{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T16:55:39Z","timestamp":1793033739365,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2023,5,13]],"date-time":"2023-05-13T00:00:00Z","timestamp":1683936000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81671198"],"award-info":[{"award-number":["81671198"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971699"],"award-info":[{"award-number":["81971699"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Clinical Research Plan of Shanghai Hospital Development Center","award":["16CR3011A"],"award-info":[{"award-number":["16CR3011A"]}]},{"name":"Shanghai Municipal Education Commission\u2014Gaofeng Clinical Medicine","award":["20152212"],"award-info":[{"award-number":["20152212"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1007\/s00134-023-07072-1","type":"journal-article","created":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T07:45:45Z","timestamp":1684136745000},"page":"633-644","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Acute traumatic coma awakening by right median nerve electrical stimulation: a randomised controlled trial"],"prefix":"10.1007","volume":"49","clinical-trial-number":[{"clinical-trial-number":"nct02645578","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Xiang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiemin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiarong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guodong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liansheng","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiancun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyou","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianghong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouhua","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaosheng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoliang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongdong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew I. R.","family":"Maas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajun","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiyao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junfeng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2090-8369","authenticated-orcid":false,"given":"Guoyi","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the ACES Participants","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiemin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiarong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deliang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ou","family":"Xueming","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guodong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xide","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yangyu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liansheng","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Zhonghua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiancun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanping","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiuyou","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuelei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianghong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuebing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shouhua","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaosheng","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingping","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueguang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanyu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoliang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongdong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,5,13]]},"reference":[{"issue":"10","key":"7072_CR1","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/S1474-4422(19)30232-7","volume":"18","author":"EW Steyerberg","year":"2019","unstructured":"Steyerberg EW et al (2019) Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. Lancet Neurol 18(10):923\u2013934","journal-title":"Lancet Neurol"},{"issue":"2","key":"7072_CR2","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1007\/s001340050037","volume":"26","author":"GM Teasdale","year":"2000","unstructured":"Teasdale GM, Murray L (2000) Revisiting the Glasgow Coma Scale and Coma Score. Intensive Care Med 26(2):153\u2013154","journal-title":"Intensive Care Med"},{"issue":"8","key":"7072_CR3","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1016\/S1474-4422(20)30182-4","volume":"19","author":"G Gao","year":"2020","unstructured":"Gao G et al (2020) Clinical characteristics and outcomes in patients with traumatic brain injury in China: a prospective, multicentre, longitudinal, observational study. Lancet Neurol 19(8):670\u2013677","journal-title":"Lancet Neurol"},{"issue":"8","key":"7072_CR4","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1001\/jamaneurol.2021.2043","volume":"78","author":"MA McCrea","year":"2021","unstructured":"McCrea MA et al (2021) Functional outcomes over the first year after moderate to severe traumatic brain injury in the prospective, Longitudinal TRACK-TBI study. JAMA Neurol 78(8):982\u2013992","journal-title":"JAMA Neurol"},{"issue":"1","key":"7072_CR5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.3233\/NRE-161387","volume":"40","author":"Q Tang","year":"2017","unstructured":"Tang Q et al (2017) Prevalence of persistent vegetative state in patients with severe traumatic brain injury and its trend during the past four decades: a meta-analysis. NeuroRehabilitation 40(1):23\u201331","journal-title":"NeuroRehabilitation"},{"issue":"10","key":"7072_CR6","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1007\/s00134-021-06484-1","volume":"47","author":"E van Veen","year":"2021","unstructured":"van Veen E et al (2021) Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study. Intensive Care Med 47(10):1115\u20131129","journal-title":"Intensive Care Med"},{"issue":"9","key":"7072_CR7","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1056\/NEJMoa1102609","volume":"366","author":"JT Giacino","year":"2012","unstructured":"Giacino JT et al (2012) Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med 366(9):819\u2013826","journal-title":"N Engl J Med"},{"issue":"Suppl 1","key":"7072_CR8","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/s12028-021-01227-y","volume":"35","author":"BL Edlow","year":"2021","unstructured":"Edlow BL et al (2021) Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions. Neurocrit Care 35(Suppl 1):68\u201385","journal-title":"Neurocrit Care"},{"issue":"4","key":"7072_CR9","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1080\/026990599121638","volume":"13","author":"JB Cooper","year":"1999","unstructured":"Cooper JB et al (1999) Right median nerve electrical stimulation to hasten awakening from coma. Brain Inj 13(4):261\u2013267","journal-title":"Brain Inj"},{"key":"7072_CR10","first-page":"11","volume":"87","author":"JT Liu","year":"2003","unstructured":"Liu JT et al (2003) Regaining consciousness for prolonged comatose patients with right median nerve stimulation. Acta Neurochir Suppl 87:11\u201314","journal-title":"Acta Neurochir Suppl"},{"issue":"10","key":"7072_CR11","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1080\/02699050110065709","volume":"15","author":"CV Peri","year":"2001","unstructured":"Peri CV et al (2001) Pilot study of electrical stimulation on median nerve in comatose severe brain injured patients: 3-month outcome. Brain Inj 15(10):903\u2013910","journal-title":"Brain Inj"},{"issue":"20","key":"7072_CR12","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.1089\/neu.2014.3768","volume":"32","author":"J Lei","year":"2015","unstructured":"Lei J et al (2015) Right median nerve electrical stimulation for acute traumatic coma patients. J Neurotrauma 32(20):1584\u20131589","journal-title":"J Neurotrauma"},{"key":"7072_CR13","unstructured":"Guoyi Gao EC, Jiang J (2011) Right median nerve stimulation in posttraumatic coma. In: Abstracts from the 10th international neurotrauma symposium (INTS) April 27\u201330, 2011. 2011, Journal of Neurotrauma: Shanghai, China"},{"key":"7072_CR14","unstructured":"Gao G (2022) Scans: a story of Shanghai coma afferent nerve stimulation on traumatic coma. In: Abstracts from The 15th International Neurotrauma Symposium. 2022, Journal of Neurotrauma: Berlin, Germany"},{"issue":"1","key":"7072_CR15","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1186\/s13063-017-2045-x","volume":"18","author":"X Wu","year":"2017","unstructured":"Wu X et al (2017) Right median nerve electrical stimulation for acute traumatic coma (the Asia Coma Electrical Stimulation trial): study protocol for a randomised controlled trial. Trials 18(1):311","journal-title":"Trials"},{"issue":"8","key":"7072_CR16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050165","volume":"5","author":"EW Steyerberg","year":"2008","unstructured":"Steyerberg EW et al (2008) Predicting outcome after traumatic brain injury: development and international validation of prognostic scores based on admission characteristics. PLoS Med 5(8):e165","journal-title":"PLoS Med"},{"issue":"1","key":"7072_CR17","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1227\/NEU.0000000000001432","volume":"80","author":"N Carney","year":"2017","unstructured":"Carney N et al (2017) Guidelines for the management of severe traumatic brain injury, fourth edition. Neurosurgery 80(1):6\u201315","journal-title":"Neurosurgery"},{"issue":"10","key":"7072_CR18","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1212\/WNL.0000000000005926","volume":"91","author":"JT Giacino","year":"2018","unstructured":"Giacino JT et al (2018) Practice guideline update recommendations summary: Disorders of consciousness: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology; the American Congress of Rehabilitation Medicine; and the National Institute on Disability, Independent Living, and Rehabilitation Research. Neurology 91(10):450\u2013460","journal-title":"Neurology"},{"issue":"5","key":"7072_CR19","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1111\/ene.14151","volume":"27","author":"D Kondziella","year":"2020","unstructured":"Kondziella D et al (2020) European Academy of Neurology guideline on the diagnosis of coma and other disorders of consciousness. Eur J Neurol 27(5):741\u2013756","journal-title":"Eur J Neurol"},{"issue":"6","key":"7072_CR20","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1016\/S1474-4422(19)30031-6","volume":"18","author":"A Thibaut","year":"2019","unstructured":"Thibaut A et al (2019) Therapeutic interventions in patients with prolonged disorders of consciousness. Lancet Neurol 18(6):600\u2013614","journal-title":"Lancet Neurol"},{"issue":"26","key":"7072_CR21","first-page":"4167","volume":"20","author":"O