{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:10:29Z","timestamp":1783721429459,"version":"3.55.0"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"name":"European Union and French Development Agency","award":["FOOD\/2019\/412-132"],"award-info":[{"award-number":["FOOD\/2019\/412-132"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Environ Contam Toxicol"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00128-025-04120-y","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:23:30Z","timestamp":1760621010000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Genotoxicity Risk Assessment in Nile tilapia (Oreochromis niloticus) from a Hatchery Exposed to Pesticides in the Haut-Sassandra Region, C\u00f4te d\u2019Ivoire"],"prefix":"10.1007","volume":"115","author":[{"given":"Antoine K.","family":"Kouadio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles K.","family":"Boussou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Canonne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliette","family":"Gaillard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1531-0362","authenticated-orcid":false,"given":"Simon","family":"Pouil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2624-0929","authenticated-orcid":false,"given":"Elodie","family":"Pepey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"4120_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2021.109147","volume":"249","author":"\u00dc Acar","year":"2021","unstructured":"Acar \u00dc, Inanan BE, Navruz FZ, Y\u0131lmaz S (2021) Alterations in blood parameters, DNA damage, oxidative stress and antioxidant enzymes and immune-related genes expression in Nile tilapia (Oreochromis niloticus) exposed to glyphosate-based herbicide. Comp Biochem Physiol C Toxicol Pharmacol 249:109147. https:\/\/doi.org\/10.1016\/j.cbpc.2021.109147","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"4120_CR2","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.chemosphere.2011.02.025","volume":"84","author":"MK Ahmed","year":"2011","unstructured":"Ahmed MK, Habibullah-Al-Mamun M, Hossain MA, Arif M, Parvin E, Akter MS, Khan MS, Islam MM (2011) Assessing the genotoxic potentials of arsenic in tilapia (Oreochromis mossambicus) using alkaline comet assay and micronucleus test. Chemosphere 84:143\u2013149. https:\/\/doi.org\/10.1016\/j.chemosphere.2011.02.025","journal-title":"Chemosphere"},{"key":"4120_CR3","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1590\/S1415-47572014000100016","volume":"37","author":"C Alvarez-Moya","year":"2014","unstructured":"Alvarez-Moya C, Silva RM, Valdez Ram\u00edrez C, Gallardo DG, S\u00e1nchez LR, Aguirre CA, Velasco AF (2014) Comparison of the in vivo and in vitro genotoxicity of glyphosate isopropylamine salt in three different organisms. Genet Mol Biol 37:105\u2013110. https:\/\/doi.org\/10.1590\/S1415-47572014000100016","journal-title":"Genet Mol Biol"},{"key":"4120_CR4","doi-asserted-by":"publisher","first-page":"389","DOI":"10.19044\/esj.2017.v13n6p389","volume":"13","author":"AF Amian","year":"2017","unstructured":"Amian AF, Wandan EN, Bl\u00e9 MC, Vanga AF, Assi-Kaudhjis JP (2017) \u00c9tude des d\u00e9terminants socio-\u00e9conomiques et techniques de la pisciculture extensive en C\u00f4te d\u2019Ivoire. Eur Sci J 13:389\u2013409. https:\/\/doi.org\/10.19044\/esj.2017.v13n6p389","journal-title":"Eur Sci J"},{"key":"4120_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5620\/eaht.2022012","volume":"37","author":"OA Aribisala","year":"2022","unstructured":"Aribisala OA, Sogbanmu TO, Kemabonta KA (2022) Genotoxic, biochemical and histological biomarkers of subacute concentrations of paraquat and glyphosate in Nile tilapia. Environ Anal Health Toxicol 37:1\u201313. https:\/\/doi.org\/10.5620\/eaht.2022012","journal-title":"Environ Anal Health Toxicol"},{"key":"4120_CR6","first-page":"4271","volume":"59","author":"JBLF Avit","year":"2012","unstructured":"Avit JBLF, Boni KY, Kouassi NC, Konan KKF, Assemian O, Alloukou JR (2012) Conditions \u00e9cologiques de production de fingerlings de Oreochromis niloticus (Linn\u00e9, 1758) en association avec le riz Wita 12 en \u00e9tang. J Appl Biosci 59:4271\u20134285","journal-title":"J Appl Biosci"},{"key":"4120_CR7","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s00204-013-1070-0","volume":"87","author":"A Azqueta","year":"2013","unstructured":"Azqueta A, Collins AR (2013) The essential comet assay: a comprehensive guide to measuring DNA damage and repair. Arch Toxicol 87:949\u2013968. https:\/\/doi.org\/10.1007\/s00204-013-1070-0","journal-title":"Arch Toxicol"},{"key":"4120_CR8","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.gecco.2016.08.009","volume":"8","author":"YSS Barima","year":"2016","unstructured":"Barima YSS, Kouakou ATM, Bamba I, Sagne YC, Godron M, Andrieu J, Bogaert J (2016) Cocoa crops are destroying the forest reserves of the classified forest of Haut-Sassandra (Ivory Coast). Glob Ecol Conserv 8:85\u201398. https:\/\/doi.org\/10.1016\/j.gecco.2016.08.009","journal-title":"Glob Ecol Conserv"},{"key":"4120_CR9","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.mrgentox.2008.06.010","volume":"655","author":"DGSM Cavalcante","year":"2008","unstructured":"Cavalcante DGSM, Martinez CBR, Sofia SH (2008) Genotoxic effects of Roundup on the fish Prochilodus lineatus. Mutat Res Genet Toxicol Environ Mutagen 655:41\u201346. https:\/\/doi.org\/10.1016\/j.mrgentox.2008.06.010","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"4120_CR10","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1093\/mutage\/gem012","volume":"22","author":"T Cava\u015f","year":"2007","unstructured":"Cava\u015f T, K\u00f6nen S (2007) Detection of cytogenetic and DNA damage in peripheral erythrocytes of goldfish (Carassius auratus) exposed to a glyphosate formulation using the micronucleus test and the comet assay. Mutagenesis 22:263\u2013268. https:\/\/doi.org\/10.1093\/mutage\/gem012","journal-title":"Mutagenesis"},{"key":"4120_CR11","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1080\/10454431003736524","volume":"22","author":"S Chainark","year":"2010","unstructured":"Chainark S, Boyd CE (2010) Water and sediment quality, phytoplankton communities, and channel catfish production in sodium nitrate-treated ponds. J Appl Aquac 22:171\u2013185. https:\/\/doi.org\/10.1080\/10454431003736524","journal-title":"J Appl Aquac"},{"key":"4120_CR12","volume-title":"Statistical power analysis for the behavioral sciences","author":"J Cohen","year":"1988","unstructured":"Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Lawrence Erlbaum Associates, Hillsdale","edition":"2"},{"key":"4120_CR13","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1385\/MB:26:3:249","volume":"26","author":"AR Collins","year":"2004","unstructured":"Collins AR (2004) The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 26:249\u2013261. https:\/\/doi.org\/10.1385\/MB:26:3:249","journal-title":"Mol Biotechnol"},{"key":"4120_CR14","unstructured":"CPCO (2019) Informations g\u00e9n\u00e9rales relatives aux p\u00eaches en C\u00f4te d\u2019Ivoire. Comit\u00e9 des P\u00eaches du Centre-Ouest du Golfe de Guin\u00e9e. https:\/\/fcwc-fish.org\/a-propos-de-nous\/etats-membres\/cote-divoire?lang=fr"},{"key":"4120_CR15","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.aquatox.2010.11.017","volume":"101","author":"A Devaux","year":"2011","unstructured":"Devaux A, Fiat L, Gillet C, Bony S (2011) Reproduction impairment following paternal genotoxin exposure in brown trout (Salmo trutta) and Arctic charr (Salvelinus alpinus). Aquat Toxicol 101:405\u2013411. https:\/\/doi.org\/10.1016\/j.aquatox.2010.11.017","journal-title":"Aquat Toxicol"},{"key":"4120_CR16","unstructured":"Trend Economy (2022) Annual international trade statistics by country (HS): Imports structure to C\u00f4te d\u2019Ivoire in 2020. Trend Economy. https:\/\/trendeconomy.com\/data\/h2\/CoteDIvoire\/TOTAL"},{"key":"4120_CR17","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1007\/s00128-022-03611-6","volume":"109","author":"IM El-Garawani","year":"2022","unstructured":"El-Garawani IM, Khallaf EA, Alne-Na-Ei AA, Elgendy RG, Sobhy HM, Khairallah A, Hathout