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A series of multinomial logistic regression analyses examined the likelihood of child membership in one of three schizotypy profiles (<jats:italic>true schizotypy<\/jats:italic>, <jats:italic>introverted schizotypy<\/jats:italic>, and <jats:italic>affective schizotypy<\/jats:italic>) relative to the children showing <jats:italic>no risk<\/jats:italic>, according to maternal and paternal diagnoses of seven types of mental disorders.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>All types of parental mental disorders were associated with membership in all childhood schizotypy profiles. Children in the <jats:italic>true schizotypy<\/jats:italic> group were more than twice as likely as children in the <jats:italic>no risk<\/jats:italic> group to have a parent with any type of mental disorder (unadjusted odds ratio [OR]\u2009=\u20092.27, 95% confidence intervals [CI]\u2009=\u20092.01\u20132.56); those in the <jats:italic>affective<\/jats:italic> (OR\u2009=\u20091.54, 95% CI\u2009=\u20091.42\u20131.67) and <jats:italic>introverted schizotypy<\/jats:italic> profiles (OR\u2009=\u20091.39, 95% CI\u2009=\u20091.29\u20131.51) were also more likely to have been exposed to any parental mental disorder, relative to children showing <jats:italic>no risk<\/jats:italic>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Childhood schizotypy risk profiles appear not to be related specifically to familial liability for schizophrenia-spectrum disorders; this is consistent with a model where liability for psychopathology is largely general rather than specific to particular diagnostic categories.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00127-023-02455-7","type":"journal-article","created":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T22:22:40Z","timestamp":1679869360000},"page":"1637-1648","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Parental mental disorders and offspring schizotypy in middle childhood: an intergenerational record linkage study"],"prefix":"10.1007","volume":"58","author":[{"given":"Kirstie","family":"O\u2019Hare","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin R.","family":"Laurens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Watkeys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacy","family":"Tzoumakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberlie","family":"Dean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicity","family":"Harris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Linscott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaughan J.","family":"Carr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9361-4874","authenticated-orcid":false,"given":"Melissa J.","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"issue":"12","key":"2455_CR1","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1037\/h0041029","volume":"17","author":"PE Meehl","year":"1962","unstructured":"Meehl PE (1962) Schizotaxia, schizotypy, schizophrenia. 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