{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T13:36:44Z","timestamp":1793453804309,"version":"4.5.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Soc Psychiatry Psychiatr Epidemiol"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s00127-012-0603-9","type":"journal-article","created":{"date-parts":[[2012,10,31]],"date-time":"2012-10-31T05:28:14Z","timestamp":1351661294000},"page":"927-933","source":"Crossref","is-referenced-by-count":19,"title":["Childhood and adult stressors and major depression risk: interpreting interactions with the sufficient-component cause model"],"prefix":"10.1007","volume":"48","author":[{"given":"Scott B.","family":"Patten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,11,1]]},"reference":[{"key":"603_CR1","volume-title":"Social origins of depression: a study of psychiatric disorder in women","author":"GW Brown","year":"1978","unstructured":"Brown GW, Harris TO (1978) Social origins of depression: a study of psychiatric disorder in women. Tavistock Publications, London"},{"key":"603_CR2","first-page":"173","volume-title":"Vulnerability","author":"GW Brown","year":"1978","unstructured":"Brown GW, Harris T (1978) Vulnerability. Social Origins of Depression. A Study of Psychiatric Disorder in Women. The Free Press, New York, pp 173\u2013191"},{"key":"603_CR3","first-page":"63","volume-title":"Measurement of Life Events","author":"GW Brown","year":"1978","unstructured":"Brown GW, Harris T (1978) Measurement of Life Events. Social Origins of Depression. A Study of Psychiatric Disorder in Women. The Free Press, New York, pp 63\u201381"},{"key":"603_CR4","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1017\/S0033291700011740","volume":"16","author":"GW Brown","year":"1986","unstructured":"Brown GW, Harris T (1986) Stressor, vulnerability and depression: a question of replication. Psychol Med 16:739\u2013744","journal-title":"Psychol Med"},{"key":"603_CR5","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jad.2008.01.015","volume":"110","author":"GW Brown","year":"2008","unstructured":"Brown GW, Craig TK, Harris TO, Handley RV (2008) Parental maltreatment and adulthood cohabiting partnerships: a life-course study of adult chronic depression\u20134. J Affect Disord 110:115\u2013125","journal-title":"J Affect Disord"},{"key":"603_CR6","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1007\/s00213-010-2118-y","volume":"214","author":"SE Claessens","year":"2011","unstructured":"Claessens SE, Daskalakis NP, van d V, Oitzl MS, de Kloet ER, Champagne DL (2011) Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences. Psychopharmacology 214:141\u2013154","journal-title":"Psychopharmacology"},{"key":"603_CR7","doi-asserted-by":"crossref","unstructured":"Colman I, Garad Y, Zeng Y, Naicker K, Weeks M, Patten SB, Jones PB, Thompson AH, Wild TC (2012) Stress and development of depression and heavy drinking in adulthood: moderating effects of childhood trauma. Soc Psychiatry Psychiatr Epidemiol. doi: 10.1007\/s00127-012-0531-8","DOI":"10.1007\/s00127-012-0531-8"},{"issue":"4","key":"603_CR8","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.biopsych.2011.10.021","volume":"71","author":"U Dannlowski","year":"2012","unstructured":"Dannlowski U, Stuhrmann A, Beutelmann V, Zwanzger P, Lenzen T, Grotegerd D, Domschke K, Hohoff C, Ohrmann P, Bauer J, Lindner C, Postert C, Konrad C, Arolt V, Heindel W, Suslow T, Kugel H (2012) Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging. Biol Psychiatry 71(4):286\u2013293","journal-title":"Biol Psychiatry"},{"key":"603_CR9","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1037\/0022-006X.68.5.782","volume":"68","author":"C Hammen","year":"2000","unstructured":"Hammen C, Henry R, Daley SE (2000) Depression and sensitization to stressors among young women as a function of childhood adversity. J Consult Clin Psychol 68:782\u2013787","journal-title":"J Consult Clin Psychol"},{"issue":"1","key":"603_CR10","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.expneurol.2011.10.032","volume":"233","author":"C Heim","year":"2012","unstructured":"Heim C, Binder EB (2012) Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp Neurol 233(1):102\u2013111","journal-title":"Exp Neurol"},{"key":"603_CR11","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1001\/archpsyc.1994.03950010008002","volume":"51","author":"RC Kessler","year":"1994","unstructured":"Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S, Wittchen HU, Kendler KS (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8\u201319","journal-title":"Arch Gen Psychiatry"},{"key":"603_CR12","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/mpr.47","volume":"7","author":"RC Kessler","year":"1998","unstructured":"Kessler RC, Andrews G, Mroczek D, Ustun B, Wittchen HU (1998) The World Health Organization composite international diagnostic interview short-form (CIDI-SF). Int J Methods Psychiatr Res 7:171\u2013185","journal-title":"Int J Methods Psychiatr Res"},{"key":"603_CR13","doi-asserted-by":"crossref","unstructured":"Kessler RC, Andrews G, Colpe LJ, Hiripi E, Mroczek DK, Normand SL (2002) Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med 32:959\u2013976","DOI":"10.1017\/S0033291702006074"},{"key":"603_CR14","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1017\/S0033291709992121","volume":"40","author":"KA