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Iacocca Foundation. CT was supported by R01 HL155717. GLK was supported by the Dianne Nunnally Hoppes Fund, the Beatson Pledge Fund, the Beatson 50-Year Medalist Fund, R01 HL161864-01 and P30DK036836 (as part of the Joslin Diabetes Research Center Grant).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Funding"}},{"value":"RB has received support from Amgen Inc. and Novartis Inc. The rest of the authors declare no relationships or activities that might bias, or be perceived to bias, their work.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 relationships and activities"}},{"value":"MGY was responsible for study implementation and overall manuscript preparation. HS and SJ made substantial contributions to overall data analysis and interpretation, and contributed critically to manuscript writing. JG and EV made substantial contributions to participant recruitment and contributed critically to the acquisition and collection of clinical data and review of the manuscript. I-HW, TC, KP and QL made substantial contributions to the performance of assay tests, contributed critically to data collection, and reviewed the manuscript. WF and JS made substantial contributions to the acquisition and analysis of the participants\u2019 eye exams and contributed to data collection and manuscript writing. MJ, RB and CT made substantial contributions to the conception, design, acquisition, and analysis of cardiac imaging procedures, and critically reviewed and edited the manuscript. GLK was involved in the conception, design and overall study implementation, and co-wrote and reviewed the manuscript. All authors approved the final version of the manuscript for publication. GLK is the guarantor of this work and has full access to all of the data in the study, and takes responsibility for the integrity of the data and the accuracy of data analysis.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Contribution statement"}}]}}