{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T14:47:28Z","timestamp":1793285248898,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2006,9,21]],"date-time":"2006-09-21T00:00:00Z","timestamp":1158796800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1007\/s00134-006-0353-9","type":"journal-article","created":{"date-parts":[[2006,10,3]],"date-time":"2006-10-03T05:21:57Z","timestamp":1159852917000},"page":"1937-1944","source":"Crossref","is-referenced-by-count":123,"title":["Transcranial Doppler ultrasonography to confirm brain death: a\u00a0meta-analysis"],"prefix":"10.1007","volume":"32","author":[{"given":"Louisa M.","family":"Monteiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casper W.","family":"Bollen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.","family":"van Huffelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob G. A.","family":"Ackerstaff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolaas J. G.","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrianus J.","family":"van Vught","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,9,21]]},"reference":[{"key":"353_CR1","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1001\/jama.1989.03420150072040","volume":"261","author":"JM Darby","year":"1989","unstructured":"Darby\u00a0JM, Stein\u00a0K, Grenvik\u00a0A, Stuart\u00a0SA (1989) Approach to management of the heartbeating \u201cbrain dead\u201d organ donor. J\u00a0Am Med Assoc 261:2222\u20132228","journal-title":"J Am Med Assoc"},{"key":"353_CR2","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1016\/S0041-1345(97)01146-9","volume":"29","author":"A Lopez-Navidad","year":"1997","unstructured":"Lopez-Navidad\u00a0A, Domingo\u00a0P, Caballero\u00a0F (1997) Organ shortage: viability of potential organ donors and possible loss depend on health care workers who are responsible for the organ procurement program. Transplant Proc 29:3614\u20133616","journal-title":"Transplant Proc"},{"key":"353_CR3","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1212\/WNL.45.5.1003","volume":"45","author":"EF Wijdicks","year":"1995","unstructured":"Wijdicks\u00a0EF (1995) Determining brain death in adults. Neurology 45:1003\u20131011","journal-title":"Neurology"},{"key":"353_CR4","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1001\/jama.1981.03320190042025","volume":"246","author":"Guidelines for the determination of death","year":"1981","unstructured":"Guidelines for the determination of death (1981) Report of the medical consultants on the diagnosis of death to the President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. J\u00a0Am Med Assoc 246:2184\u20132186","journal-title":"J Am Med Assoc"},{"key":"353_CR5","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1212\/WNL.37.6.1077","volume":"37","author":"Task Force for the determination of brain death in children","year":"1987","unstructured":"Guidelines for the determination of brain death in children (1987) Task Force for the determination of brain death in children. Neurology 37:1077\u20131078","journal-title":"Neurology"},{"key":"353_CR6","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1212\/WNL.45.3.585","volume":"45","author":"The Quality Standards Subcommittee of the American Academy of Neurology","year":"1995","unstructured":"Practice parameters for determining brain death in adults (summary statement) (1995) The Quality Standards Subcommittee of the American Academy of Neurology. Neurology 45:1012\u20131014","journal-title":"Neurology"},{"key":"353_CR7","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1001\/jama.1969.03160230039009","volume":"209","author":"D Silverman","year":"1969","unstructured":"Silverman\u00a0D, Saunders\u00a0MG, Schwab\u00a0RS, Masland\u00a0RL (1969) Cerebral death and the electroencephalogram. Report of the ad hoc committee of the American Electroencephalographic Society on EEG Criteria for determination of cerebral death. J\u00a0Am Med Assoc 209:1505\u20131510","journal-title":"J Am Med Assoc"},{"key":"353_CR8","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00004691-199401000-00004","volume":"11","author":"American Electroencephalographic Society","year":"1994","unstructured":"Guideline