{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T14:22:35Z","timestamp":1776694955049,"version":"3.51.2"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["H45E17000490001"],"award-info":[{"award-number":["H45E17000490001"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","award":["F52F16001420001"],"award-info":[{"award-number":["F52F16001420001"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002954","name":"Universit\u00e0 degli Studi di Milano - Bicocca","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100002954","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Soc Psychiatry Psychiatr Epidemiol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To measure indicators of timeliness and continuity of treatments on patients with schizophrenic disorder in \u2018real-life\u2019 practice, and to validate them through their relationship with relapse occurrences.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The target population was from four Italian regions overall covering 22 million beneficiaries of the NHS (37% of the entire Italian population). The cohort included 12,054 patients newly taken into care for schizophrenic disorder between January 2015 and June 2016. The self-controlled case series (SCCS) design was used to estimate the incidence rate ratio of relapse occurrences according to mental healthcare coverage.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Poor timeliness (82% and 33% of cohort members had not yet started treatment with psychosocial interventions and antipsychotic drug therapy within the first year after they were taken into care) and continuity (27% and 23% of patients were persistent with psychosocial interventions, and antipsychotic drug therapy within the first 2\u00a0years after starting the specific treatment) were observed. According to SCCS design, 4794 relapses occurred during 9430 PY (with incidence rate of 50.8 every 100 PY). Compared with periods not covered by mental healthcare, those covered by psychosocial intervention alone, antipsychotic drugs alone and by psychosocial intervention and antipsychotic drugs together were, respectively, associated with relapse rate reductions of 28% (95% CI 4\u201346%), 24% (17\u201330%) and 44% (32\u201353%).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Healthcare administrative data may contribute to monitor and to assess the effectiveness of a mental health system. Persistent use of both psychosocial intervention and antipsychotic drugs reduces risk of severe relapse.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00127-021-02114-9","type":"journal-article","created":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T05:03:06Z","timestamp":1623819786000},"page":"519-529","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Does the mental health system provide effective coverage to people with schizophrenic disorder? A self-controlled case series study in Italy"],"prefix":"10.1007","volume":"57","author":[{"given":"Giovanni","family":"Corrao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Barbato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"D\u2019Avanzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Di Fiandra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gaddini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2105-4572","authenticated-orcid":false,"given":"Matteo","family":"Monzio Compagnoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Saponaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Scondotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria D.","family":"Tozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia","family":"Carle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Lora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the \u201cQUADIM project\u201d, \u201cMonitoring, assessing care pathways (M. A. P.)\u201d working groups of the Italian Ministry of Health","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Di Fiandra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia","family":"Magliocchetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Lora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Barri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Saponaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Gaddini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Mattia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Scondotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Pollina Addario","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Berardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Di Giorgi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Corrao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Monzio Compagnoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelo","family":"Barbato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"D\u2019Avanzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Monti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Tozzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Ferrara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Flavia","family":"Carle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Bucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Casoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marianxhela","family":"Dajko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donata","family":"Bellentani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Carbone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Ceccolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"De Feo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Giordani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Lispi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosanna","family":"Mariniello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Medici","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Pisanti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Modesta","family":"Visca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rinaldo","family":"Zanini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Cantarutti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Corrao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Pugni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Rea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Davoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirko","family":"Di Martino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrizia","family":"Vittori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliana","family":"Vuillermin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Bernardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Fusciante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Belotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rossana","family":"De Palma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enza","family":"Di Felice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Di Lenarda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisa","family":"Prezza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danilo","family":"Fusco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adele","family":"Lallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Marinacci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Blaco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Leoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Lora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liana","family":"Spazzafumo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Pizzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Simiele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Massaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ettore","family":"Attolini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Lepore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vito","family":"Petrarolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Scondotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"De Luca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Francesconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Rizzuto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Avossa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Vigna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia","family":"Dondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nello","family":"Martini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella","family":"Pedrini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Piccinni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mimma","family":"Cosentino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Grazia","family":"Marvulli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Maggioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,16]]},"reference":[{"key":"2114_CR1","doi-asserted-by":"publisher","first-page":"731","DOI":"10.2471\/BLT.18.216002","volume":"96","author":"C Barbui","year":"2018","unstructured":"Barbui C, Papola D, Saraceno B (2018) The Italian mental health-care reform: public health lessons. Bull World Health Organ 96:731-731A","journal-title":"Bull World Health Organ"},{"key":"2114_CR2","first-page":"5","volume":"45","author":"A Lora","year":"2009","unstructured":"Lora A (2009) An overview of the mental health system in Italy. Ann Ist Super Sanit\u00e0 45:5\u201316","journal-title":"Ann Ist Super Sanit\u00e0"},{"key":"2114_CR3","first-page":"728","volume":"28","author":"A Lora","year":"2016","unstructured":"Lora A, Monzani E, Ibrahim B, Soranna D, Corrao G (2016) Routine quality care assessment of schizophrenic disorders using information systems. Int J Qual Health Care 28:728\u2013733","journal-title":"Int J Qual Health Care"},{"key":"2114_CR4","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1111\/j.1532-5415.2010.02726.x","volume":"58","author":"M Perry","year":"2010","unstructured":"Perry M, Draskovi\u0107 I, van Achterberg T, van Eijken M, Lucassen P, Vernooij-Dassen M et al (2010) Development and validation of quality indicators for dementia diagnosis and management in a primary care setting. J Am Geriatr Soc 58:557\u2013563","journal-title":"J Am Geriatr