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The authors declare no further conflicts of interest. English language editing was performed by Editage (\n                      \n                      ).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The Medical Ethics Committee of the Maastricht University Medical Centre\u2009+\u2009confirmed that the Medical Research Involving Human Subjects Act (WMO) did not apply to our observational study and that official approval for this study by the committee was not required (17-4-025, dated 12th April 2017). The committee approved the anonymised analysis of blood samples during the treatment course.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All the authors approved the manuscript for submission.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}