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It was also supported by fellowships from the American Heart Association (14POST20480294) to LR and the Middle-East Diabetes Research Center to HEG and SSG. The studies were also partially supported by the John J. Kopchick PhD OHF Eminent Research Chair Fund.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors declare that there is no duality of interest associated with this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Duality of interest"}},{"value":"LR, HTM, HEG, SSG, TAB, H-LN and SD researched data and drafted parts of the manuscript. HTM and HEG revised the manuscript extensively. JKK carried out the hyperinsulinaemic\u2013euglycaemic clamp experiment, and analysed and discussed data. GYD and GH carried out the statistical analysis. GYD, GH and JKK critically reviewed the manuscript. SMN was responsible for study design, conceptualisation, data analysis and interpretation, and reviewing the manuscript. All authors have given final approval of this version to be published. SMN had full access to all the data of the study and takes responsibility for the integrity and accuracy of data analysis and the decision to submit and publish the manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Contribution statement"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}