{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:58:10Z","timestamp":1792810690504,"version":"4.5.0"},"reference-count":139,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T00:00:00Z","timestamp":1625616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s00134-021-06459-2","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T08:02:56Z","timestamp":1625644976000},"page":"851-866","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":255,"title":["Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS"],"prefix":"10.1007","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-6308","authenticated-orcid":false,"given":"Domenico Luca","family":"Grieco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore Maurizio","family":"Maggiore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oriol","family":"Roca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Spinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhakti K.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud W.","family":"Thille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen S\u00edlvia V.","family":"Barbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Garcia","family":"de Acilu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore Lucio","family":"Cutuli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Bongiovanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Amato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Frat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Mauri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Kress","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Mancebo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,7]]},"reference":[{"key":"6459_CR1","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1001\/jama.2016.0291","volume":"315","author":"G Bellani","year":"2016","unstructured":"Bellani G, Laffey JG, Pham T et al (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315:788\u2013800. https:\/\/doi.org\/10.1001\/jama.2016.0291","journal-title":"JAMA"},{"key":"6459_CR2","doi-asserted-by":"publisher","first-page":"2184","DOI":"10.1007\/s00134-020-06245-6","volume":"46","author":"ND Ferguson","year":"2020","unstructured":"Ferguson ND, Pham T, Gong MN (2020) How severe COVID-19 infection is changing ARDS management. Intensive Care Med 46:2184\u20132186. https:\/\/doi.org\/10.1007\/s00134-020-06245-6","journal-title":"Intensive Care Med"},{"key":"6459_CR3","doi-asserted-by":"publisher","first-page":"2131","DOI":"10.1007\/s00134-020-06298-7","volume":"46","author":"S Jaber","year":"2020","unstructured":"Jaber S, Citerio G, Slutsky AS (2020) Acute respiratory failure and mechanical ventilation in the context of the COVID-19 pandemic: why a special issue in ICM? Intensive Care Med 46:2131\u20132132. https:\/\/doi.org\/10.1007\/s00134-020-06298-7","journal-title":"Intensive Care Med"},{"key":"6459_CR4","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1001\/jama.2020.3633","volume":"323","author":"S Murthy","year":"2020","unstructured":"Murthy S, Gomersall CD, Fowler RA (2020) Care for critically Ill patients with COVID-19. JAMA 323:1499\u20131500. https:\/\/doi.org\/10.1001\/jama.2020.3633","journal-title":"JAMA"},{"key":"6459_CR5","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1001\/jama.2012.5669","volume":"307","author":"ARDS Definition Task Force","year":"2012","unstructured":"Definition Task Force ARDS, Ranieri VM, Rubenfeld GD et al (2012) Acute respiratory distress syndrome: the Berlin Definition. JAMA 307:2526\u20132533. https:\/\/doi.org\/10.1001\/jama.2012.5669","journal-title":"JAMA"},{"key":"6459_CR6","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03317-2020","volume-title":"Outcome of Acute Hypoxaemic Respiratory Failure","author":"T Pham","year":"2020","unstructured":"Pham T, Pesenti A, Bellani G et al (2020) Outcome of Acute Hypoxaemic Respiratory Failure. Eur Respir J, Insights from the Lung Safe Study. https:\/\/doi.org\/10.1183\/13993003.03317-2020"},{"key":"6459_CR7","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1164\/rccm.201606-1306OC","volume":"195","author":"G Bellani","year":"2017","unstructured":"Bellani G, Laffey JG, Pham T et al (2017) Noninvasive ventilation of patients with acute respiratory distress syndrome. Insights from the LUNG SAFE Study. Am J Respir Crit Care Med 195:67\u201377. https:\/\/doi.org\/10.1164\/rccm.201606-1306OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR8","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1164\/rccm.202005-1582LE","volume":"202","author":"P Esnault","year":"2020","unstructured":"Esnault P, Cardinale M, Hraiech S et al (2020) High respiratory drive and excessive respiratory efforts predict relapse of respiratory failure in critically Ill patients with COVID-19. Am J Respir Crit Care Med 202:1173\u20131178. https:\/\/doi.org\/10.1164\/rccm.202005-1582LE","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR9","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1164\/rccm.201912-2512OC","volume":"202","author":"R Tonelli","year":"2020","unstructured":"Tonelli R, Fantini R, Tabb\u00ec L et al (2020) Early inspiratory effort assessment by esophageal manometry predicts noninvasive ventilation outcome in de novo respiratory failure. A pilot study. Am J Respir Crit Care Med 202:558\u2013567. https:\/\/doi.org\/10.1164\/rccm.201912-2512OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR10","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1164\/rccm.201904-0841OC","volume":"201","author":"DL Grieco","year":"2020","unstructured":"Grieco DL, Menga LS, Raggi V et al (2020) physiological comparison of high-flow nasal cannula and helmet noninvasive ventilation in acute hypoxemic respiratory failure. Am J Respir Crit Care Med 201:303\u2013312. https:\/\/doi.org\/10.1164\/rccm.201904-0841OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR11","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1001\/jama.2020.9524","volume":"324","author":"BL Ferreyro","year":"2020","unstructured":"Ferreyro BL, Angriman F, Munshi L et al (2020) Association of noninvasive oxygenation strategies with all-cause mortality in adults with acute hypoxemic respiratory failure. JAMA 324:57. https:\/\/doi.org\/10.1001\/jama.2020.9524","journal-title":"JAMA"},{"key":"6459_CR12","doi-asserted-by":"publisher","first-page":"2226","DOI":"10.1007\/s00134-020-06312-y","volume":"46","author":"B Rochwerg","year":"2020","unstructured":"Rochwerg B, Einav S, Chaudhuri D et al (2020) The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline. Intensive Care Med 46:2226\u20132237. https:\/\/doi.org\/10.1007\/s00134-020-06312-y","journal-title":"Intensive Care Med"},{"key":"6459_CR13","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02426-2016","author":"B Rochwerg","year":"2017","unstructured":"Rochwerg B, Brochard L, Elliott MW et al (2017) Official ERS\/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure. Eur Respir J. https:\/\/doi.org\/10.1183\/13993003.02426-2016","journal-title":"Eur Respir J"},{"key":"6459_CR14","doi-asserted-by":"publisher","first-page":"2002130","DOI":"10.1183\/13993003.02130-2020","volume":"56","author":"C Franco","year":"2020","unstructured":"Franco C, Facciolongo N, Tonelli R et al (2020) Feasibility and clinical impact of out-of-ICU noninvasive respiratory support in patients with COVID-19-related pneumonia. Eur Respir J 56:2002130. https:\/\/doi.org\/10.1183\/13993003.02130-2020","journal-title":"Eur Respir J"},{"key":"6459_CR15","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1183\/13993003.02130-2020","volume":"56","author":"C Franco","year":"2020","unstructured":"Franco C, Facciolongo N, Tonelli R et al (2020) Feasibility and clinical impact of out-of-ICU noninvasive respiratory support in patients with COVID-19-related pneumonia. Eur Respir J 56:122. https:\/\/doi.org\/10.1183\/13993003.02130-2020","journal-title":"Eur Respir J"},{"key":"6459_CR16","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-06294-x","author":"COVID-ICU Group on behalf of the REVA Network and the COVID-ICU Investigators","year":"2020","unstructured":"COVID-ICU Group on behalf of the REVA Network and the COVID-ICU Investigators (2020) Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study. Intensive Care Med. https:\/\/doi.org\/10.1007\/s00134-020-06294-x","journal-title":"Intensive Care Med"},{"key":"6459_CR17","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s13054-021-03469-w","volume":"25","author":"R Mellado-Artigas","year":"2021","unstructured":"Mellado-Artigas R, Ferreyro BL, Angriman F et al (2021) High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure. Crit Care 25:58. https:\/\/doi.org\/10.1186\/s13054-021-03469-w","journal-title":"Crit Care"},{"key":"6459_CR18","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1186\/s13054-021-03502-y","volume":"25","author":"A Coppadoro","year":"2021","unstructured":"Coppadoro A, Benini A, Fruscio R et al (2021) Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak. Crit Care 25:80. https:\/\/doi.org\/10.1186\/s13054-021-03502-y","journal-title":"Crit Care"},{"key":"6459_CR19","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.08622","author":"LS Menga","year":"2021","unstructured":"Menga LS, Cese LD, Bongiovanni F et al (2021) High failure rate of noninvasive oxygenation strategies in critically Ill subjects with acute hypoxemic respiratory failure due to COVID-19. Respir Care. https:\/\/doi.org\/10.4187\/respcare.08622","journal-title":"Respir Care"},{"key":"6459_CR20","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02524-2020","author":"C Brusasco","year":"2021","unstructured":"Brusasco C, Corradi F, Di Domenico A et al (2021) Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure. Eur Respir J. https:\/\/doi.org\/10.1183\/13993003.02524-2020","journal-title":"Eur Respir J"},{"key":"6459_CR21","doi-asserted-by":"publisher","first-page":"2168","DOI":"10.1007\/s00134-020-06292-z","volume":"46","author":"C-E Luyt","year":"2020","unstructured":"Luyt C-E, Bouadma L, Morris AC et al (2020) Pulmonary infections complicating ARDS. Intensive Care Med 46:2168\u20132183. https:\/\/doi.org\/10.1007\/s00134-020-06292-z","journal-title":"Intensive Care Med"},{"key":"6459_CR22","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1056\/NEJM199808133390703","volume":"339","author":"M Antonelli","year":"1998","unstructured":"Antonelli M, Conti G, Rocco M et al (1998) A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure. N Engl J Med 339:429\u2013435. https:\/\/doi.org\/10.1056\/NEJM199808133390703","journal-title":"N Engl J Med"},{"key":"6459_CR23","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1056\/NEJMra1208707","volume":"369","author":"AS Slutsky","year":"2013","unstructured":"Slutsky AS, Ranieri VM (2013) Ventilator-induced lung injury. N Engl J Med 369:2126\u20132136. https:\/\/doi.org\/10.1056\/NEJMra1208707","journal-title":"N Engl J Med"},{"key":"6459_CR24","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1007\/s00134-020-06307-9","volume":"46","author":"G Chanques","year":"2020","unstructured":"Chanques G, Constantin J-M, Devlin JW et al (2020) Analgesia and sedation in patients with ARDS. Intensive Care Med 46:2342\u20132356. https:\/\/doi.org\/10.1007\/s00134-020-06307-9","journal-title":"Intensive Care Med"},{"key":"6459_CR25","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1007\/s00134-020-06227-8","volume":"46","author":"W Alhazzani","year":"2020","unstructured":"Alhazzani W, Belley-Cote E, M\u00f8ller MH et al (2020) Neuromuscular blockade in patients with ARDS: a rapid practice guideline. Intensive Care Med 46:1977\u20131986. https:\/\/doi.org\/10.1007\/s00134-020-06227-8","journal-title":"Intensive Care Med"},{"key":"6459_CR26","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1001\/jama.293.5.589","volume":"293","author":"V Squadrone","year":"2005","unstructured":"Squadrone V, Coha M, Cerutti E et al (2005) Continuous positive airway pressure for treatment of postoperative hypoxemia: a randomized controlled trial. JAMA 293:589\u2013595. https:\/\/doi.org\/10.1001\/jama.293.5.589","journal-title":"JAMA"},{"key":"6459_CR27","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1164\/rccm.200401-042OC","volume":"170","author":"CSH Sassoon","year":"2004","unstructured":"Sassoon CSH, Zhu E, Caiozzo VJ (2004) Assist-control mechanical ventilation attenuates ventilator-induced diaphragmatic dysfunction. Am J Respir Crit Care Med 170:626\u2013632. https:\/\/doi.org\/10.1164\/rccm.200401-042OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR28","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1097\/00000542-197501000-00009","volume":"42","author":"J Qvist","year":"1975","unstructured":"Qvist J, Pontoppidan H, Wilson RS et al (1975) Hemodynamic responses to mechanical ventilation with PEEP: the effect of hypervolemia. Anesthesiology 42:45\u201355. https:\/\/doi.org\/10.1097\/00000542-197501000-00009","journal-title":"Anesthesiology"},{"key":"6459_CR29","first-page":"941","volume":"78","author":"X Repess\u00e9","year":"2012","unstructured":"Repess\u00e9 X, Charron C, Vieillard-Baron A (2012) Right ventricular failure in acute lung injury and acute respiratory distress syndrome. Minerva Anestesiol 78:941\u2013948","journal-title":"Minerva Anestesiol"},{"key":"6459_CR30","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1097\/00000542-200308000-00019","volume":"99","author":"H Wrigge","year":"2003","unstructured":"Wrigge H, Zinserling J, Neumann P et al (2003) Spontaneous breathing improves lung aeration in oleic acid-induced lung injury. Anesthesiology 99:376\u2013384. https:\/\/doi.org\/10.1097\/00000542-200308000-00019","journal-title":"Anesthesiology"},{"key":"6459_CR31","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1097\/01.ccm.0000163226.34868.0a","volume":"83","author":"S Ferrari","year":"1992","unstructured":"Ferrari S, Orlandi M, Avella M et al (1992) Effects of hydration on plasma concentrations of methotrexate in patients with osteosarcoma treated with high doses of methotrexate. Minerva Med 83:289\u2013293. https:\/\/doi.org\/10.1097\/01.ccm.0000163226.34868.0a","journal-title":"Minerva Med"},{"key":"6459_CR32","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1164\/ajrccm.164.1.2001078","volume":"164","author":"C Putensen","year":"2001","unstructured":"Putensen C, Zech S, Wrigge H et al (2001) Long-term effects of spontaneous breathing during ventilatory support in patients with acute lung injury. Am J Respir Crit Care Med 164:43\u201349. https:\/\/doi.org\/10.1164\/ajrccm.164.1.2001078","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR33","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1097\/MCC.0b013e328342726e","volume":"17","author":"JJ Marini","year":"2011","unstructured":"Marini JJ (2011) Spontaneously regulated vs. controlled ventilation of acute lung injury\/acute respiratory distress syndrome. Curr Opin Crit Care 17:24\u201329. https:\/\/doi.org\/10.1097\/MCC.0b013e328342726e","journal-title":"Curr Opin Crit Care"},{"key":"6459_CR34","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1097\/CCM.0b013e3182711972","volume":"41","author":"T Yoshida","year":"2013","unstructured":"Yoshida T, Uchiyama A, Matsuura N et al (2013) The comparison of spontaneous breathing and muscle paralysis in two different severities of experimental lung injury. Crit Care Med 