{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:02:34Z","timestamp":1780934554802,"version":"3.54.1"},"reference-count":7,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2026,5]]},"DOI":"10.1007\/s00134-025-08276-3","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T10:21:04Z","timestamp":1767781264000},"page":"1132-1134","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adsorption of caspofungin by polyacrylonitrile membranes during continuous kidney replacement therapy"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2990-7947","authenticated-orcid":false,"given":"Laura","family":"Zeppilli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4897-1602","authenticated-orcid":false,"given":"Santo","family":"Morabito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0834-5586","authenticated-orcid":false,"given":"Pasquale","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-9462","authenticated-orcid":false,"given":"Valentina","family":"Pistolesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the AKI and Extracorporeal Therapies in Critical Area project group of the Italian Society of Nephrology","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"8276_CR1","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s40262-024-01461-5","volume":"64","author":"M Albanell-Fern\u00e1ndez","year":"2025","unstructured":"Albanell-Fern\u00e1ndez M (2025) Echinocandins pharmacokinetics: a comprehensive review of micafungin, caspofungin, anidulafungin, and rezafungin population pharmacokinetic models and dose optimization in special populations. Clin Pharmacokinet 64:27\u201352. https:\/\/doi.org\/10.1007\/s40262-024-01461-5","journal-title":"Clin Pharmacokinet"},{"key":"8276_CR2","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1007\/s00134-025-07793-5","volume":"51","author":"JA Roberts","year":"2025","unstructured":"Roberts JA, Sime FB, Lipman J, Hern\u00e1ndez-Mitre MP, Baptista JP, Br\u00fcggemann RJ, Darvall J, De Waele JJ, Dimopoulos G, Lefrant JY, Mat Nor MB, Rello J, Seoane L, Slavin MA, Valkonen M, Venditti M, Ceccarelli G, Wong WT, Zeitlinger M, Roger C (2025) Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units-the SAFE-ICU study. Intensive Care Med 51:302\u2013317. https:\/\/doi.org\/10.1007\/s00134-025-07793-5","journal-title":"Intensive Care Med"},{"key":"8276_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2020.01.007","volume":"40","author":"FJ Baud","year":"2021","unstructured":"Baud FJ, Jullien V, Secr\u00e9tan PH, Houz\u00e9 P, Lamhaut L (2021) Are we correctly treating invasive candidiasis under continuous renal replacement therapy with echinocandins? Preliminary in vitro assessment. Anaesth Crit Care Pain Med 40:100640. https:\/\/doi.org\/10.1016\/j.accpm.2020.01.007","journal-title":"Anaesth Crit Care Pain Med"},{"key":"8276_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2023.107007","volume":"62","author":"FJ Baud","year":"2023","unstructured":"Baud FJ, Jullien V, Desnos-Ollivier M, Lamhaut L, Lortholary O (2023) Caspofungin sequestration in a polyacrylonitrile-derived filter: increasing the dose does not mitigate sequestration. Int J Antimicrob Agents 62:107007. https:\/\/doi.org\/10.1016\/j.ijantimicag.2023.107007","journal-title":"Int J Antimicrob Agents"},{"key":"8276_CR5","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/j.therap.2020.12.013","volume":"76","author":"JH Raphalen","year":"2021","unstructured":"Raphalen JH, Mar\u00e7ais A, Parize P, Pilmis B, Lillo-Lelouet A, Lamhaut L, Baud FJ (2021) Is caspofungin efficient to treat invasive candidiasis requiring continuous veno-venous hemofiltration? A case report. Therapie 76:512\u2013515. https:\/\/doi.org\/10.1016\/j.therap.2020.12.013","journal-title":"Therapie"},{"key":"8276_CR6","doi-asserted-by":"publisher","first-page":"1997","DOI":"10.1007\/s40121-025-01191-6","volume":"14","author":"R Arrestier","year":"2025","unstructured":"Arrestier R, Pressiat C, Bouabdallah L, Masi P, Mongardon N, Hulin A, MekontsoDessap A, Razazi K (2025) Impact of continuous renal replacement therapy with polyacrylonitrile-derived filter on caspofungin concentration: a retrospective study. Infect Dis Ther 14:1997\u20132006. https:\/\/doi.org\/10.1007\/s40121-025-01191-6","journal-title":"Infect Dis Ther"},{"key":"8276_CR7","doi-asserted-by":"publisher","first-page":"dkaf390","DOI":"10.1093\/jac\/dkaf390","volume":"22","author":"A H\u00e9rault","year":"2025","unstructured":"H\u00e9rault A, Nicolas J, Demailly Z, Tamion F, Vodovar D (2025) Retrospective analysis of pharmacological therapeutic monitoring of caspofungin in patients undergoing continuous renal replacement therapy using polyacrylonitrile membranes. J Antimicrob Chemother 22:dkaf390. https:\/\/doi.org\/10.1093\/jac\/dkaf390","journal-title":"J Antimicrob Chemother"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-025-08276-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-025-08276-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-025-08276-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T15:41:16Z","timestamp":1780933276000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-025-08276-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,7]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["8276"],"URL":"https:\/\/doi.org\/10.1007\/s00134-025-08276-3","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,7]]},"assertion":[{"value":"7 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 December 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}