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BS is a consultant for and has received honoraria for giving lectures from Edwards Lifesciences Inc. (Irvine, CA, USA). BS is a consultant for and has received institutional restricted research grants and honoraria for giving lectures from Pulsion Medical Systems SE (Feldkirchen, Germany). BS has received institutional restricted research grants and honoraria for giving lectures from CNSystems Medizintechnik GmbH (Graz, Austria). BS is a consultant for and has received honoraria for giving lectures from Philips Medizin Systeme B\u00f6blingen GmbH (B\u00f6blingen, Germany). BS is a consultant for and has received honoraria for giving lectures from GE Healthcare (Chicago, IL, USA). BS is a consultant for Vygon (Aachen, Germany). BS is a consultant for and has received institutional restricted research grants from Retia Medical LLC. (Valhalla, NY, USA). BS was a consultant for and has received institutional restricted research grants from Tensys Medical Inc. (San Diego, CA, USA); FGZ has received grants for investigator-initiated trials from Bactiguard, Sweden, and Ionis Pharmaceuticals, USA, unrelated to the scope of this work. FGZ was the principal investigator of the BaSICS trial, which received logistics support from Baxter Hospitalar, Brazil; CI received educational grants from LaJolla Pharmaceuticals (LaJolla, Cal USA) and educational grants and speaker fees from Cytosorbents Europe (Berlin Germany). CI is Chief Scientific Officer and holds shares in Active Medical BV (Leiden, The Netherlands), a company that provides educational services, products and software related to clinical microcirculation using sublingual hand-held vital microscopes; AVB received a research grant from GSK. AVB received Fees from Air Liquide for being in an advisory board for conducting a clinical research; BL received grants from Novartis, Abiomed, Amomed, orion, Gettinge; MC performed consultancies for Edwards Lifesciences and Directed Systems;","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}