41:536\u2013545. https:\/\/doi.org\/10.1097\/CCM.0b013e3182711972","journal-title":"Crit Care Med"},{"key":"6459_CR35","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1097\/MCC.0000000000000055","volume":"20","author":"A G\u00fcldner","year":"2014","unstructured":"G\u00fcldner A, Pelosi P, Gama de Abreu M (2014) Spontaneous breathing in mild and moderate versus severe acute respiratory distress syndrome. Curr Opin Crit Care 20:69\u201376. https:\/\/doi.org\/10.1097\/MCC.0000000000000055","journal-title":"Curr Opin Crit Care"},{"key":"6459_CR36","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1007\/s00134-020-05942-6","volume":"46","author":"E Spinelli","year":"2020","unstructured":"Spinelli E, Mauri T, Beitler JR et al (2020) Respiratory drive in the acute respiratory distress syndrome: pathophysiology, monitoring, and therapeutic interventions. Intensive Care Med 46:606\u2013618. https:\/\/doi.org\/10.1007\/s00134-020-05942-6","journal-title":"Intensive Care Med"},{"key":"6459_CR37","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1097\/CCM.0000000000001379","volume":"44","author":"G Carteaux","year":"2016","unstructured":"Carteaux G, Mill\u00e1n-Guilarte T, De Prost N et al (2016) Failure of noninvasive ventilation for de novo acute hypoxemic respiratory failure: role of tidal volume. Crit Care Med 44:282\u2013290. https:\/\/doi.org\/10.1097\/CCM.0000000000001379","journal-title":"Crit Care Med"},{"key":"6459_CR38","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1097\/CCM.0000000000002818","volume":"46","author":"J-P Frat","year":"2018","unstructured":"Frat J-P, Ragot S, Coudroy R et al (2018) Predictors of intubation in patients with acute hypoxemic respiratory failure treated with a noninvasive oxygenation strategy. Crit Care Med 46:208\u2013215. https:\/\/doi.org\/10.1097\/CCM.0000000000002818","journal-title":"Crit Care Med"},{"key":"6459_CR39","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1164\/rccm.201604-0748CP","volume":"195","author":"T Yoshida","year":"2017","unstructured":"Yoshida T, Fujino Y, Amato MBP, Kavanagh BP (2017) Fifty years of research in ARDS. Spontaneous breathing during mechanical ventilation. Risks, mechanisms, and management. Am J Respir Crit Care Med 195:985\u2013992. https:\/\/doi.org\/10.1164\/rccm.201604-0748CP","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR40","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1164\/rccm.201605-1081CP","volume":"195","author":"L Brochard","year":"2017","unstructured":"Brochard L, Slutsky A, Pesenti A (2017) Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med 195:438\u2013442. https:\/\/doi.org\/10.1164\/rccm.201605-1081CP","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR41","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1007\/BF00255628","volume":"15","author":"D Mascheroni","year":"1988","unstructured":"Mascheroni D, Kolobow T, Fumagalli R et al (1988) Acute respiratory failure following pharmacologically induced hyperventilation: an experimental animal study. Intensive Care Med 15:8\u201314. https:\/\/doi.org\/10.1007\/BF00255628","journal-title":"Intensive Care Med"},{"key":"6459_CR42","doi-asserted-by":"publisher","first-page":"1420","DOI":"10.1164\/rccm.201303-0539OC","volume":"188","author":"T Yoshida","year":"2013","unstructured":"Yoshida T, Torsani V, Gomes S et al (2013) Spontaneous effort causes occult pendelluft during mechanical ventilation. Am J Respir Crit Care Med 188:1420\u20131427. https:\/\/doi.org\/10.1164\/rccm.201303-0539OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR43","doi-asserted-by":"publisher","first-page":"e678","DOI":"10.1097\/CCM.0000000000001649","volume":"44","author":"T Yoshida","year":"2016","unstructured":"Yoshida T, Roldan R, Beraldo MA et al (2016) Spontaneous effort during mechanical ventilation: maximal injury with less positive end-expiratory pressure. Crit Care Med 44:e678\u2013e688. https:\/\/doi.org\/10.1097\/CCM.0000000000001649","journal-title":"Crit Care Med"},{"key":"6459_CR44","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1164\/rccm.201610-1972OC","volume":"196","author":"T Yoshida","year":"2017","unstructured":"Yoshida T, Nakahashi S, Nakamura MAM et al (2017) Volume-controlled ventilation does not prevent injurious inflation during spontaneous effort. Am J Respir Crit Care Med 196:590\u2013601. https:\/\/doi.org\/10.1164\/rccm.201610-1972OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR45","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.chest.2016.03.043","volume":"150","author":"M Bhattacharya","year":"2016","unstructured":"Bhattacharya M, Kallet RH, Ware LB, Matthay MA (2016) Negative-pressure pulmonary edema. Chest 150:927\u2013933. https:\/\/doi.org\/10.1016\/j.chest.2016.03.043","journal-title":"Chest"},{"key":"6459_CR46","doi-asserted-by":"publisher","first-page":"2314","DOI":"10.1007\/s00134-020-06288-9","volume":"46","author":"EC Goligher","year":"2020","unstructured":"Goligher EC, Jonkman AH, Dianti J et al (2020) Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort. Intensive Care Med 46:2314\u20132326. https:\/\/doi.org\/10.1007\/s00134-020-06288-9","journal-title":"Intensive Care Med"},{"key":"6459_CR47","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/S2213-2600(18)30366-7","volume":"7","author":"EC Goligher","year":"2019","unstructured":"Goligher EC, Brochard LJ, Reid WD et al (2019) Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure. Lancet Respir Med 7:90\u201398. https:\/\/doi.org\/10.1016\/S2213-2600(18)30366-7","journal-title":"Lancet Respir Med"},{"key":"6459_CR48","doi-asserted-by":"publisher","first-page":"1080","DOI":"10.1164\/rccm.201503-0620OC","volume":"192","author":"EC Goligher","year":"2015","unstructured":"Goligher EC, Fan E, Herridge MS et al (2015) Evolution of diaphragm thickness during mechanical ventilation. Impact of inspiratory effort. Am J Respir Crit Care Med 192:1080\u20131088. https:\/\/doi.org\/10.1164\/rccm.201503-0620OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR49","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.23736\/S0375-9393.19.13418-9","volume":"85","author":"DL Grieco","year":"2019","unstructured":"Grieco DL, Menga LS, Eleuteri D, Antonelli M (2019) Patient self-inflicted lung injury: implications for acute hypoxemic respiratory failure and ARDS patients on non-invasive support. Minerva Anestesiol 85:1014\u20131023. https:\/\/doi.org\/10.23736\/S0375-9393.19.13418-9","journal-title":"Minerva Anestesiol"},{"key":"6459_CR50","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1097\/MCC.0000000000000691","volume":"26","author":"T Yoshida","year":"2020","unstructured":"Yoshida T, Grieco DL, Brochard L, Fujino Y (2020) Patient self-inflicted lung injury and positive end-expiratory pressure for safe spontaneous breathing. Curr Opin Crit Care 26:59\u201365. https:\/\/doi.org\/10.1097\/MCC.0000000000000691","journal-title":"Curr Opin Crit Care"},{"key":"6459_CR51","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1164\/rccm.201803-0589OC","volume":"199","author":"O Roca","year":"2019","unstructured":"Roca O, Caralt B, Messika J et al (2019) An index combining respiratory rate and oxygenation to predict outcome of nasal high-flow therapy. Am J Respir Crit Care Med 199:1368\u20131376. https:\/\/doi.org\/10.1164\/rccm.201803-0589OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR52","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1007\/s00134-012-2475-6","volume":"38","author":"A Carrillo","year":"2012","unstructured":"Carrillo A, Gonzalez-Diaz G, Ferrer M et al (2012) Non-invasive ventilation in community-acquired pneumonia and severe acute respiratory failure. Intensive Care Med 38:458\u2013466. https:\/\/doi.org\/10.1007\/s00134-012-2475-6","journal-title":"Intensive