{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:18:03Z","timestamp":1791303483546,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2005,2,12]],"date-time":"2005-02-12T00:00:00Z","timestamp":1108166400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2005,2,12]],"date-time":"2005-02-12T00:00:00Z","timestamp":1108166400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2005,3]]},"DOI":"10.1007\/s00134-005-2571-y","type":"journal-article","created":{"date-parts":[[2005,2,11]],"date-time":"2005-02-11T12:42:01Z","timestamp":1108125721000},"page":"393-400","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":137,"title":["Candida spp. colonization significance in critically ill medical patients: a prospective study"],"prefix":"10.1007","volume":"31","author":[{"given":"Pierre Emmanuel","family":"Charles","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Dalle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Aube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Marc","family":"Doise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Pierre","family":"Quenot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludwig Serge","family":"Aho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Chavanet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Blettery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,2,12]]},"reference":[{"key":"2571_CR1","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/S0002-9343(89)80392-4","volume":"87","author":"Bross","year":"1989","unstructured":"Bross J, Talbot G, Maislin G, Hurwitz S, Strom B (1989) Risk factors for nosocomial candidemia: a case-control study in adults without leukemia. Am J Med 87:614\u2013620","journal-title":"Am J Med"},{"key":"2571_CR2","doi-asserted-by":"publisher","first-page":"2349","DOI":"10.1001\/archinte.149.10.2349","volume":"149","author":"Wey","year":"1989","unstructured":"Wey S, Mori M, Pfaller M, Woolson R, Wenzel R (1989) Risk factors for hospital-acquired candidemia. Arch Intern Med 149:2349\u20132353","journal-title":"Arch Intern Med"},{"key":"2571_CR3","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1097\/00000658-199412000-00008","volume":"220","author":"Pittet","year":"1994","unstructured":"Pittet D, Monod M, Suter P, Frenk E, Auckenthaler R (1994) Candida colonization and subsequent infections in critically ill surgical patients. Ann Surg 220:751\u2013758","journal-title":"Ann Surg"},{"key":"2571_CR4","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/S0140-6736(89)92043-6","volume":"II","author":"Calandra","year":"1989","unstructured":"Calandra T, Bille J, Schneider R, Mosimann F, Francioli P (1989) Clinical significance of Candida isolated from peritoneum in surgical patients. Lancet II:1437\u20131440","journal-title":"Lancet"},{"key":"2571_CR5","first-page":"107","volume":"60","author":"Slotman","year":"1994","unstructured":"Slotman G, Shapiro E, Moffa S (1994) Fungal sepsis: multisite colonization versus fungemia. Am Surg 60:107\u2013113","journal-title":"Am Surg"},{"key":"2571_CR6","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1439-0507.1997.tb00209.x","volume":"40","author":"Tran","year":"1997","unstructured":"Tran L, Auger P, Marchand R, Carrier M, Pelletier C (1997) Epidemiological study of Candida spp. colonization in cardiovascular surgical patients. Mycoses 40:169\u2013173","journal-title":"Mycoses"},{"key":"2571_CR7","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/S0750-7658(01)00375-6","volume":"20","author":"Dubeau","year":"2001","unstructured":"Dubeau B, Triboulet C, Winnock S (2001) Utilisation pratique de l\u2019index de colonisation. Ann Fr Anesth Reanim 20:418\u2013420","journal-title":"Ann Fr Anesth Reanim"},{"key":"2571_CR8","first-page":"339","volume":"Surg","author":"Yazdanparast","year":"2001","unstructured":"Yazdanparast K, Auger P, Marchand R, Carrier M, Cartier R (2001) Predictive value of Candida colonization index in 131 patients undergoing two different cardiovascular surgical procedures. J Cardiovasc Surg (Torino) 42:339\u2013343","journal-title":"J Cardiovasc"},{"key":"2571_CR9","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/S0924-8579(00)00147-3","volume":"15","author":"Munoz","year":"2000","unstructured":"Munoz P, Almudena B, Bouza E (2000) Criteria used when initiating antifungal therapy against Candida spp. in the intensive care unit. Int J Antimicrob Agents 15:83\u201390","journal-title":"Int J Antimicrob Agents"},{"key":"2571_CR10","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1001\/archsurg.1997.01430350047008","volume":"132","author":"Gleason","year":"1997","unstructured":"Gleason T, May A, Carapelli D, Farr B, Sawyer R (1997) Emerging evidence of selection of fluconazole-tolerant fungi in surgical intensive care units. Arch Surg 