{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:29:33Z","timestamp":1790375373036,"version":"4.1.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T00:00:00Z","timestamp":1591574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20160637"],"award-info":[{"award-number":["20160637"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004102","name":"Laerdal Foundation for Acute Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s00134-020-06024-3","type":"journal-article","created":{"date-parts":[[2020,6,8]],"date-time":"2020-06-08T06:04:22Z","timestamp":1591596262000},"page":"1361-1370","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Time to intra-arrest therapeutic hypothermia in out-of-hospital cardiac arrest patients and its association with neurologic outcome: a propensity matched sub-analysis of the PRINCESS trial"],"prefix":"10.1007","volume":"46","author":[{"given":"Akil","family":"Awad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio Silvio","family":"Taccone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Jonsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sune","family":"Forsberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Hollenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anatolij","family":"Truhlar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattias","family":"Ringh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin S.","family":"Abella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lance B.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Vincent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7432-1673","authenticated-orcid":false,"given":"Per","family":"Nordberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"6024_CR1","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/j.resuscitation.2015.07.018","volume":"95","author":"JP Nolan","year":"2015","unstructured":"Nolan JP, Soar J, Cariou A, Cronberg T, Moulaert VR, Deakin CD, Bottiger BW, Friberg H, Sunde K, Sandroni C (2015) European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation 95:202\u2013222. https:\/\/doi.org\/10.1016\/j.resuscitation.2015.07.018","journal-title":"Resuscitation"},{"issue":"18 Suppl 2","key":"6024_CR2","doi-asserted-by":"publisher","first-page":"S465","DOI":"10.1161\/cir.0000000000000262","volume":"132","author":"CW Callaway","year":"2015","unstructured":"Callaway CW, Donnino MW, Fink EL, Geocadin RG, Golan E, Kern KB, Leary M, Meurer WJ, Peberdy MA, Thompson TM, Zimmerman JL (2015) Part 8: Post-Cardiac Arrest Care: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 132(18 Suppl 2):S465\u2013482. https:\/\/doi.org\/10.1161\/cir.0000000000000262","journal-title":"Circulation"},{"issue":"9","key":"6024_CR3","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1007\/s00134-019-05666-2","volume":"45","author":"C Sandroni","year":"2019","unstructured":"Sandroni C, Combes A, Nolan JP (2019) Focus on post-resuscitation care. Intensive Care Med 45(9):1283\u20131287. https:\/\/doi.org\/10.1007\/s00134-019-05666-2","journal-title":"Intensive Care Med"},{"issue":"10","key":"6024_CR4","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.1007\/s00134-015-3788-z","volume":"41","author":"A Cariou","year":"2015","unstructured":"Cariou A, Nolan JP, Sunde K (2015) Ten strategies to increase survival of cardiac arrest patients. Intensive Care Med 41(10):1820\u20131823. https:\/\/doi.org\/10.1007\/s00134-015-3788-z","journal-title":"Intensive Care Med"},{"issue":"12","key":"6024_CR5","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1007\/s00134-018-5453-9","volume":"44","author":"P Jakkula","year":"2018","unstructured":"Jakkula P, Reinikainen M, Hastbacka J, Loisa P, Tiainen M, Pettila V, Toppila J, Lahde M, Backlund M, Okkonen M, Bendel S, Birkelund T, Pulkkinen A, Heinonen J, Tikka T, Skrifvars MB (2018) Targeting two different