{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T00:27:05Z","timestamp":1790468825875,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Diabetologia"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s00125-021-05440-4","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T10:03:10Z","timestamp":1617098590000},"page":"1442-1446","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Assessing data on the incidence of lower limb amputation in diabetes"],"prefix":"10.1007","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1744-7576","authenticated-orcid":false,"given":"William","family":"Jeffcoate","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Game","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Morbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Narres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristien","family":"Van Acker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Icks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,30]]},"reference":[{"issue":"12","key":"5440_CR1","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1007\/s00125-004-1584-3","volume":"47","author":"WJ Jeffcoate","year":"2004","unstructured":"Jeffcoate WJ, van Houtum WH (2004) Amputation as a marker of the quality of foot care in diabetes. Diabetologia 47(12):2051\u20132058. https:\/\/doi.org\/10.1007\/s00125-004-1584-3","journal-title":"Diabetologia"},{"issue":"8","key":"5440_CR2","doi-asserted-by":"publisher","first-page":"128","DOI":"10.3238\/arztebl.2017.0128","volume":"114","author":"G R\u00fcmenapf","year":"2017","unstructured":"R\u00fcmenapf G, Morbach S (2017) Amputation Statistics\u2014How to Interpret Them? Dtsch Arztebl Int 114(8):128\u2013129. https:\/\/doi.org\/10.3238\/arztebl.2017.0128","journal-title":"Dtsch Arztebl Int"},{"issue":"8","key":"5440_CR3","doi-asserted-by":"publisher","first-page":"e0182081","DOI":"10.1371\/journal.pone.0182081","volume":"12","author":"M Narres","year":"2017","unstructured":"Narres M, Kvitkina T, Claessen H et al (2017) Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: A systematic review. PLoS One 12(8):e0182081. https:\/\/doi.org\/10.1371\/journal.pone.0182081","journal-title":"PLoS One"},{"issue":"9","key":"5440_CR4","doi-asserted-by":"publisher","first-page":"1966","DOI":"10.1007\/s00125-018-4655-6","volume":"61","author":"H Claessen","year":"2018","unstructured":"Claessen H, Avalosse H, Guillaume J et al (2018) Decreasing rates of major lower-extremity amputation in people with diabetes but not in those without: a nationwide study in Belgium. Diabetologia 61(9):1966\u20131977. https:\/\/doi.org\/10.1007\/s00125-018-4655-6","journal-title":"Diabetologia"},{"issue":"24","key":"5440_CR5","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.1056\/NEJMra1615439","volume":"376","author":"DG Armstrong","year":"2017","unstructured":"Armstrong DG, Boulton AJM, Bus SA (2017) Diabetic Foot Ulcers and Their Recurrence. N Engl J Med 376(24):2367\u20132375. https:\/\/doi.org\/10.1056\/NEJMra1615439","journal-title":"N Engl J Med"},{"issue":"1","key":"5440_CR6","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s13047-020-00383-2","volume":"13","author":"DG Armstrong","year":"2020","unstructured":"Armstrong DG, Swerdlow MA, Armstrong AA, Conte MS, Padula WV, Bus SA (2020) Five year mortality and direct costs of care for people with diabetic foot complications are comparable to cancer. J Foot Ankle Res 13(1):16. https:\/\/doi.org\/10.1186\/s13047-020-00383-2","journal-title":"J Foot Ankle Res"},{"issue":"8","key":"5440_CR7","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1111\/dme.13973","volume":"36","author":"M Kerr","year":"2019","unstructured":"Kerr M, Barron E, Chadwick P et al (2019) The cost of diabetic foot ulcers and amputations to