132:1197\u20131202","journal-title":"Arch Surg"},{"key":"2571_CR11","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1001\/archsurg.1997.01430350034006","volume":"132","author":"Safran","year":"1997","unstructured":"Safran D, Dawson E (1997) The effect of empiric and prophylactic treatment with fluconazole on yeast isolates in a surgical trauma intensive care unit. Arch Surg 132:1184\u20131189","journal-title":"Arch Surg"},{"key":"2571_CR12","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1007\/BF01711909","volume":"20","author":"British","year":"1994","unstructured":"British Society for Antimicrobial Chemotherapy Working Party (1994) Management of deep Candida infection in surgical and intensive care unit patients. Intensive Care Med 20:522\u2013528","journal-title":"Intensive Care Med"},{"key":"2571_CR13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1086\/514504","volume":"25","author":"Edwards","year":"1997","unstructured":"Edwards JJ, Bodey G, Bowden R, Buchner T, de Pauw B, Filler S, Ghannoum M, Glauser M, Herbrecht R, Kauffman C, Kohno S, Martino P, Meunier F, Mori T, Pfaller M, Rex J, Rogers T, Rubin R, Solomkin J, Viscoli C, Walsh T, White M (1997) International Conference for the Development of a Consensus on the Management and Prevention of Severe Candidal Infections. Clin Infect Dis 25:43\u201359","journal-title":"Clin Infect Dis"},{"key":"2571_CR14","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1086\/313749","volume":"30","author":"Rex","year":"2000","unstructured":"Rex J, Walsh T, Sobel J, Filler S, Pappas P, Dismukes W, Edwards J (2000) Practice guidelines for the treatment of candidiasis. Clin Infect Dis 30:662\u2013678","journal-title":"Clin Infect Dis"},{"key":"2571_CR15","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1086\/380796","volume":"38","author":"Pappas","year":"2004","unstructured":"Pappas P, Rex J, Sobel J, Filler S, Dismukes W, Walsh T, Edwards J (2004) Guidelines for treatment of candidiasis. Clin Infect Dis 38:161\u2013189","journal-title":"Clin Infect Dis"},{"key":"2571_CR16","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1007\/s00134-003-2002-x","volume":"29","author":"Charles","year":"2003","unstructured":"Charles PE, Doise JM, Quenot J, Aube H, Dalle F, Chavanet P, Milesi N, Aho L, Portier H, Blettery B (2003) Candidemia in critically ill patients: difference of outcome between medical and surgical patients. Intensive Care Med 29:2162\u20132169","journal-title":"Intensive Care Med"},{"key":"2571_CR17","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1001\/archinte.1962.03620240029006","volume":"110","author":"McCabe","year":"1962","unstructured":"McCabe W, Jackson G (1962) Gram-negative bacteremia. Arch Intern Med 110:847\u2013855","journal-title":"Arch Intern Med"},{"key":"2571_CR18","doi-asserted-by":"crossref","first-page":"457","DOI":"10.7326\/0003-4819-115-6-457","volume":"115","author":"Bone","year":"1993","unstructured":"Bone R (1993) The pathogenesis of sepsis. Ann Intern Med 115:457\u2013469","journal-title":"Ann Intern Med"},{"key":"2571_CR19","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1086\/323335","volume":"34","author":"Ascioglu","year":"2002","unstructured":"Ascioglu S, Rex J, DePauw B, Bennett J, Bille J, Crokaert F, Denning D, Donnelly J, Edwards J, Erjavec Z, Fiere D, Lortholary O, Maertens J, Meis J, Patterson T, Ritter J, Selleslag D, Shah P, Stevens D, Walsh T (2002) Defining opportunistic invasive fungal infections in immunocompromized patients with cancer and hematopoietic stem cell transplants: an international consensus. Clin Infect Dis 34:7\u201314","journal-title":"Clin Infect Dis"},{"key":"2571_CR20","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s001340050334","volume":"23","author":"Petri","year":"1997","unstructured":"Petri M, Konig J, Moecke H, Gramm H, Barkow H, Kujath P, Dennhart R, Schafer H, Meyer N, Kalmar P, Thulig P, Muller J, Lode H (1997) Epidemiology of invasive mycosis in ICU patients: a prospective multicenter study in 435 non-neutropenic patients. Paul-Ehrlich Society for Chemotherapy, Divisions of Mycology and Pneumonia Research. Intensive Care Med 23:317\u2013325","journal-title":"Intensive Care Med"},{"key":"2571_CR21","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1001\/jama.274.8.639","volume":"274","author":"Vincent","year":"1995","unstructured":"Vincent JL, Bihari D, Suter P, Bruining H, White J, Nicolas-Chanoin M, Wolff M, Spencer R, Hemmer M (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA 274:639\u2013644","journal-title":"JAMA"},{"key":"2571_CR22","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s100960000348","volume":"19","author":"Hedderwick","year":"2000","unstructured":"Hedderwick SA, Lyons MJ, Liu M, Vazquez JA, Kauffman CA (2000) Epidemiology