HM, Malhat F, Nofal AE (2022) The effect of neonicotinoids exposure on Oreochromis niloticus: histopathological alterations and genotoxicity. Bull Environ Contam Toxicol 109:1001\u20131009. https:\/\/doi.org\/10.1007\/s00128-022-03611-6","journal-title":"Bull Environ Contam Toxicol"},{"key":"4120_CR18","doi-asserted-by":"publisher","first-page":"63747","DOI":"10.1007\/s11356-024-35420-1","volume":"31","author":"KS El-Gendy","year":"2024","unstructured":"El-Gendy KS, Mosallam EM, Abd El Kader AS, Radwan MA (2024) Sole and co exposure toxicity of commercial formulations ethoprophos and bispyribac sodium to Oreochromis niloticus: assessment of oxidative stress, genotoxicity, and gill ultrastructure. Environ Sci Pollut 31:63747\u201363763. https:\/\/doi.org\/10.1007\/s11356-024-35420-1","journal-title":"Environ Sci Pollut"},{"key":"4120_CR19","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1007\/s10695-025-01490-2","volume":"51","author":"KS El-Gendy","year":"2025","unstructured":"El-Gendy KS, Mosallam EM, Abd El Kader AS, Abdel Monem AI, Radwan MA (2025) Single and joint toxicity of ethoprophos and bispyribac-sodium to Oreochromis niloticus: biochemical and genotoxic responses. Fish Physiol Biochem 51:86. https:\/\/doi.org\/10.1007\/s10695-025-01490-2","journal-title":"Fish Physiol Biochem"},{"key":"4120_CR20","unstructured":"Failler P, El Ayoubi H, Konan A (2014) Industrie des p\u00eaches et de l'aquaculture en C\u00f4te d\u2019Ivoire. In\u00a0: Conf\u00e9rence Minist\u00e9rielle sur la Coop\u00e9ration Halieutique entre les \u00c9tats Africains Riverains de l\u2019Oc\u00e9an Atlantique"},{"key":"4120_CR21","unstructured":"FAO (2022) FISH4ACP: Unlocking the potential of sustainable fisheries and aquaculture in Africa, the Caribbean and the Pacific: C\u00f4te d\u2019Ivoire. Food and Agriculture Organization of the United Nations."},{"key":"4120_CR22","unstructured":"FAO (2024) FishStatJ: Software for fishery statistical time series. Food and Agriculture Organization of the United Nations"},{"key":"4120_CR23","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.mrrev.2008.03.001","volume":"681","author":"G Frenzilli","year":"2009","unstructured":"Frenzilli G, Nigro M, Lyons BP (2009) The comet assay for the evaluation of genotoxic impact in aquatic environments. Mutat Res Rev Mutat Res 681:80\u201392. https:\/\/doi.org\/10.1016\/j.mrrev.2008.03.001","journal-title":"Mutat Res Rev Mutat Res"},{"key":"4120_CR24","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.redox.2013.12.020","volume":"2","author":"BM Gyori","year":"2014","unstructured":"Gyori BM, Venkatachalam G, Thiagarajan PS, Hsu D, Clement MV (2014) Opencomet: an automated tool for comet assay image analysis. Redox Biol 2:457\u2013465. https:\/\/doi.org\/10.1016\/j.redox.2013.12.020","journal-title":"Redox Biol"},{"key":"4120_CR25","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1007\/s13530-020-00042-w","volume":"12","author":"AMM Haredi","year":"2020","unstructured":"Haredi AMM, Mourad M, Tanekhy M, Wassif E, Abdel-Tawab HS (2020) Lake Edku pollutants induced biochemical and histopathological alterations in muscle tissues of Nile tilapia (Oreochromis niloticus). Toxicol Environ Health Sci 12:247\u2013255. https:\/\/doi.org\/10.1007\/s13530-020-00042-w","journal-title":"Toxicol Environ Health Sci"},{"key":"4120_CR26","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1093\/mutage\/gen014","volume":"23","author":"AN Jha","year":"2008","unstructured":"Jha AN (2008) Ecotoxicological applications and significance of the comet assay. Mutagenesis 23:207\u2013221. https:\/\/doi.org\/10.1093\/mutage\/gen014","journal-title":"Mutagenesis"},{"key":"4120_CR27","first-page":"20","volume":"21","author":"NKC Kouadio","year":"2022","unstructured":"Kouadio NKC, Koulibaly A, N\u2019guessan KR, Boko BB, Dramane KB, Diomande VP, Diaby F (2022) Connaissance des plantes m\u00e9dicinales et lieux d\u2019approvisionnement d\u2019int\u00e9r\u00eat: Cas des producteurs de cacao et leurs familles de la localit\u00e9 de Gonat\u00e9 (Centre-Ouest, C\u00f4te d\u2019Ivoire). Rev