{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T01:48:21Z","timestamp":1789436901066,"version":"build-2803163510"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T00:00:00Z","timestamp":1508716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ, Brazil)"},{"name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq, Brazil)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1007\/s00125-017-4484-z","type":"journal-article","created":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T00:38:17Z","timestamp":1508805497000},"page":"455-465","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Aortic stiffness and ambulatory blood pressure as predictors of diabetic kidney disease: a competing risks analysis from the Rio de Janeiro Type 2 Diabetes Cohort Study"],"prefix":"10.1007","volume":"61","author":[{"given":"Claudia R. L.","family":"Cardoso","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie C.","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme C.","family":"Salles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel T.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil F.","family":"Salles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,10,23]]},"reference":[{"key":"4484_CR1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/S2213-8587(13)70112-8","volume":"2","author":"PZ Zimmet","year":"2014","unstructured":"Zimmet PZ, Magliano DJ, Herman WH, Shaw JE (2014) Diabetes: a 21st century challenge. Lancet Diabetes Endocrinol 2:56\u201364","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"2 Suppl 2","key":"4484_CR2","doi-asserted-by":"publisher","first-page":"S39","DOI":"10.1053\/j.ajkd.2013.10.048","volume":"63","author":"RJ Macisaac","year":"2014","unstructured":"Macisaac RJ, Ekinci EI, Jerums G (2014) Markers of and risk factors for the development and progression of diabetic kidney disease. Am J Kidney Dis 63(2 Suppl 2):S39\u2013S62","journal-title":"Am J Kidney Dis"},{"key":"4484_CR3","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/S0140-6736(13)60687-X","volume":"382","author":"V Jha","year":"2013","unstructured":"Jha V, Garcia-Garcia G, Iseki K et al (2013) Chronic kidney disease: global dimension and perspectives. Lancet 382:260\u2013272","journal-title":"Lancet"},{"key":"4484_CR4","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1681\/ASN.2012070718","volume":"24","author":"M Afkarian","year":"2013","unstructured":"Afkarian M, Sachs MC, Kestenbaum B et al (2013) Kidney disease and increased mortality risk in type 2 diabetes. J Am Soc Nephrol 24:302\u2013308","journal-title":"J Am Soc Nephrol"},{"key":"4484_CR5","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1001\/archinternmed.2011.2230","volume":"172","author":"SG Coca","year":"2012","unstructured":"Coca SG, Ismail-Beigi F, Haq N, Krumholz HM, Parikh CR (2012) Role of intensive glucose control in development of renal end points in type 2 diabetes mellitus: systematic review and meta-analysis intensive glucose control in type 2 diabetes. Arch Intern Med 172:761\u2013769","journal-title":"Arch Intern Med"},{"key":"4484_CR6","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/ki.2012.401","volume":"83","author":"V Perkovic","year":"2013","unstructured":"Perkovic V, Heerspink HL, Chalmers J et al (2013) Intensive glucose control improves kidney outcomes in patients with type 2 diabetes. Kidney Int 83:517\u2013523","journal-title":"Kidney Int"},{"key":"4484_CR7","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1001\/jama.2014.18574","volume":"313","author":"CA Emdin","year":"2015","unstructured":"Emdin CA, Rahimi K, Neal B, Callender T, Perkovic V, Patel A (2015) Blood pressure lowering in type 2 diabetes: a systematic review and meta-analysis. JAMA 313:603\u2013615","journal-title":"JAMA"},{"key":"4484_CR8","doi-asserted-by":"publisher","first-page":"2782","DOI":"10.2337\/dc14-0284","volume":"37","author":"RJ Anderson","year":"2014","unstructured":"Anderson RJ, Bahn GD, Emanuele NV, Marks JB, Duckworth WC, VADT Study Group (2014) Blood pressure and pulse pressure effects on renal outcomes in the veterans affairs diabetes trial (VADT). Diabetes Care 37:2782\u20132788","journal-title":"Diabetes Care"},{"key":"4484_CR9","doi-asserted-by":"publisher","first-page":"d4169","DOI":"10.1136\/bmj.d4169","volume":"343","author":"R Boussageon","year":"2011","unstructured":"Boussageon