{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:00:22Z","timestamp":1792144822624,"version":"4.4.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T00:00:00Z","timestamp":1579737600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1007\/s00134-019-05897-3","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T08:03:06Z","timestamp":1579766586000},"page":"771-774","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Why we need safer anticoagulant strategies for patients on short-term percutaneous mechanical circulatory support"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5151-6400","authenticated-orcid":false,"given":"Christophe","family":"Vandenbriele","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Vanassche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,23]]},"reference":[{"key":"5897_CR1","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1007\/s00134-018-5064-5","volume":"44","author":"D Abrams","year":"2018","unstructured":"Abrams D, Garan AR, Abdelbary A, Bacchetta M, Bartlett RH, Beck J, Belohlavek J, Chen YS, Fan E, Ferguson ND, Fowles JA, Fraser J, Gong M, Hassan IF, Hodgson C, Hou X, Hryniewicz K, Ichiba S, Jakobleff WA, Lorusso R, MacLaren G, McGuinness S, Mueller T, Park PK, Peek G, Pellegrino V, Price S, Rosenzweig EB, Sakamoto T, Salazar L, Schmidt M, Slutsky AS, Spaulding C, Takayama H, Takeda K, Vuylsteke A, Combes A, Brodie D, International EN, The Extracorporeal Life Support O (2018) Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive Care Med 44:717\u2013729","journal-title":"Intensive Care Med"},{"key":"5897_CR2","doi-asserted-by":"publisher","first-page":"1447","DOI":"10.1007\/s00134-018-5329-z","volume":"44","author":"F Husain-Syed","year":"2018","unstructured":"Husain-Syed F, Ricci Z, Brodie D, Vincent JL, Ranieri VM, Slutsky AS, Taccone FS, Gattinoni L, Ronco C (2018) Extracorporeal organ support (ECOS) in critical illness and acute kidney injury: from native to artificial organ crosstalk. Intensive Care Med 44:1447\u20131459","journal-title":"Intensive Care Med"},{"key":"5897_CR3","doi-asserted-by":"publisher","first-page":"e332","DOI":"10.1097\/CCM.0000000000003650","volume":"47","author":"C Fisser","year":"2019","unstructured":"Fisser C, Reichenbacher C, Muller T, Schneckenpointner R, Malfertheiner MV, Philipp A, Foltan M, Lunz D, Zeman F, Lubnow M (2019) Incidence and risk factors for cannula-related venous thrombosis after venovenous extracorporeal membrane oxygenation in adult patients with acute respiratory failure. Crit Care Med 47:e332\u2013e339","journal-title":"Crit Care Med"},{"issue":"Suppl 1","key":"5897_CR4","doi-asserted-by":"publisher","first-page":"S336","DOI":"10.1111\/jth.12963","volume":"13","author":"GM Annich","year":"2015","unstructured":"Annich GM (2015) Extracorporeal life support: the precarious balance of hemostasis. J Thromb Haemost 13(Suppl 1):S336\u2013342","journal-title":"J Thromb Haemost"},{"key":"5897_CR5","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1007\/s00134-016-4318-3","volume":"42","author":"CE Luyt","year":"2016","unstructured":"Luyt CE, Brechot N, Demondion P, Jovanovic T, Hekimian G, Lebreton G, Nieszkowska A, Schmidt M, Trouillet JL, Leprince P, Chastre J, Combes A (2016) Brain injury during venovenous extracorporeal membrane oxygenation. Intensive Care Med 42:897\u2013907","journal-title":"Intensive Care Med"},{"key":"5897_CR6","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/j.athoracsur.2013.09.008","volume":"97","author":"R Cheng","year":"2014","unstructured":"Cheng R, Hachamovitch R, Kittleson M, Patel J, Arabia F, Moriguchi J, Esmailian F, Azarbal B (2014) Complications of extracorporeal membrane oxygenation for treatment of cardiogenic shock and cardiac arrest: a meta-analysis of 1866 adult patients. Ann Thorac Surg 97:610\u2013616","journal-title":"Ann Thorac Surg"},{"key":"5897_CR7","doi-asserted-by":"crossref","unstructured":"Protti A, Iapichino GE, Di Nardo M, Panigada M, Gattinoni L, (2019) Anticoagulation management and antithrombin supplementation practice during veno-venous extracorporeal membrane oxygenation: a worldwide survey. Anesthesiology.","DOI":"10.1097\/ALN.0000000000003044"},{"key":"5897_CR8","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1097\/PCC.0000000000000955","volume":"17","author":"TE Wong","year":"2016","unstructured":"Wong TE, Nguyen T, Shah SS, Brogan TV, Witmer CM (2016) Antithrombin concentrate use in pediatric extracorporeal membrane oxygenation: a multicenter cohort study. Pediatr Crit Care Med 17:1170\u20131178","journal-title":"Pediatr Crit Care Med"},{"key":"5897_CR9","doi-asserted-by":"publisher","unstructured":"Arnouk S, Altshuler D, Lewis TC, Merchan C, Smith DE, 3rd, Toy B, Zakhary B, Papadopoulos J (2019) Evaluation of anti-xa and activated partial thromboplastin time monitoring of heparin in adult patients receiving extracorporeal membrane oxygenation support. ASAIO J. https:\/\/doi.org\/10.1097\/MAT.0000000000001004","DOI":"10.1097\/MAT.0000000000001004"},{"key":"5897_CR10","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s13613-017-0352-8","volume":"8","author":"M Panigada","year":"2018","unstructured":"Panigada M, Iapichino GE, Brioni M, Panarello G, Protti A, Grasselli G, Occhipinti G, Novembrino C, Consonni D, Arcadipane A, Gattinoni L, Pesenti A (2018) Thromboelastography-based anticoagulation management during