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Work in the authors\u2019 laboratories is supported by the Swedish Medical Research Council (project no. 2022-00550 [ESV]), 2022-00811 [SC]); a Distinguished Investigator Grant \u2013 Endocrinology and Metabolism, Novo Nordisk Foundation (NNF22OC0072904 and project grant no. NNF25OC0104784 [ESV]); the Diabetes Foundation (DIA2024-860 [ESV], DIA2024-908 [SC]); and Karolinska Institutet KID funding (2023-0005 [ESV]). NT acknowledges support from a Karolinska Institute Research Foundation Grant (2024-03194) and special grants for young scientists.","order":1,"name":"Ethics","label":"Funding","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"ESV\u2019s department has received funding from Alnylam and Ferring. She has served as consultant and speaker for Alnylam and Exeltis. HH\u2019s institutions have received research funding from AstraZeneca, Echosens, Gilead, Intercept, MSD, Novo Nordisk, Takeda and Pfizer. He has served as consultant or speaker or on advisory boards for AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, GSK, Echosens, Ipsen, MSD and Novo Nordisk and has been part of hepatic events adjudication committees for Arrowhead, Boehringer Ingelheim, KOWA and GW Pharmaceuticals. NT serves as a national expert and member of the Swedish Institute for Standards (SIS). The authors declare that there are no other relationships or activities that might bias, or be perceived to bias, their work.","order":2,"name":"Ethics","label":"Authors\u2019 relationships and activities","group":{"name":"EthicsHeading","label":"Ethics"}},{"value":"All authors were responsible for drafting and critically reviewing the article for intellectual content. NT designed and prepared Figs\n                      \n                      and\n                      \n                      . All authors approved the final version of the article to be published.","order":3,"name":"Ethics","label":"Contribution statement","group":{"name":"EthicsHeading","label":"Ethics"}}]}}