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Um die unterschiedliche Verteilung von Fx entlang der Wirbels\u00e4ule (WS) besser zu verstehen, wurden morphologische und osteodensitometrische Untersuchungen mittels Computertomographie (CT) in den verschiedenen WS-Abschnitten durchgef\u00fchrt. Zudem war zu kl\u00e4ren, ob die bei CT-Untersuchungen aus anderen Indikationen gefunden Hounsfield-Einheiten (HE) mit der Knochendichte korrelieren und Anlass f\u00fcr eine osteologische Diagnostik sein k\u00f6nnten.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Material und Methoden<\/jats:title>\n                <jats:p>Von 26\u00a0K\u00f6rperspenden wurden die gesamten WS in einem Plexiglas-Wasser-Phantom fixiert und mittels hochaufl\u00f6sende Spiral-CT analysiert. Zus\u00e4tzlich erfolgte die Messung der CT-morphologischen Spongiosadichte in HE von C3 bis S2 (624 Wirbelk\u00f6rper). Der Knochenmineralgehalt (KMG, mg\/ml) wurde ermittelt und zur Absch\u00e4tzung einer Osteoporose (OPO) herangezogen.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Ergebnisse<\/jats:title>\n                <jats:p>Bei allen WS lag eine OPO vor. Bei einem KMG unterhalb von 60\u202fmg\/ml fanden sich signifikant vermehrte Sinterungsfrakturen im thorakalen und thorakolumbalen Bereich. Osteoporotische Insuffizienzfrakturen im HWS-Bereich fanden sich insgesamt nicht. Die Spongiosadichte war signifikant h\u00f6her in den zervikalen (Median 188,6 HE) als in den lumbalen (Median 63,6 HE) und sakralen (Median 25,5 HE) Wirbelk\u00f6rpern aller untersuchten WS.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Schlussfolgerung<\/jats:title>\n                <jats:p>Ein KMG-Verlust der Wirbelk\u00f6rperspongiosa f\u00fchrt zu einem erh\u00f6hten Fx-Risiko, welches sich auch bei den verwendeten WS findet. Jedoch wird im zervikalen Bereich ein scheinbarer Schwellenwert f\u00fcr das Auftreten von Sinterungsfrakturen nicht unterschritten. Einen Schwellenwert f\u00fcr HE zu finden, w\u00e4re f\u00fcr die klinische Praxis relevant.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00132-022-04261-6","type":"journal-article","created":{"date-parts":[[2022,5,23]],"date-time":"2022-05-23T11:04:16Z","timestamp":1653303856000},"page":"547-555","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Insuffizienzfrakturen der Wirbels\u00e4ule in Abh\u00e4ngigkeit von der spongi\u00f6sen Knochendichte","Insufficiency fractures of the spine in relation to cancellous bone density"],"prefix":"10.1007","volume":"51","author":[{"given":"Guido","family":"Schr\u00f6der","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Flachsmeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus Maximilian","family":"Kullen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian Ramin","family":"Andresen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marko","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Hiepe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Christof","family":"Schober","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reimer","family":"Andresen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,23]]},"reference":[{"issue":"10","key":"4261_CR1","doi-asserted-by":"publisher","first-page":"1738","DOI":"10.1016\/j.spinee.2021.03.008","volume":"21","author":"DP Ahern","year":"2021","unstructured":"Ahern\u00a0DP, McDonnell\u00a0JM, Riffault\u00a0M, Evans\u00a0S, Wagner\u00a0SC, Vaccaro\u00a0AR, Hoey\u00a0DA, Butler\u00a0JS (2021) A meta-analysis of the diagnostic accuracy of Hounsfield units on computed topography relative to dual-energy X\u2011ray absorptiometry for the diagnosis of osteoporosis in the spine surgery population. 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