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AIRM declares receiving institutional support for CENTER-TBI from the European Union seventh Framework Program (grant 602150), and additional support from the Hannelore Kohl Stiftung (Germany), from OneMind (USA), from Integra LifeSciences Corporation (USA) and from NeuroTrauma Sciences (USA). Personal fees were received from PresuuraNeuro (DSMB) and NeuroTrauma Sciences, outside the scope of this work. DKM reports grants, consultancy fees, or payment for educational activity, from NeuroTrauma Sciences LLC, Lantmannen AB, GlaxoSmithKline Ltd, Calico LLC, Cortirio Ltd, all outside the submitted work. VFJN hold a grant from Roche Pharmaceuticals related to blood biomarkers and TBI. MO is consultant and member of Scientific Advisory Board of Neuroptics. MS is Editor-in-Chief of the Journal of Neurosurgical Anesthesiology. FST received lecture fees from INTEGRA and is Advisory Board Member from Neuroptics, all outside the submitted work. GC reports grants, personal fees as Speakers\u2019 Bureau Member and Advisory Board Member from Integra and Neuroptics, all outside the submitted work. The other authors declare no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}