Care Med"},{"key":"6459_CR53","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1007\/s00134-006-0324-1","volume":"32","author":"A Demoule","year":"2006","unstructured":"Demoule A, Girou E, Richard J-C et al (2006) Benefits and risks of success or failure of noninvasive ventilation. Intensive Care Med 32:1756\u20131765. https:\/\/doi.org\/10.1007\/s00134-006-0324-1","journal-title":"Intensive Care Med"},{"key":"6459_CR54","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1097\/CCM.0000000000001359","volume":"44","author":"KN Kangelaris","year":"2016","unstructured":"Kangelaris KN, Ware LB, Wang CY et al (2016) Timing of intubation and clinical outcomes in adults with acute respiratory distress syndrome. Crit Care Med 44:120\u2013129. https:\/\/doi.org\/10.1097\/CCM.0000000000001359","journal-title":"Crit Care Med"},{"key":"6459_CR55","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1172\/JCI106015","volume":"48","author":"S Olafsson","year":"1969","unstructured":"Olafsson S, Hyatt RE (1969) Ventilatory mechanics and expiratory flow limitation during exercise in normal subjects. J Clin Invest 48:564\u2013573. https:\/\/doi.org\/10.1172\/JCI106015","journal-title":"J Clin Invest"},{"key":"6459_CR56","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1113\/jphysiol.2006.126466","volume":"581","author":"JA Guenette","year":"2007","unstructured":"Guenette JA, Witt JD, McKenzie DC et al (2007) Respiratory mechanics during exercise in endurance-trained men and women. J Physiol 581:1309\u20131322. https:\/\/doi.org\/10.1113\/jphysiol.2006.126466","journal-title":"J Physiol"},{"key":"6459_CR57","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1164\/rccm.201912-2321LE","volume":"201","author":"DL Grieco","year":"2020","unstructured":"Grieco DL, Menga LS, Conti G et al (2020) Reply to Spinelli and Mauri: lung and diaphragm protection during noninvasive respiratory support. Am J Respir Crit Care Med 201:876\u2013878. https:\/\/doi.org\/10.1164\/rccm.201912-2321LE","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR58","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1164\/rccm.202003-0655CP","volume":"202","author":"EC Goligher","year":"2020","unstructured":"Goligher EC, Dres M, Patel BK et al (2020) Lung- and diaphragm-protective ventilation. Am J Respir Crit Care Med 202:950\u2013961. https:\/\/doi.org\/10.1164\/rccm.202003-0655CP","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR59","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1097\/CCM.0b013e31829e53dc","volume":"42","author":"R Vaschetto","year":"2014","unstructured":"Vaschetto R, Cammarota G, Colombo D et al (2014) Effects of propofol on patient-ventilator synchrony and interaction during pressure support ventilation and neurally adjusted ventilatory assist. Crit Care Med 42:74\u201382. https:\/\/doi.org\/10.1097\/CCM.0b013e31829e53dc","journal-title":"Crit Care Med"},{"key":"6459_CR60","doi-asserted-by":"publisher","first-page":"1326","DOI":"10.1097\/01.CCM.0000215513.63207.7F","volume":"34","author":"SS Carson","year":"2006","unstructured":"Carson SS, Kress JP, Rodgers JE et al (2006) A randomized trial of intermittent lorazepam versus propofol with daily interruption in mechanically ventilated patients. Crit Care Med 34:1326\u20131332. https:\/\/doi.org\/10.1097\/01.CCM.0000215513.63207.7F","journal-title":"Crit Care Med"},{"key":"6459_CR61","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1093\/bja\/aen094","volume":"100","author":"KTS Pattinson","year":"2008","unstructured":"Pattinson KTS (2008) Opioids and the control of respiration. Br J Anaesth 100:747\u2013758. https:\/\/doi.org\/10.1093\/bja\/aen094","journal-title":"Br J Anaesth"},{"key":"6459_CR62","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1017\/s0265021503000243","volume":"20","author":"T Bouillon","year":"2003","unstructured":"Bouillon T, Bruhn J, Roepcke H, Hoeft A (2003) Opioid-induced respiratory depression is associated with increased tidal volume variability. Eur J Anaesthesiol 20:127\u2013133. https:\/\/doi.org\/10.1017\/s0265021503000243","journal-title":"Eur J Anaesthesiol"},{"key":"6459_CR63","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1097\/00000542-199212000-00013","volume":"77","author":"JP Belleville","year":"1992","unstructured":"Belleville JP, Ward DS, Bloor BC, Maze M (1992) Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate. Anesthesiology 77:1125\u20131133. https:\/\/doi.org\/10.1097\/00000542-199212000-00013","journal-title":"Anesthesiology"},{"key":"6459_CR64","doi-asserted-by":"publisher","first-page":"e358","DOI":"10.1097\/CCM.0000000000003649","volume":"47","author":"T Kiss","year":"2019","unstructured":"Kiss T, Bluth T, Braune A et al (2019) Effects of positive end-expiratory pressure and spontaneous breathing activity on regional lung inflammation in experimental acute respiratory distress syndrome. Crit Care Med 47:e358\u2013e365. https:\/\/doi.org\/10.1097\/CCM.0000000000003649","journal-title":"Crit Care Med"},{"key":"6459_CR65","doi-asserted-by":"publisher","first-page":"1285","DOI":"10.1164\/rccm.201706-1244OC","volume":"197","author":"CCA Morais","year":"2018","unstructured":"Morais CCA, Koyama Y, Yoshida T et al (2018) High positive end-expiratory pressure renders spontaneous effort noninjurious. Am J Respir Crit Care Med 197:1285\u20131296. https:\/\/doi.org\/10.1164\/rccm.201706-1244OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR66","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1113\/jphysiol.1914.sp001684","volume":"49","author":"CL Evans","year":"1914","unstructured":"Evans CL, Hill AV (1914) The relation of length to tension development and heat production on contraction in muscle. J Physiol 49:10\u201316. https:\/\/doi.org\/10.1113\/jphysiol.1914.sp001684","journal-title":"J Physiol"},{"key":"6459_CR67","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1152\/japplphysiol.00753.2009","volume":"107","author":"A De Troyer","year":"2009","unstructured":"De Troyer A, Leduc D, Cappello M et al (2009) Mechanisms of the inspiratory action of the diaphragm during isolated contraction. J Appl Physiol 107:1736\u20131742. https:\/\/doi.org\/10.1152\/japplphysiol.00753.2009","journal-title":"J Appl Physiol"},{"key":"6459_CR68","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1001\/jama.2021.4682","volume":"325","author":"DL Grieco","year":"2021","unstructured":"Grieco DL, Menga LS, Cesarano M et al (2021) Effect of helmet noninvasive ventilation vs high-flow nasal oxygen on days free of respiratory support in patients with COVID-19 and moderate to severe hypoxemic respiratory failure: the HENIVOT randomized clinical trial. JAMA 325:1731\u20131743. https:\/\/doi.org\/10.1001\/jama.2021.4682","journal-title":"JAMA"},{"key":"6459_CR69","doi-asserted-by":"publisher","first-page":"2238","DOI":"10.1007\/s00134-020-06228-7","volume":"46","author":"J-D Ricard","year":"2020","unstructured":"Ricard J-D, Roca O, Lemiale V et al (2020) Use of nasal high flow oxygen during acute respiratory failure. Intensive Care Med 46:2238\u20132247. https:\/\/doi.org\/10.1007\/s00134-020-06228-7","journal-title":"Intensive Care Med"},{"key":"6459_CR70","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1007\/s00134-016-4277-8","volume":"42","author":"L Papazian","year":"2016","unstructured":"Papazian L, Corley A, Hess D et al (2016) Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review. Intensive Care Med 42:1336\u20131349. https:\/\/doi.org\/10.1007\/s00134-016-4277-8","journal-title":"Intensive Care Med"},{"key":"6459_CR71","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.4187\/respcare.01106","volume":"56","author":"RL