R, Bejan-Angoulvant T, Saadatian-Elahi M et al (2011) Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: meta-analysis of randomised controlled trials. BMJ 343:d4169","journal-title":"BMJ"},{"key":"4484_CR10","doi-asserted-by":"publisher","first-page":"i717","DOI":"10.1136\/bmj.i717","volume":"352","author":"M Brunstr\u00f6m","year":"2016","unstructured":"Brunstr\u00f6m M, Carlberg B (2016) Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses. BMJ 352:i717","journal-title":"BMJ"},{"key":"4484_CR11","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.2337\/dc09-0959","volume":"32","author":"S Zoungas","year":"2009","unstructured":"Zoungas S, de Galan BE, Ninomiya T et al (2009) Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: new results from the ADVANCE. Diabetes Care 32:2068\u20132074","journal-title":"Diabetes Care"},{"key":"4484_CR12","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1038\/ki.2011.415","volume":"81","author":"F Ismail-Beigi","year":"2012","unstructured":"Ismail-Beigi F, Craven TE, O\u2019Connor PJ et al (2012) Combined intensive blood pressure and glycemic control does not produce an additive benefit on microvascular outcomes in type 2 diabetic patients. Kidney Int 81:586\u2013594","journal-title":"Kidney Int"},{"key":"4484_CR13","doi-asserted-by":"publisher","first-page":"694","DOI":"10.2337\/dc15-2322","volume":"39","author":"MG Wong","year":"2016","unstructured":"Wong MG, Perkovic V, Chalmers J et al (2016) Long-term benefits of intensive glucose control for preventing end-stage kidney disease: ADVANCE-ON. Diabetes Care 39:694\u2013700","journal-title":"Diabetes Care"},{"key":"4484_CR14","doi-asserted-by":"publisher","first-page":"2332","DOI":"10.1097\/HJH.0000000000000355","volume":"32","author":"GC Roush","year":"2014","unstructured":"ABC-H Investigators, Roush GC, Fagard RH, Salles GF et al (2014) Prognostic impact from clinic, daytime, and night-time systolic blood pressure in nine cohorts of 13,844 patients with hypertension. J Hypertens 32:2332\u20132340","journal-title":"J Hypertens"},{"key":"4484_CR15","doi-asserted-by":"publisher","first-page":"2176","DOI":"10.1097\/HJH.0b013e328364103f","volume":"31","author":"GF Salles","year":"2013","unstructured":"Salles GF, Leite NC, Pereira BB, Nascimento EM, Cardoso CR (2013) Prognostic impact of clinic and ambulatory blood pressure components in high-risk type 2 diabetic patients: the Rio de Janeiro Type 2 Diabetes Cohort Study. J Hypertens 31:2176\u20132186","journal-title":"J Hypertens"},{"key":"4484_CR16","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1161\/01.HYP.0000232644.98208.65","volume":"48","author":"W Palmas","year":"2006","unstructured":"Palmas W, Moran A, Pickering T et al (2006) Ambulatory pulse pressure and progression of urinary albumin excretion in older patients with type 2 diabetes mellitus. Hypertension 48:301\u2013308","journal-title":"Hypertension"},{"key":"4484_CR17","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1007\/s00125-009-1262-6","volume":"52","author":"ST Knudsen","year":"2009","unstructured":"Knudsen ST, Laugesen E, Hansen KW, Bek T, Mogensen CE, Poulsen PL (2009) Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients. Diabetologia 52:698\u2013704","journal-title":"Diabetologia"},{"key":"4484_CR18","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1016\/j.jacc.2010.12.017","volume":"57","author":"JL Cavalcante","year":"2011","unstructured":"Cavalcante JL, Lima JA, Redheuil A, Al-Mallah MH (2011) Aortic stiffness: current understanding and future directions. J Am Coll Cardiol 57:1511\u20131522","journal-title":"J Am Coll Cardiol"},{"key":"4484_CR19","doi-asserted-by":"publisher","first-page":"448","DOI":"10.2337\/diabetes.52.2.448","volume":"52","author":"E Kimoto","year":"2003","unstructured":"Kimoto E, Shoji T, Shinohara K et al (2003) Preferential stiffening of central over peripheral arteries in type 2 diabetes. Diabetes 52:448\u2013452","journal-title":"Diabetes"},{"key":"4484_CR20","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1111\/dme.12461","volume":"31","author":"JJ Liu","year":"2014","unstructured":"Liu JJ, Tavintharan S, Yeoh LY et al (2014) High normal albuminuria is independently associated with aortic stiffness in patients with type 2 diabetes. Diabet Med 31:1199\u20131204","journal-title":"Diabet