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We aimed to determine the risk of suicide and self-harm already in students entering different university programs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used national registers to identify 621,218 Swedish residents aged 18\u201339\u00a0years with registration for a university program 1993\u20132013. Outcomes were suicide and self-harm within three years. We applied logistic regression analyses to calculate odds ratios (OR) and 95% confidence intervals (CI) of risk of suicide and self-harm, with the Education program category as a reference. Results were adjusted for sex, age, time period and for history of hospitalization due to mental disorder or self-harm, as a measure of previous vulnerability. In the second step, we stratified results by sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a higher risk of suicide (OR 2.4) in female nursing students and natural science students (OR 4.2) and of self-harm in female and male Nursing\/Health care students (OR range 1.2 \u20131.7). Subcategorization into nursing students only strengthened the association with self-harm for both sexes. Prior vulnerability did not fully explain the increased risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The elevated risk of suicide in nursing and health care occupations partly has its onset in vulnerability factors present before or emerging during university studies. Increased efforts in identifying and treating mental disorders and preventing self-harm in university students could be an important step in preventing future suicides.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00127-023-02484-2","type":"journal-article","created":{"date-parts":[[2023,5,7]],"date-time":"2023-05-07T02:01:25Z","timestamp":1683424885000},"page":"1139-1149","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Risk of suicide and self-harm in university students entering different university programs \u2013 a national register-based cohort study in Sweden"],"prefix":"10.1007","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6156-5097","authenticated-orcid":false,"given":"Christine Takami","family":"Lageborn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Bjureberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Runeson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jette","family":"M\u00f6ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rickard","family":"Ljung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Dahlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,7]]},"reference":[{"issue":"8","key":"2484_CR1","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1017\/S0033291707000487","volume":"37","author":"E Agerbo","year":"2007","unstructured":"Agerbo E, Gunnell D, Bonde JP, Mortensen PB, Nordentoft M (2007) Suicide and occupation: the impact of socio-economic, demographic and psychiatric differences. 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The views expressed in this paper do not necessarily represent the views of the Government agency. All other authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Regional Ethical Review Board in Stockholm (case number 2012-1669-31\/5) and (case number 2016\/2021-32).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"SAS and STATA syntax is available upon request.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}