{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:13:26Z","timestamp":1793708006722,"version":"4.6.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Orthop\u00e4die"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s00132-026-04838-5","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T05:05:00Z","timestamp":1779080700000},"page":"545-550","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Extrakorporale Sto\u00dfwellentherapie (ESWT) in der Handchirurgie","Extracorporeal shockwave therapy (ESWT) in hand surgery"],"prefix":"10.1007","volume":"55","author":[{"given":"Karsten","family":"Knobloch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"issue":"10","key":"4838_CR1","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1302\/2058-5241.5.190067","volume":"5","author":"V Auersperg","year":"2020","unstructured":"Auersperg\u00a0V, Trieb\u00a0K (2020) Extracorporeal shockwave therapy: an update. EFORT Open Rev 5(10):584\u2013592. https:\/\/doi.org\/10.1302\/2058-5241.5.190067","journal-title":"EFORT Open Rev"},{"key":"4838_CR2","doi-asserted-by":"publisher","DOI":"10.1038\/nature13251","author":"SH Woo","year":"2014","unstructured":"Woo\u00a0SH, Ranade\u00a0S, Weyer\u00a0AD et\u00a0al (2014) Piezo2 is required for Merkel-cell mechanotransduction. Nature. https:\/\/doi.org\/10.1038\/nature13251","journal-title":"Nature"},{"key":"4838_CR3","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1038\/s41586-020-2933-1","volume":"587","author":"JM Kefauver","year":"2020","unstructured":"Kefauver\u00a0JM, Ward\u00a0AB, Patapoutian\u00a0A (2020) Discoveries in structure and physiology of mechanically activated ion channels. Nature 587:567\u2013576. https:\/\/doi.org\/10.1038\/s41586-020-2933-1","journal-title":"Nature"},{"issue":"4","key":"4838_CR4","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1097\/JS9.0000000000002261","volume":"111","author":"O Wess","year":"2025","unstructured":"Wess\u00a0O, Mayer\u00a0J (2025) The interaction of shock waves with biological tissue - momentum transfer, the key for tissue stimulation and fragmentation. Int J Surg 111(4):2810\u20132818","journal-title":"Int J Surg"},{"key":"4838_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2024.117196","author":"B Wang","year":"2024","unstructured":"Wang\u00a0B, Shao\u00a0W, Zhao\u00a0Y et\u00a0al (2024) Radial extracorporeal shockwave promotes osteogenesis-angiogenesis coupling of bone marrow stromal cells from senile osteoporosis via activating the Piezo1\/CaMKII\/CREB axis. Bone. https:\/\/doi.org\/10.1016\/j.bone.2024.117196","journal-title":"Bone"},{"key":"4838_CR6","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-013-9712-1","author":"J Holfeld","year":"2014","unstructured":"Holfeld\u00a0J, Tepek\u00f6yl\u00fc\u00a0C, Kozaryn\u00a0R et\u00a0al (2014) Shockwave therapy differentially stimulates endothelial cells: implications on the control of inflammation via toll-like receptor 3. Inflammmation. https:\/\/doi.org\/10.1007\/s10753-013-9712-1","journal-title":"Inflammmation"},{"key":"4838_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207574","author":"D Heimes","year":"2020","unstructured":"Heimes\u00a0D, Wiesmann\u00a0N, Eckrich\u00a0J et\u00a0al (2020) In vivo modulation of angiogenesis and immune response on a collagen matrix via extracorporeal shockwaves. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms21207574","journal-title":"Int J Mol Sci"},{"key":"4838_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22157844","author":"JS Holsapple","year":"2021","unstructured":"Holsapple\u00a0JS, Cooper\u00a0B, Berry\u00a0SH et\u00a0al (2021) Low intensity shockwave treatment modulates macrophage functions beneficial to healing chronic wounds. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms22157844","journal-title":"Int J Mol Sci"},{"issue":"6","key":"4838_CR9","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1093\/cvr\/cvz209","volume":"116","author":"C Gollmann-Tepek\u00f6yl\u00fc","year":"2020","unstructured":"Gollmann-Tepek\u00f6yl\u00fc\u00a0C, P\u00f6lzl\u00a0L, Graber\u00a0M et\u00a0al (2020) miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy. Cardiovasc Res 116(6):1226\u20131236. https:\/\/doi.org\/10.1093\/cvr\/cvz209","journal-title":"Cardiovasc Res"},{"key":"4838_CR10","doi-asserted-by":"publisher","DOI":"10.3791\/61508","author":"L P\u00f6lzl","year":"2020","unstructured":"P\u00f6lzl\u00a0L, N\u00e4gele\u00a0F, Hirsch\u00a0J et\u00a0al (2020) Exosome isolation after in vitro shock wave therapy. J\u00a0Vis Exp. https:\/\/doi.org\/10.3791\/61508","journal-title":"J Vis Exp"},{"key":"4838_CR11","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-00104-4","author":"L Wu","year":"2025","unstructured":"Wu\u00a0L, Li\u00a0Z, Song\u00a0W et\u00a0al (2025) Cardiac shock wave therapy-induced exosome derived from OGD\/R-treated H9c2 cells carrying miR-98-5p promote HUVEC angiogenesis. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-025-00104-4","journal-title":"Sci Rep"},{"key":"4838_CR12","doi-asserted-by":"publisher","DOI":"10.1093\/ehjopen\/oeaf011","author":"M Graber","year":"2025","unstructured":"Graber\u00a0M, Gollmann-Tepek\u00f6yl\u00fc\u00a0C, Schweiger\u00a0V et\u00a0al (2025) Modulation of cell fate by shock wave therapy in ischaemic heart disease. Eur Heart J Open. https:\/\/doi.org\/10.1093\/ehjopen\/oeaf011","journal-title":"Eur Heart J Open"},{"issue":"10","key":"4838_CR13","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1007\/s00104-008-1561-3","volume":"79","author":"K Knobloch","year":"2008","unstructured":"Knobloch\u00a0K, Gohritz\u00a0A, Reuss\u00a0E, Vogt\u00a0PM (2008) Nicotine in plastic surgery: a review. Chirurg 79(10):956\u2013962","journal-title":"Chirurg"},{"key":"4838_CR14","unstructured":"Corrado B, Russo S, Gigliotti S, De Durante C, Canero R (2000) Shockwave treatment for nonunions of carpal scaphoid. In: Coombs, Schaden, Zhou (Eds), Musculoskeletal shockwave therapy."},{"issue":"5","key":"4838_CR15","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1055\/a-1250-8078","volume":"52","author":"M M\u00fchldorfer-Fodor","year":"2020","unstructured":"M\u00fchldorfer-Fodor\u00a0M, Wagner\u00a0M, Kottmann\u00a0T, von Schonhoven\u00a0J, Prommersberger\u00a0KJ (2020) Comparison of scaphoid reconstruction with a non-vascularised bone graft, with and without shock waves, preliminary results. Handchir Mikrochir Plast Chir 52(5):404\u2013412","journal-title":"Handchir Mikrochir Plast Chir"},{"issue":"9","key":"4838_CR16","doi-asserted-by":"publisher","first-page":"1452","DOI":"10.1016\/j.ultrasmedbio.2011.06.003","volume":"37","author":"C D\u2019Agostino","year":"2011","unstructured":"D\u2019Agostino\u00a0C, Romeo\u00a0P, Amelio\u00a0E, Sansone\u00a0V (2011) Effectiveness of ESWT in the treatment of Kienb\u00f6ck\u2019s disease. Ultrasound Med Biol 37(9):1452\u20131456","journal-title":"Ultrasound Med Biol"},{"issue":"1","key":"4838_CR17","doi-asserted-by":"publisher","first-page":"92","DOI":"10.5535\/arm.2018.42.1.92","volume":"42","author":"F Ioppolo","year":"2018","unstructured":"Ioppolo\u00a0F, Saracino\u00a0F, Rizzo\u00a0RS, Monacelli\u00a0G, Lanni\u00a0D, Di Sante\u00a0L, Cacchio\u00a0A, Santilli\u00a0V, Venditto\u00a0T (2018) Comparison between extracorporeal shock wave therapy and intra-articular hyaluronic acid injections in the treatment of first carpometacarpal joint osteoarthritis. Ann Rehabil Med 42(1):92\u2013100","journal-title":"Ann Rehabil Med"},{"key":"4838_CR18","doi-asserted-by":"publisher","first-page":"143","DOI":"10.2147\/OAJSM.S108126","volume":"7","author":"N Malliaropoulos","year":"2016","unstructured":"Malliaropoulos\u00a0N, Jury\u00a0R, Pyne\u00a0D, Padhiar\u00a0N, Turner\u00a0J, Korakakis\u00a0V, Meke\u00a0M, Lohrer\u00a0H (2016) Radial extracorporeal shock wave therapy for the treatment of finger tenosynovitis (trigger digit). Open Access J Sports