Med"},{"key":"4484_CR21","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1016\/j.atherosclerosis.2008.12.027","volume":"205","author":"CR Cardoso","year":"2009","unstructured":"Cardoso CR, Ferreira MT, Leite NC, Barros PN, Conte PH, Salles GF (2009) Microvascular degenerative complications are associated with increased aortic stiffness in type 2 diabetic patients. Atherosclerosis 205:472\u2013476","journal-title":"Atherosclerosis"},{"key":"4484_CR22","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.diabet.2013.09.008","volume":"40","author":"P Sj\u00f6blom","year":"2014","unstructured":"Sj\u00f6blom P, Nystrom FH, L\u00e4nne T, Engvall J, \u00d6stgren CJ (2014) Microalbuminuria, but not reduced eGFR, is associated with cardiovascular subclinical organ damage in type 2 diabetes. Diabetes Metab 40:49\u201355","journal-title":"Diabetes Metab"},{"key":"4484_CR23","doi-asserted-by":"publisher","first-page":"2570","DOI":"10.2337\/dc11-1020","volume":"34","author":"R Bouchi","year":"2011","unstructured":"Bouchi R, Babazono T, Mugishima M et al (2011) Arterial stiffness is associated with incident albuminuria and decreased glomerular filtration rate in type 2 diabetic patients. Diabetes Care 34:2570\u20132575","journal-title":"Diabetes Care"},{"key":"4484_CR24","doi-asserted-by":"publisher","first-page":"309294","DOI":"10.1155\/2013\/309294","volume":"2013","author":"YJ Sheen","year":"2013","unstructured":"Sheen YJ, Lin JL, Li TC, Bau CT, Sheu WH (2013) Peripheral arterial stiffness is independently associated with a rapid decline in estimated glomerular filtration rate in patients with type 2 diabetes. Biomed Res Int 2013:309294","journal-title":"Biomed Res Int"},{"key":"4484_CR25","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.1007\/s00125-015-3658-9","volume":"58","author":"CR Cardoso","year":"2015","unstructured":"Cardoso CR, Moran CB, Marinho FS, Ferreira MT, Salles GF (2015) Increased aortic stiffness predicts future development and progression of peripheral neuropathy in patients with type 2 diabetes: the Rio de Janeiro Type 2 Diabetes Cohort Study. Diabetologia 58:2161\u20132168","journal-title":"Diabetologia"},{"key":"4484_CR26","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1038\/ajh.2011.168","volume":"25","author":"CR Cardoso","year":"2012","unstructured":"Cardoso CR, Leite NC, Muxfeldt ES, Salles GF (2012) Thresholds of ambulatory blood pressure associated with chronic complications in type 2 diabetes. Am J Hypertens 25:82\u201388","journal-title":"Am J Hypertens"},{"key":"4484_CR27","doi-asserted-by":"publisher","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","volume":"150","author":"AS Levey","year":"2009","unstructured":"Levey AS, Stevens LA, Schmid CH et al (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150:604\u2013612","journal-title":"Ann Intern Med"},{"key":"4484_CR28","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1097\/HJH.0b013e328363e964","volume":"31","author":"E O\u2019Brien","year":"2013","unstructured":"O\u2019Brien E, Parati G, Stergiou G et al (2013) European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens 31:1731\u20131768","journal-title":"J Hypertens"},{"key":"4484_CR29","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1373\/clinchem.2006.077180","volume":"53","author":"AS Levey","year":"2007","unstructured":"Levey AS, Coresh J, Greene T et al (2007) Expressing the modification of diet in renal disease study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin Chem 53:766\u2013772","journal-title":"Clin Chem"},{"key":"4484_CR30","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1097\/HJH.0b013e32834fa8b0","volume":"30","author":"LM Bortel Van","year":"2012","unstructured":"Van Bortel LM, Laurent S, Boutouyrie P et al (2012) Expert consensus document on the measurement of aortic stiffness in daily practice using carotid-femoral pulse wave velocity. J Hypertens 30:445\u2013448","journal-title":"J Hypertens"},{"key":"4484_CR31","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","volume":"94","author":"JP Fine","year":"1999","unstructured":"Fine JP, Gray RJ (1999) A proportional hazards model for the subdistribution of a competing risk. J Am Stat Assoc 94:496\u2013509","journal-title":"J Am Stat Assoc"},{"key":"4484_CR32","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1097\/MNH.0b013e3283456546","volume":"20","author":"RJ Macisaac","year":"2011","unstructured":"Macisaac RJ, Jerums G (2011) Diabetic kidney disease with and without albuminuria. Curr Opin Nephrol Hypertens 20:246\u2013257","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"4484_CR33","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1111\/jdi.12533","volume":"8","author":"NJ Radcliffe","year":"2017","unstructured":"Radcliffe NJ, Seah JM, Clarke M, MacIsaac RJ, Jerums G, Ekinci EI (2017) Clinical predictive factors in diabetic kidney disease progression. J Diabetes Investig 8:6\u201318","journal-title":"J Diabetes Investig"},{"key":"4484_CR34","doi-asserted-by":"publisher","first-page":"2044","DOI":"10.3390\/ijms17122044","volume":"17","author":"CR Cardoso","year":"2016","unstructured":"Cardoso CR, Salles GF (2016) Aortic stiffness as a surrogate endpoint to micro- and macrovascular complications in patients with type 2 diabetes. Int J Mol Sci 17:2044","journal-title":"Int J Mol Sci"},{"key":"4484_CR35","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1161\/01.HYP.0000216634.73504.7d","volume":"47","author":"A Moran","year":"2006","unstructured":"Moran A, Palmas W, Pickering TG et al (2006) Office and ambulatory blood pressure are independently associated with albuminuria in older subjects with type 2 diabetes. Hypertension 47:955\u2013961","journal-title":"Hypertension"},{"key":"4484_CR36","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1056\/NEJMoa013410","volume":"347","author":"E Lurbe","year":"2002","unstructured":"Lurbe E, Redon J, Kesani A et al (2002) Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes. N Engl J Med 347:797\u2013805","journal-title":"N Engl J Med"},{"key":"4484_CR37","doi-asserted-by":"publisher","unstructured":"Sweeting MJ, Barrett JK, Thompson SG, Wood AM (2016) The use of repeated blood pressure measures for cardiovascular risk prediction: a comparison of statistical models in the ARIC study. Stat Med. \n                    https:\/\/doi.org\/10.1002\/sim.7144","DOI":"10.1002\/sim.7144"},{"key":"4484_CR38","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/j.1524-6175.2007.07170.x","volume":"10","author":"W Palmas","year":"2008","unstructured":"Palmas W, Pickering T, Teresi J et al (2008) Nocturnal blood pressure elevation predicts progression of albuminuria in elderly people with type 2 diabetes. J Clin Hypertens (Greenwich) 10:12\u201320","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"4484_CR39","doi-asserted-by":"publisher","first-page":"1575","DOI":"10.1056\/NEJMoa1001286","volume":"362","author":"The ACCORD Study Group","year":"2010","unstructured":"The ACCORD Study Group (2010) Effects of intensive blood-pressure control in type 2 diabetes mellitus. N Engl J Med 362:1575\u20131585","journal-title":"N Engl J Med"},{"key":"4484_CR40","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1001\/jama.2010.884","volume":"304","author":"RM Cooper-DeHoff","year":"2010","unstructured":"Cooper-DeHoff RM, Gong Y, Handberg EM et al (2010) Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. JAMA 304:61\u201368","journal-title":"JAMA"},{"key":"4484_CR41","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1056\/NEJMoa1111732","volume":"365","author":"The DCCT\/EDIC Research Group","year":"2011","unstructured":"The DCCT\/EDIC Research Group (2011) Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. N Engl J Med 365:2366\u20132376","journal-title":"N Engl J Med"},{"key":"4484_CR42","doi-asserted-by":"publisher","first-page":"2090","DOI":"10.2337\/dc11-0175","volume":"34","author":"L Agrawal","year":"2011","unstructured":"Agrawal L, Azad N, Emanuele NV et al (2011) Observation on renal outcomes in the Veterans Affairs Diabetes Trial. Diabetes Care 34:2090\u20132094","journal-title":"Diabetes Care"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00125-017-4484-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-017-4484-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-017-4484-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T08:36:10Z","timestamp":1540370170000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00125-017-4484-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,23]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["4484"],"URL":"https:\/\/doi.org\/10.1007\/s00125-017-4484-z","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,23]]}}}