Soc"},{"key":"2114_CR5","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1186\/1471-2458-12-214","volume":"12","author":"S Lauriks","year":"2012","unstructured":"Lauriks S, Buster MC, de Wit MA, Arah OA, Klazinga NS (2012) Performance indicators for public mental healthcare: a systematic international inventory. BMC Public Health 12:214","journal-title":"BMC Public Health"},{"key":"2114_CR6","doi-asserted-by":"publisher","first-page":"205031211668651","DOI":"10.1177\/2050312116686516","volume":"5","author":"J Braithwaite","year":"2017","unstructured":"Braithwaite J, Hibbert P, Blakely B, Plumb J, Hannaford N, Long JC et al (2017) Health system frameworks and performance indicators in eight countries: a comparative international analysis. SAGE Open Med 5:2050312116686516","journal-title":"SAGE Open Med"},{"key":"2114_CR7","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1007\/s10488-017-0818-x","volume":"45","author":"E de Beurs","year":"2018","unstructured":"de Beurs E, Warmerdam EH, Oudejans SCC, Spits M, Dingemanse P, de Graaf SDD et al (2018) Treatment outcome, duration, and costs: a comparison of performance indicators using data from eight mental health care providers in the Netherlands. Adm Policy Ment Health 45:212\u2013223","journal-title":"Adm Policy Ment Health"},{"key":"2114_CR8","first-page":"083","volume":"3","author":"M Smith","year":"2018","unstructured":"Smith M, Butler A, Lesage A, Kurdyak P, Vigod S, Jones W et al (2018) A comparison of mental health performance indicators in Canada. Int J Popul Data Sci 3:083","journal-title":"Int J Popul Data Sci"},{"key":"2114_CR9","doi-asserted-by":"publisher","first-page":"e007140","DOI":"10.1136\/bmjopen-2014-007140","volume":"5","author":"G Corrao","year":"2015","unstructured":"Corrao G, Soranna D, Merlino L, Monzani E, Vigan\u00f2 C, Lora A (2015) Do patterns of mental healthcare predict treatment failure in young people with schizophrenia? Evidence from an Italian population-based cohort study. BMJ Open 5:e007140","journal-title":"BMJ Open"},{"key":"2114_CR10","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1093\/intqhc\/mzy186","volume":"31","author":"G Corrao","year":"2019","unstructured":"Corrao G, Rea F, Di Martino M, Lallo A, Davoli M, De Palma R, working group \u2018Monitoring and assessing diagnostic-therapeutic paths\u2019 of the Italian Heath Ministry et al (2019) Effectiveness of adherence to recommended clinical examinations of diabetic patients in preventing diabetes-related hospitalizations. Int J Qual Health Care 31:464\u2013472","journal-title":"Int J Qual Health Care"},{"key":"2114_CR11","doi-asserted-by":"publisher","first-page":"s37","DOI":"10.1192\/bjp.191.50.s37","volume":"191","author":"T Burns","year":"2007","unstructured":"Burns T (2007) Hospitalisation as an outcome measure in schizophrenia. Br J Psych 191:s37\u2013s41","journal-title":"Br J Psych"},{"key":"2114_CR12","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/1744-859X-12-32","volume":"12","author":"JM Olivares","year":"2013","unstructured":"Olivares JM, Sermon J, Hemels M, Schreiner A (2013) Definitions and drivers of relapse in patients with schizophrenia: a systematic literature review. Ann Gen Psych 12:32","journal-title":"Ann Gen Psych"},{"key":"2114_CR13","doi-asserted-by":"publisher","first-page":"i4515","DOI":"10.1136\/bmj.i4515","volume":"354","author":"I Petersen","year":"2016","unstructured":"Petersen I, Douglas I, Whitaker H (2016) Self controlled case series methods: an alternative to standard epidemiological study designs. BMJ 354:i4515","journal-title":"BMJ"},{"key":"2114_CR14","doi-asserted-by":"publisher","first-page":"l6987","DOI":"10.1136\/bmj.l6987","volume":"368","author":"H Forbes","year":"2020","unstructured":"Forbes H, Douglas I, Finn A, Breuer J, Bhaskaran K, Smeeth L et al (2020) Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. BMJ 368:l6987","journal-title":"BMJ"},{"issue":"346","key":"2114_CR15","doi-asserted-by":"publisher","first-page":"f1936","DOI":"10.1136\/bmj.f1936","volume":"12","author":"IJ Douglas","year":"2013","unstructured":"Douglas IJ, Langham J, Bhaskaran K, Brauer R, Smeeth L (2013) Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink. BMJ 12(346):f1936","journal-title":"BMJ"},{"key":"2114_CR16","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/0002-9343(80)90363-0","volume":"68","author":"RI Horwitz","year":"1980","unstructured":"Horwitz RI, Feinstein AR (1980) The problem of \u201cprotopathic bias\u201d in case-control studies. Am J Med 68:255\u2013258","journal-title":"Am J Med"},{"key":"2114_CR17","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jclinepi.2016.03.003","volume":"78","author":"A Arf\u00e8","year":"2016","unstructured":"Arf\u00e8 A, Corrao G (2016) The lag-time approach improved drug-outcome association estimates in presence of protopathic bias. J Clin Epidemiol 78:101\u2013107","journal-title":"J Clin Epidemiol"},{"key":"2114_CR18","doi-asserted-by":"publisher","first-page":"1768","DOI":"10.1002\/sim.2302","volume":"25","author":"HJ Whitaker","year":"2006","unstructured":"Whitaker HJ, Farrington CP, Spiessens B, Musonda P (2006) Tutorial in