extracorporeal membrane oxygenation: a safety and feasibility pilot study. Ann Intensive Care 8:7","journal-title":"Ann Intensive Care"},{"key":"5897_CR11","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1007\/s00134-018-5346-y","volume":"44","author":"A Kimmoun","year":"2018","unstructured":"Kimmoun A, Oulehri W, Sonneville R, Grisot PH, Zogheib E, Amour J, Aissaoui N, Megarbane B, Mongardon N, Renou A, Schmidt M, Besnier E, Delmas C, Dessertaine G, Guidon C, Nesseler N, Labro G, Rozec B, Pierrot M, Helms J, Bougon D, Chardonnal L, Medard A, Ouattara A, Girerd N, Lamiral Z, Borie M, Ajzenberg N, Levy B (2018) Prevalence and outcome of heparin-induced thrombocytopenia diagnosed under veno-arterial extracorporeal membrane oxygenation: a retrospective nationwide study. Intensive Care Med 44:1460\u20131469","journal-title":"Intensive Care Med"},{"key":"5897_CR12","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1160\/TH16-03-0230","volume":"116","author":"S Selleng","year":"2016","unstructured":"Selleng S, Selleng K (2016) Heparin-induced thrombocytopenia in cardiac surgery and critically ill patients. Thromb Haemost 116:843\u2013851","journal-title":"Thromb Haemost"},{"key":"5897_CR13","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1097\/MAT.0b013e318213f9e0","volume":"57","author":"T Bein","year":"2011","unstructured":"Bein T, Zimmermann M, Philipp A, Ramming M, Sinner B, Schmid C, Muller T, Graf B, Schlitt HJ, Weber-Carstens S (2011) Addition of acetylsalicylic acid to heparin for anticoagulation management during pumpless extracorporeal lung assist. ASAIO J 57:164\u2013168","journal-title":"ASAIO J"},{"key":"5897_CR14","doi-asserted-by":"publisher","first-page":"2251","DOI":"10.1007\/s00134-018-5465-5","volume":"44","author":"P Schellongowski","year":"2018","unstructured":"Schellongowski P, Combes A, Moller MH (2018) Focus on extracorporeal life support. Intensive Care Med 44:2251\u20132253","journal-title":"Intensive Care Med"},{"key":"5897_CR15","first-page":"43","volume":"8","author":"AL Beitelshees","year":"2015","unstructured":"Beitelshees AL, Voora D, Lewis JP (2015) Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics. Pharmgenomics Pers Med 8:43\u201361","journal-title":"Pharmgenomics Pers Med"},{"issue":"Suppl 2","key":"5897_CR16","doi-asserted-by":"publisher","first-page":"S40","DOI":"10.1016\/S0049-3848(16)30363-2","volume":"141","author":"JI Weitz","year":"2016","unstructured":"Weitz JI (2016) Factor XI and factor XII as targets for new anticoagulants. Thromb Res 141(Suppl 2):S40\u201345","journal-title":"Thromb Res"},{"key":"5897_CR17","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1111\/aor.12737","volume":"41","author":"K Krueger","year":"2017","unstructured":"Krueger K, Schmutz A, Zieger B, Kalbhenn J (2017) Venovenous extracorporeal membrane oxygenation with prophylactic subcutaneous anticoagulation only: an observational study in more than 60 patients. Artif Organs 41:186\u2013192","journal-title":"Artif Organs"},{"key":"5897_CR18","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1177\/0885066616656333","volume":"32","author":"F Sanfilippo","year":"2017","unstructured":"Sanfilippo F, Asmussen S, Maybauer DM, Santonocito C, Fraser JF, Erdoes G, Maybauer MO (2017) Bivalirudin for alternative anticoagulation in extracorporeal membrane oxygenation: a systematic review. J Intensive Care Med 32:312\u2013319","journal-title":"J Intensive Care Med"},{"key":"5897_CR19","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s40560-017-0235-y","volume":"5","author":"A Rouge","year":"2017","unstructured":"Rouge A, Pelen F, Durand M, Schwebel C (2017) Argatroban for an alternative anticoagulant in HIT during ECMO. J Intensive Care 5:39","journal-title":"J Intensive Care"},{"key":"5897_CR20","doi-asserted-by":"publisher","first-page":"321","DOI":"10.3389\/fmed.2018.00321","volume":"5","author":"A Ontaneda","year":"2018","unstructured":"Ontaneda A, Annich GM (2018) Novel surfaces in extracorporeal membrane oxygenation circuits. Front Med (Lausanne) 5:321","journal-title":"Front Med (Lausanne)"},{"key":"5897_CR21","doi-asserted-by":"publisher","first-page":"e0159973","DOI":"10.1371\/journal.pone.0159973","volume":"11","author":"DL Staudacher","year":"2016","unstructured":"Staudacher DL, Biever PM, Benk C, Ahrens I, Bode C, Wengenmayer T (2016) Dual Antiplatelet Therapy (DAPT) versus no antiplatelet therapy and incidence of major bleeding in patients on venoarterial extracorporeal membrane oxygenation. PLoS ONE 11:e0159973","journal-title":"PLoS ONE"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-019-05897-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00134-019-05897-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-019-05897-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:33:15Z","timestamp":1611275595000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00134-019-05897-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,23]]},"references-count":21,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["5897"],"URL":"https:\/\/doi.org\/10.1007\/s00134-019-05897-3","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,23]]},"assertion":[{"value":"2 November 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 January 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The author(s) declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}