RAMReS S\u00e9r Pharmacop\u00e9e M\u00e9d Tradit 21:20\u201332","journal-title":"Rev RAMReS S\u00e9r Pharmacop\u00e9e M\u00e9d Tradit"},{"key":"4120_CR28","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.mrgentox.2006.03.002","volume":"605","author":"TS Kumaravel","year":"2006","unstructured":"Kumaravel TS, Jha AN (2006) Reliable comet assay measurements for detecting DNA damage induced by ionizing radiation and chemicals. Mutat Res Genet Toxicol Environ Mutagen 605:7\u201316. https:\/\/doi.org\/10.1016\/j.mrgentox.2006.03.002","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"4120_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4000\/tem.2745","volume":"25\u201326","author":"F Laurent","year":"2015","unstructured":"Laurent F (2015) L\u2019\u00e9volution des pratiques agricoles face aux enjeux de la qualit\u00e9 de l\u2019eau\u202f: Le bassin de l\u2019Oudon (France). Territoire Mouvement Rev Geogr Amenag 25\u201326:1\u201315. https:\/\/doi.org\/10.4000\/tem.2745","journal-title":"Territoire Mouvement Rev Geogr Amenag"},{"key":"4120_CR30","unstructured":"MIPARH (2004) Annuaire des statistiques de l\u2019aquaculture et des p\u00eaches. Minist\u00e8re des Ressources Animales et Halieutiques"},{"key":"4120_CR31","unstructured":"MIPARH (2014) Plan strat\u00e9gique de d\u00e9veloppement de l\u2019\u00e9levage, de la p\u00eache et de l\u2019aquaculture en C\u00f4te d\u2019Ivoire (PSDEPA 2014\u20132020). Tome I : Diagnostic \u2013 Strat\u00e9gie de D\u00e9veloppement \u2013 Orientations. Minist\u00e8re des Ressources Animales et Halieutiques"},{"key":"4120_CR32","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1006\/eesa.1998.1666","volume":"41","author":"CL Mitchelmore","year":"1998","unstructured":"Mitchelmore CL, Birmelin C, Livingstone DR, Chipman JK (1998) Detection of DNA strand breaks in isolated mussel (Mytilus edulis) digestive gland cells using the \u201ccomet\u201d assay. Ecotoxicol Environ Saf 41:51\u201358. https:\/\/doi.org\/10.1006\/eesa.1998.1666","journal-title":"Ecotoxicol Environ Saf"},{"key":"4120_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2021.736386","volume":"535","author":"NAG Moyo","year":"2021","unstructured":"Moyo NAG, Rapatsa MM (2021) A review of the factors affecting tilapia aquaculture production in Southern Africa. Aquaculture 535:736386. https:\/\/doi.org\/10.1016\/j.aquaculture.2021.736386","journal-title":"Aquaculture"},{"key":"4120_CR34","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.aquaculture.2014.02.004","volume":"426\u2013427","author":"AM Nasr-Allah","year":"2014","unstructured":"Nasr-Allah AM, Dickson MW, Al-Kenawy DAR, Ahmed MFM, El-Naggar GO (2014) Technical characteristics and economic performance of commercial tilapia hatcheries applying different management systems in Egypt. Aquaculture 426\u2013427:222\u2013230. https:\/\/doi.org\/10.1016\/j.aquaculture.2014.02.004","journal-title":"Aquaculture"},{"key":"4120_CR35","unstructured":"Niamien KHJ (2019) Pisciculture et d\u00e9veloppement rural dans le quart Sud-Ouest de la C\u00f4te d\u2019Ivoire. Universit\u00e9 Alassane Ouattara"},{"key":"4120_CR36","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/nprot.2006.5","volume":"1","author":"PL Olive","year":"2006","unstructured":"Olive PL, Ban\u00e1th JP (2006) The comet assay: a method to measure DNA damage in individual cells. Nat Protoc 1:23\u201329. https:\/\/doi.org\/10.1038\/nprot.2006.5","journal-title":"Nat Protoc"},{"key":"4120_CR37","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1002\/tox.20373","volume":"23","author":"AGM Osman","year":"2008","unstructured":"Osman AGM, Mekkawy IA, Verreth J, Wuertz S, Kloas W, Kirschbaum F (2008) Monitoring of DNA breakage in embryonic stages of the African catfish (Clarias gariepinus) after exposure to lead nitrate using alkaline comet assay. Environ Toxicol 23:679\u2013687. https:\/\/doi.org\/10.1002\/tox.20373","journal-title":"Environ Toxicol"},{"key":"4120_CR38","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.mrgentox.2012.02.013","volume":"747","author":"AGM Osman","year":"2012","unstructured":"Osman