of yeast colonization in the intensive care unit. Eur J Clin Microbiol Infect Dis 19:663\u2013670","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2571_CR23","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1007\/s00134-002-1540-y","volume":"28","author":"Garbino","year":"2002","unstructured":"Garbino J, Lew DP, Romand JA, Hugonnet S, Auckenthaler R, Pittet D (2002) Prevention of severe Candida infections in nonneutropenic, high-risk, critically ill patients: a randomized, double-blind, placebo-controlled trial in patients treated by selective digestive decontamination. Intensive Care Med 28:1708\u20131717","journal-title":"Intensive Care Med"},{"key":"2571_CR24","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s001340050552","volume":"24","author":"Vincent","year":"1998","unstructured":"Vincent JL, Anaissie E, Bruining H, Demajo W, el-Ebiary M, Haber J, Hiramatsu Y, Nitenberg G, Nystrom P, Pittet D, Rogers T, Sandven P, Sganga G, Schaller M, Solomkin J (1998) Epidemiology, diagnosis and treatment of systemic Candida infection in surgical patients under intensive care. Intensive Care Med 24:206\u2013216","journal-title":"Intensive Care Med"},{"key":"2571_CR25","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1086\/313583","volume":"30","author":"Kauffman","year":"2000","unstructured":"Kauffman C, Vazquez J, Sobel J, Gallis H, McKinsey D, Karchmer A, Sugar A, Sharkey P, Wise G, Mangi R, Mosher A, Lee J, Dismukes W (2000) Prospective multicenter surveillance study of funguria in hospitalized patients. Clin Infect Dis 30:14\u201318","journal-title":"Clin Infect Dis"},{"key":"2571_CR26","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/BF01973996","volume":"13","author":"Samonis","year":"1994","unstructured":"Samonis G, Gikas A, Toloudis P, Maraki S, Vrentzos G, Tselentis Y, Bodey G (1994) Prospective study of the impact of broad-spectrum antibiotic on the yeast flora of the human gut. Eur J Clin Microbiol Infect Dis 13:665\u2013667","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2571_CR27","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1097\/00000658-197405000-00024","volume":"179","author":"Stone","year":"1974","unstructured":"Stone H, Kolb L, Currie C, Geheber C, Cuzzell J (1974) Candida sepsis: pathogenesis and principles of treatment. Ann Surg 179:697\u2013710","journal-title":"Ann Surg"},{"key":"2571_CR28","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1093\/jac\/46.6.1001","volume":"46","author":"Laverdi","year":"2000","unstructured":"Laverdi\u00e8re M, Rotstein C, Bow E, Roberts R, Ioannou S, Carr D, Moghaddam N, Group CFS (2000) Impact of fluconazole prophylaxis on fungal colonization and infection rates in neutropenic patients. J Antimicrob Chemother 46:1001\u20131008","journal-title":"J Antimicrob Chemother"},{"key":"2571_CR29","doi-asserted-by":"crossref","unstructured":"Pittet D, Monod M, Filthuth I, Frenk E, Suter PM, Auckenthaler R (1991) Contour-calpmed homogenous electric field gel electrophoresis as a powerful epidemiologic tool in yeast infections. Am J Med 91 [Suppl 3B]:256S\u2013263S","DOI":"10.1016\/0002-9343(91)90378-B"},{"key":"2571_CR30","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0163-4453(03)00120-8","volume":"48","author":"Ibanez-Nolla","year":"2004","unstructured":"Ibanez-Nolla J, Nolla-Salas M, Leon MA, Garcia F, Marrugat J, Soria G, Diaz RM, Torres-Rodrigues JM (2004) Early diagnosis of candidiasis in non-neutropenic critically ill patients. J Infect 48:181\u2013192","journal-title":"J Infect"},{"key":"2571_CR31","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1128\/JCM.36.12.3455-3459.1998","volume":"36","author":"Sandven","year":"1998","unstructured":"Sandven P, Bevanger L, Digranes A, Gaustad P, Haukland H, Steinback M, Group TNYS (1998) The constant low rate of fungemia in Norway, 1991 to 1996. J Clin Microbiol 36:3455\u20133459","journal-title":"J Clin Microbiol"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-005-2571-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-005-2571-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-005-2571-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-005-2571-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T01:17:58Z","timestamp":1744161478000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-005-2571-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,12]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["2571"],"URL":"https:\/\/doi.org\/10.1007\/s00134-005-2571-y","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,12]]},"assertion":[{"value":"9 April 2004","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 January 2005","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 February 2005","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}