levels of both arterial carbon dioxide and arterial oxygen after cardiac arrest and resuscitation: a randomised pilot trial. Intensive Care Med 44(12):2112\u20132121. https:\/\/doi.org\/10.1007\/s00134-018-5453-9","journal-title":"Intensive Care Med"},{"issue":"1\u20132","key":"6024_CR6","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.jns.2007.04.042","volume":"261","author":"MT Froehler","year":"2007","unstructured":"Froehler MT, Geocadin RG (2007) Hypothermia for neuroprotection after cardiac arrest: mechanisms, clinical trials and patient care. J Neurol Sci 261(1\u20132):118\u2013126. https:\/\/doi.org\/10.1016\/j.jns.2007.04.042","journal-title":"J Neurol Sci"},{"issue":"6","key":"6024_CR7","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1097\/CCM.0b013e318212020a","volume":"39","author":"D Che","year":"2011","unstructured":"Che D, Li L, Kopil CM, Liu Z, Guo W, Neumar RW (2011) Impact of therapeutic hypothermia onset and duration on survival, neurologic function, and neurodegeneration after cardiac arrest. Crit Care Med 39(6):1423\u20131430. https:\/\/doi.org\/10.1097\/CCM.0b013e318212020a","journal-title":"Crit Care Med"},{"issue":"22","key":"6024_CR8","doi-asserted-by":"publisher","first-page":"2786","DOI":"10.1161\/01.Cir.0000131940.19833.85","volume":"109","author":"BS Abella","year":"2004","unstructured":"Abella BS, Zhao D, Alvarado J, Hamann K, Vanden Hoek TL, Becker LB (2004) Intra-arrest cooling improves outcomes in a murine cardiac arrest model. Circulation 109(22):2786\u20132791. https:\/\/doi.org\/10.1161\/01.Cir.0000131940.19833.85","journal-title":"Circulation"},{"issue":"23","key":"6024_CR9","doi-asserted-by":"publisher","first-page":"2690","DOI":"10.1161\/circulationaha.106.613349","volume":"113","author":"A Nozari","year":"2006","unstructured":"Nozari A, Safar P, Stezoski SW, Wu X, Kostelnik S, Radovsky A, Tisherman S, Kochanek PM (2006) Critical time window for intra-arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation. Circulation 113(23):2690\u20132696. https:\/\/doi.org\/10.1161\/circulationaha.106.613349","journal-title":"Circulation"},{"issue":"2","key":"6024_CR10","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.resuscitation.2007.10.015","volume":"77","author":"D Zhao","year":"2008","unstructured":"Zhao D, Abella BS, Beiser DG, Alvarado JP, Wang H, Hamann KJ, Hoek TL, Becker LB (2008) Intra-arrest cooling with delayed reperfusion yields higher survival than earlier normothermic resuscitation in a mouse model of cardiac arrest. Resuscitation 77(2):242\u2013249. https:\/\/doi.org\/10.1016\/j.resuscitation.2007.10.015","journal-title":"Resuscitation"},{"issue":"5","key":"6024_CR11","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.resuscitation.2010.01.027","volume":"81","author":"H Wang","year":"2010","unstructured":"Wang H, Barbut D, Tsai MS, Sun S, Weil MH, Tang W (2010) Intra-arrest selective brain cooling improves success of resuscitation in a porcine model of prolonged cardiac arrest. Resuscitation 81(5):617\u2013621. https:\/\/doi.org\/10.1016\/j.resuscitation.2010.01.027","journal-title":"Resuscitation"},{"issue":"9","key":"6024_CR12","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1097\/00003246-199309000-00019","volume":"21","author":"K Kuboyama","year":"1993","unstructured":"Kuboyama K, Safar P, Radovsky A, Tisherman SA, Stezoski SW, Alexander H (1993) Delay in cooling negates the beneficial effect of mild resuscitative cerebral hypothermia after cardiac arrest in dogs: a prospective, randomized study. Crit Care Med 21(9):1348\u20131358","journal-title":"Crit Care Med"},{"issue":"23","key":"6024_CR13","doi-asserted-by":"publisher","first-page":"2197","DOI":"10.1056\/NEJMoa1310519","volume":"369","author":"N Nielsen","year":"2013","unstructured":"Nielsen N, Wetterslev J, Cronberg T, Erlinge D, Gasche Y, Hassager C, Horn