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Dr. Schaller holds small amounts of stock in Alphabet Inc., Ascendis Pharma Inc., Bayer AG, and Siemens AG; these holdings have not influenced any decisions regarding his research or this study. SJS reports that he is an associate editor of ICM and that he had not participated in reviewing or the decision-making process for the current manuscript. MS receives grant support from the Medical Research Council, Wellcome Trust, NIHR, ESICM and the Rosetrees Trust, and has recently participated on advisory boards for Aptarion, Bayer, deePull, Radiometer, Roche, Sanofi, Matisse, Vantive and Volition. He is a council member of the International Sepsis Forum and the Sepsis Topic Advisor for NICE.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}