McLaughlin","year":"2010","unstructured":"McLaughlin KA, Conron KJ, Koenen KC, Gilman SE (2010) Childhood adversity, adult stressful life events, and risk of past-year psychiatric disorder: a test of the stress sensitization hypothesis in a population-based sample of adults. Psychol Med 40:1647\u20131658","journal-title":"Psychol Med"},{"key":"603_CR15","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.molmed.2007.05.003","volume":"13","author":"MJ Meaney","year":"2007","unstructured":"Meaney MJ, Szyf M, Seckl JR (2007) Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol Med 13:269\u2013277","journal-title":"Trends Mol Med"},{"key":"603_CR16","doi-asserted-by":"crossref","unstructured":"Morgan Z, Brugha T, Fryers T, Stewart-Brown S (2012) The effects of parent-child relationships on later life mental health status in two national birth cohorts. Soc Psychiatry Psychiatr Epidemiol. doi: 10.1007\/s00127-012-0481-1","DOI":"10.1007\/s00127-012-0481-1"},{"key":"603_CR17","first-page":"5","volume-title":"Modern Epidemiology","author":"KJ Rothman","year":"2008","unstructured":"Rothman KJ, Greenland S, Poole C, Lash TL (2008) Causation and causal inference. In: Rothman KJ, Greenland S, Lash TL (eds) Modern Epidemiology. Lippincott Williams & Wilkins, Philadelphia, pp 5\u201331"},{"key":"603_CR18","unstructured":"Stata Corporation (2009) Stata, version 11.0. Stata Corporation, College Station, TX"},{"key":"603_CR19","volume-title":"Statistics Canada National Population Health Survey Household Component Cycle 1 to 7 (1994\/1995 to 2006\/2007) longitudinal documentation","author":"Statistics Canada","year":"2009","unstructured":"Statistics Canada (2009) Statistics Canada National Population Health Survey Household Component Cycle 1 to 7 (1994\/1995 to 2006\/2007) longitudinal documentation. Statistics Canada, Ottawa"},{"key":"603_CR20","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/em.20357","volume":"49","author":"M Szyf","year":"2008","unstructured":"Szyf M, McGowan P, Meaney MJ (2008) The social environment and the epigenome. Environ Mol Mutagen 49:46\u201360","journal-title":"Environ Mol Mutagen"},{"key":"603_CR21","doi-asserted-by":"crossref","first-page":"8507","DOI":"10.1073\/pnas.1003890107","volume":"107","author":"SE Taylor","year":"2010","unstructured":"Taylor SE (2010) Mechanisms linking early life stress to adult health outcomes. Proc Nat Acad Sci 107:8507\u20138512","journal-title":"Proc Nat Acad Sci"},{"key":"603_CR22","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1111\/j.1467-6494.2004.00300.x","volume":"72","author":"SE Taylor","year":"2004","unstructured":"Taylor SE, Lerner JS, Sage RM, Lehman BJ, Seeman TE (2004) Early environment, emotions, responses to stress, and health. J Pers 72:1365\u20131393","journal-title":"J Pers"},{"key":"603_CR23","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1017\/S0033291700004967","volume":"15","author":"C Tennant","year":"1985","unstructured":"Tennant C (1985) Female vulnerability to depression. Psychol Med 15:733\u2013737","journal-title":"Psychol Med"},{"key":"603_CR24","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/01.ede.0000260218.66432.88","volume":"18","author":"TJ Vanderweele","year":"2007","unstructured":"Vanderweele TJ, Robins JM (2007) The identification of synergism in the sufficient-component-cause framework. Epidemiology 18:329\u2013339","journal-title":"Epidemiology"},{"key":"603_CR25","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1037\/0003-066X.47.3.373","volume":"47","author":"JC Wakefield","year":"1992","unstructured":"Wakefield JC (1992) The concept of mental disorder. On the boundary between biological facts and social values. Am Psychol 47:373\u2013388","journal-title":"Am Psychol"},{"key":"603_CR26","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1001\/archpsyc.64.4.433","volume":"64","author":"JC Wakefield","year":"2007","unstructured":"Wakefield JC, Schmitz MF, First MB, Horwitz AV (2007) Extending the bereavement exclusion for major depression to other losses. Arch Gen Psychiatry 64:433\u2013440","journal-title":"Arch Gen Psychiatry"},{"key":"603_CR27","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nn1276","volume":"7","author":"IC Weaver","year":"2004","unstructured":"Weaver IC, Cervoni N, Champagne FA, D\u2019Alessio AC, Sharma S, Seckl JR, Dymov S, Szyf M, Meaney MJ (2004) Epigenetic programming by maternal behavior. Nat Neurosci 7:847\u2013854","journal-title":"Nat Neurosci"}],"container-title":["Social Psychiatry and Psychiatric Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-012-0603-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00127-012-0603-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-012-0603-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T08:07:11Z","timestamp":1558598831000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00127-012-0603-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,1]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["603"],"URL":"https:\/\/doi.org\/10.1007\/s00127-012-0603-9","relation":{},"ISSN":["0933-7954","1433-9285"],"issn-type":[{"value":"0933-7954","type":"print"},{"value":"1433-9285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,1]]}}}