the National Health Service in England. Diabet Med 36(8):995\u20131002. https:\/\/doi.org\/10.1111\/dme.13973","journal-title":"Diabet Med"},{"issue":"Suppl 1","key":"5440_CR8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1002\/dmrr.2245","volume":"28","author":"P Cavanagh","year":"2012","unstructured":"Cavanagh P, Attinger C, Abbas Z, Bal A, Rojas N, Xu ZR (2012) Cost of treating diabetic foot ulcers in five different countries. Diabetes Metab Res Rev 28(Suppl 1):107\u2013111. https:\/\/doi.org\/10.1002\/dmrr.2245","journal-title":"Diabetes Metab Res Rev"},{"key":"5440_CR9","unstructured":"NHS Digital (2019). National Diabetes Foot Care Audit, 2014-2018. Available from: https:\/\/digital.nhs.uk\/data-and-information\/publications\/statistical\/national-diabetes-footcare-audit\/2014-2018. Accessed 16 Sept 2020"},{"issue":"6","key":"5440_CR10","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1007\/s00125-017-4518-6","volume":"61","author":"R Farmer","year":"2018","unstructured":"Farmer R, Mathur R, Bhaskaran K, Eastwood SV, Chaturvedi N, Smeeth L (2018) Promises and pitfalls of electronic health record analysis. Diabetologia 61(6):1241\u20131248. https:\/\/doi.org\/10.1007\/s00125-017-4518-6","journal-title":"Diabetologia"},{"issue":"1","key":"5440_CR11","doi-asserted-by":"publisher","first-page":"50","DOI":"10.2337\/dc18-1380","volume":"42","author":"LS Geiss","year":"2019","unstructured":"Geiss LS, Li Y, Hora I, Albright A, Rolka D, Gregg EW (2019) Resurgence of Diabetes-Related Nontraumatic Lower-Extremity Amputation in the Young and Middle-Aged Adult U.S. Population. Diabetes Care 42(1):50\u201354. https:\/\/doi.org\/10.2337\/dc18-1380","journal-title":"Diabetes Care"},{"issue":"4","key":"5440_CR12","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1111\/dme.1210810.1111\/dme.12108","volume":"30","author":"GP Leese","year":"2013","unstructured":"Leese GP, Feng Z, Leese RM, Dibben C, Emslie-Smith A (2013) Impact of health-care accessibility and social deprivation on diabetes related foot disease. Diabet Med 30(4):484\u2013490. https:\/\/doi.org\/10.1111\/dme.1210810.1111\/dme.12108","journal-title":"Diabet Med"},{"issue":"4","key":"5440_CR13","doi-asserted-by":"publisher","first-page":"e002395","DOI":"10.1136\/bmjopen-2012-002395","volume":"3","author":"M Venermo","year":"2013","unstructured":"Venermo M, Manderbacka K, Ikonen T, Keskimaki I, Winell K, Sund R (2013) Amputations and socioeconomic position among persons with diabetes mellitus, a population-based register study. BMJ Open 3(4):e002395. https:\/\/doi.org\/10.1136\/bmjopen-2012-002395","journal-title":"BMJ Open"},{"issue":"7","key":"5440_CR14","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.2337\/dc05-1942","volume":"29","author":"RH Glazier","year":"2006","unstructured":"Glazier RH, Bajcar J, Kennie NR, Willson K (2006) A systematic review of interventions to improve diabetes care in socially disadvantaged populations. Diabetes Care 29(7):1675\u20131688. https:\/\/doi.org\/10.2337\/dc05-1942","journal-title":"Diabetes Care"},{"issue":"3","key":"5440_CR15","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1007\/s00125-019-05056-9","volume":"63","author":"JE Hurst","year":"2020","unstructured":"Hurst JE, Barn R, Gibson L et al (2020) Geospatial mapping and data linkage uncovers variability in outcomes of foot disease according to multiple deprivation: a population cohort study of people with diabetes. Diabetologia 63(3):659\u2013667. https:\/\/doi.org\/10.1007\/s00125-019-05056-9","journal-title":"Diabetologia"},{"key":"5440_CR16","doi-asserted-by":"publisher","unstructured":"Margolis DJ, Hampton M, Hoffstad O, Malay DS, Thom S (2015) Health literacy and diabetic foot ulcer healing. Wound Repair Regen 