{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:21:51Z","timestamp":1792844511744,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T00:00:00Z","timestamp":1534982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1007\/s00134-018-5347-x","type":"journal-article","created":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T05:10:20Z","timestamp":1535001020000},"page":"1483-1492","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients"],"prefix":"10.1007","volume":"44","author":[{"given":"Catherina","family":"Lueck","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Stadler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Koenecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius M.","family":"Hoeper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Dammann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Schneider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan T.","family":"Kielstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold","family":"Ganser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Eder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gernot","family":"Beutel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,23]]},"reference":[{"key":"5347_CR1","doi-asserted-by":"publisher","first-page":"e91","DOI":"10.1016\/S2352-3026(15)00028-9","volume":"2","author":"A Gratwohl","year":"2015","unstructured":"Gratwohl A, Pasquini MC, Aljurf M, Atsuta Y, Baldomero H, Foeken L, Gratwohl M, Bouzas LF, Confer D, Frauendorfer K, Gluckman E, Greinix H, Horowitz M, Iida M, Lipton J, Madrigal A, Mohty M, Noel L, Novitzky N, Nunez J, Oudshoorn M, Passweg J, van Rood J, Szer J, Blume K, Appelbaum FR, Kodera Y, Niederwieser D, Worldwide Network for B, Marrow T (2015) One million haemopoietic stem-cell transplants: a retrospective observational study. Lancet Haematol 2:e91\u2013e100","journal-title":"Lancet Haematol"},{"key":"5347_CR2","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1097\/00003246-198901000-00002","volume":"17","author":"SJ Denardo","year":"1989","unstructured":"Denardo SJ, Oye RK, Bellamy PE (1989) Efficacy of intensive care for bone marrow transplant patients with respiratory failure. Crit Care Med 17:4\u20136","journal-title":"Crit Care Med"},{"key":"5347_CR3","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1038\/bmt.2015.55","volume":"50","author":"E Lengline","year":"2015","unstructured":"Lengline E, Chevret S, Moreau AS, Pene F, Blot F, Bourhis JH, Buzyn A, Schlemmer B, Socie G, Azoulay E (2015) Changes in intensive care for allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant 50:840\u2013845","journal-title":"Bone Marrow Transplant"},{"key":"5347_CR4","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.jcrc.2015.06.020","volume":"30","author":"D Mokart","year":"2015","unstructured":"Mokart D, Granata A, Crocchiolo R, Sannini A, Chow-Chine L, Brun JP, Bisbal M, Faucher M, Faucher C, Blache JL, Castagna L, Furst S, Blaise D (2015) Allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning regimen: outcomes of patients admitted to intensive care unit. J Crit Care 30:1107\u20131113","journal-title":"J Crit Care"},{"key":"5347_CR5","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1200\/JCO.2005.03.9073","volume":"24","author":"F Pene","year":"2006","unstructured":"Pene F, Aubron C, Azoulay E, Blot F, Thiery G, Raynard B, Schlemmer B, Nitenberg G, Buzyn A, Arnaud P, Socie G, Mira JP (2006) Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports. J Clin Oncol 24:643\u2013649","journal-title":"J Clin Oncol"},{"key":"5347_CR6","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1038\/bmt.2015.269","volume":"51","author":"L Platon","year":"2016","unstructured":"Platon L, Amigues L, Ceballos P, Fegueux N, Daubin D, Besnard N, Larcher R, Landreau L, Agostini C, Machado S, Jonquet O, Klouche K (2016) A reappraisal of ICU and long-term outcome of allogeneic hematopoietic