{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:48:36Z","timestamp":1776926916604,"version":"3.51.2"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2004,5,18]],"date-time":"2004-05-18T00:00:00Z","timestamp":1084838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2004,5,18]],"date-time":"2004-05-18T00:00:00Z","timestamp":1084838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1007\/s00134-004-2316-3","type":"journal-article","created":{"date-parts":[[2004,5,17]],"date-time":"2004-05-17T09:15:46Z","timestamp":1084785346000},"page":"1384-1389","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Practices in non-neutropenic ICU patients with Candida-positive airway specimens"],"prefix":"10.1007","volume":"30","author":[{"given":"Elie","family":"Azoulay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Ralph","family":"Zahar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mait\u00e9","family":"Garrouste-Orgeas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Adrie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Moine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"de Lassence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"Timsit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2004,5,18]]},"reference":[{"key":"2316_CR1","first-page":"13","volume":"77","author":"Bodey","year":"1984","unstructured":"Bodey GP (1984) Candidiasis in cancer patients. Am J Med 77:13\u201319","journal-title":"Am J Med"},{"key":"2316_CR2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1086\/323335","volume":"34","author":"Ascioglu","year":"2002","unstructured":"Ascioglu S, Rex JH, de Pauw B, Bennett JE, Bille J, Crokaert F, Denning DW, Donnelly JP, Edwards JE, Erjavec Z, Fiere D, Lortholary O, Maertens J, Meis JF, Patterson TF, Ritter J, Selleslag D, Shah PM, Stevens DA, Walsh TJ (2002) Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 34:7\u201314","journal-title":"Clin Infect Dis"},{"key":"2316_CR3","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1001\/archinte.1989.00390100145030","volume":"149","author":"Wey","year":"1989","unstructured":"Wey SB, Mori M, Pfaller MA, Woolson RF, Wenzel RP (1989) Risk factors for hospital-acquired candidemia. A matched case-control study. Arch Intern Med 149:2349\u20132353","journal-title":"Arch Intern Med"},{"key":"2316_CR4","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s001340050334","volume":"23","author":"Petri","year":"1997","unstructured":"Petri MG, Konig J, Moecke HP, Gramm HJ, Barkow H, Kujath P, Dennhart R, Schafer H, Meyer N, Kalmar P, Thulig P, Muller J, Lode H (1997) Epidemiology of invasive mycosis in ICU patients: a prospective multicenter study in 435 non-neutropenic patients. Paul-Ehrlich Society for Chemotherapy, Divisions of Mycology and Pneumonia Research. Intensive Care Med 23:317\u2013325","journal-title":"Intensive Care Med"},{"key":"2316_CR5","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0002-9610(05)80666-X","volume":"166","author":"Eubanks","year":"1993","unstructured":"Eubanks PJ, de Virgilio C, Klein S, Bongard F (1993) Candida sepsis in surgical patients. Am J Surg 166:617\u2013619; discussion 619\u201320","journal-title":"Am J Surg"},{"key":"2316_CR6","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00000658-199412000-00008","volume":"220","author":"Pittet","year":"1994","unstructured":"Pittet D, Monod M, Suter PM, Frenk E, Auckenthaler R (1994) Candida colonization and subsequent infections in critically ill surgical patients. Ann Surg 220:751\u2013758","journal-title":"Ann Surg"},{"key":"2316_CR7","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/S0750-7658(01)00374-4","volume":"20","author":"Eggimann","year":"2001","unstructured":"Eggimann P, Pittet D (2001) Candidiasis among non-neutropenic patients: from colonization to infection. Ann Fr Anesth Reanim 20:382\u2013388","journal-title":"Ann Fr Anesth Reanim"},{"key":"2316_CR8","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/0002-9343(77)90546-0","volume":"63","author":"Masur","year":"1977","unstructured":"Masur H, Rosen PP, Armstrong D (1977) Pulmonary disease caused by Candida species. Am J Med 63:914\u2013925","journal-title":"Am J Med"},{"key":"2316_CR9","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1001\/jama.1995.03530080055041","volume":"274","author":"Vincent","year":"1995","unstructured":"Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH, Wolff M, Spencer RC, Hemmer M (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 274:639\u2013644","journal-title":"JAMA"},{"key":"2316_CR10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1097\/00003246-200202000-00009","volume":"30","author":"Stephan","year":"2002","unstructured":"Stephan F, Yang K, Tankovic J, Soussy CJ, Dhonneur G, Duvaldestin P, Brochard L, Brun-Buisson C, Harf A, Delclaux C (2002) Impairment of polymorphonuclear neutrophil functions precedes