Med 7:143\u2013151","journal-title":"Open Access J Sports Med"},{"issue":"9","key":"4838_CR19","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1177\/1753193415622733","volume":"41","author":"P Yildirim","year":"2016","unstructured":"Yildirim\u00a0P, Gultekin\u00a0A, Yildirim\u00a0A, Karahan\u00a0AY, Tok\u00a0F (2016) Extracorporeal shock wave therapy versus corticosteroid injection in the treatment of trigger finger: a randomized controlled study. J\u00a0Hand Surg Eur Vol 41(9):977\u2013983","journal-title":"J Hand Surg Eur Vol"},{"key":"4838_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2024.115052","volume":"384","author":"B Cao","year":"2025","unstructured":"Cao\u00a0B, Tang\u00a0X, Liu\u00a0C et\u00a0al (2025) Unlocking new frontiers: the cellular and molecular impact of extracorporeal shock wave therapy (ESWT) on central nervous systems (CNS) disorders and peripheral nerve injuries (PNI). Exp Neurol 384:115052","journal-title":"Exp Neurol"},{"issue":"23","key":"4838_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12237363","volume":"12","author":"L Zhang","year":"2023","unstructured":"Zhang\u00a0L, Yang\u00a0T, Pang\u00a0L et\u00a0al (2023) Effects of extracorporeal shock wave therapy in patients with mild-to-moderate carpal tunnel syndrome: an updated systematic review with meta-analysis. J\u00a0Clin Med 12(23):7363","journal-title":"J Clin Med"},{"issue":"3","key":"4838_CR22","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3344\/kjp.2021.34.3.315","volume":"34","author":"MC Turgut","year":"2021","unstructured":"Turgut\u00a0MC, Saglam\u00a0G, Toy\u00a0S (2021) Efficacy of extracorporeal shock wave therapy for pillar pain after open carpal tunnel release: a double-blind, randomized, sham-controlled study. Korean J Pain 34(3):315\u2013321","journal-title":"Korean J Pain"},{"issue":"4","key":"4838_CR23","doi-asserted-by":"publisher","first-page":"388","DOI":"10.5606\/tftrd.2020.3956","volume":"66","author":"RK Ulucak\u00f6y","year":"2020","unstructured":"Ulucak\u00f6y\u00a0RK, Yurdakul\u00a0FG, Bodur\u00a0H (2020) Extracorporeal shock wave therapy as a conservative treatment option for carpal tunnel syndrome: a double-blind, prospective, randomized, placebo-controlled trial. Turk J Phys Med Rehabil 66(4):388\u2013397","journal-title":"Turk J Phys Med Rehabil"},{"issue":"4","key":"4838_CR24","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.jht.2023.12.009","volume":"37","author":"A Ghasemia","year":"2024","unstructured":"Ghasemia\u00a0A, Olyaei\u00a0GR, Bagheri\u00a0H et\u00a0al (2024) A randomized clinical trial on the changing of median nerve cross-sectional area and pain after extracorporeal shockwave and low level laser therapy added to conventional physical therapy in patients with mild-to-moderate carpal tunnel syndrome. J\u00a0Hand Ther 37(4):555\u2013562","journal-title":"J Hand Ther"},{"issue":"1","key":"4838_CR25","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1007\/s10103-021-03254-9","volume":"37","author":"K Knobloch","year":"2022","unstructured":"Knobloch\u00a0K, Hellweg\u00a0M, Sorg\u00a0H, Nedelka\u00a0T (2022) Focused electromagnetic high-energetic extracorporeal shockwave (ESWT) reduces pain levels in the nodular stage of Dupuytren\u2019s disease - a randomized controlled trial (DupuyShock). Lasers Med Sci 37(1):323\u2013333","journal-title":"Lasers Med Sci"},{"issue":"10","key":"4838_CR26","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1016\/j.apmr.2024.05.030","volume":"105","author":"A Yazdani","year":"2024","unstructured":"Yazdani\u00a0A, Nasri\u00a0P, Mahdavi\u00a0SB (2024) The effects of shock wave therapy on the symptoms and function in individuals with Dupuytren disease: a systematic review. Arch Phys Med Rehabil 105(10):1985\u20131992","journal-title":"Arch Phys Med Rehabil"}],"updated-by":[{"DOI":"10.1007\/s00132-026-04861-6","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T00:00:00Z","timestamp":1784160000000}}],"container-title":["Die