23(3):299\u2013301. https:\/\/doi.org\/10.1111\/wrr.12311","DOI":"10.1111\/wrr.12311"},{"issue":"1","key":"5440_CR17","doi-asserted-by":"publisher","first-page":"48","DOI":"10.2337\/diacare.19.1.48","volume":"19","author":"LA Lavery","year":"1996","unstructured":"Lavery LA, Ashry HR, van Houtum W, Pugh JA, Harkless LB, Basu S (1996) Variation in the incidence and proportion of diabetes-related amputations in minorities. Diabetes Care 19(1):48\u201352. https:\/\/doi.org\/10.2337\/diacare.19.1.48","journal-title":"Diabetes Care"},{"issue":"7","key":"5440_CR18","doi-asserted-by":"publisher","first-page":"421","DOI":"10.5694\/j.1326-5377.2010.tb03571.x","volume":"192","author":"PE Norman","year":"2010","unstructured":"Norman PE, Schoen DE, Gurr JM, Kolybaba ML (2010) High rates of amputation among Indigenous people in Western Australia. Med J Aust 192(7):421. https:\/\/doi.org\/10.5694\/j.1326-5377.2010.tb03571.x","journal-title":"Med J Aust"},{"issue":"7\u20138","key":"5440_CR19","doi-asserted-by":"publisher","first-page":"868","DOI":"10.1111\/ans.15079","volume":"89","author":"JK Gurney","year":"2019","unstructured":"Gurney JK, Stanley J, York S, Sarfati D (2019) Regional variation in the risk of lower-limb amputation among patients with diabetes in New Zealand. ANZ J Surg 89(7\u20138):868\u2013873. https:\/\/doi.org\/10.1111\/ans.15079","journal-title":"ANZ J Surg"},{"issue":"8","key":"5440_CR20","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.2337\/diacare.28.8.1869","volume":"28","author":"CA Abbott","year":"2005","unstructured":"Abbott CA, Garrow AP, Carrington AL, Morris J, Van Ross ER, Boulton AJ (2005) Foot ulcer risk is lower in South-Asian and african-Caribbean compared with European diabetic patients in the U.K.: the North-West diabetes foot care study. Diabetes Care 28(8):1869\u20131875. https:\/\/doi.org\/10.2337\/diacare.28.8.1869","journal-title":"Diabetes Care"},{"issue":"6","key":"5440_CR21","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.2337\/dc09-2067","volume":"33","author":"CA Abbott","year":"2010","unstructured":"Abbott CA, Chaturvedi N, Malik RA et al (2010) Explanations for the lower rates of diabetic neuropathy in Indian Asians versus Europeans. Diabetes Care 33(6):1325\u20131330. https:\/\/doi.org\/10.2337\/dc09-2067","journal-title":"Diabetes Care"},{"issue":"5","key":"5440_CR22","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1007\/s11886-014-0476-5","volume":"16","author":"A Shah","year":"2014","unstructured":"Shah A, Kanaya AM (2014) Diabetes and associated complications in the South Asian population. Curr Cardiol Rep 16(5):476. https:\/\/doi.org\/10.1007\/s11886-014-0476-5","journal-title":"Curr Cardiol Rep"},{"issue":"2","key":"5440_CR23","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1136\/heartjnl-2013-303605","volume":"100","author":"M Sebastianski","year":"2014","unstructured":"Sebastianski M, Makowsky MJ, Dorgan M, Tsuyuki RT (2014) Paradoxically lower prevalence of peripheral arterial disease in South Asians: a systematic review and meta-analysis. Heart 100(2):100\u2013105. https:\/\/doi.org\/10.1136\/heartjnl-2013-303605","journal-title":"Heart"},{"issue":"1","key":"5440_CR24","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1001\/archinte.162.1.73","volume":"162","author":"S Leggetter","year":"2002","unstructured":"Leggetter S, Chaturvedi N, Fuller JH, Edmonds ME (2002) Ethnicity and risk of diabetes-related lower extremity amputation: a population-based, case-control study of African Caribbeans and Europeans in the United kingdom. Arch Intern Med 162(1):73\u201378. https:\/\/doi.org\/10.1001\/archinte.162.1.73","journal-title":"Arch Intern Med"},{"issue":"4","key":"5440_CR25","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1111\/j.1464-5491.2009.02698.x","volume":"26","author":"S