stem cell transplantation patients and reassessment of prognosis factors: results of a 5-year cohort study (2009\u20132013). Bone Marrow Transplant 51:256\u2013261","journal-title":"Bone Marrow Transplant"},{"key":"5347_CR7","doi-asserted-by":"publisher","first-page":"R77","DOI":"10.1186\/cc6923","volume":"12","author":"DC Scales","year":"2008","unstructured":"Scales DC, Thiruchelvam D, Kiss A, Sibbald WJ, Redelmeier DA (2008) Intensive care outcomes in bone marrow transplant recipients: a population-based cohort analysis. Crit Care 12:R77","journal-title":"Crit Care"},{"key":"5347_CR8","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/BF00262895","volume":"14","author":"C Torrecilla","year":"1988","unstructured":"Torrecilla C, Cortes JL, Chamorro C, Rubio JJ, Galdos P, Dominguez de Villota E (1988) Prognostic assessment of the acute complications of bone marrow transplantation requiring intensive therapy. Intensive Care Med 14:393\u2013398","journal-title":"Intensive Care Med"},{"key":"5347_CR9","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1038\/bmt.2013.141","volume":"49","author":"R Benz","year":"2014","unstructured":"Benz R, Schanz U, Maggiorini M, Seebach JD, Stussi G (2014) Risk factors for ICU admission and ICU survival after allogeneic hematopoietic SCT. Bone Marrow Transplant 49:62\u201365","journal-title":"Bone Marrow Transplant"},{"key":"5347_CR10","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1097\/01.CCM.0000065761.51367.2D","volume":"31","author":"B Afessa","year":"2003","unstructured":"Afessa B, Tefferi A, Dunn WF, Litzow MR, Peters SG (2003) Intensive care unit support and acute physiology and chronic health evaluation III performance in hematopoietic stem cell transplant recipients. Crit Care Med 31:1715\u20131721","journal-title":"Crit Care Med"},{"key":"5347_CR11","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1038\/sj.bmt.1701158","volume":"21","author":"SR Jackson","year":"1998","unstructured":"Jackson SR, Tweeddale MG, Barnett MJ, Spinelli JJ, Sutherland HJ, Reece DE, Klingemann HG, Nantel SH, Fung HC, Toze CL, Phillips GL, Shepherd JD (1998) Admission of bone marrow transplant recipients to the intensive care unit: outcome, survival and prognostic factors. Bone Marrow Transplant 21:697\u2013704","journal-title":"Bone Marrow Transplant"},{"key":"5347_CR12","doi-asserted-by":"publisher","first-page":"2091","DOI":"10.1056\/NEJMoa1004383","volume":"363","author":"TA Gooley","year":"2010","unstructured":"Gooley TA, Chien JW, Pergam SA, Hingorani S, Sorror ML, Boeckh M, Martin PJ, Sandmaier BM, Marr KA, Appelbaum FR, Storb R, McDonald GB (2010) Reduced mortality after allogeneic hematopoietic-cell transplantation. N Engl J Med 363:2091\u20132101","journal-title":"N Engl J Med"},{"key":"5347_CR13","doi-asserted-by":"publisher","first-page":"R81","DOI":"10.1186\/cc12695","volume":"17","author":"JE Zimmerman","year":"2013","unstructured":"Zimmerman JE, Kramer AA, Knaus WA (2013) Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012. Crit Care 17:R81","journal-title":"Crit Care"},{"key":"5347_CR14","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1007\/s00134-014-3354-0","volume":"40","author":"E Azoulay","year":"2014","unstructured":"Azoulay E, Lemiale V, Mokart D, Pene F, Kouatchet A, Perez P, Vincent F, Mayaux J, Benoit D, Bruneel F, Meert AP, Nyunga M, Rabbat A, Darmon M (2014) Acute respiratory distress syndrome in patients with malignancies. Intensive Care Med 40:1106\u20131114","journal-title":"Intensive Care Med"},{"key":"5347_CR15","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1097\/CCM.0B013E318165314B","volume":"36","author":"F Pene","year":"2008","unstructured":"Pene F, Percheron S, Lemiale V, Viallon V, Claessens YE, Marque S, Charpentier J, Angus DC, Cariou A, Chiche JD, Mira JP (2008) Temporal changes in management and outcome of septic shock in patients with malignancies in the