J, Hovdenes J, Kjaergaard J, Kuiper M, Pellis T, Stammet P, Wanscher M, Wise MP, Aneman A, Al-Subaie N, Boesgaard S, Bro-Jeppesen J, Brunetti I, Bugge JF, Hingston CD, Juffermans NP, Koopmans M, Kober L, Langorgen J, Lilja G, Moller JE, Rundgren M, Rylander C, Smid O, Werer C, Winkel P, Friberg H (2013) Targeted temperature management at 33\u00b0C versus 36\u00b0C after cardiac arrest. New Engl J Med 369(23):2197\u20132206. https:\/\/doi.org\/10.1056\/NEJMoa1310519","journal-title":"New Engl J Med"},{"issue":"8","key":"6024_CR14","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1056\/NEJMoa012689","volume":"346","author":"HACA-group","year":"2002","unstructured":"HACA-group (2002) Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. New Engl J Med 346(8):549\u2013556. https:\/\/doi.org\/10.1056\/NEJMoa012689","journal-title":"New Engl J Med"},{"issue":"8","key":"6024_CR15","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1056\/NEJMoa003289","volume":"346","author":"SA Bernard","year":"2002","unstructured":"Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, Smith K (2002) Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. New Engl J Med 346(8):557\u2013563. https:\/\/doi.org\/10.1056\/NEJMoa003289","journal-title":"New Engl J Med"},{"issue":"1","key":"6024_CR16","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1001\/jama.2013.282173","volume":"311","author":"F Kim","year":"2014","unstructured":"Kim F, Nichol G, Maynard C, Hallstrom A, Kudenchuk PJ, Rea T, Copass MK, Carlbom D, Deem S, Longstreth WT Jr, Olsufka M, Cobb LA (2014) Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. JAMA 311(1):45\u201352. https:\/\/doi.org\/10.1001\/jama.2013.282173","journal-title":"JAMA"},{"issue":"11","key":"6024_CR17","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1161\/circulationaha.116.021989","volume":"134","author":"SA Bernard","year":"2016","unstructured":"Bernard SA, Smith K, Finn J, Hein C, Grantham H, Bray JE, Deasy C, Stephenson M, Williams TA, Straney LD, Brink D, Larsen R, Cotton C, Cameron P (2016) Induction of therapeutic hypothermia during out-of-hospital cardiac arrest using a rapid infusion of cold saline: the RINSE trial (rapid infusion of cold normal saline). Circulation 134(11):797\u2013805. https:\/\/doi.org\/10.1161\/circulationaha.116.021989","journal-title":"Circulation"},{"issue":"12","key":"6024_CR18","doi-asserted-by":"publisher","first-page":"1832","DOI":"10.1007\/s00134-014-3519-x","volume":"40","author":"G Debaty","year":"2014","unstructured":"Debaty G, Maignan M, Savary D, Koch FX, Ruckly S, Durand M, Picard J, Escallier C, Chouquer R, Santre C, Minet C, Guergour D, Hammer L, Bouvaist H, Belle L, Adrie C, Payen JF, Carpentier F, Gueugniaud PY, Danel V, Timsit JF (2014) Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial. Intensive Care Med 40(12):1832\u20131842. https:\/\/doi.org\/10.1007\/s00134-014-3519-x","journal-title":"Intensive Care Med"},{"issue":"1","key":"6024_CR19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1161\/01.cir.69.1.181","volume":"69","author":"RV Ditchey","year":"1984","unstructured":"Ditchey RV, Lindenfeld J (1984) Potential adverse effects of volume loading on perfusion of vital organs during closed-chest resuscitation. Circulation 69(1):181\u2013189. https:\/\/doi.org\/10.1161\/01.cir.69.1.181","journal-title":"Circulation"},{"issue":"14","key":"6024_CR20","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1161\/circulationaha.109.848424","volume":"120","author":"D Yannopoulos","year":"2009","unstructured":"Yannopoulos D, Zviman M, Castro V, Kolandaivelu A, Ranjan R, Wilson RF, Halperin HR (2009) Intra-cardiopulmonary resuscitation hypothermia with and without volume loading in an ischemic model of cardiac arrest. Circulation 