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All other raw data are available from the corresponding author upon reasonable request.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}},{"value":"This work was supported by NIH grants HL148443 and HL135000 to SD, NIH grants NS116058 and AG057290 to FD, and American Heart Association grant 19TPA34850094 to SD.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 relationships and activities"}},{"value":"SV and VKP contributed to the experimental design, data acquisition and analysis, and editing and final approval of the manuscript. NV and DK participated in data acquisition, analysis and interpretation, and editing and final approval of the manuscript. FD contributed to the overall design of the project, data analysis and interpretation, and editing and final approval of the manuscript. SD contributed to the overall design of the project, data analysis and interpretation, writing, editing and final approval of the manuscript. SD is the guarantor.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Contribution statement"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}