{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T18:18:46Z","timestamp":1764181126495,"version":"3.46.0"},"reference-count":4,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s00134-025-08102-w","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T08:17:57Z","timestamp":1757492277000},"page":"2172-2173","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit"],"prefix":"10.1007","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6462-1343","authenticated-orcid":false,"given":"Hira","family":"Khalid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"8102_CR1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-025-08002-z","author":"A MekontsoDessap","year":"2025","unstructured":"MekontsoDessap A, Ricard JD, Contou D, Desnos C, Decav\u00e8le M, Sonneville R, Vivier E, Terzi N, Callahan JC, Jochmans S, Leon R, Carreira S, Nseir S, Chemouni F, Castelain V, Paul M, Benoist JF, Audureau E, Razazi K, CARMAS and the REVA research networks, on behalf of the DEMEL Investigators (2025) Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL). Intensive Care Med. https:\/\/doi.org\/10.1007\/s00134-025-08002-z","journal-title":"Intensive Care Med"},{"issue":"3","key":"8102_CR2","doi-asserted-by":"publisher","first-page":"434","DOI":"10.2174\/1570159X14666161228122115","volume":"15","author":"S Tordjman","year":"2017","unstructured":"Tordjman S, Chokron S, Delorme R, Charrier A, Bellissant E, Jaafari N, Fougerou C (2017) Melatonin: pharmacology, functions and therapeutic benefits. Curr Neuropharmacol 15(3):434\u2013443. https:\/\/doi.org\/10.2174\/1570159X14666161228122115","journal-title":"Curr Neuropharmacol"},{"issue":"7","key":"8102_CR3","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1097\/CCM.0000000000003132","volume":"46","author":"M Nishikimi","year":"2018","unstructured":"Nishikimi M, Numaguchi A, Takahashi K, Miyagawa Y, Matsui K, Higashi M, Makishi G, Matsui S, Matsuda N (2018) Effect of administration of ramelteon, a melatonin receptor agonist, on the duration of stay in the ICU: a single-center randomized placebo-controlled trial. Crit Care Med 46(7):1099\u20131105. https:\/\/doi.org\/10.1097\/CCM.0000000000003132","journal-title":"Crit Care Med"},{"issue":"1","key":"8102_CR4","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s13613-018-0408-4","volume":"8","author":"MT Altman","year":"2018","unstructured":"Altman MT, Knauert MP, Murphy TE, Ahasic AM, Chauhan Z, Pisani MA (2018) Association of intensive care unit delirium with sleep disturbance and functional disability after critical illness: an observational cohort study. Ann Intensive Care 8(1):63. https:\/\/doi.org\/10.1186\/s13613-018-0408-4","journal-title":"Ann Intensive Care"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-025-08102-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-025-08102-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-025-08102-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T18:14:17Z","timestamp":1764180857000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-025-08102-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,10]]},"references-count":4,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["8102"],"URL":"https:\/\/doi.org\/10.1007\/s00134-025-08102-w","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"type":"print","value":"0342-4642"},{"type":"electronic","value":"1432-1238"}],"subject":[],"published":{"date-parts":[[2025,9,10]]},"assertion":[{"value":"27 August 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"We, the undersigned authors, declare that we have no conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}}]}}