Parke","year":"2011","unstructured":"Parke RL, Eccleston ML, McGuinness SP (2011) The effects of flow on airway pressure during nasal high-flow oxygen therapy. Respir Care 56:1151\u20131155. https:\/\/doi.org\/10.4187\/respcare.01106","journal-title":"Respir Care"},{"key":"6459_CR72","doi-asserted-by":"publisher","first-page":"886","DOI":"10.1093\/bja\/aep280","volume":"103","author":"R Parke","year":"2009","unstructured":"Parke R, McGuinness S, Eccleston M (2009) Nasal high-flow therapy delivers low level positive airway pressure. Br J Anaesth 103:886\u2013890. https:\/\/doi.org\/10.1093\/bja\/aep280","journal-title":"Br J Anaesth"},{"key":"6459_CR73","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.4187\/respcare.02358","volume":"58","author":"RL Parke","year":"2013","unstructured":"Parke RL, McGuinness SP (2013) Pressures delivered by nasal high flow oxygen during all phases of the respiratory cycle. Respir Care 58:1621\u20131624. https:\/\/doi.org\/10.4187\/respcare.02358","journal-title":"Respir Care"},{"key":"6459_CR74","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1093\/bja\/aer265","volume":"107","author":"Corley a., Caruana LR, Barnett a. G","year":"2011","unstructured":"Corley a., Caruana LR, Barnett a. G, et al (2011) Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients. Br J Anaesth 107:998\u20131004. https:\/\/doi.org\/10.1093\/bja\/aer265","journal-title":"Br J Anaesth"},{"key":"6459_CR75","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1186\/s13613-019-0591-y","volume":"9","author":"D Natalini","year":"2019","unstructured":"Natalini D, Grieco DL, Santantonio MT et al (2019) Physiological effects of high-flow oxygen in tracheostomized patients. Ann Intensive Care 9:114. https:\/\/doi.org\/10.1186\/s13613-019-0591-y","journal-title":"Ann Intensive Care"},{"key":"6459_CR76","doi-asserted-by":"publisher","first-page":"1525","DOI":"10.1152\/japplphysiol.00934.2014","volume":"118","author":"W M\u00f6ller","year":"2015","unstructured":"M\u00f6ller W, Celik G, Feng S et al (2015) Nasal high flow clears anatomical dead space in upper airway models. J Appl Physiol 118:1525\u20131532. https:\/\/doi.org\/10.1152\/japplphysiol.00934.2014","journal-title":"J Appl Physiol"},{"key":"6459_CR77","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1152\/japplphysiol.00584.2016","volume":"122","author":"W M\u00f6ller","year":"2017","unstructured":"M\u00f6ller W, Feng S, Domanski U et al (2017) Nasal high flow reduces dead space. J Appl Physiol 122:191\u2013197. https:\/\/doi.org\/10.1152\/japplphysiol.00584.2016","journal-title":"J Appl Physiol"},{"key":"6459_CR78","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.4187\/respcare.03814","volume":"60","author":"F Vargas","year":"2015","unstructured":"Vargas F, Saint-Leger M, Boyer A et al (2015) Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Respir Care 60:1369\u20131376. https:\/\/doi.org\/10.4187\/respcare.03814","journal-title":"Respir Care"},{"key":"6459_CR79","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1097\/CCM.0000000000002693","volume":"45","author":"M Delorme","year":"2017","unstructured":"Delorme M, Bouchard P-A, Simon M et al (2017) Effects of high-flow nasal cannula on the work of breathing in patients recovering from acute respiratory failure. Crit Care Med 45:1981\u20131988. https:\/\/doi.org\/10.1097\/CCM.0000000000002693","journal-title":"Crit Care Med"},{"key":"6459_CR80","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1164\/rccm.201605-0916OC","volume":"195","author":"T Mauri","year":"2017","unstructured":"Mauri T, Turrini C, Eronia N et al (2017) Physiologic effects of high-flow nasal cannula in acute hypoxemic respiratory failure. Am J Respir Crit Care Med 195:1207\u20131215. https:\/\/doi.org\/10.1164\/rccm.201605-0916OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR81","doi-asserted-by":"publisher","first-page":"1780","DOI":"10.1007\/s00134-011-2354-6","volume":"37","author":"B Sztrymf","year":"2011","unstructured":"Sztrymf B, Messika J, Bertrand F et al (2011) Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med 37:1780\u20131786. https:\/\/doi.org\/10.1007\/s00134-011-2354-6","journal-title":"Intensive Care Med"},{"key":"6459_CR82","doi-asserted-by":"publisher","first-page":"265","DOI":"10.4187\/respcare.00801","volume":"56","author":"RL Parke","year":"2011","unstructured":"Parke RL, McGuinness SP, Eccleston ML (2011) A preliminary randomized controlled trial to assess effectiveness of nasal high-flow oxygen in intensive care patients. Respir Care 56:265\u2013270. https:\/\/doi.org\/10.4187\/respcare.00801","journal-title":"Respir Care"},{"key":"6459_CR83","doi-asserted-by":"publisher","first-page":"938","DOI":"10.1111\/j.1365-2044.2008.05536.x","volume":"63","author":"MAB Sim","year":"2008","unstructured":"Sim MAB, Dean P, Kinsella J et al (2008) Performance of oxygen delivery devices when the breathing pattern of respiratory failure is simulated. Anaesthesia 63:938\u2013940. https:\/\/doi.org\/10.1111\/j.1365-2044.2008.05536.x","journal-title":"Anaesthesia"},{"key":"6459_CR84","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1007\/s00134-017-4890-1","volume":"43","author":"T Mauri","year":"2017","unstructured":"Mauri T, Alban L, Turrini C et al (2017) Optimum support by high-flow nasal cannula in acute hypoxemic respiratory failure: effects of increasing flow rates. Intensive Care Med 43:1453\u20131463. https:\/\/doi.org\/10.1007\/s00134-017-4890-1","journal-title":"Intensive Care Med"},{"key":"6459_CR85","doi-asserted-by":"publisher","first-page":"2185","DOI":"10.1056\/NEJMoa1503326","volume":"372","author":"J-P Frat","year":"2015","unstructured":"Frat J-P, Thille AW, Mercat A et al (2015) High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med 372:2185\u20132196. https:\/\/doi.org\/10.1056\/NEJMoa1503326","journal-title":"N Engl J Med"},{"key":"6459_CR86","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/S0140-6736(09)60496-7","volume":"374","author":"S Nava","year":"2009","unstructured":"Nava S, Hill N (2009) Non-invasive ventilation in acute respiratory failure. Lancet (London, England) 374:250\u2013259. https:\/\/doi.org\/10.1016\/S0140-6736(09)60496-7","journal-title":"Lancet (London, England)"},{"key":"6459_CR87","doi-asserted-by":"publisher","first-page":"2435","DOI":"10.1001\/jama.2016.6338","volume":"315","author":"BK Patel","year":"2016","unstructured":"Patel BK, Wolfe KS, Pohlman AS et al (2016) Effect of noninvasive ventilation delivered by helmet vs face mask on the rate of endotracheal intubation in patients with acute respiratory distress syndrome: a randomized clinical trial. JAMA 315:2435\u20132441. https:\/\/doi.org\/10.1001\/jama.2016.6338","journal-title":"JAMA"},{"key":"6459_CR88","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1164\/ajrccm\/143.3.469","volume":"143","author":"CS Sassoon","year":"1991","unstructured":"Sassoon CS, Light RW, Lodia R et al (1991) Pressure-time product during continuous positive airway pressure, pressure support ventilation, and T-piece during weaning from mechanical ventilation. Am Rev Respir Dis 143:469\u2013475. https:\/\/doi.org\/10.1164\/ajrccm\/143.3.469","journal-title":"Am Rev Respir Dis"},{"key":"6459_CR89","doi-asserted-by":"publisher","first-page":"1219","DOI":"10.1164\/ajrccm\/145.5.1219","volume":"145","author":"CS Sassoon","year":"1992","unstructured":"Sassoon CS, Lodia R, Rheeman CH et al (1992) Inspiratory muscle work of breathing during flow-by, demand-flow, and continuous-flow systems in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 145:1219\u20131222. https:\/\/doi.org\/10.1164\/ajrccm\/145.5.1219","journal-title":"Am Rev Respir