nosocomial infections in critically ill patients. Crit Care Med 30:315\u2013322","journal-title":"Crit Care Med"},{"key":"2316_CR11","doi-asserted-by":"publisher","first-page":"S124","DOI":"10.1007\/s001340051129","volume":"26","author":"Kox","year":"2000","unstructured":"Kox WJ, Volk T, Kox SN, Volk HD (2000) Immunomodulatory therapies in sepsis. Intensive Care Med 26:S124\u2013128","journal-title":"Intensive Care Med"},{"key":"2316_CR12","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1093\/clinids\/20.6.1526","volume":"20","author":"Jarvis","year":"1995","unstructured":"Jarvis WR (1995) Epidemiology of nosocomial fungal infections, with emphasis on Candida species. Clin Infect Dis 20:1526\u20131530","journal-title":"Clin Infect Dis"},{"key":"2316_CR13","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1097\/00003246-199906000-00019","volume":"27","author":"Eggimann","year":"1999","unstructured":"Eggimann P, Francioli P, Bille J, Schneider R, Wu MM, Chapuis G, Chiolero R, Pannatier A, Schilling J, Geroulanos S, Glauser MP, Calandra T (1999) Fluconazole prophylaxis prevents intra-abdominal candidiasis in high-risk surgical patients. Crit Care Med 27:1066\u20131072","journal-title":"Crit Care Med"},{"key":"2316_CR14","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s001340050552","volume":"24","author":"Vincent","year":"1998","unstructured":"Vincent JL, Anaissie E, Bruining H, Demajo W, el-Ebiary M, Haber J, Hiramatsu Y, Nitenberg G, Nystrom PO, Pittet D, Rogers T, Sandven P, Sganga G, Schaller MD, Solomkin J (1998) Epidemiology, diagnosis and treatment of systemic Candida infection in surgical patients under intensive care. Intensive Care Med 24:206\u2013216","journal-title":"Intensive Care Med"},{"key":"2316_CR15","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1001\/archinte.155.15.1649","volume":"155","author":"Fernandez-Sola","year":"1995","unstructured":"Fernandez-Sola J, Junque A, Estruch R, Monforte R, Torres A, Urbano-Marquez A (1995) High alcohol intake as a risk and prognostic factor for community-acquired pneumonia. Arch Intern Med 155:1649\u20131654","journal-title":"Arch Intern Med"},{"key":"2316_CR16","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2337\/diacare.3.1.187","volume":"3","author":"Wheat","year":"1980","unstructured":"Wheat LJ (1980) Infection and diabetes mellitus. Diabetes Care 3:187\u2013197","journal-title":"Diabetes Care"},{"key":"2316_CR17","doi-asserted-by":"crossref","unstructured":"Haron E, Vartivarian S, Anaissie E, Dekmezian R, Bodey GP (1993) Primary Candida pneumonia. Experience at a large cancer center and review of the literature. Medicine (Baltimore) 72:137\u2013142","DOI":"10.1097\/00005792-199372030-00001"},{"key":"2316_CR18","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1001\/archinte.138.6.964","volume":"138","author":"Rose","year":"1978","unstructured":"Rose HD, Sheth NK (1978) Pulmonary candidiasis. A clinical and pathological correlation. Arch Intern Med 138:964\u2013965","journal-title":"Arch Intern Med"},{"key":"2316_CR19","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S1164-6756(01)00120-7","volume":"10","author":"E Azoulay","year":"2001","unstructured":"Azoulay E, Limal N, Mayaud C, Schlemmer B (2001) Bronchial specimens positive to Candida: infection or colonization. R\u00e9animation Urgences 10:323\u2013328","journal-title":"R\u00e9animation Urgences"},{"key":"2316_CR20","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1164\/ajrccm.156.2.9612023","volume":"156","author":"el-Ebiary","year":"1997","unstructured":"el-Ebiary M, Torres A, Fabregas N, de la Bellacasa JP, Gonzalez J, Ramirez J, del Bano D, Hernandez C, Jimenez de Anta MT (1997) Significance of the isolation of Candida species from respiratory samples in critically ill, non-neutropenic patients. An immediate postmortem histologic study. Am J Respir Crit Care Med 156:583\u2013590","journal-title":"Am J Respir Crit Care Med"},{"key":"2316_CR21","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1378\/chest.114.1.146","volume":"114","author":"Rello","year":"1998","unstructured":"Rello J, Esandi ME, Diaz E, Mariscal D, Gallego M, Valles J (1998) The role of Candida sp isolated from bronchoscopic samples in non-neutropenic patients. Chest 114:146\u2013149","journal-title":"Chest"},{"key":"2316_CR22","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1086\/313749","volume":"30","author":"Rex","year":"2000","unstructured":"Rex JH, Walsh TJ, Sobel JD, Filler SG, Pappas PG, Dismukes WE, Edwards JE (2000) Practice guidelines for the treatment of candidiasis. Infectious Diseases Society of America. Clin Infect Dis 30:662\u2013678","journal-title":"Clin Infect Dis"},{"key":"2316_CR23","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1097\/00003246-199911000-00023","volume":"27","author":"Ahmed","year":"1999","unstructured":"Ahmed NA, McGill S, Yee