{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T08:12:50Z","timestamp":1778055170807,"version":"3.51.4"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T00:00:00Z","timestamp":1774656000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Bull Environ Contam Toxicol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00128-026-04227-w","type":"journal-article","created":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T10:26:36Z","timestamp":1774693596000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Emerging Substances of Concern (ESoCs) to Consider as Priorities for Monitoring in Drinking Water and Municipal Wastewater"],"prefix":"10.1007","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7332-276X","authenticated-orcid":false,"given":"Viviane","family":"Yargeau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris D.","family":"Metcalfe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,28]]},"reference":[{"key":"4227_CR1","doi-asserted-by":"publisher","first-page":"114092","DOI":"10.1016\/j.envpol.2020.114092","volume":"261","author":"JK Challis","year":"2020","unstructured":"Challis JK, Almirall XO, Helm PA, Wong CS (2020) Performance of the organic-diffusive gradients in thin-films passive sampler for measurement of target and suspect wastewater contaminants. Environ Pollut 261:114092","journal-title":"Environ Pollut"},{"key":"4227_CR2","unstructured":"Dieter HH, Grenzwerte, Leitwerte O (2011) Ma\u00dfnahmenwerte - Aktuelle Definitionen und H\u00f6chstwerte. Umweltbundesamt. German Environmental Agency, Dessau-Ro\u00dflau, Germany, 10 p. Available on-line at: http:\/\/www.umweltbundesamt.de"},{"key":"4227_CR3","unstructured":"Drewes JE, Anderson P, Denslow N, Muir DCG, Olivieri A, Schlenk D, Snyder SA Monitoring strategies for constituents of emerging concern (CECs) in California\u2019s aquatic ecosystems: recommendations of a science advisory panel, technical report 1302, 2023, Southern California Coastal Water Research Project, San Diego, CA, USA, 363 p. Available on-line at: https:\/\/www.waterboards.ca.gov\/water_issues\/programs\/cec\/docs\/ecopanel-finalreport-SCCWRP-TR1302.pdf"},{"key":"4227_CR4","unstructured":"Environment and Climate Change Canada Toxic Substances List, Schedule 1. Available on-line at: https:\/\/www.canada.ca\/en\/environment-climate-change\/services\/canadian-environmental-protection-act-registry\/substances-list\/toxic\/schedule-1.html"},{"key":"4227_CR5","unstructured":"European Commission. Commission Implementing Decision (EU) 2022\/1307 of 22 July 2022 establishing a watch list of substances for Union-wide monitoring in the field of water policy pursuant to Directive 2008\/105\/EC of the European Parliament and of the Council (notified under document C(2022) 5098) (2022) Available on-line at: https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=CELEX:32022D1307"},{"key":"4227_CR6","doi-asserted-by":"publisher","first-page":"122293","DOI":"10.1016\/j.talanta.2021.122293","volume":"230","author":"E Eysseric","year":"2021","unstructured":"Eysseric E, Beaudry F, Gagnon C, Segura PA (2021) Non-targeted screening of trace organic contaminants in surface waters by a multi-tool approach based on combinatorial analysis of tandem mass spectra and open access databases. Talanta 230:122293","journal-title":"Talanta"},{"key":"4227_CR7","doi-asserted-by":"publisher","first-page":"153540","DOI":"10.1016\/j.scitotenv.2022.153540","volume":"822","author":"E Eysseric","year":"2022","unstructured":"Eysseric E, Gagnon C, Segura PA (2022) Identifying congeners and transformation products of organic contaminants within complex chemical mixtures in impacted surface waters with a top-down non-targeted screening workflow. Sci Total Environ. 822, 153540","journal-title":"Sci Total Environ"},{"key":"4227_CR8","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.scitotenv.2015.06.067","volume":"532","author":"R Gurke","year":"2015","unstructured":"Gurke R, R\u00f6\u00dfler M, Marx C, Diamond S et al (2015) Occurrence and removal of frequently prescribed pharmaceuticals and corresponding metabolites in wastewater of a sewage treatment plant. Sci Total Environ 532:762\u2013770","journal-title":"Sci Total Environ"},{"key":"4227_CR10","doi-asserted-by":"publisher","first-page":"102298","DOI":"10.1016\/j.jglr.2024.102298","volume":"50","author":"C Johannessen","year":"2024","unstructured":"Johannessen C, Helm PA, Parnis JM, Kleywegt S, Metcalfe CD (2024) Targeted screening of passive samplers as an early warning of novel contaminants in the Great Lakes Basin. J Great Lakes Res 50:102298","journal-title":"J Great Lakes Res"},{"key":"4227_CR11","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1002\/etc.3124","volume":"35","author":"S Kleywegt","year":"2016","unstructured":"Kleywegt S, Pileggi V, Lam YM, Elises A et al (2016) The contribution of pharmaceutically active compounds from healthcare facilities to a receiving sewage treatment plant in Canada. Environ Toxicol Chem 35:850\u2013862","journal-title":"Environ Toxicol Chem"},{"key":"4227_CR14","doi-asserted-by":"publisher","first-page":"8716","DOI":"10.1021\/es202404c","volume":"45","author":"DB Mawhinney","year":"2011","unstructured":"Mawhinney DB, Young RB, Vanderford BJ, Borch T, Snyder SA (2011) Artificial sweetener sucralose in U.S. drinking water systems. Environ Sci Technol 45:8716\u20138722","journal-title":"Environ Sci Technol"},{"key":"4227_CR12","doi-asserted-by":"crossref","unstructured":"Meng D, Fan D-L, Gu W, Wang Z et al (2020) Development of an integral strategy for non-target and target analysis of site-specific potential contaminants in surface water: a case 427 study of Dianshan Lake, China. Chemosphere. 