{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T08:09:40Z","timestamp":1789632580784,"version":"build-2803163510"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,1,24]],"date-time":"2006-01-24T00:00:00Z","timestamp":1138060800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1007\/s00134-005-0015-3","type":"journal-article","created":{"date-parts":[[2006,1,25]],"date-time":"2006-01-25T14:23:33Z","timestamp":1138199013000},"page":"325-328","source":"Crossref","is-referenced-by-count":28,"title":["Levels of vancomycin in the cerebral interstitial fluid after severe head injury"],"prefix":"10.1007","volume":"32","author":[{"given":"Anselmo","family":"Caricato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano","family":"Pennisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo","family":"Mancino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Vigna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Sandroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Arcangeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,1,24]]},"reference":[{"key":"15_CR1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1017\/CBO9780511570216.048","volume-title":"Introduction to the blood-brain barrier; methodology, biology and pathology.","author":"JT Povlishock","year":"1998","unstructured":"Povlishock\u00a0JT (1998) The pathophysiology of blood-brain barrier dysfunction due to traumatic brain injury. In: Pardridge WM (ed) Introduction to the blood-brain barrier; methodology, biology and pathology. Cambridge University Press, Cambridge, pp 441\u2013453"},{"key":"15_CR2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1034\/j.1399-6576.2001.045003390.x","volume":"45","author":"R Bouw","year":"2001","unstructured":"Bouw\u00a0R, Ederoth\u00a0P, Lundberg\u00a0J, Ungerstedt\u00a0U, Nordstrom\u00a0CH, Hammarlud-Udenaes\u00a0M (2001) Increased blood\u2013brain barrier permeability of morphine in a\u00a0patient with severe brain lesions as determined by microdialysis. Acta Anaesthesiol Scand 45:390\u2013392","journal-title":"Acta Anaesthesiol Scand"},{"key":"15_CR3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1365-2125.1999.00850.x","volume":"47","author":"EJ Begg","year":"1999","unstructured":"Begg\u00a0EJ, Barclay\u00a0ML, Kirkpatrick\u00a0CJM (1999) The therapeutic monitoring of antimicrobial agents. Br J Clin Pharmacol 47:23\u201330","journal-title":"Br J Clin Pharmacol"},{"key":"15_CR4","volume-title":"British national formulary.","author":"British National Formulary","year":"2005","unstructured":"British National Formulary (2005) British national formulary, vol 49. British Medical Association and Royal Pharmaceutical Society of Great Britain, London","edition":"49"},{"key":"15_CR5","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/1357-4310(96)88720-X","volume":"2","author":"NJ Abbott","year":"1996","unstructured":"Abbott\u00a0NJ, Romero\u00a0A (1996) Transporting therapeutics across the blood-brain barrier. Mol Med Today 2:106\u2013113","journal-title":"Mol Med Today"},{"key":"15_CR6","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1086\/515003","volume":"27","author":"I Lutsar","year":"1998","unstructured":"Lutsar\u00a0I, McCracken\u00a0GH Jr, Friedland\u00a0IR (1998) Antibiotic pharmacodynamics in cerebrospinal fluid. Clin Infect Dis 27:1117\u20131129","journal-title":"Clin Infect Dis"},{"key":"15_CR7","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1128\/AAC.44.5.1356-1358.2000","volume":"44","author":"J Albanese","year":"2000","unstructured":"Albanese\u00a0J, Leone\u00a0M, Bruguerolle\u00a0B, Ayem\u00a0M, Lacarelle\u00a0B, Martin\u00a0C (2000) Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an Intensive Care Unit. Antimicrob Agents Chemother 44:1356\u20131358","journal-title":"Antimicrob Agents Chemother"},{"key":"15_CR8","doi-asserted-by":"crossref","first-page":"343","DOI":"10.7326\/0003-4819-94-3-343","volume":"94","author":"RC Moellering","year":"1981","unstructured":"Moellering\u00a0RC, Krigstad\u00a0DJ, Greenblatt\u00a0DJ (1981) Vancomycin therapy in patients with impaired renal function: a\u00a0nomogram for dosage. Ann Intern Med 94:343\u2013346","journal-title":"Ann Intern Med"},{"key":"15_CR9","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/jac\/6.3.363","volume":"6","author":"LJ Strausbaugh","year":"1981","unstructured":"Strausbaugh\u00a0LJ, Murray\u00a0TW, Sande\u00a0MA (1981) Comparative penetration of 6 antibiotics into the CSF of rabbits with experimental staphylococcal meningitis. J Antimicrob Chemother 6:363\u2013371","journal-title":"J Antimicrob Chemother"},{"key":"15_CR10","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0731-7085(96)01924-3","volume":"15","author":"CE Mackie","year":"1997","unstructured":"Mackie\u00a0CE, English\u00a0HE, Lelievre\u00a0E, Gordon\u00a0BH, Genissel\u00a0P, Robinson BV(1997) Radioimmunoassay for the measurement of S9788 in serum and microdialysis samples. J Pharm