","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1136\/jcp.40.4.465","volume":"40","author":"EM Kearney","year":"1987","unstructured":"Kearney EM, Mount JN, Watts GF, Slavin BM, Kind PR (1987) Simple immunoturbidimetric method for determining urinary albumin at low concentrations using Cobas-Bio centrifugal analyser. J Clin Pathol 40:465\u2013468","journal-title":"J Clin Pathol"},{"key":"2743_CR32","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1212\/WNL.46.5.1470","volume":"46","author":"The Consensus Committee of the American Autonomic Society and the American Academy of Neurology","year":"1996","unstructured":"The Consensus Committee of the American Autonomic Society and the American Academy of Neurology (1996) Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy. Neurology 46:1470","journal-title":"Neurology"},{"key":"2743_CR33","volume-title":"The Minnesota code manual of electrocardiographic findings","author":"RJ Prineas","year":"1982","unstructured":"Prineas RJ, Crow RS, Blackburn H (1982) The Minnesota code manual of electrocardiographic findings. John Wright-PSG, Boston"},{"key":"2743_CR34","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.2337\/dc08-0107","volume":"31","author":"SS Soedamah-Muthu","year":"2008","unstructured":"Soedamah-Muthu SS, Chaturvedi N, Witte DR, Stevens LK, Porta M, Fuller JH (2008) Relationship between risk factors and mortality in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study (PCS). Diabetes Care 31:1360\u20131366","journal-title":"Diabetes Care"},{"key":"2743_CR35","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.jclinepi.2006.06.013","volume":"60","author":"TC Smith","year":"2007","unstructured":"Smith TC, Wingard DL, Smith B, Kritz-Silverstein D, Barrett-Connor E (2007) Walking decreased risk of cardiovascular disease mortality in older adults with diabetes. J Clin Epidemiol 60:309\u2013317","journal-title":"J Clin Epidemiol"},{"key":"2743_CR36","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/bjsm.2007.039974","volume":"42","author":"M Hamer","year":"2008","unstructured":"Hamer M, Chida Y (2008) Walking and primary prevention: a meta-analysis of prospective cohort studies. Br J Sports Med 42:238\u2013243","journal-title":"Br J Sports Med"},{"key":"2743_CR37","unstructured":"World Health Organization (2003) Recommendations for preventing cardiovascular diseases; In: Diet, nutrition and the prevention of chronic diseases. World Health Organization technical report series 916: i\u2013viii, 81\u201394, backcover"},{"key":"2743_CR38","volume-title":"Physical activity assessments for health-related research","author":"CE Matthews","year":"2002","unstructured":"Matthews CE (2002) Use of self-report instruments to assess physical activity. In: Welk GJ (ed) Physical activity assessments for health-related research. Human Kinetics, Champaign"},{"key":"2743_CR39","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1001\/archinte.160.11.1621","volume":"160","author":"LB Andersen","year":"2000","unstructured":"Andersen LB, Schnohr P, Schroll M, Hein HO (2000) All-cause mortality associated with physical activity during leisure time, work, sports, and cycling to work. Arch Intern Med 160:1621\u20131628","journal-title":"Arch Intern Med"},{"key":"2743_CR40","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1249\/MSS.0b013e318180bcad","volume":"40","author":"H Besson","year":"2008","unstructured":"Besson H, Ekelund U, Brage S et al (2008) Relationship between subdomains of total physical activity and mortality. Med Sci Sports Exerc 40:1909\u20131915","journal-title":"Med Sci Sports Exerc"},{"key":"2743_CR41","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/aje\/kwp042","volume":"169","author":"E Stamatakis","year":"2009","unstructured":"Stamatakis E, Hamer M, Lawlor DA (2009) Physical activity, mortality, and cardiovascular disease: is domestic physical activity beneficial? The Scottish Health Survey\u20141995, 1998, and 2003. Am J Epidemiol 169:1191\u20131200","journal-title":"Am J Epidemiol"},{"key":"2743_CR42","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/aje\/kwh195","volume":"160","author":"LB Andersen","year":"2004","unstructured":"Andersen LB (2004) Relative risk of mortality in the physically inactive is underestimated because of real changes in exposure level during follow-up. Am J Epidemiol 160:189\u2013195","journal-title":"Am J Epidemiol"},{"key":"2743_CR43","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.2337\/dc08-0720","volume":"31","author":"AS Brazeau","year":"2008","unstructured":"Brazeau AS, Rabasa-Lhoret R, Strychar I, Mircescu H (2008) Barriers to physical activity among patients with type 1 diabetes. Diabetes Care 31:2108\u20132109","journal-title":"Diabetes Care"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-012-2743-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00125-012-2743-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-012-2743-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T03:11:53Z","timestamp":1643512313000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00125-012-2743-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,10]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["2743"],"URL":"https:\/\/doi.org\/10.1007\/s00125-012-2743-6","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,10]]}}}