AGM, Abuel-Fadl KY, Kloas W (2012) In situ evaluation of the genotoxic potential of the river Nile: II. Detection of DNA strand-breakage and apoptosis in Oreochromis niloticus and Clarias gariepinus. Mutat Res Genet Toxicol Environ Mutagen 747:14\u201321. https:\/\/doi.org\/10.1016\/j.mrgentox.2012.02.013","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"4120_CR39","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.mrgentox.2011.09.011","volume":"726","author":"AK Pandey","year":"2011","unstructured":"Pandey AK, Nagpure NS, Trivedi SP, Kumar R, Kushwaha B (2011) Profenofos induced DNA damage in freshwater fish, Channa punctatus (Bloch) using alkaline single cell gel electrophoresis. Mutat Res Genet Toxicol Environ Mutagen 726:209\u2013214. https:\/\/doi.org\/10.1016\/j.mrgentox.2011.09.011","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"4120_CR40","doi-asserted-by":"publisher","first-page":"1266","DOI":"10.1002\/etc.5605","volume":"42","author":"E Pepey","year":"2023","unstructured":"Pepey E, Con\u00e9j\u00e9ro G, Ndrianaivo EN, Verdeil JL, Mortillaro JM, Boggio D, Raliniaina M, Pouil S (2023) Cytogenotoxicity screening of urban and rural marshes: an integrated in vivo approach coupling fish- and plant-based tests adapted for low-income countries. Environ Toxicol Chem 42:1266\u20131275. https:\/\/doi.org\/10.1002\/etc.5605","journal-title":"Environ Toxicol Chem"},{"key":"4120_CR41","unstructured":"R Development Core Team (2022) R: A language and environment for statistical computing. R Foundation for Statistical Computing"},{"key":"4120_CR42","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2023.106738","volume":"265","author":"ANA Rahman","year":"2023","unstructured":"Rahman ANA, Altohamy DE, Elshopakey GE, Abdelwarith AA, Younis EM, Elseddawy NM, Elgamal A, Bazeed MS, Khamis T, Davies SJ, Ibrahim RE (2023) Potential role of dietary Boswellia serrata resin against mancozeb fungicide-induced immune-antioxidant suppression, histopathological alterations, and genotoxicity in Nile tilapia (Oreochromis niloticus). Aquat Toxicol 265:106738. https:\/\/doi.org\/10.1016\/j.aquatox.2023.106738","journal-title":"Aquat Toxicol"},{"key":"4120_CR43","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.cbi.2016.06.003","volume":"254","author":"V Rizzati","year":"2016","unstructured":"Rizzati V, Briand O, Guillou H, Gamet-Payrastre L (2016) Effects of pesticide mixtures in human and animal models: an update of the recent literature. Chem Biol Interact 254:231\u2013246. https:\/\/doi.org\/10.1016\/j.cbi.2016.06.003","journal-title":"Chem Biol Interact"},{"key":"4120_CR44","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.ecoenv.2009.10.002","volume":"73","author":"S S\u00e1nchez-Gal\u00e1n","year":"2010","unstructured":"S\u00e1nchez-Gal\u00e1n S, Linde AR, Izquierdo JI, Garc\u00eda-V\u00e1zquez E (2010) Micronuclei and other nuclear abnormalities in wild fish from the River Cinca (Spain). Ecotoxicol Environ Saf 73:318\u2013325. https:\/\/doi.org\/10.1016\/j.ecoenv.2009.10.002","journal-title":"Ecotoxicol Environ Saf"},{"key":"4120_CR45","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1002\/tox.22055","volume":"31","author":"T Santos","year":"2016","unstructured":"Santos T, Joyeux A, Palluel O, Palos-Ladeiro M, Besnard A, Blanchard C, Porcher JM, Bony S, Devaux A, Sanchez W (2016) Characterization of a genotoxicity biomarker in three-spined stickleback (Gasterosteus aculeatus L.): biotic variability and integration in a battery of biomarkers for environmental monitoring. Environ Toxicol 31:415\u2013426. https:\/\/doi.org\/10.1002\/tox.22055","journal-title":"Environ Toxicol"},{"key":"4120_CR46","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/978-81-322-2271-2_20","volume-title":"Advances in Marine and Brackishwater Aquaculture","author":"R Saraswathy","year":"2015","unstructured":"Saraswathy R, Muralidhar M, Sundaray JK, Lalitha N, Kumararaja P (2015) Water quality management in fish hatchery and grow-out systems. In: Santhanam P, Thirunavukkarasu AR, Perumal P (eds) Advances in Marine and