{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T23:11:33Z","timestamp":1784329893865,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2015,3,14]],"date-time":"2015-03-14T00:00:00Z","timestamp":1426291200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1007\/s00125-015-3559-y","type":"journal-article","created":{"date-parts":[[2015,3,13]],"date-time":"2015-03-13T06:10:28Z","timestamp":1426227028000},"page":"1167-1174","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["CGM-measured glucose values have a strong correlation with C-peptide, HbA1c and IDAAC, but do poorly in predicting C-peptide levels in the two years following onset of diabetes"],"prefix":"10.1007","volume":"58","author":[{"name":"for the Diabetes Research in Children Network (DirecNet) and Type 1 Diabetes TrialNet Study Groups","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Buckingham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiyao","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy W.","family":"Beck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig","family":"Kollman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina J.","family":"Ruedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart A.","family":"Weinzimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Slover","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew A.","family":"Bremer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Fuqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Tamborlane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,3,14]]},"reference":[{"key":"3559_CR1","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/BF00279611","volume":"30","author":"EB Sochett","year":"1987","unstructured":"Sochett EB, Daneman D, Clarson C, Ehrlich RM (1987) Factors affecting and patterns of residual insulin secretion during the first year of type 1 (insulin-dependent) diabetes mellitus in children. Diabetiologia 30:453\u2013459","journal-title":"Diabetiologia"},{"key":"3559_CR2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0168-8227(91)90135-Z","volume":"11","author":"JJ Couper","year":"1991","unstructured":"Couper JJ, Hudson I, Werther GA, Warne GL, Court JM, Harrison LC (1991) Factors predicting residual \u03b2-cell function in the first year after diagnosis of childhood type 1 diabetes. Diabetes Res Clin Pract 11:9\u201316","journal-title":"Diabetes Res Clin Pract"},{"key":"3559_CR3","doi-asserted-by":"crossref","first-page":"517","DOI":"10.7326\/0003-4819-128-7-199804010-00001","volume":"128","author":"The Diabetes Control and Complications Trial Research Group","year":"1998","unstructured":"The Diabetes Control and Complications Trial Research Group (1998) Effect of intensive therapy on residual \u03b2-cell function in patients with type 1 diabetes in the diabetes control and complications trial. A randomized, controlled trial. Ann Intern Med 128:517\u2013523","journal-title":"Ann Intern Med"},{"key":"3559_CR4","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.2337\/dc08-1987","volume":"32","author":"HB Mortensen","year":"2009","unstructured":"Mortensen HB, Hougaard P, Swift P et al (2009) New definition for the partial remission period in children and adolescents with type 1 diabetes. Diabetes Care 32:1384\u20131390","journal-title":"Diabetes Care"},{"key":"3559_CR5","doi-asserted-by":"crossref","first-page":"4030","DOI":"10.2337\/dc13-1074","volume":"36","author":"B Buckingham","year":"2013","unstructured":"Buckingham B, Beck RW, Ruedy KJ et al (2013) Effectiveness of early intensive therapy on \u03b2-cell preservation in type 1 diabetes. Diabetes Care 36:4030\u20134035","journal-title":"Diabetes Care"},{"key":"3559_CR6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/dia.2012.0289","volume":"15","author":"Diabetes Research in Children Network Study Group, Type 1 Diabetes TrialNet Study Groups","year":"2013","unstructured":"Diabetes Research in Children Network Study Group, Type 1 Diabetes TrialNet Study Groups (2013) The effects of inpatient closed-loop therapy initiated within 1\u00a0week of type 1 diabetes diagnosis. Diabetes Technol Ther 15:1\u20138","journal-title":"Diabetes Technol Ther"},{"key":"3559_CR7","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.2337\/db06-0419","volume":"55","author":"GM Steil","year":"2006","unstructured":"Steil GM, Rebrin K, Darwin C, Hariri F, Saad MF (2006) Feasibility of automating insulin delivery for the treatment of type 1 diabetes. Diabetes 55:3344\u20133350","journal-title":"Diabetes"},{"key":"3559_CR8","doi-asserted-by":"crossref","first-page":"934","DOI":"10.2337\/dc07-1967","volume":"31","author":"SA Weinzimer","year":"2008","unstructured":"Weinzimer SA, Steil GM, Swan KL, Dziura J, Kurtz N, Tamborlane WV (2008) Fully automated closed-loop insulin delivery versus semi-automated hybrid control in pediatric patients with type 1 diabetes using an artificial pancreas. Diabetes Care 31:934\u2013939","journal-title":"Diabetes Care"},{"key":"3559_CR9","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.2337\/dc07-2451","volume":"31","author":"CJ Greenbaum","year":"2008","unstructured":"Greenbaum CJ, Mandrup-Poulsen T, McGee PF et al (2008) Mixed-meal tolerance test versus glucagon stimulation test for the assessment of \u03b2-cell function in therapeutic trials in type 1 diabetes. Diabetes Care 31:1966\u20131971","journal-title":"Diabetes Care"},{"key":"3559_CR10","doi-asserted-by":"crossref","unstructured":"Palmer J, Fleming G, Greenbaum C et al (2004) C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve \u03b2-cell function. Diabetes 53:250\u2013264, Erratum: Diabetes 2004; 53:1934","DOI":"10.2337\/diabetes.53.1.250"},{"key":"3559_CR11","doi-asserted-by":"crossref","first-page":"E2078","DOI":"10.1210\/jc.2012-2115","volume":"97","author":"M-C Vantyghem","year":"2012","unstructured":"Vantyghem M-C, Raverdy V, Balavoine A-S et al (2012) Continuous glucose monitoring after islet transplantation in type 1 diabetes: an excellent graft function (\u00ce2-score greater than 7) is required to abrogate hyperglycemia, whereas a minimal function is necessary to suppress severe hypoglycemia (\u00ce2-score greater than 3). J Clin Endocrinol Metab 97:E2078\u2013E2083","journal-title":"J Clin Endocrinol Metab"},{"key":"3559_CR12","doi-asserted-by":"crossref","first-page":"343","DOI":"10.2337\/diacare.28.2.343","volume":"28","author":"EA Ryan","year":"2005","unstructured":"Ryan EA, Paty BW, Senior PA, Lakey JRT, Bigam D, Shapiro AMJ (2005) \u03b2-Score: an assessment of \u03b2-cell function after islet transplantation. Diabetes Care 28:343\u2013347","journal-title":"Diabetes Care"},{"key":"3559_CR13","doi-asserted-by":"crossref","first-page":"832","DOI":"10.2337\/diacare.26.3.832","volume":"26","author":"MW Steffes","year":"2003","unstructured":"Steffes MW, Sibley S, Jackson M, Thomas W (2003) \u03b2-Cell function and the development of diabetes-related complications in the diabetes control and complications trial. Diabetes Care 26:832\u2013836","journal-title":"Diabetes Care"},{"key":"3559_CR14","doi-asserted-by":"crossref","first-page":"817","DOI":"10.2337\/dc11-2190","volume":"35","author":"J Sherr","year":"2012","unstructured":"Sherr J, Tamborlane WV, Xing D et al (2012) Achievement of target A1c levels with negligible hypoglycemia and low glucose variability in youth with short-term type 1 diabetes and residual \u03b2-cell function. Diabetes Care 35:817\u2013820","journal-title":"Diabetes Care"},{"key":"3559_CR15","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1089\/dia.2013.0042","volume":"15","author":"P Calhoun","year":"2013","unstructured":"Calhoun P, Lum J, Beck R, Kollman C (2013) Performance comparison of the medtronic sof-sensor and enlite glucose sensors in inpatient studies of individuals with type 1 diabetes. Diabetes Technol Ther 15:758\u2013761","journal-title":"Diabetes Technol Ther"},{"key":"3559_CR16","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/j.1464-5491.2011.03545.x","volume":"29","author":"WK Ward","year":"2012","unstructured":"Ward WK, Engle JM, Branigan D, El Youssef J, Massoud RG, Castle JR (2012) The effect of rising vs. falling glucose level on amperometric glucose sensor lag and accuracy in type 1 diabetes. Diabet Med 29:1067\u20131073","journal-title":"Diabet Med"},{"key":"3559_CR17","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/193229681000400127","volume":"4","author":"JR Castle","year":"2010","unstructured":"Castle JR, Ward WK (2010) Amperometric glucose sensors: sources of error and potential benefit of redundancy. J Diabetes Sci Technol 4:221\u2013225","journal-title":"J Diabetes Sci Technol"},{"key":"3559_CR18","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1089\/dia.2006.8.318","volume":"8","author":"Diabetes Research in Children Network (DirecNet) Study Group","year":"2006","unstructured":"Diabetes Research in Children Network (DirecNet) Study Group (2006) Evaluation of factors affecting CGMS calibration. Diabetes Technol Ther 8:318\u2013325","journal-title":"Diabetes Technol Ther"},{"key":"3559_CR19","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1177\/193229681100500318","volume":"5","author":"KL Helton","year":"2011","unstructured":"Helton KL, Ratner BD, Wisniewski NA (2011) Biomechanics of the sensor-tissue interface\u2014effects of motion, pressure, and design on sensor performance and foreign body response\u2014part II: examples and application. J Diabetes Sci Technol 5:647\u2013656","journal-title":"J Diabetes Sci Technol"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-015-3559-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00125-015-3559-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-015-3559-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,2]],"date-time":"2022-05-02T13:03:59Z","timestamp":1651496639000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00125-015-3559-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,14]]},"references-count":19,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["3559"],"URL":"https:\/\/doi.org\/10.1007\/s00125-015-3559-y","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,14]]}}}