intensive care unit. Crit Care Med 36:690\u2013696","journal-title":"Crit Care Med"},{"key":"5347_CR16","doi-asserted-by":"publisher","first-page":"2810","DOI":"10.1200\/JCO.2012.47.2365","volume":"31","author":"E Azoulay","year":"2013","unstructured":"Azoulay E, Mokart D, Pene F, Lambert J, Kouatchet A, Mayaux J, Vincent F, Nyunga M, Bruneel F, Laisne LM, Rabbat A, Lebert C, Perez P, Chaize M, Renault A, Meert AP, Benoit D, Hamidfar R, Jourdain M, Darmon M, Schlemmer B, Chevret S, Lemiale V (2013) Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium-a groupe de recherche respiratoire en reanimation onco-hematologique study. J Clin Oncol 31:2810\u20132818","journal-title":"J Clin Oncol"},{"key":"5347_CR17","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1080\/10428194.2016.1195499","volume":"58","author":"S Mayer","year":"2016","unstructured":"Mayer S, Pastores SM, Riedel E, Maloy M, Jakubowski AA (2016) Short- and long-term outcomes of adult allogeneic hematopoietic stem cell transplant patients admitted to the intensive care unit in the peritransplant period. Leuk Lymphoma 58:382\u2013390","journal-title":"Leuk Lymphoma"},{"issue":"Suppl 3","key":"5347_CR18","first-page":"1","volume":"39","author":"CSM Lueck","year":"2016","unstructured":"Lueck CSM, Koenecke C, Hoeper MM, Dammann E, Schneider AS, Kielstein JT, Ganser A, Eder M, Beutel G (2016) \u201cOutcome of allogeneic stem cell recipients admitted to the ICU-a single center analysis of 942 patients\u201c-Jahrestagung der Deutschen, Osterreichischen und Schweizerischen Gesellschaften fur Hamatologie und Medizinische Onkologie Leipzig, 14\u201318. Oktober, Abstracts. Oncol Res Treat 39(Suppl 3):1\u2013348","journal-title":"Oncol Res Treat"},{"key":"5347_CR19","doi-asserted-by":"publisher","first-page":"1435","DOI":"10.1007\/s00277-016-2711-1","volume":"95","author":"AJ Ullmann","year":"2016","unstructured":"Ullmann AJ, Schmidt-Hieber M, Bertz H, Heinz WJ, Kiehl M, Kruger W, Mousset S, Neuburger S, Neumann S, Penack O, Silling G, Vehreschild JJ, Einsele H, Maschmeyer G, Infectious Diseases Working Party of the German Society for H, Medical O, the D-K (2016) Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016. Ann Hematol 95:1435\u20131455","journal-title":"Ann Hematol"},{"key":"5347_CR20","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1056\/NEJM197504242921706","volume":"292","author":"ED Thomas","year":"1975","unstructured":"Thomas ED, Storb R, Clift RA, Fefer A, Johnson L, Neiman PE, Lerner KG, Glucksberg H, Buckner CD (1975) Bone-marrow transplantation (second of two parts). N Engl J Med 292:895\u2013902","journal-title":"N Engl J Med"},{"key":"5347_CR21","doi-asserted-by":"publisher","first-page":"4715","DOI":"10.1002\/cncr.24531","volume":"115","author":"A Gratwohl","year":"2009","unstructured":"Gratwohl A, Stern M, Brand R, Apperley J, Baldomero H, de Witte T, Dini G, Rocha V, Passweg J, Sureda A, Tichelli A, Niederwieser D, European Group for B, Marrow T, the European Leukemia N (2009) Risk score for outcome after allogeneic hematopoietic stem cell transplantation: a retrospective analysis. Cancer 115:4715\u20134726","journal-title":"Cancer"},{"key":"5347_CR22","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1002\/1097-0142(194811)1:4<634::AID-CNCR2820010410>3.0.CO;2-L","volume":"1","author":"AW Karnofsky DA","year":"1948","unstructured":"DA Karnofsky AW, Craver LF, Burchenal JH (1948) The use of the nitrogen mustards in the palliative treatment of carcinoma\u2014with particular reference to bronchogenic carcinoma. Cancer 1:634\u2013656","journal-title":"Cancer"},{"key":"5347_CR23","doi-asserted-by":"crossref","unstructured":"Outcomes KDIG (2012) Section\u00a02: AKI definition. Kidney Int Suppl (2011) 2:19\u201336","DOI":"10.1038\/kisup.2011.32"},{"key":"5347_CR24","doi-asserted-by":"publisher","first-page":"2957","DOI":"10.1001\/jama.1993.03510240069035","volume":"270","author":"JR