Fosse","year":"2009","unstructured":"Fosse S, Hartemann-Heurtier A, Jacqueminet S, Ha Van G, Grimaldi A, Fagot-Campagna A (2009) Incidence and characteristics of lower limb amputations in people with diabetes. Diabet Med 26(4):391\u2013396. https:\/\/doi.org\/10.1111\/j.1464-5491.2009.02698.x","journal-title":"Diabet Med"},{"issue":"5","key":"5440_CR26","doi-asserted-by":"publisher","first-page":"860","DOI":"10.2337\/diacare.24.5.860","volume":"24","author":"JS Wrobel","year":"2001","unstructured":"Wrobel JS, Mayfield JA, Reiber GE (2001) Geographic variation of lower-extremity major amputation in individuals with and without diabetes in the Medicare population. Diabetes Care 24(5):860\u2013864. https:\/\/doi.org\/10.2337\/diacare.24.5.860","journal-title":"Diabetes Care"},{"issue":"11","key":"5440_CR27","doi-asserted-by":"publisher","first-page":"2363","DOI":"10.2337\/dc11-0807","volume":"34","author":"DJ Margolis","year":"2011","unstructured":"Margolis DJ, Hoffstad O, Nafash J et al (2011) Location, location, location: geographic clustering of lower-extremity amputation among Medicare beneficiaries with diabetes. Diabetes Care 34(11):2363\u20132367. https:\/\/doi.org\/10.2337\/dc11-0807","journal-title":"Diabetes Care"},{"issue":"7","key":"5440_CR28","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1007\/s00125-012-2468-6","volume":"55","author":"N Holman","year":"2012","unstructured":"Holman N, Young RJ, Jeffcoate WJ (2012) Variation in the recorded incidence of amputation of the lower limb in England. Diabetologia 55(7):1919\u20131925. https:\/\/doi.org\/10.1007\/s00125-012-2468-6","journal-title":"Diabetologia"},{"issue":"5","key":"5440_CR29","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.mcna.2013.03.008","volume":"97","author":"DJ Margolis","year":"2013","unstructured":"Margolis DJ, Jeffcoate W (2013) Epidemiology of foot ulceration and amputation: can global variation be explained? Med Clin North Am 97(5):791\u2013805. https:\/\/doi.org\/10.1016\/j.mcna.2013.03.008","journal-title":"Med Clin North Am"},{"issue":"10105","key":"5440_CR30","doi-asserted-by":"publisher","first-page":"e29","DOI":"10.1016\/s0140-6736(17)32401-7","volume":"390","author":"W Jeffcoate","year":"2017","unstructured":"Jeffcoate W, Barron E, Lomas J, Valabhji J, Young B (2017) Using data to tackle the burden of amputation in diabetes. Lancet 390(10105):e29\u2013e30. https:\/\/doi.org\/10.1016\/s0140-6736(17)32401-7","journal-title":"Lancet"},{"issue":"4","key":"5440_CR31","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1046\/j.1365-2168.2001.01738.x","volume":"88","author":"J Connelly","year":"2001","unstructured":"Connelly J, Airey M, Chell S (2001) Variation in clinical decision making is a partial explanation for geographical variation in lower extremity amputation rates. Br J Surg 88(4):529\u2013535. https:\/\/doi.org\/10.1046\/j.1365-2168.2001.01738.x","journal-title":"Br J Surg"}],"container-title":["Diabetologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-021-05440-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00125-021-05440-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00125-021-05440-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T00:09:18Z","timestamp":1648598958000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00125-021-05440-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,30]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["5440"],"URL":"https:\/\/doi.org\/10.1007\/s00125-021-05440-4","relation":{},"ISSN":["0012-186X","1432-0428"],"issn-type":[{"value":"0012-186X","type":"print"},{"value":"1432-0428","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,30]]},"assertion":[{"value":"3 November 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}