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At each wave, each physician collected data from ten consecutive participants with type 2 diabetes during a 2\u00a0week period. The primary objective of this analysis was to evaluate trends of glycaemic control over time.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 66,088 individuals with type 2 diabetes were recruited by 6099 physicians from 49 countries. The proportion of participants with HbA<jats:sub>1c<\/jats:sub> &lt;53\u00a0mmol\/mol (&lt;7%) decreased from 36% in wave 1 (2005) to 30.1% in wave 7 (2017) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Compared with wave 1, the adjusted ORs of attaining HbA<jats:sub>1c<\/jats:sub> \u226464\u00a0mmol\/mol (\u22648%) decreased significantly in waves 2, 5, 6 and 7 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Over 80% of participants received oral glucose-lowering drugs, with declining use of sulfonylureas. Insulin use increased from 32.8% (wave 1) to 41.2% (wave 7) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). The corresponding time to insulin initiation (mean \u00b1 SD) changed from 8.4\u2009\u00b1\u20096.9 in wave 1 to 8.3\u2009\u00b1\u20096.6\u00a0years in wave 7, while daily insulin dosage ranged from 0.39\u2009\u00b1\u20090.21\u00a0U\/kg (wave 1) to 0.33\u2009\u00b1\u20090.19\u00a0U\/kg (wave 7) for basal regimen and 0.70\u2009\u00b1\u20090.34\u00a0U\/kg (wave 1) to 0.77\u2009\u00b1\u20090.33 (wave 7) U\/kg for basal\u2013bolus regimen. An increasing proportion of participants had \u22652 HbA<jats:sub>1c<\/jats:sub> measurements within 12\u00a0months of enrolment (from 61.8% to 92.9%), and the proportion of participants receiving diabetes education (mainly delivered by physicians) also increased from 59.0% to 78.3%.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>In developing countries, glycaemic control in individuals with type 2 diabetes remained suboptimal over a 12\u00a0year period, indicating a need for system changes and better organisation of care to improve self-management and attainment of treatment goals.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00125-019-05078-3","type":"journal-article","created":{"date-parts":[[2020,1,4]],"date-time":"2020-01-04T10:02:30Z","timestamp":1578132150000},"page":"711-721","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":107,"title":["Persistent poor glycaemic control in individuals with type 2 diabetes in developing countries: 12\u00a0years of real-world evidence of the International Diabetes Management Practices Study (IDMPS)"],"prefix":"10.1007","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6860-3620","authenticated-orcid":false,"given":"Pablo","family":"Aschner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"Gagliardino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Ilkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Lavalle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambady","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Claude","family":"Mbanya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Shestakova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Chantelot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana C. 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