Orthop\u00e4die"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00132-026-04838-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00132-026-04838-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00132-026-04838-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:08:42Z","timestamp":1784189322000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00132-026-04838-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":26,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["4838"],"URL":"https:\/\/doi.org\/10.1007\/s00132-026-04838-5","relation":{},"ISSN":["2731-7145","2731-7153"],"issn-type":[{"value":"2731-7145","type":"print"},{"value":"2731-7153","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,18]]},"assertion":[{"value":"5 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 June 2026","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"In diesem Artikel wurde die Krankheit Morbus Kienb\u00f6ck falsch geschrieben. Dies betrifft die folgenden Textstellen:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"\u2013 Knochenheilungsst\u00f6rungen der HandLunatummalazie\/Morbus Kienboek \u00b7Rhizarthrose","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Auch Mondbeinnekrosen wie der Morbus Kienboek k\u00f6nnen durch eine fokussiertehochenergetische ESWT sowohl symptomatisch schmerz\u00e4rmer werden als auchin der MRT Verbesserungen des Signalmusters aufzeigen.","order":9,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Lunatummalazie\/Morbus Kienboek","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Bei der Lunatummalazie, dem MorbusKienboek als Osteonekrose des Mond-beins in der proximalen Handwurzelreiheliegen Erfahrungen aus Italien vor.","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"In lunate necrosis aka Morbus Kienboek focused high-energetic ESWT can reduce pain and improve MRI.","order":12,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Korrekt sollte es lauten Morbus Kienb\u00f6ck:","order":13,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"\u2013 Knochenheilungsst\u00f6rungen der HandLunatummalazie\/Morbus Kienb\u00f6ck \u00b7Rhizarthrose","order":14,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Auch Mondbeinnekrosen wie der Morbus Kienb\u00f6ck k\u00f6nnen durch eine fokussiertehochenergetische ESWT sowohl symptomatisch schmerz\u00e4rmer werden als auchin der MRT Verbesserungen des Signalmusters aufzeigen.","order":15,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Lunatummalazie\/Morbus Kienb\u00f6ck","order":16,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Bei der Lunatummalazie, dem Morbus Kienb\u00f6ck als Osteonekrose des Mond-beins in der proximalen Handwurzelreiheliegen Erfahrungen aus Italien vor.","order":17,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"In lunate necrosis aka Morbus Kienb\u00f6ck focused high-energetic ESWT can reduce pain and improve MRI.","order":18,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Der Originalbeitrag wurde korrigiert.","order":19,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 July 2026","order":20,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Erratum","order":21,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Zu diesem Beitrag wurde ein Erratum ver\u00f6ffentlicht:","order":22,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00132-026-04861-6","URL":"https:\/\/doi.org\/10.1007\/s00132-026-04861-6","order":23,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"K.\u00a0Knobloch erhielt Vortragshonorare von Storz Medical.","order":1,"name":"Ethics","label":"Interessenkonflikt","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}},{"value":"F\u00fcr diesen Beitrag wurden von den Autor\/-innen keine Studien an Menschen oder Tieren durchgef\u00fchrt. F\u00fcr die aufgef\u00fchrten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Einhaltung ethischer Richtlinien"}}]}}