243; 125367","DOI":"10.1016\/j.chemosphere.2019.125367"},{"key":"4227_CR13","doi-asserted-by":"publisher","first-page":"3533","DOI":"10.1021\/es030653q","volume":"38","author":"X-S Miao","year":"2004","unstructured":"Miao X-S, Bishay F, Chen M, Metcalfe CD (2004) Occurrence of antimicrobials in the final effluents of wastewater treatment plants in Canada. Environ Sci Technol 38:3533\u20133541","journal-title":"Environ Sci Technol"},{"key":"4227_CR15","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1016\/j.scitotenv.2012.10.046","volume":"442","author":"M Oosterhuis","year":"2013","unstructured":"Oosterhuis M, Sacher F, ter Laak TI (2013) Prediction of concentration levels of metformin and other high consumption pharmaceuticals in wastewater and regional surface water based on sales data. Sci Total Environ 442:380\u2013388","journal-title":"Sci Total Environ"},{"key":"4227_CR16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.watres.2014.08.053","volume":"72","author":"B Petrie","year":"2015","unstructured":"Petrie B, Barden R, Kasprzyk-Hordern B (2015) A review on emerging contaminants in wastewaters and the environment: Current knowledge, understudied areas and recommendations for future monitoring. Water Res 72:3\u201327","journal-title":"Water Res"},{"key":"4227_CR9","doi-asserted-by":"publisher","first-page":"125490","DOI":"10.1016\/j.jhazmat.2021.125490","volume":"414","author":"Y Qian","year":"2021","unstructured":"Qian Y, Wang X, Wu G, Wang L et al (2021) Screening priority indicator pollutants in full-scale wastewater treatment plants by non-target analysis. J Hazard Mater 414:125490","journal-title":"J Hazard Mater"},{"key":"4227_CR17","doi-asserted-by":"publisher","first-page":"102297","DOI":"10.1016\/j.jglr.2024.102297","volume":"50","author":"T Sultana","year":"2024","unstructured":"Sultana T, Eysseric E, Segura PA, Helm PA, Kleywegt S, Metcalfe CD (2024) Passive sampling with targeted and non-targeted analysis as an early warning of water-soluble contaminants of emerging concern in the Great Lakes. J Great Lakes Res 50:102297","journal-title":"J Great Lakes Res"},{"key":"4227_CR18","unstructured":"US EPA Fifth Contaminant Candidate List (CCL 5), 2022. US EPA, Washington, DC, USA. Available on-line at: https:\/\/www.epa.gov\/ccl\/contaminant-candidate-list-5-ccl-5"},{"key":"4227_CR19","unstructured":"US EPA, Fifth, US EPA Unregulated Contaminant Monitoring Rule, Washington DC (2021) USA. Available on-line at: https:\/\/www.epa.gov\/dwucmr\/fifth-unregulated-contaminant-monitoring-rule"},{"key":"4227_CR20","unstructured":"Water Research Foundation A Comprehensive Overview of EDCs and PPCPs in Water. Web Report #4387b, 2015. Available on-line at: https:\/\/www.waterrf.org\/resource\/comprehensive-overview-edcs-and-ppcps-water-0"},{"key":"4227_CR21","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.scitotenv.2017.04.102","volume":"596\u2013597","author":"Y Yang","year":"2017","unstructured":"Yang Y, Sik Ok Y, Kim K-H, Kwon EE, Tsang YF (2017) Occurrences and removal of pharmaceuticals and personal care products (PPCPs) in drinking water and water\/sewage treatment plants: A review. Sci Total Environ 596\u2013597:303\u2013320","journal-title":"Sci Total Environ"}],"container-title":["Bulletin of Environmental Contamination and Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00128-026-04227-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00128-026-04227-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00128-026-04227-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T07:21:24Z","timestamp":1778052084000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00128-026-04227-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,28]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["4227"],"URL":"https:\/\/doi.org\/10.1007\/s00128-026-04227-w","relation":{},"ISSN":["0007-4861","1432-0800"],"issn-type":[{"value":"0007-4861","type":"print"},{"value":"1432-0800","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,28]]},"assertion":[{"value":"31 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts or competing interests to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"<!--Emphasis Type='Bold' removed--> Conflicts of interests"}}],"article-number":"75"}}