Brackishwater Aquaculture. Springer, Singapore, pp 217\u2013225. https:\/\/doi.org\/10.1007\/978-81-322-2271-2_20"},{"key":"4120_CR47","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/0014-4827(88)90265-0","volume":"175","author":"NP Singh","year":"1988","unstructured":"Singh NP, McCoy MT, Tice RR, Schneider EL (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184\u2013191. https:\/\/doi.org\/10.1016\/0014-4827(88)90265-0","journal-title":"Exp Cell Res"},{"key":"4120_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2024.104377","volume":"106","author":"O Temiz","year":"2024","unstructured":"Temiz O, Karg\u0131n D (2024) Physiological responses of oxidative damage, genotoxicity, and hematological parameters of the toxic effect of neonicotinoid-thiamethoxam in Oreochromis niloticus. Environ Toxicol Pharmacol 106:104377. https:\/\/doi.org\/10.1016\/j.etap.2024.104377","journal-title":"Environ Toxicol Pharmacol"},{"key":"4120_CR49","first-page":"191","volume":"34","author":"CZ Ue Bi","year":"2021","unstructured":"Ue Bi CZ, Ouattara NI, Bert\u00e9 S, Kamagate B (2021) Performances zootechniques des alevins de trois souches du tilapia du Nil (Oreochromis niloticus L., 1758) du paysage aquacole de la C\u00f4te d\u2019Ivoire \u00e9lev\u00e9es en happa implant\u00e9 dans un \u00e9tang. Agron Afr 34:191\u2013198","journal-title":"Agron Afr"},{"key":"4120_CR50","doi-asserted-by":"publisher","first-page":"109336","DOI":"10.1016\/j.cbpc.2022.109336","volume":"257","author":"SK Veedu","year":"2022","unstructured":"Veedu SK, Ayyasamy G, Tamilselvan H, Ramesh M (2022) Single and joint toxicity assessment of acetamiprid and thiamethoxam neonicotinoids pesticides on biochemical indices and antioxidant enzyme activities of a freshwater fish Catla catla. Comp Biochem Physiol C Toxicol Pharmacol 257:109336","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"4120_CR51","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1016\/j.toxrep.2022.03.031","volume":"9","author":"P Vijitkul","year":"2022","unstructured":"Vijitkul P, Kongsema M, Toommakorn T, Bullangpoti V (2022) Investigation of genotoxicity, mutagenicity, and cytotoxicity in erythrocytes of Nile tilapia (Oreochromis niloticus) after fluoxetine exposure. Toxicol Rep 9:588\u2013596. https:\/\/doi.org\/10.1016\/j.toxrep.2022.03.031","journal-title":"Toxicol Rep"},{"key":"4120_CR52","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.mrgentox.2006.11.011","volume":"628","author":"G Wirzinger","year":"2007","unstructured":"Wirzinger G, Weltje L, Gercken J, Sordyl H (2007) Genotoxic damage in field-collected three-spined sticklebacks (Gasterosteus aculeatus L.): a suitable biomonitoring tool? Mutat Res Genet Toxicol Environ Mutagen 628:19\u201330. https:\/\/doi.org\/10.1016\/j.mrgentox.2006.11.011","journal-title":"Mutat Res Genet Toxicol Environ Mutagen"},{"key":"4120_CR53","unstructured":"Yao AB (2015) \u00c9valuation de potentialit\u00e9s en eau du bassin versant de la Lobo en vue d\u2019une gestion rationnelle (centre-ouest de la C\u00f4te d\u2019Ivoire). Universit\u00e9 Nangui Abrogoua"}],"container-title":["Bulletin of Environmental Contamination and Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00128-025-04120-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00128-025-04120-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00128-025-04120-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:31:55Z","timestamp":1762957915000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00128-025-04120-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,16]]},"references-count":53,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["4120"],"URL":"https:\/\/doi.org\/10.1007\/s00128-025-04120-y","relation":{},"ISSN":["0007-4861","1432-0800"],"issn-type":[{"value":"0007-4861","type":"print"},{"value":"1432-0800","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,16]]},"assertion":[{"value":"18 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that there is no conflict of interest concerning this research.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"53"}}