120(14):1426\u20131435. https:\/\/doi.org\/10.1161\/circulationaha.109.848424","journal-title":"Circulation"},{"issue":"7","key":"6024_CR21","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1161\/circulationaha.109.931691","volume":"122","author":"M Castren","year":"2010","unstructured":"Castren M, Nordberg P, Svensson L, Taccone F, Vincent JL, Desruelles D, Eichwede F, Mols P, Schwab T, Vergnion M, Storm C, Pesenti A, Pachl J, Guerisse F, Elste T, Roessler M, Fritz H, Durnez P, Busch HJ, Inderbitzen B, Barbut D (2010) Intra-arrest transnasal evaporative cooling: a randomized, prehospital, multicenter study (PRINCE: Pre-ROSC IntraNasal Cooling Effectiveness). Circulation 122(7):729\u2013736. https:\/\/doi.org\/10.1161\/circulationaha.109.931691","journal-title":"Circulation"},{"key":"6024_CR22","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1471-227x-13-21","volume":"13","author":"P Nordberg","year":"2013","unstructured":"Nordberg P, Taccone FS, Castren M, Truhlar A, Desruelles D, Forsberg S, Hollenberg J, Vincent JL, Svensoon L (2013) Design of the PRINCESS trial: pre-hospital resuscitation intra-nasal cooling effectiveness survival study (PRINCESS). BMC emergency medicine 13:21. https:\/\/doi.org\/10.1186\/1471-227x-13-21","journal-title":"BMC emergency medicine"},{"issue":"8","key":"6024_CR23","doi-asserted-by":"publisher","first-page":"2164","DOI":"10.1161\/strokeaha.110.613000","volume":"42","author":"A Abou-Chebl","year":"2011","unstructured":"Abou-Chebl A, Sung G, Barbut D, Torbey M (2011) Local brain temperature reduction through intranasal cooling with the RhinoChill device: preliminary safety data in brain-injured patients. Stroke 42(8):2164\u20132169. https:\/\/doi.org\/10.1161\/strokeaha.110.613000","journal-title":"Stroke"},{"issue":"17","key":"6024_CR24","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1001\/jama.2019.4149","volume":"321","author":"P Nordberg","year":"2019","unstructured":"Nordberg P, Taccone FS, Truhlar A, Forsberg S, Hollenberg J, Jonsson M, Cuny J, Goldstein P, Vermeersch N, Higuet A, Jimenes FC, Ortiz FR, Williams J, Desruelles D, Creteur J, Dillenbeck E, Busche C, Busch HJ, Ringh M, Konrad D, Peterson J, Vincent JL, Svensson L (2019) Effect of trans-nasal evaporative intra-arrest cooling on functional neurologic outcome in out-of-hospital cardiac arrest: the PRINCESS randomized clinical trial. JAMA 321(17):1677\u20131685. https:\/\/doi.org\/10.1001\/jama.2019.4149","journal-title":"JAMA"},{"key":"6024_CR25","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.resuscitation.2014.11.002","volume":"96","author":"GD Perkins","year":"2015","unstructured":"Perkins GD, Jacobs IG, Nadkarni VM, Berg RA, Bhanji F, Biarent D, Bossaert LL, Brett SJ, Chamberlain D, de Caen AR, Deakin CD, Finn JC, Grasner JT, Hazinski MF, Iwami T, Koster RW, Lim SH, Ma MH, McNally BF, Morley PT, Morrison LJ, Monsieurs KG, Montgomery W, Nichol G, Okada K, Ong ME, Travers AH, Nolan JP (2015) Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Templates for Out-of-Hospital Cardiac Arrest: A Statement for Healthcare Professionals From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); and the American Heart Association Emergency Cardiovascular Care Committee and the Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation. Resuscitation 96:328\u2013340. https:\/\/doi.org\/10.1016\/j.resuscitation.2014.11.002","journal-title":"Resuscitation"},{"issue":"7905","key":"6024_CR26","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1016\/S0140-6736(75)92830-5","volume":"1","author":"B Jennett","year":"1975","unstructured":"Jennett B, Bond M (1975) Assessment of outcome after severe brain damage. Lancet (London, England) 1(7905):480\u2013484","journal-title":"Lancet (London, England)"},{"issue":"3","key":"6024_CR27","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.resuscitation.2011.10.026","volume":"83","author":"J Benz-Woerner","year":"2012","unstructured":"Benz-Woerner