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Dr. Pottecher reports receiving consulting fees from Masimo, LFB Biomedicaments, and Octapharma. Dr. Boyd reports receiving an in-kind donation of cerebral oximeters from Edwards Life Sciences for his research program. Dr English and Dr Docherty declare academic grants. All authors have completed and submitted the ICMJE disclosure form. No potential conflicts of interest relevant to this article were reported for the other authors.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The HEMOTION trial protocol was approved by the research ethics board at the Centre Hospitalier Universitaire de\u00a0Qu\u00e9bec-Universit\u00e9 Laval and at all participating centers. A priori or deferred informed consent was obtained from surrogate decision makers for each participant. Consent was later obtained from patients if they regained capacity.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}