three: minimum technical standards for EEG recording in suspected cerebral death (1994) American Electroencephalographic Society. J\u00a0Clin Neurophysiol 11:10\u201313","journal-title":"J Clin Neurophysiol"},{"key":"353_CR9","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1001\/jama.1976.03270110021019","volume":"236","author":"DJ Powner","year":"1976","unstructured":"Powner\u00a0DJ (1976) Drug-associated iso-electric EEGs. A\u00a0hazard in brain-death certification. J\u00a0Am Med Assoc 236:1123","journal-title":"J Am Med Assoc"},{"key":"353_CR10","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1001\/jama.1985.03350310083029","volume":"253","author":"RA Mason","year":"1985","unstructured":"Mason\u00a0RA, Arbeit\u00a0LA, Giron\u00a0F (1985) Renal dysfunction after arteriography. J\u00a0Am Med Assoc 253:1001\u20131004","journal-title":"J Am Med Assoc"},{"key":"353_CR11","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1177\/014107688307600415","volume":"76","author":"RR Lewis","year":"1983","unstructured":"Lewis\u00a0RR, Padayachee\u00a0TS, Beasley\u00a0MG, Keen\u00a0H, Gosling\u00a0RG (1983) Investigation of brain death with Doppler-shift ultrasound. J\u00a0R Soc Med 76:308\u2013310","journal-title":"J R Soc Med"},{"key":"353_CR12","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1136\/jnnp.50.11.1504","volume":"50","author":"FJ Kirkham","year":"1987","unstructured":"Kirkham\u00a0FJ, Levin\u00a0SD, Padayachee\u00a0TS, Kyme\u00a0MC, Neville\u00a0BG, Gosling\u00a0RG (1987) Transcranial pulsed Doppler ultrasound findings in brain stem death. J\u00a0Neurol Neurosurg Psychiatry 50:1504\u20131513","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"353_CR13","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1212\/WNL.37.11.1733","volume":"37","author":"AH Ropper","year":"1987","unstructured":"Ropper\u00a0AH, Kehne\u00a0SM, Wechsler\u00a0L (1987) Transcranial Doppler in brain death. Neurology 37:1733\u20131735","journal-title":"Neurology"},{"key":"353_CR14","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1227\/00006123-198904000-00004","volume":"24","author":"DW Newell","year":"1989","unstructured":"Newell\u00a0DW, Grady\u00a0MS, Sirotta\u00a0P, Winn\u00a0HR (1989) Evaluation of brain death using transcranial Doppler. Neurosurgery 24:509\u2013513","journal-title":"Neurosurgery"},{"key":"353_CR15","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1161\/01.STR.5.6.707","volume":"5","author":"S Yoneda","year":"1974","unstructured":"Yoneda\u00a0S, Nishimoto\u00a0A, Nukada\u00a0T, Kuriyama\u00a0Y, Katsurada\u00a0K (1974) To-and-fro movement and external escape of carotid arterial blood in brain death cases. A\u00a0Doppler ultrasonic study. Stroke 5:707\u2013713","journal-title":"Stroke"},{"key":"353_CR16","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1007\/s00134-005-2775-1","volume":"31","author":"LM Monteiro","year":"2005","unstructured":"Monteiro\u00a0LM, Bollen\u00a0CW, Van Huffelen\u00a0AC, Ackerstaff\u00a0RG, Jansen\u00a0NJG, Van Vught\u00a0AJ (2005) Can transcranial Doppler ultrasonography confirm the diagnosis of brain death? Intensive Care Med 31:S1\u2013S174","journal-title":"Intensive Care Med"},{"key":"353_CR17","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1007\/s001340050958","volume":"25","author":"M Hadani","year":"1999","unstructured":"Hadani\u00a0M, Bruk\u00a0B, Ram\u00a0Z, Knoller\u00a0N, Spiegelmann\u00a0R, Segal\u00a0E (1999) Application of transcranial Doppler ultrasonography for the diagnosis of brain death. Intensive Care Med 25:822\u2013828","journal-title":"Intensive Care Med"},{"key":"353_CR18","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1080\/01616412.1991.11740000","volume":"13","author":"Y Zurynski","year":"1991","unstructured":"Zurynski\u00a0Y, Dorsch\u00a0N, Pearson\u00a0I, Choong\u00a0R (1991) Transcranial Doppler ultrasound in brain death: experience in 140 patients. Neurol Res 13:248\u2013252","journal-title":"Neurol Res"},{"key":"353_CR19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1212\/WNL.40.2.300","volume":"40","author":"GW Petty","year":"1990","unstructured":"Petty\u00a0GW, Mohr\u00a0JP, Pedley\u00a0TA, Tatemichi\u00a0TK, Lennihan\u00a0L, Duterte\u00a0DI, Sacco\u00a0RL (1990) The role of transcranial Doppler in confirming brain death: sensitivity, specificity, and suggestions for performance and interpretation. Neurology 40:300\u2013303","journal-title":"Neurology"},{"key":"353_CR20","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/BF01711544","volume":"21","author":"A Paolin","year":"1995","unstructured":"Paolin\u00a0A, Manuali\u00a0A, Paola F di, Boccaletto\u00a0F, Caputo\u00a0P, Zanata\u00a0R, Bardin\u00a0GP, Simini\u00a0G (1995) Reliability in diagnosis of brain death. Intensive Care Med 21:657\u2013662","journal-title":"Intensive Care Med"},{"key":"353_CR21","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1097\/00003246-199407000-00012","volume":"22","author":"M Feri","year":"1994","unstructured":"Feri\u00a0M, Ralli\u00a0L, Felici\u00a0M, Vanni\u00a0D, Capria\u00a0V (1994) Transcranial Doppler and brain death diagnosis. Crit Care Med 22:1120\u20131126","journal-title":"Crit Care Med"},{"key":"353_CR22","first-page":"2391","volume":"27","author":"JM Dominguez-Roldan","year":"1995","unstructured":"Dominguez-Roldan\u00a0JM, Murillo-Cabezas\u00a0F, Munoz-Sanchez\u00a0A, Santamaria-Mifsut\u00a0JL, Villen-Nieto\u00a0J (1995) Changes in the Doppler waveform of intracranial arteries in patients with brain-death status. Transplant Proc 27:2391\u20132392","journal-title":"Transplant Proc"},{"key":"353_CR23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0022-510X(98)00188-9","volume":"160","author":"X Ducrocq","year":"1998","unstructured":"Ducrocq\u00a0X, Braun\u00a0M, Debouverie\u00a0M, Junges\u00a0C, Hummer\u00a0M, Vespignani\u00a0H (1998) Brain death and transcranial Doppler: experience in 130 cases of brain dead patients. J\u00a0Neurol Sci 160:41\u201346","journal-title":"J Neurol Sci"},{"key":"353_CR24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF01793084","volume":"95","author":"van Velthoven","year":"1988","unstructured":"Velthoven van V, Calliauw\u00a0L (1988) Diagnosis of brain death. Transcranial Doppler sonography as an additional method. Acta Neurochir (Wien) 95:57\u201360","journal-title":"Acta Neurochir (Wien)"},{"key":"353_CR25","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1001\/archneur.59.1.58","volume":"59","author":"Y Lample","year":"2002","unstructured":"Lample\u00a0Y, Gilad\u00a0R, Eschel\u00a0Y, Boaz\u00a0M, Rapoport\u00a0A, Sadeh\u00a0M (2002) Diagnosing brain death using the transcranial Doppler with a\u00a0transorbital approach. Arch Neurol 59:58\u201360","journal-title":"Arch Neurol"},{"key":"353_CR26","first-page":"247","volume":"39","author":"SY Qian","year":"1998","unstructured":"Qian\u00a0SY, Fan\u00a0XM, Yin\u00a0HH (1998) Transcranial Doppler assessment of brain death in children. Singapore Med J\u00a039:247\u2013250","journal-title":"Singapore Med J"},{"key":"353_CR27","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/01616412.1990.11739944","volume":"12","author":"T Shiogai","year":"1990","unstructured":"Shiogai\u00a0T, Sato\u00a0E, Tokitsu\u00a0M, Hara\u00a0M, Takeuchi\u00a0K (1990) Transcranial Doppler monitoring in severe brain damage: relationships between intracranial haemodynamics, brain dysfunction and outcome. Neurol Res 12:205\u2013213","journal-title":"Neurol Res"},{"key":"353_CR28","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1227\/00006123-198906000-00015","volume":"24","author":"AD Powers","year":"1989","unstructured":"Powers\u00a0AD, Graeber\u00a0MC, Smith\u00a0RR (1989) Transcranial Doppler ultrasonography in the determination of brain death. Neurosurgery 24:884\u2013889","journal-title":"Neurosurgery"},{"key":"353_CR29","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1136\/jnnp.51.10.1355","volume":"51","author":"H Steinmetz","year":"1988","unstructured":"Steinmetz\u00a0H, Hassler\u00a0W (1988) Reversible intracranial circulatory arrest in acute subarachnoid haemorrhage. J\u00a0Neurol Neurosurg Psychiatry 51:1355\u20131356","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"353_CR30","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1227\/00006123-198804000-00006","volume":"22","author":"E Grote","year":"1988","unstructured":"Grote\u00a0E, Hassler\u00a0W (1988) The critical first minutes after subarachnoid hemorrhage. Neurosurgery 22:654\u2013661","journal-title":"Neurosurgery"},{"key":"353_CR31","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00000542-199301000-00026","volume":"78","author":"CC Eng","year":"1993","unstructured":"Eng\u00a0CC, Lam\u00a0AM, Byrd\u00a0S, Newell\u00a0DW (1993) The diagnosis and management of a\u00a0perianesthetic cerebral aneurysmal rupture aided with transcranial Doppler ultrasonography. Anesthesiology 78:191\u2013194","journal-title":"Anesthesiology"},{"key":"353_CR32","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF00343787","volume":"27","author":"K Vatne","year":"1985","unstructured":"Vatne\u00a0K, Nakstad\u00a0P, Lundar\u00a0T (1985) Digital subtraction angiography (DSA) in the evaluation of brain death. A\u00a0comparison of conventional cerebral angiography with intravenous and intraarterial DSA. Neuroradiology 27:155\u2013157","journal-title":"Neuroradiology"},{"key":"353_CR33","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1191\/0960327104ht478cr","volume":"23","author":"F Marrache","year":"2004","unstructured":"Marrache\u00a0F, Megarbane\u00a0B, Pirnay\u00a0S, Rhaoui\u00a0A, Thuong\u00a0M (2004) Difficulties in assessing brain death in a\u00a0case of benzodiazepine poisoning with persistent cerebral blood flow. Hum Exp Toxicol 23:503\u2013505","journal-title":"Hum Exp Toxicol"},{"issue":"Suppl 7","key":"353_CR34","first-page":"1","volume":"40","author":"O Heiskanen","year":"1964","unstructured":"Heiskanen\u00a0O (1964) Cerebral circulatory arrest caused by acute increase of intracranial pressure. A\u00a0clinical and roentgenological study of 25 cases. Acta Neurol Scand 40(Suppl 7):1\u201357","journal-title":"Acta Neurol Scand"},{"key":"353_CR35","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1055\/s-2008-1063825","volume":"116","author":"JF Spittler","year":"1991","unstructured":"Spittler\u00a0JF, Langenstein\u00a0H (1991) Diagnosis of brain death: limitations of angiography after osteoclastic trepanation. Dtsch Med Wochenschr 116:1828\u20131831","journal-title":"Dtsch Med Wochenschr"},{"key":"353_CR36","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1001\/archneur.1988.00520260117031","volume":"45","author":"LA Alvarez","year":"1988","unstructured":"Alvarez\u00a0LA, Lipton\u00a0RB, Hirschfeld\u00a0A, Salamon\u00a0O, Lantos\u00a0G (1988) Brain death determination by angiography in the setting of a\u00a0skull defect. Arch Neurol 45:225\u2013227","journal-title":"Arch Neurol"},{"key":"353_CR37","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/BF00303573","volume":"9","author":"JM Bray de","year":"1993","unstructured":"de Bray\u00a0JM, Granry\u00a0JC, Monrigal\u00a0JP, Leftheriotis\u00a0G, Saumet\u00a0JL (1993) Effects of thiopental on middle cerebral artery blood velocities: a\u00a0transcranial Doppler study in children. Childs Nerv Syst 9:220\u2013223","journal-title":"Childs Nerv Syst"},{"key":"353_CR38","first-page":"569","volume":"96","author":"SA Rath","year":"1993","unstructured":"Rath\u00a0SA, Richter\u00a0HP (1993) Transcranial Doppler sonography as a\u00a0reliable diagnostic tool in craniocerebral trauma. Unfallchirurg 96:569\u2013575","journal-title":"Unfallchirurg"},{"key":"353_CR39","first-page":"219","volume":"17","author":"T Segura","year":"2002","unstructured":"Segura\u00a0T, Jimenez\u00a0P, Jerez\u00a0P, Garcia\u00a0F, Corcoles\u00a0V (2002) Prolonged clinical pattern of brain death in patients under barbiturate sedation: usefulness of transcranial Doppler. Neurologia 17:219\u2013222","journal-title":"Neurologia"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-006-0353-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00134-006-0353-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-006-0353-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T12:52:14Z","timestamp":1558615934000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00134-006-0353-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9,21]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["353"],"URL":"https:\/\/doi.org\/10.1007\/s00134-006-0353-9","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,9,21]]}}}