J, Hu F, Michel RP, Christou NV (1999) Mechanisms for the diminished neutrophil exudation to secondary inflammatory sites in infected patients with a systemic inflammatory response (sepsis). Crit Care Med 27:2459\u20132468","journal-title":"Crit Care Med"},{"key":"2316_CR24","doi-asserted-by":"publisher","first-page":"1698","DOI":"10.1007\/s00134-002-1539-4","volume":"28","author":"Calandra","year":"2002","unstructured":"Calandra T, Marchetti O (2002) Antifungal prophylaxis for intensive care unit patients: let\u2019s fine tune it. Intensive Care Med 28(12):1698\u20131700","journal-title":"Intensive Care Med"},{"key":"2316_CR25","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1007\/s00134-002-1540-y","volume":"28","author":"Garbino","year":"2002","unstructured":"Garbino J, Lew D, Romand JA, Hugonnet S, Auckenthaler R, Pittet D (2002) Prevention of severe Candida infections in non-neutropenic, high-risk, critically ill patients. A randomized, double-blind, placebo-controlled trial in SDD-treated patients. Intensive Care Med 28(12):1708-1717","journal-title":"Intensive Care Med"},{"key":"2316_CR26","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1086\/342300","volume":"35","author":"Trick","year":"2002","unstructured":"Trick WE, Fridkin SK, Edwards JR, Hajjeh RA, Gaynes RP (2002) Secular trend of hospital-acquired candidemia among intensive care unit patients in the United States during 1989\u20131999. Clin Infect Dis 35:627\u2013630","journal-title":"Clin Infect Dis"},{"key":"2316_CR27","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1086\/520194","volume":"29","author":"Rangel-Frausto","year":"1999","unstructured":"Rangel-Frausto MS, Wiblin T, Blumberg HM, Saiman L, Patterson J, Rinaldi M, Pfaller M, Edwards JE, Jarvis W, Dawson J, Wenzel RP (1999) National epidemiology of mycoses survey (NEMIS): variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units. Clin Infect Dis 29:253\u2013258","journal-title":"Clin Infect Dis"},{"key":"2316_CR28","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1056\/NEJM199203263261301","volume":"326","author":"Goodman","year":"1992","unstructured":"Goodman JL, Winston DJ, Greenfield RA, Chandrasekar PH, Fox B, Kaizer H, Shadduck RK, Shea TC, Stiff P, Friedman DJ et al (1992) A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation. N Engl J Med 326:845\u2013851","journal-title":"N Engl J Med"},{"key":"2316_CR29","doi-asserted-by":"crossref","first-page":"495","DOI":"10.7326\/0003-4819-118-7-199304010-00003","volume":"118","author":"Winston","year":"1993","unstructured":"Winston DJ, Chandrasekar PH, Lazarus HM, Goodman JL, Silber JL, Horowitz H, Shadduck RK, Rosenfeld CS, Ho WG, Islam MZ et al (1993) Fluconazole prophylaxis of fungal infections in patients with acute leukemia. Results of a randomized placebo-controlled, double-blind, multicenter trial. Ann Intern Med 118:495\u2013503","journal-title":"Ann Intern Med"},{"key":"2316_CR30","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1097\/00000658-200104000-00010","volume":"233","author":"Pelz","year":"2001","unstructured":"Pelz RK, Hendrix CW, Swoboda SM, Diener-West M, Merz WG, Hammond J, Lipsett PA (2001) Double-blind placebo-controlled trial of fluconazole to prevent candidal infections in critically ill surgical patients. Ann Surg 233:542\u2013548","journal-title":"Ann Surg"},{"key":"2316_CR31","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1086\/318517","volume":"32","author":"Rex","year":"2001","unstructured":"Rex JH, Sobel JD (2001) Prophylactic antifungal therapy in the intensive care unit. Clin Infect Dis 32:1191\u20131200","journal-title":"Clin Infect Dis"},{"key":"2316_CR32","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1378\/chest.120.1.177","volume":"120","author":"Chen","year":"2001","unstructured":"Chen KY, Ko SC, Hsueh PR, Luh KT, Yang PC (2001) Pulmonary fungal infection: emphasis on microbiological spectra, patient outcome, and prognostic factors. Chest 120:177\u2013184","journal-title":"Chest"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-004-2316-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-004-2316-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-004-2316-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-004-2316-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:27:48Z","timestamp":1744162068000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-004-2316-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5,18]]},"references-count":32,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["2316"],"URL":"https:\/\/doi.org\/10.1007\/s00134-004-2316-3","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5,18]]},"assertion":[{"value":"16 March 2003","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 March 2004","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2004","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}