Biomed Anal 15:917\u2013928","journal-title":"J Pharm Biomed Anal"},{"key":"15_CR11","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1046\/j.1471-4159.1997.68020616.x","volume":"68","author":"LL Rocha","year":"1997","unstructured":"Rocha\u00a0LL, Evans\u00a0CJ, Maidment\u00a0NT (1997) Amygdala kindling modifies extracellular opioid peptide content in rat hippocampus measured by microdialysis. J Neurochem 68:616\u2013624","journal-title":"J Neurochem"},{"key":"15_CR12","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0169-409X(00)00114-9","volume":"45","author":"MI Davies","year":"2000","unstructured":"Davies\u00a0MI, Cooper\u00a0JD, Desmond\u00a0SS, Lunte\u00a0CE, Lunte\u00a0SM (2000) Analytical considerations for microdialysis sampling. Adv Drug Deliv Rev 45:169\u2013188","journal-title":"Adv Drug Deliv Rev"},{"key":"15_CR13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/bmc.446","volume":"19","author":"N Plock","year":"2005","unstructured":"Plock\u00a0N, Buerger\u00a0C, Kloft\u00a0C (2005) Successful management of discovered pH dependence in vancomycin recovery studies: novel HPLC method for microdialysis and plasma samples. Biomed Chromatogr 19:237\u2013244","journal-title":"Biomed Chromatogr"},{"key":"15_CR14","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1128\/AAC.34.10.1869","volume":"34","author":"WE Peetermans","year":"1990","unstructured":"Peetermans\u00a0WE, Hoogeterp\u00a0JJ, Hazekamp-Van\u00a0Dokkum\u00a0AM (1990) Antistaphylococcal activities of teicoplanin and vancomycin in vitro and in experimental infection. Antimicrob Agents Chemother 34:1869\u20131874","journal-title":"Antimicrob Agents Chemother"},{"key":"15_CR15","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1128\/AAC.36.8.1766","volume":"36","author":"BH Ackerman","year":"1992","unstructured":"Ackerman\u00a0BH, Vannier\u00a0AM, Eudy\u00a0EB (1992) Analysis of vancomycin time-kill studies with Staphylococcus species by using a\u00a0curve stripping program to describe the relationship between concentration and pharmacodynamic response. Antimicrob Agents Chemother 36:1766\u20131769","journal-title":"Antimicrob Agents Chemother"},{"key":"15_CR16","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1128\/AAC.31.8.1210","volume":"31","author":"CW Stratton","year":"1987","unstructured":"Stratton\u00a0CW, Liu\u00a0C, Weeks\u00a0S (1987) Activity of LY146032 compared with that of methicillin, cefazolin, cefamandole, cefuroxime, ciprofloxacin, and vancomycin against staphylococci as determined by kill-kinetic studies. Antimicrob Agents Chemother; 31:1210\u20131215","journal-title":"Antimicrob Agents Chemother;"},{"key":"15_CR17","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1248\/bpb.26.876","volume":"26","author":"T Iwamoto","year":"2003","unstructured":"Iwamoto\u00a0T, Kagawa\u00a0Y, Kojima\u00a0M (2003) Clinical efficacy of therapeutic drug monitoring in patients receiving vancomycin. Biol Pharm Bull 26:876\u2013879","journal-title":"Biol Pharm Bull"},{"key":"15_CR18","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1093\/jac\/dkf212","volume":"50","author":"CM Tobin","year":"2002","unstructured":"Tobin\u00a0CM, Darville\u00a0JM, Thomson\u00a0AH , Sweeney\u00a0G, Wilson JF, MacGowan\u00a0AP, White\u00a0LO (2002) Vancomycin therapeutic drug monitoring: is there a\u00a0consensus view? The results of a\u00a0UK National External Quality Assessment Scheme (UK NEQAS) for Antibiotic Assays questionnaire. J Antimicr Chemotherapy 50:713\u2013718","journal-title":"J Antimicr Chemotherapy"},{"key":"15_CR19","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2165\/00003088-200241100-00001","volume":"41","author":"ECM Lange De","year":"2002","unstructured":"De Lange ECM, Danhof M (2002) Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting. Clin Pharmacokinet 41:691\u2013703","journal-title":"Clin Pharmacokinet"},{"key":"15_CR20","doi-asserted-by":"crossref","first-page":"757","DOI":"10.3171\/jns.2004.101.5.0757","volume":"101","author":"B Eftekhar","year":"2004","unstructured":"Eftekhar\u00a0B, Ghodsi\u00a0M, Nejat\u00a0F, Ketabchi\u00a0E, Esmaeeli\u00a0B (2004) Prophylactic administration of ceftriaxone for the prevention of meningitis after traumatic pneumocephalus: results of a\u00a0clinical trial. J Neurosurg 101:757\u2013761","journal-title":"J Neurosurg"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-005-0015-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00134-005-0015-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-005-0015-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T08:49:40Z","timestamp":1558601380000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00134-005-0015-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,24]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2006,2]]}},"alternative-id":["15"],"URL":"https:\/\/doi.org\/10.1007\/s00134-005-0015-3","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1,24]]}}}