biostatistics: the self-controlled case series method. Stat Med 25:1768\u20131797","journal-title":"Stat Med"},{"key":"2114_CR19","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/1471-2288-12-9","volume":"12","author":"P Guyot","year":"2012","unstructured":"Guyot P, Ades AE, Ouwens MJ, Welton NJ (2012) Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves. BMC Med Res Methodol 12:9","journal-title":"BMC Med Res Methodol"},{"key":"2114_CR20","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","volume":"7","author":"R DerSimonian","year":"1986","unstructured":"DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177\u2013188","journal-title":"Control Clin Trials"},{"key":"2114_CR21","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","volume":"327","author":"JP Higgins","year":"2003","unstructured":"Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557\u2013560","journal-title":"BMJ"},{"key":"2114_CR22","first-page":"295","volume":"56","author":"T Tanahashi","year":"1978","unstructured":"Tanahashi T (1978) Health service coverage and its evaluation. Bull World Health Organ 56:295\u2013303","journal-title":"Bull World Health Organ"},{"key":"2114_CR23","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1017\/S2045796018000100","volume":"27","author":"S Pathare","year":"2018","unstructured":"Pathare S, Brazinova A, Levav I (2018) Care gap: a comprehensive measure to quantify unmet needs in mental health. Epidemiol Psychiatr Sci 27:463\u2013467","journal-title":"Epidemiol Psychiatr Sci"},{"key":"2114_CR24","doi-asserted-by":"publisher","first-page":"446","DOI":"10.1097\/NMD.0000000000000143","volume":"202","author":"A Lora","year":"2014","unstructured":"Lora A, Starace F, Di Munzio W, Fioritti A (2014) Italian community psychiatry in practice: description and comparison of three regional systems. J Nerv Ment Dis 202:446\u2013450","journal-title":"J Nerv Ment Dis"},{"key":"2114_CR25","unstructured":"Italian Ministry of Health. 3rd Italian Annual report on Mental Health, year 2017. http:\/\/www.salute.gov.it\/portale\/documentazione\/p6_2_2_1.jsp?lingua=italiano&id=2841"},{"key":"2114_CR26","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1007\/s00228-012-1298-2","volume":"68","author":"V Conti","year":"2012","unstructured":"Conti V, Lora A, Cipriani A, Fortino I, Merlino L, Barbui C (2012) Persistence with pharmacological treatment in the specialist mental healthcare of patients with severe mental disorders. Eur J Clin Pharmacol 68:1647\u20131655","journal-title":"Eur J Clin Pharmacol"},{"key":"2114_CR27","first-page":"741","volume":"22","author":"NJ Pauly","year":"2016","unstructured":"Pauly NJ, Talbert JC, Brown J (2016) Low-cost generic program use by medicare beneficiaries: implications for medication exposure misclassification in administrative claims data. J Manag Care Spec Pharm 22:741\u2013751","journal-title":"J Manag Care Spec Pharm"},{"key":"2114_CR28","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1007\/s00127-017-1465-y","volume":"53","author":"D Islek","year":"2018","unstructured":"Islek D, Kilic B, Akdede BB (2018) Out-of-pocket health expenditures in patients with bipolar disorder, anxiety, schizophrenia and other psychotic disorders: findings from a study in a psychiatry outpatient clinic in Turkey. Soc Psychiatry Psychiatr Epidemiol 53:151\u2013160","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"2114_CR29","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1093\/oxfordjournals.aje.a009002","volume":"144","author":"JP Mullooly","year":"1996","unstructured":"Mullooly JP, John P (1996) Misclassification model for person-time analysis of automated medical care databases. Am J Epidemiol 144:782\u2013792","journal-title":"Am J Epidemiol"}],"container-title":["Social Psychiatry and Psychiatric Epidemiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-021-02114-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00127-021-02114-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00127-021-02114-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,19]],"date-time":"2022-03-19T06:03:38Z","timestamp":1647669818000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00127-021-02114-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,16]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["2114"],"URL":"https:\/\/doi.org\/10.1007\/s00127-021-02114-9","relation":{},"ISSN":["0933-7954","1433-9285"],"issn-type":[{"value":"0933-7954","type":"print"},{"value":"1433-9285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,16]]},"assertion":[{"value":"2 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"GC received research support from the European Community (EC), the Italian Agency of Drug (AIFA), and the Italian Ministry for University and Research (MIUR). He took part to a variety of projects that were funded by pharmaceutical companies (i.e., Novartis, GSK, Roche, AMGEN and BMS). He also received honoraria as member of Advisory Board from Roche. No other potential conflicts of interest relevant to this article were disclosed.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}