Gall Le","year":"1993","unstructured":"Le Gall JR, Lemeshow S, Saulnier F (1993) A new simplified acute physiology score (SAPS II) based on a European\/North American multicenter study. JAMA 270:2957\u20132963","journal-title":"JAMA"},{"key":"5347_CR25","doi-asserted-by":"crossref","unstructured":"Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G, International sepsis definitions C (2003) 2001 SCCM\/ESICM\/ACCP\/ATS\/SIS International Sepsis Definitions Conference. Intensive Care Med 29:530\u2013538","DOI":"10.1007\/s00134-003-1662-x"},{"key":"5347_CR26","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1111\/bjh.12294","volume":"161","author":"WM Townsend","year":"2013","unstructured":"Townsend WM, Holroyd A, Pearce R, Mackinnon S, Naik P, Goldstone AH, Linch DC, Peggs KS, Thomson KJ, Singer M, Howell DC, Morris EC (2013) Improved intensive care unit survival for critically ill allogeneic haematopoietic stem cell transplant recipients following reduced intensity conditioning. Br J Haematol 161:578\u2013586","journal-title":"Br J Haematol"},{"key":"5347_CR27","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/2110-5820-1-5","volume":"1","author":"E Azoulay","year":"2011","unstructured":"Azoulay E, Soares M, Darmon M, Benoit D, Pastores S, Afessa B (2011) Intensive care of the cancer patient: recent achievements and remaining challenges. Ann Intensive Care 1:5","journal-title":"Ann Intensive Care"},{"key":"5347_CR28","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1007\/BF01709751","volume":"22","author":"JL Vincent","year":"1996","unstructured":"Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction\/failure. On behalf of the working group on sepsis-related problems of the European society of intensive care medicine. Intensive Care Med 22:707\u2013710","journal-title":"Intensive Care Med"},{"key":"5347_CR29","doi-asserted-by":"publisher","first-page":"1050","DOI":"10.1038\/bmt.2016.72","volume":"51","author":"C Saillard","year":"2016","unstructured":"Saillard C, Blaise D, Mokart D (2016) Critically ill allogeneic hematopoietic stem cell transplantation patients in the intensive care unit: reappraisal of actual prognosis. Bone Marrow Transplant 51:1050\u20131061","journal-title":"Bone Marrow Transplant"},{"key":"5347_CR30","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1097\/TP.0000000000001143","volume":"101","author":"C Orvain","year":"2017","unstructured":"Orvain C, Beloncle F, Hamel JF, Thepot S, Mercier M, Kouatchet A, Farhi J, Francois S, Guardiola P, Asfar P, Hunault-Berger M, Mercat A, Ifrah N, Tanguy-Schmidt A (2017) Different impact of the number of organ failures and graft-versus-host disease on the outcome of allogeneic stem cell transplantation recipients requiring intensive care. Transplantation 101:437\u2013444","journal-title":"Transplantation"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00134-018-5347-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-018-5347-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-018-5347-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T19:03:10Z","timestamp":1566500590000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00134-018-5347-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,23]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["5347"],"URL":"https:\/\/doi.org\/10.1007\/s00134-018-5347-x","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,23]]},"assertion":[{"value":"23 April 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Informed consent for data collection was obtained from all individual participants (according to EBMT Registry forms) and\u00a0approved by the local ethics committee. Our study was performed in accordance with the 1964 Declaration of Helsinki and its later amendments.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent and ethical approval"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}