Dis"},{"key":"6459_CR90","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.1007\/s00134-003-1931-8","volume":"29","author":"N Patroniti","year":"2003","unstructured":"Patroniti N, Foti G, Manfio A et al (2003) Head helmet versus face mask for non-invasive continuous positive airway pressure: a physiological study. Intensive Care Med 29:1680\u20131687. https:\/\/doi.org\/10.1007\/s00134-003-1931-8","journal-title":"Intensive Care Med"},{"key":"6459_CR91","first-page":"1144","volume":"81","author":"DL Grieco","year":"2015","unstructured":"Grieco DL, Biancone M, Maviglia R, Antonelli M (2015) A new strategy to deliver Helmet CPAP to critically ill patients: the possible role of ICU ventilators. Minerva Anestesiol 81:1144\u20131145","journal-title":"Minerva Anestesiol"},{"key":"6459_CR92","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1097\/CCM.0b013e31819b575f","volume":"37","author":"AT Fraticelli","year":"2009","unstructured":"Fraticelli AT, Lellouche F, L\u2019her E et al (2009) Physiological effects of different interfaces during noninvasive ventilation for acute respiratory failure. Crit Care Med 37:939\u2013945. https:\/\/doi.org\/10.1097\/CCM.0b013e31819b575f","journal-title":"Crit Care Med"},{"key":"6459_CR93","doi-asserted-by":"publisher","first-page":"617","DOI":"10.4187\/respcare.06635","volume":"64","author":"NR MacIntyre","year":"2019","unstructured":"MacIntyre NR (2019) Physiologic effects of noninvasive ventilation. Respir Care 64:617\u2013628. https:\/\/doi.org\/10.4187\/respcare.06635","journal-title":"Respir Care"},{"key":"6459_CR94","doi-asserted-by":"publisher","first-page":"1112","DOI":"10.1164\/rccm.200402-226OC","volume":"172","author":"E L\u2019Her","year":"2005","unstructured":"L\u2019Her E, Deye N, Lellouche F et al (2005) Physiologic effects of noninvasive ventilation during acute lung injury. Am J Respir Crit Care Med 172:1112\u20131118. https:\/\/doi.org\/10.1164\/rccm.200402-226OC","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR95","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1164\/ajrccm.163.2.9906116","volume":"163","author":"S Mehta","year":"2001","unstructured":"Mehta S, Hill NS (2001) Noninvasive ventilation. Am J Respir Crit Care Med 163:540\u2013577. https:\/\/doi.org\/10.1164\/ajrccm.163.2.9906116","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR96","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1097\/CCM.0000000000000819","volume":"43","author":"L Cabrini","year":"2015","unstructured":"Cabrini L, Landoni G, Oriani A et al (2015) Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and meta-analysis of randomized controlled trials. Crit Care Med 43:880\u2013888. https:\/\/doi.org\/10.1097\/CCM.0000000000000819","journal-title":"Crit Care Med"},{"key":"6459_CR97","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1001\/jama.1984.03350060051030","volume":"252","author":"JM Luce","year":"1984","unstructured":"Luce JM (1984) The cardiovascular effects of mechanical ventilation and positive end-expiratory pressure. JAMA 252:807\u2013811. https:\/\/doi.org\/10.1001\/jama.1984.03350060051030","journal-title":"JAMA"},{"key":"6459_CR98","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1186\/cc3877","volume":"9","author":"T Luecke","year":"2005","unstructured":"Luecke T, Pelosi P (2005) Clinical review: positive end-expiratory pressure and cardiac output. Crit Care 9:607\u2013621. https:\/\/doi.org\/10.1186\/cc3877","journal-title":"Crit Care"},{"key":"6459_CR99","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1164\/ajrccm.155.2.9032185","volume":"155","author":"F Lenique","year":"1997","unstructured":"Lenique F, Habis M, Lofaso F et al (1997) Ventilatory and hemodynamic effects of continuous positive airway pressure in left heart failure. Am J Respir Crit Care Med 155:500\u2013505. https:\/\/doi.org\/10.1164\/ajrccm.155.2.9032185","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR100","doi-asserted-by":"publisher","first-page":"2352","DOI":"10.1001\/jama.284.18.2352","volume":"284","author":"C Delclaux","year":"2000","unstructured":"Delclaux C, L\u2019Her E, Alberti C et al (2000) Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial. JAMA 284:2352\u20132360. https:\/\/doi.org\/10.1001\/jama.284.18.2352","journal-title":"JAMA"},{"key":"6459_CR101","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1007\/s00134-013-3032-7","volume":"39","author":"JCM Richard","year":"2013","unstructured":"Richard JCM, Lyazidi A, Akoumianaki E et al (2013) Potentially harmful effects of inspiratory synchronization during pressure preset ventilation. Intensive Care Med 39:2003\u20132010. https:\/\/doi.org\/10.1007\/s00134-013-3032-7","journal-title":"Intensive Care Med"},{"key":"6459_CR102","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1186\/s13613-017-0324-z","volume":"7","author":"N Rittayamai","year":"2017","unstructured":"Rittayamai N, Beloncle F, Goligher EC et al (2017) Effect of inspiratory synchronization during pressure-controlled ventilation on lung distension and inspiratory effort. Ann Intensive Care 7:100. https:\/\/doi.org\/10.1186\/s13613-017-0324-z","journal-title":"Ann Intensive Care"},{"key":"6459_CR103","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1007\/s00134-002-1208-7","volume":"28","author":"C Gregoretti","year":"2002","unstructured":"Gregoretti C, Confalonieri M, Navalesi P et al (2002) Evaluation of patient skin breakdown and comfort with a new face mask for non-invasive ventilation: a multi-center study. Intensive Care Med 28:278\u2013284. https:\/\/doi.org\/10.1007\/s00134-002-1208-7","journal-title":"Intensive Care Med"},{"key":"6459_CR104","first-page":"270","volume":"49","author":"AR Schwartz","year":"2004","unstructured":"Schwartz AR, Kacmarek RM, Hess DR (2004) Factors affecting oxygen delivery with bi-level positive airway pressure. Respir Care 49:270\u2013275","journal-title":"Respir Care"},{"key":"6459_CR105","first-page":"475","volume":"68","author":"M Scandroglio","year":"2002","unstructured":"Scandroglio M, Piccolo U, Mazzone E et al (2002) Use and nursing of the helmet in delivering non-invasive ventilation. Minerva Anestesiol 68:475\u2013480","journal-title":"Minerva Anestesiol"},{"key":"6459_CR106","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1097\/00003246-200203000-00019","volume":"30","author":"M Antonelli","year":"2002","unstructured":"Antonelli M, Conti G, Pelosi P et al (2002) New treatment of acute hypoxemic respiratory failure: noninvasive pressure support ventilation delivered by helmet\u2014a pilot controlled trial. Crit Care Med 30:602\u2013608. https:\/\/doi.org\/10.1097\/00003246-200203000-00019","journal-title":"Crit Care Med"},{"key":"6459_CR107","doi-asserted-by":"publisher","first-page":"2090","DOI":"10.1097\/01.ccm.0000142577.63316.c0","volume":"32","author":"P Taccone","year":"2004","unstructured":"Taccone P, Hess D, Caironi P, Bigatello LM (2004) Continuous positive airway pressure delivered with a \u201chelmet\u201d: effects on carbon dioxide rebreathing. Crit Care Med 32:2090\u20132096. https:\/\/doi.org\/10.1097\/01.ccm.0000142577.63316.c0","journal-title":"Crit Care Med"},{"key":"6459_CR108","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s00134-012-2686-x","volume":"39","author":"F Mojoli","year":"2013","unstructured":"Mojoli F, Iotti GA, Curr\u00f2 I et al (2013) An optimized set-up for helmet noninvasive ventilation improves pressure support delivery and patient-ventilator interaction. Intensive Care Med 39:38\u201344. https:\/\/doi.org\/10.1007\/s00134-012-2686-x","journal-title":"Intensive Care Med"},{"key":"6459_CR109","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1097\/CCM.0b013e31819fff93","volume":"37","author":"F Vargas","year":"2009","unstructured":"Vargas