{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:02:47Z","timestamp":1792677767263,"version":"4.5.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2015,9,24]],"date-time":"2015-09-24T00:00:00Z","timestamp":1443052800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1007\/s00125-015-3772-8","type":"journal-article","created":{"date-parts":[[2015,9,24]],"date-time":"2015-09-24T15:44:31Z","timestamp":1443109471000},"page":"2861-2866","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":104,"title":["Impaired mitochondrial oxidative phosphorylation and supercomplex assembly in rectus abdominis muscle of diabetic obese individuals"],"prefix":"10.1007","volume":"58","author":[{"given":"Ghadi","family":"Antoun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiona","family":"McMurray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Brianne","family":"Thrush","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Patten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa C.","family":"Peixoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth S.","family":"Slack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth","family":"McPherson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Dent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary-Ellen","family":"Harper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,9,24]]},"reference":[{"key":"3772_CR1","doi-asserted-by":"crossref","first-page":"2944","DOI":"10.2337\/diabetes.51.10.2944","volume":"51","author":"DE Kelley","year":"2002","unstructured":"Kelley DE, He J, Menshikova EV, Ritov VB (2002) Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51:2944\u20132950","journal-title":"Diabetes"},{"key":"3772_CR2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/ng1180","volume":"34","author":"VK Mootha","year":"2003","unstructured":"Mootha VK, Lindgren CM, Eriksson KF et al (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34:267\u2013273","journal-title":"Nat Genet"},{"key":"3772_CR3","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1172\/JCI25758","volume":"115","author":"DE Kelley","year":"2005","unstructured":"Kelley DE (2005) Skeletal muscle fat oxidation: timing and flexibility are everything. J Clin Invest 115:1699\u20131702","journal-title":"J Clin Invest"},{"key":"3772_CR4","doi-asserted-by":"crossref","first-page":"E49","DOI":"10.1152\/ajpendo.00317.2009","volume":"298","author":"VB Ritov","year":"2010","unstructured":"Ritov VB, Menshikova EV, Azuma K et al (2010) Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. Am J Physiol Endocrinol Metab 298:E49\u2013E58","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"3772_CR5","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1210\/jc.2014-2512","volume":"99","author":"JP DeLany","year":"2014","unstructured":"DeLany JP, Dube JJ, Standley RA et al (2014) Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity. J Clin Endocrinol Metab 99:4307\u20134314","journal-title":"J Clin Endocrinol Metab"},{"key":"3772_CR6","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1126\/science.1230381","volume":"340","author":"E Lapuente-Brun","year":"2013","unstructured":"Lapuente-Brun E, Moreno-Loshuertos R, Acin-Perez R et al (2013) Supercomplex assembly determines electron flux in the mitochondrial electron transport chain. Science 340:1567\u20131570","journal-title":"Science"},{"key":"3772_CR7","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/978-1-61779-382-0_3","volume":"810","author":"D Pesta","year":"2012","unstructured":"Pesta D, Gnaiger E (2012) High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibres from small biopsies of human muscle. Methods Mol Biol 810:25\u201358","journal-title":"Methods Mol Biol"},{"key":"3772_CR8","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.2337\/db06-0981","volume":"56","author":"M Mogensen","year":"2007","unstructured":"Mogensen M, Sahlin K, Fernstrom M et al (2007) Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes. Diabetes 56:1592\u20131599","journal-title":"Diabetes"},{"key":"3772_CR9","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2337\/diabetes.54.1.8","volume":"54","author":"VB Ritov","year":"2005","unstructured":"Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE (2005) Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54:8\u201314","journal-title":"Diabetes"},{"key":"3772_CR10","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1007\/s00125-007-0594-3","volume":"50","author":"R Boushel","year":"2007","unstructured":"Boushel R, Gnaiger E, Schjerling P, Skovbro M, Kraunsoe R, Dela F (2007) Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50:790\u2013796","journal-title":"Diabetologia"},{"key":"3772_CR11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.yjmcc.2014.11.008","volume":"79","author":"D Thapa","year":"2015","unstructured":"Thapa D, Nichols CE, Lewis SE et al (2015) Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction. J Mol Cell Cardiol 79:212\u2013223","journal-title":"J Mol Cell Cardiol"}],"updated-by":[{"DOI":"10.1007\/s00125-015-3821-3","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T00:00:00Z","timestamp":1448496000000}}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-015-3772-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00125-015-3772-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-015-3772-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T07:54:00Z","timestamp":1558598040000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00125-015-3772-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,24]]},"references-count":11,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["3772"],"URL":"https:\/\/doi.org\/10.1007\/s00125-015-3772-8","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s00125-015-3821-3","asserted-by":"object"}]},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,24]]}}}