Gosseries","year":"2014","unstructured":"Gosseries O et al (2014) Amantadine, apomorphine and zolpidem in the treatment of disorders of consciousness. Curr Pharm Des 20(26):4167\u20134184","journal-title":"Curr Pharm Des"},{"issue":"1","key":"7072_CR22","doi-asserted-by":"publisher","first-page":"4401","DOI":"10.1038\/s41598-021-83873-y","volume":"11","author":"M Raguz","year":"2021","unstructured":"Raguz M et al (2021) Structural changes in brains of patients with disorders of consciousness treated with deep brain stimulation. Sci Rep 11(1):4401","journal-title":"Sci Rep"},{"issue":"4","key":"7072_CR23","doi-asserted-by":"publisher","first-page":"428","DOI":"10.3390\/brainsci12040428","volume":"12","author":"JA Cain","year":"2022","unstructured":"Cain JA et al (2022) Ultrasonic deep brain neuromodulation in acute disorders of consciousness: a proof-of-concept. Brain Sci 12(4):428","journal-title":"Brain Sci"},{"issue":"4","key":"7072_CR24","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1002\/stem.2538","volume":"35","author":"CS Cox Jr","year":"2017","unstructured":"Cox CS Jr et al (2017) Treatment of severe adult traumatic brain injury using bone marrow mononuclear cells. Stem Cells 35(4):1065\u20131079","journal-title":"Stem Cells"},{"issue":"2","key":"7072_CR25","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1055\/s-0033-1348960","volume":"33","author":"JT Giacino","year":"2013","unstructured":"Giacino JT, Katz DI, Whyte J (2013) Neurorehabilitation in disorders of consciousness. Semin Neurol 33(2):142\u2013156","journal-title":"Semin Neurol"},{"issue":"10","key":"7072_CR26","doi-asserted-by":"publisher","first-page":"1908","DOI":"10.1016\/j.apmr.2012.11.052","volume":"94","author":"RT Seel","year":"2013","unstructured":"Seel RT et al (2013) Specialized early treatment for persons with disorders of consciousness: program components and outcomes. Arch Phys Med Rehabil 94(10):1908\u20131923","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"7072_CR27","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1016\/j.brs.2016.12.004","volume":"10","author":"YT Yu","year":"2017","unstructured":"Yu YT et al (2017) Transcutaneous auricular vagus nerve stimulation in disorders of consciousness monitored by fMRI: the first case report. Brain Stimul 10(2):328\u2013330","journal-title":"Brain Stimul"},{"issue":"1","key":"7072_CR28","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.jelekin.2014.10.009","volume":"25","author":"CC Chen","year":"2015","unstructured":"Chen CC et al (2015) Neuromuscular electrical stimulation of the median nerve facilitates low motor cortex excitability in patients with spinocerebellar ataxia. J Electromyogr Kinesiol 25(1):143\u2013150","journal-title":"J Electromyogr Kinesiol"},{"issue":"1","key":"7072_CR29","doi-asserted-by":"publisher","first-page":"17720","DOI":"10.1038\/s41598-021-96660-6","volume":"11","author":"C Reis","year":"2021","unstructured":"Reis C et al (2021) Essential tremor amplitude modulation by median nerve stimulation. Sci Rep 11(1):17720","journal-title":"Sci Rep"},{"key":"7072_CR30","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1016\/j.neurom.2021.10.005","volume":"25","author":"A Maharjan","year":"2022","unstructured":"Maharjan A et al (2022) Investigation of the optimal parameters of median nerve stimulation, using a variety of stimulation methods, and its effects on heart rate variability: a systematic review. Neuromodulation 25:1268\u20131279","journal-title":"Neuromodulation"},{"issue":"3\u20134","key":"7072_CR31","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1080\/09602010443000317","volume":"15","author":"EB Cooper","year":"2005","unstructured":"Cooper EB, Scherder EJ, Cooper JB (2005) Electrical treatment of reduced consciousness: experience with coma and Alzheimer\u2019s disease. Neuropsychol Rehabil 15(3\u20134):389\u2013405","journal-title":"Neuropsychol Rehabil"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-023-07072-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-023-07072-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-023-07072-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T05:07:01Z","timestamp":1687496821000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-023-07072-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,13]]},"references-count":31,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["7072"],"URL":"https:\/\/doi.org\/10.1007\/s00134-023-07072-1","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,13]]},"assertion":[{"value":"22 November 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 May 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The ACES trial has been conducted in accordance with all relevant laws of the People\u2019s Republic of China, including but not limited to, the relevant privacy and data protection laws and regulations (the \u201cPrivacy Law\u201d), the relevant laws and regulations on the use of human materials, and all relevant guidance relating to clinical studies from time to time in force including, but not limited to, the ICH Harmonised Tripartite Guideline for Good Clinical Practice (CPMP\/ICH\/135\/95) (\u201cICH GCP\u201d) and the World Medical Association Declaration of Helsinki entitled \u201cEthical Principles for Medical Research Involving Human Subjects\u201d. Ethical approval was obtained for all recruiting sites.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}}]}}