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We also gratefully acknowledge the participation and guidance of the American Indian partners associated with the clinical centre located at the University of Oklahoma Health Sciences Center, including members of the Absentee Shawnee Tribe, Cherokee Nation, Chickasaw Nation, Choctaw Nation of Oklahoma and Oklahoma City Area Indian Health Service. The opinions expressed in this paper are those of the authors and do not necessarily reflect the views of the respective Tribes and the Indian Health Service.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Acknowledgements"}},{"value":"Data from the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study (V4;\n                      \n                      \n                      ) reported here are available on request from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository (NIDDK-CR) Resources for Research (\n                      \n                      ).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"This work was completed with funding from the NIDDK and National Institutes of Health (NIH) Office of the Director through grants U01-DK61212, U01-DK61230, U01-DK61239, U01-DK61242 and U01-DK61254; the National Center for Research Resources General Clinical Research Center Program through grants M01-RR00036 (Washington University School of Medicine), M01-RR00043-45 (Children\u2019s Hospital Los Angeles), M01-RR00069 (University of Colorado Denver), M01-RR00084 (Children\u2019s Hospital of Pittsburgh), M01-RR01066 (Massachusetts General Hospital), M01-RR00125 (Yale University) and M01-RR14467 (University of Oklahoma Health Sciences Center); and the NCRR Clinical and Translational Science Awards through grants UL1-RR024134 (Children\u2019s Hospital of Philadelphia), UL1-RR024139 (Yale University), UL1-RR024153 (Children\u2019s Hospital of Pittsburgh), UL1-RR024989 (Case Western Reserve University), UL1-RR024992 (Washington University in St Louis), UL1-RR025758 (Massachusetts General Hospital) and UL1-RR025780 (University of Colorado Denver). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 relationships and activities"}},{"value":"KJN conceptualised the study, acquired and interpreted data, and led the writing of the manuscript. SAA, FB, SC, LCC, RF, KSH and MR acquired data. LE performed the analyses. MT and KC performed parts of the analyses. LE, MT, KC, SAA, FB, SC, LCC, RF, KSH and MR contributed to researching and interpretation of key content and edited the manuscript. All authors approved the final version to be published. LE is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Contribution statement"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}