F, Thille A, Lyazidi A et al (2009) Helmet with specific settings versus facemask for noninvasive ventilation. Crit Care Med 37:1921\u20131928. https:\/\/doi.org\/10.1097\/CCM.0b013e31819fff93","journal-title":"Crit Care Med"},{"key":"6459_CR110","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1007\/s00134-003-1825-9","volume":"29","author":"D Chiumello","year":"2003","unstructured":"Chiumello D, Pelosi P, Carlesso E et al (2003) Noninvasive positive pressure ventilation delivered by helmet vs. standard face mask. Intensive Care Med 29:1671\u20131679. https:\/\/doi.org\/10.1007\/s00134-003-1825-9","journal-title":"Intensive Care Med"},{"key":"6459_CR111","doi-asserted-by":"publisher","first-page":"1454","DOI":"10.1007\/s00134-008-1109-5","volume":"34","author":"F Mojoli","year":"2008","unstructured":"Mojoli F, Iotti GA, Gerletti M et al (2008) Carbon dioxide rebreathing during non-invasive ventilation delivered by helmet: a bench study. Intensive Care Med 34:1454\u20131460. https:\/\/doi.org\/10.1007\/s00134-008-1109-5","journal-title":"Intensive Care Med"},{"key":"6459_CR112","doi-asserted-by":"publisher","first-page":"2338","DOI":"10.1007\/s00134-020-06167-3","volume":"46","author":"J Dianti","year":"2020","unstructured":"Dianti J, Bertoni M, Goligher EC (2020) Monitoring patient-ventilator interaction by an end-expiratory occlusion maneuver. Intensive Care Med 46:2338\u20132341. https:\/\/doi.org\/10.1007\/s00134-020-06167-3","journal-title":"Intensive Care Med"},{"key":"6459_CR113","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1164\/rccm.202006-2157CP","volume":"202","author":"MJ Tobin","year":"2020","unstructured":"Tobin MJ, Laghi F, Jubran A (2020) Why COVID-19 silent hypoxemia is baffling to physicians. Am J Respir Crit Care Med 202:356\u2013360. https:\/\/doi.org\/10.1164\/rccm.202006-2157CP","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR114","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1097\/01.CCM.0000251821.44259.F3","volume":"35","author":"M Antonelli","year":"2007","unstructured":"Antonelli M, Conti G, Esquinas A et al (2007) A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome. Crit Care Med 35:18\u201325. https:\/\/doi.org\/10.1097\/01.CCM.0000251821.44259.F3","journal-title":"Crit Care Med"},{"key":"6459_CR115","doi-asserted-by":"publisher","first-page":"1718","DOI":"10.1007\/s00134-001-1114-4","volume":"27","author":"M Antonelli","year":"2001","unstructured":"Antonelli M, Conti G, Moro ML et al (2001) Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multi-center study. Intensive Care Med 27:1718\u20131728. https:\/\/doi.org\/10.1007\/s00134-001-1114-4","journal-title":"Intensive Care Med"},{"key":"6459_CR116","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1164\/rccm.201804-0726CI","volume":"199","author":"E Akoumianaki","year":"2019","unstructured":"Akoumianaki E, Vaporidi K, Georgopoulos D (2019) The injurious effects of elevated or nonelevated respiratory rate during mechanical ventilation. Am J Respir Crit Care Med 199:149\u2013157. https:\/\/doi.org\/10.1164\/rccm.201804-0726CI","journal-title":"Am J Respir Crit Care Med"},{"key":"6459_CR117","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/s00540-008-0637-z","volume":"22","author":"Y Yoshida","year":"2008","unstructured":"Yoshida Y, Takeda S, Akada S et al (2008) Factors predicting successful noninvasive ventilation in acute lung injury. J Anesth 22:201\u2013206. https:\/\/doi.org\/10.1007\/s00540-008-0637-z","journal-title":"J Anesth"},{"key":"6459_CR118","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1007\/s00134-016-4601-3","volume":"43","author":"J Duan","year":"2017","unstructured":"Duan J, Han X, Bai L et al (2017) Assessment of heart rate, acidosis, consciousness, oxygenation, and respiratory rate to predict noninvasive ventilation failure in hypoxemic patients. Intensive Care Med 43:192\u2013199. https:\/\/doi.org\/10.1007\/s00134-016-4601-3","journal-title":"Intensive Care Med"},{"key":"6459_CR119","doi-asserted-by":"publisher","first-page":"17324","DOI":"10.1038\/s41598-019-54020-5","volume":"9","author":"A Cortegiani","year":"2019","unstructured":"Cortegiani A, Navalesi P, Accurso G et al (2019) Tidal volume estimation during helmet noninvasive ventilation: an experimental feasibility study. Sci Rep 9:17324. https:\/\/doi.org\/10.1038\/s41598-019-54020-5","journal-title":"Sci Rep"},{"key":"6459_CR120","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1007\/s00134-020-06033-2","volume":"46","author":"L Gattinoni","year":"2020","unstructured":"Gattinoni L, Chiumello D, Caironi P et al (2020) COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med 46:1099\u20131102. https:\/\/doi.org\/10.1007\/s00134-020-06033-2","journal-title":"Intensive Care Med"},{"key":"6459_CR121","doi-asserted-by":"publisher","first-page":"1595","DOI":"10.1164\/rccm.202004-1281LE","volume":"202","author":"M Teggia-Droghi","year":"2020","unstructured":"Teggia-Droghi M, Grassi A, Rezoagli E et al (2020) Comparison of two approaches to estimate driving pressure during assisted ventilation. Am J Respir Crit Care Med 202:1595\u20131598. https:\/\/doi.org\/10.1164\/rccm.202004-1281LE","journal-title":"Am J Respir Crit Care Med"},{"issue":"5 Pt 1","key":"6459_CR122","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1164\/ajrccm.160.5.9903015","volume":"160","author":"M Confalonieri","year":"1999","unstructured":"Confalonieri M, Potena A, Carbone G et al (1999) Acute respiratory failure in patients with severe community-acquired pneumonia. A prospective randomized evaluation of noninvasive ventilation. Am J Respir Crit Care Med 160(5 Pt 1):1585\u20131591. https:\/\/doi.org\/10.1164\/ajrccm.160.5.9903015","journal-title":"Am J Respir Crit Care Med."},{"issue":"3 Pt 1","key":"6459_CR123","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1164\/ajrccm.161.3.9808143","volume":"161","author":"TJ Martin","year":"2000","unstructured":"Martin TJ, Hovis JD, Costantino JP et al (2000) A randomized, prospective evaluation of noninvasive ventilation for acute respiratory failure. Am J Respir Crit Care Med 161(3 Pt 1):807\u2013813. https:\/\/doi.org\/10.1164\/ajrccm.161.3.9808143","journal-title":"Am J Respir Crit Care Med."},{"issue":"7","key":"6459_CR124","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1056\/NEJM200102153440703","volume":"344","author":"G Hilbert","year":"2001","unstructured":"Hilbert G, Gruson D, Vargas F et al (2001) Noninvasive ventilation in immunosuppressed patients with pulmonary infiltrates, fever, and acute respiratory failure. N Engl J Med 344(7):481\u2013487. https:\/\/doi.org\/10.1056\/NEJM200102153440703","journal-title":"N Engl J Med."},{"issue":"12","key":"6459_CR125","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1164\/rccm.200301-072OC","volume":"168","author":"M Ferrer","year":"2003","unstructured":"Ferrer M, Esquinas A, Leon M et al (2003) Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med 168(12):1438\u20131444. https:\/\/doi.org\/10.1164\/rccm.200301-072OC","journal-title":"Am J Respir Crit Care Med."},{"issue":"5","key":"6459_CR126","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1136\/emj.2004.019786","volume":"22","author":"M Gunduz","year":"2005","unstructured":"Gunduz M, Unlugenc H, Ozalevli M, Inanoglu K, Akman H (2005) A comparative study of continuous positive airway pressure (CPAP) and intermittent positive pressure ventilation (IPPV) in patients with flail chest. Emerg Med J 22(5):325\u2013329. https:\/\/doi.org\/10.1136\/emj.2004.019786","journal-title":"Emerg Med J."