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All referenced macros (adopted and developed), calculations, programming code and numerical dataset files (including individual-level donor data) are freely available on GitHub through Zenodo at","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"This research was performed with the support of the nPOD, a collaborative type 1 diabetes research project, and was sponsored by the JDRF (25-2013-268, 25-2012-380, and 25-2007-874 to MAA, including a subcontract to JSK). Funding was also provided by the National Institutes of Health Human Islet Research Network (NIH HIRN, U01DK104147 to JSK) and a program project grant (P01 AI42288 to MAA).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"MAA and AP serve as executive directors of the nPOD program and JSK directs its data management core. All other authors declare that there is no duality of interest associated with their contribution to this manuscript.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Duality of interest"}},{"value":"IK conceived of the study, acquired and interpreted data and drafted and edited the manuscript. MB acquired and interpreted data. TP, SS and CW acquired data. AM analysed and interpreted data and edited the manuscript. PJ contributed to the conception of the study. AP, DS and JAL interpreted the data. MAA conceived of the study and edited the manuscript. JSK conceived of the study, analysed and interpreted the data and drafted and edited the manuscript. All authors critically reviewed the manuscript and approved the final version. JSK is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Contribution statement"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}