J, Delodder F, Benz R, Cueni-Villoz N, Feihl F, Rossetti AO, Liaudet L, Oddo M (2012) Body temperature regulation and outcome after cardiac arrest and therapeutic hypothermia. Resuscitation 83(3):338\u2013342. https:\/\/doi.org\/10.1016\/j.resuscitation.2011.10.026","journal-title":"Resuscitation"},{"issue":"3","key":"6024_CR28","doi-asserted-by":"publisher","first-page":"R121","DOI":"10.1186\/cc9077","volume":"14","author":"AW den Hartog","year":"2010","unstructured":"den Hartog AW, de Pont AC, Robillard LB, Binnekade JM, Schultz MJ, Horn J (2010) Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study. Crit Care 14(3):R121. https:\/\/doi.org\/10.1186\/cc9077","journal-title":"Crit Care"},{"key":"6024_CR29","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1906661","author":"JB Lascarrou","year":"2019","unstructured":"Lascarrou JB, Merdji H, Le Gouge A, Colin G, Grillet G, Girardie P, Coupez E, Dequin PF, Cariou A, Boulain T, Brule N, Frat JP, Asfar P, Pichon N, Landais M, Plantefeve G, Quenot JP, Chakarian JC, Sirodot M, Legriel S, Letheulle J, Thevenin D, Desachy A, Delahaye A, Botoc V, Vimeux S, Martino F, Giraudeau B, Reignier J (2019) Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm. New Engl J Med. https:\/\/doi.org\/10.1056\/NEJMoa1906661","journal-title":"New Engl J Med"},{"issue":"8","key":"6024_CR30","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/j.resuscitation.2012.03.039","volume":"83","author":"J Kreutziger","year":"2012","unstructured":"Kreutziger J, Wenzel V (2012) Shape and size of cardiopulmonary resuscitation trials to optimise impact of advanced life support interventions. Resuscitation 83(8):923\u2013924. https:\/\/doi.org\/10.1016\/j.resuscitation.2012.03.039","journal-title":"Resuscitation"},{"issue":"9","key":"6024_CR31","doi-asserted-by":"publisher","first-page":"e517","DOI":"10.1161\/cir.0000000000000702","volume":"140","author":"RG Geocadin","year":"2019","unstructured":"Geocadin RG, Callaway CW, Fink EL, Golan E, Greer DM, Ko NU, Lang E, Licht DJ, Marino BS, McNair ND, Peberdy MA, Perman SM, Sims DB, Soar J, Sandroni C (2019) Standards for studies of neurological prognostication in comatose survivors of cardiac arrest: a scientific statement from the American Heart Association. Circulation 140(9):e517\u2013e542. https:\/\/doi.org\/10.1161\/cir.0000000000000702","journal-title":"Circulation"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-020-06024-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-020-06024-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-020-06024-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T23:33:43Z","timestamp":1623108823000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-020-06024-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":31,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["6024"],"URL":"https:\/\/doi.org\/10.1007\/s00134-020-06024-3","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]},"assertion":[{"value":"29 December 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"During the PRINCESS trail, Dr Nordberg reported grants from Swedish Heart\u2013Lung Foundation and the Laerdal Foundation and nonfinancial support from BrainCool AB during the conduct of the study (i.e., providing the cooling devices during the study period at no cost). Dr Taccone reported personal fees from BARD outside the submitted work. Dr Abella reports an educational grant and consulting fees from Becton Dickinson, as well as grant funding from the NIH and PCORI. Dr. Truhlar reported nonfinancial support from the Karolinska Institute during the conduct of the study. Dr. Svensson reported grants from the Swedish Heart and Lung Foundation. No other disclosures in relation to this sub-analysis of PRINCESS trial data were reported.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}