},{"issue":"1","key":"6459_CR127","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1378\/chest.09-1114","volume":"137","author":"G Hernandez","year":"2010","unstructured":"Hernandez G, Fernandez R, Lopez-Reina P et al (2010) Noninvasive ventilation reduces intubation in chest trauma-related hypoxemia: a randomized clinical trial. Chest 137(1):74\u201380. https:\/\/doi.org\/10.1378\/chest.09-1114","journal-title":"Chest."},{"issue":"4","key":"6459_CR128","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1038\/bmt.2011.160","volume":"47","author":"M Wermke","year":"2012","unstructured":"Wermke M, Schiemanck S, H\u00f6ffken G et al (2012) Respiratory failure in patients undergoing allogeneic hematopoietic SCT\u2014a randomized trial on early non-invasive ventilation based on standard care hematology wards. Bone Marrow Transplant 47(4):574\u2013580. https:\/\/doi.org\/10.1038\/bmt.2011.160","journal-title":"Bone Marrow Transplant."},{"issue":"2","key":"6459_CR129","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1097\/CCM.0b013e318232d75e","volume":"40","author":"Q Zhan","year":"2012","unstructured":"Zhan Q, Sun B, Liang L et al (2012) Early use of noninvasive positive pressure ventilation for acute lung injury: a multicenter randomized controlled trial. Crit Care Med 40(2):455\u2013460. https:\/\/doi.org\/10.1097\/CCM.0b013e318232d75e","journal-title":"Crit Care Med"},{"issue":"16","key":"6459_CR130","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.1001\/jama.2015.12402","volume":"314","author":"V Lemiale","year":"2015","unstructured":"Lemiale V, Mokart D, Resche-Rigon M et al (2015) Effect of noninvasive ventilation vs oxygen therapy on mortality among immunocompromised patients with acute respiratory failure: a randomized clinical trial. JAMA 314(16):1711\u20131719. https:\/\/doi.org\/10.1001\/jama.2015.12402","journal-title":"JAMA"},{"issue":"1","key":"6459_CR131","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1186\/s13054-019-2575-6","volume":"23","author":"H He","year":"2019","unstructured":"He H, Sun B, Liang L et al (2019) A multicenter RCT of noninvasive ventilation in pneumonia-induced early mild acute respiratory distress syndrome. Crit Care 23(1):300. https:\/\/doi.org\/10.1186\/s13054-019-2575-6","journal-title":"Crit Care"},{"issue":"Suppl 1","key":"6459_CR132","doi-asserted-by":"publisher","first-page":"A166","DOI":"10.1186\/2197-425X-3-S1-A166","volume":"3","author":"JR Azevedo","year":"2015","unstructured":"Azevedo JR, Montenegro WS, Leitao AL et al (2015) High flow nasal cannula oxygen (hfnc) versus non-invasive positive pressure ventilation (nippv) in acute hypoxemic respiratory failure. A pilot randomized controlled trial. Intensive Care Med Exp 3(Suppl 1):A166. https:\/\/doi.org\/10.1186\/2197-425X-3-S1-A166","journal-title":"Intensive Care Med Exp"},{"issue":"1","key":"6459_CR133","doi-asserted-by":"publisher","first-page":"73.e5","DOI":"10.1016\/j.annemergmed.2017.12.006","volume":"72","author":"P Doshi","year":"2018","unstructured":"Doshi P, Whittle JS, Bublewicz M et al (2018) High-velocity nasal insufflation in the treatment of respiratory failure: a randomized clinical trial. Ann Emerg Med 72(1):73.e5\u201383.e5. https:\/\/doi.org\/10.1016\/j.annemergmed.2017.12.006","journal-title":"Ann Emerg Med"},{"issue":"6","key":"6459_CR134","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1111\/1742-6723.12490","volume":"27","author":"N Bell","year":"2015","unstructured":"Bell N, Hutchinson CL, Green TC et al (2015) Randomised control trial of humidified high flow nasal cannulae versus standard oxygen in the emergency department. Emerg Med Australas 27(6):537\u2013541. https:\/\/doi.org\/10.1111\/1742-6723.12490","journal-title":"Emerg Med Australas"},{"issue":"3","key":"6459_CR135","doi-asserted-by":"publisher","first-page":"291","DOI":"10.4187\/respcare.04252","volume":"61","author":"PG Jones","year":"2016","unstructured":"Jones PG, Kamona S, Doran O, Sawtell F, Wilsher M (2016) Randomized controlled trial of humidified high-flow nasal oxygen for acute respiratory distress in the emergency department: the HOT-ER study. Respir Care 61(3):291\u2013299. https:\/\/doi.org\/10.4187\/respcare.04252","journal-title":"Respir Care."},{"issue":"20","key":"6459_CR136","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1001\/jama.2018.14282","volume":"320","author":"E Azoulay","year":"2018","unstructured":"Azoulay E, Lemiale V, Mokart D et al (2018) Effect of high-flow nasal oxygen vs standard oxygen on 28-day mortality in immunocompromised patients with acute respiratory failure: the high randomized clinical trial. JAMA 320(20):2099\u20132107. https:\/\/doi.org\/10.1001\/jama.2018.14282","journal-title":"JAMA"},{"issue":"1","key":"6459_CR137","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1378\/chest.09-2290","volume":"138","author":"R Cosentini","year":"2010","unstructured":"Cosentini R, Brambilla AM, Aliberti S et al (2010) Helmet continuous positive airway pressure vs oxygen therapy to improve oxygenation in community-acquired pneumonia: a randomized, controlled trial. Chest 138(1):114\u2013120. https:\/\/doi.org\/10.1378\/chest.09-2290","journal-title":"Chest"},{"issue":"10","key":"6459_CR138","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1007\/s00134-010-1934-1","volume":"36","author":"V Squadrone","year":"2010","unstructured":"Squadrone V, Massaia M, Bruno B et al (2010) Early CPAP prevents evolution of acute lung injury in patients with hematologic malignancy. Intensive Care Med 36(10):1666\u20131674. https:\/\/doi.org\/10.1007\/s00134-010-1934-1","journal-title":"Intensive Care Med"},{"issue":"7","key":"6459_CR139","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1007\/s00134-014-3325-5","volume":"40","author":"AM Brambilla","year":"2014","unstructured":"Brambilla AM, Aliberti S, Prina E et al (2014) Helmet CPAP vs. oxygen therapy in severe hypoxemic respiratory failure due to pneumonia. Intensive Care Med 40(7):942\u2013949. https:\/\/doi.org\/10.1007\/s00134-014-3325-5","journal-title":"Intensive Care Med"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-021-06459-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-021-06459-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-021-06459-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:36:46Z","timestamp":1744173406000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-021-06459-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,7]]},"references-count":139,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["6459"],"URL":"https:\/\/doi.org\/10.1007\/s00134-021-06459-2","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.740440886.793588139","asserted-by":"object"}]},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,7]]},"assertion":[{"value":"8 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"DLG has received payments for travel expenses by Maquet, Getinge and Air Liquide. MA has received personal fees by Maquet, and a research grant by Toray. TM received personal fees from Drager, Fisher and Paykel, BBraun and Mindray, outside of the submitted work. AWT has received personal fees (payments for lectures and travel expense coverage to attend scientific meetings) from Fisher & Paykel Healthcare, Maquet-Getinge, GE Healthcare, and Covidien. OR discloses a research grant from Hamilton Medical, he has received speaker fees from Hamilton Medical, Ambu and Aerogen Ltd, non-financial research support from Timpel and Masimo Corporation. JM reports personal fees from Faron, personal fees from Medtronic, personal fees from Janssen, and investigator-initiated grant from Covidien\/Medtronic and CIHR, all outside the submitted work (last 36\u00a0months). DLG and MA disclose a research grant by General Electric Healthcare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}