{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:08:21Z","timestamp":1792782501635,"version":"4.5.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Universit\u00e0 Cattolica del Sacro Cuore","id":[{"id":"https:\/\/ror.org\/03h7r5v07","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1007\/s00134-026-08562-8","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T16:22:14Z","timestamp":1787156534000},"page":"2071-2084","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Respiratory mechanics modifies the impact of ventilator settings on clinical outcome in patients with acute brain injury"],"prefix":"10.1007","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4557-6308","authenticated-orcid":false,"given":"Domenico Luca","family":"Grieco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Stronati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Robba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Ros\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida G.","family":"Iavarone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Rezoagli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Bongiovanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio M.","family":"Dell\u2019Anna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Cardu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Graziano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Galimberti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anselmo","family":"Caricato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"Patroniti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio Silvio","family":"Taccone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Citerio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"8562_CR1","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","volume":"342","author":"ARDS Network","year":"2000","unstructured":"Acute Respiratory Distress Syndrome Network ARDS, Brower RG, Matthay MA et al (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301\u20131308. https:\/\/doi.org\/10.1056\/NEJM200005043421801","journal-title":"N Engl J Med"},{"key":"8562_CR2","doi-asserted-by":"publisher","first-page":"2126","DOI":"10.1056\/NEJMra1208707","volume":"369","author":"AS Slutsky","year":"2013","unstructured":"Slutsky AS, Ranieri VM (2013) Ventilator-induced lung injury. N Engl J Med 369:2126\u20132136. https:\/\/doi.org\/10.1056\/NEJMra1208707","journal-title":"N Engl J Med"},{"key":"8562_CR3","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1007\/s00134-024-07366-y","volume":"50","author":"O Roca","year":"2024","unstructured":"Roca O, Telias I, Grieco DL (2024) Bedside-available strategies to minimise P-SILI and VILI during ARDS. Intensive Care Med 50:597\u2013601. https:\/\/doi.org\/10.1007\/s00134-024-07366-y","journal-title":"Intensive Care Med"},{"key":"8562_CR4","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/S2213-2600(16)00057-6","volume":"4","author":"AS Neto","year":"2016","unstructured":"Neto AS, Hemmes SNT, Barbas CSV et al (2016) Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respir Med 4:272\u2013280. https:\/\/doi.org\/10.1016\/S2213-2600(16)00057-6","journal-title":"Lancet Respir Med"},{"key":"8562_CR5","doi-asserted-by":"publisher","first-page":"932","DOI":"10.1164\/rccm.202409-1813SO","volume":"211","author":"D Georgopoulos","year":"2025","unstructured":"Georgopoulos D, Taran S, Bolaki M, Akoumianaki E (2025) Mechanical ventilation in patients with acute brain injuries: a pathophysiology-based approach. Am J Respir Crit Care Med 211:932\u2013945. https:\/\/doi.org\/10.1164\/rccm.202409-1813SO","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR6","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1164\/rccm.202402-0402LE","volume":"209","author":"S Wahlster","year":"2024","unstructured":"Wahlster S, Sharma M, Taran S et al (2024) Associations between driving pressure and clinical outcomes in acute brain injury: a subanalysis of ENIO. Am J Respir Crit Care Med 209:1400\u20131404. https:\/\/doi.org\/10.1164\/rccm.202402-0402LE","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR7","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1001\/jama.2012.13730","volume":"308","author":"A Serpa Neto","year":"2012","unstructured":"Serpa Neto A, Cardoso SO, Manetta JA et al (2012) Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: a meta-analysis. JAMA 308:1651\u20131659. https:\/\/doi.org\/10.1001\/jama.2012.13730","journal-title":"JAMA"},{"key":"8562_CR8","doi-asserted-by":"publisher","first-page":"1872","DOI":"10.1001\/jama.2018.14280","volume":"320","author":"FD Simonis","year":"2018","unstructured":"Writing Group for the PReVENT Investigators, Simonis FD, Serpa Neto A et al (2018) Effect of a low vs intermediate tidal volume strategy on ventilator-free days in intensive care unit patients without ARDS: a randomized clinical trial. JAMA 320:1872\u20131880. https:\/\/doi.org\/10.1001\/jama.2018.14280","journal-title":"JAMA"},{"key":"8562_CR9","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/j.jcrc.2016.11.010","volume":"38","author":"E Tejerina","year":"2017","unstructured":"Tejerina E, Pelosi P, Muriel A et al (2017) Association between ventilatory settings and development of acute respiratory distress syndrome in mechanically ventilated patients due to brain injury. J Crit Care 38:341\u2013345. https:\/\/doi.org\/10.1016\/j.jcrc.2016.11.010","journal-title":"J Crit Care"},{"key":"8562_CR10","doi-asserted-by":"publisher","first-page":"964","DOI":"10.1164\/rccm.201610-2156SO","volume":"196","author":"P Radermacher","year":"2017","unstructured":"Radermacher P, Maggiore SM, Mercat A (2017) Fifty years of research in ARDS. Gas exchange in acute respiratory distress syndrome. Am J Respir Crit Care Med 196:964\u2013984. https:\/\/doi.org\/10.1164\/rccm.201610-2156SO","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR11","doi-asserted-by":"publisher","first-page":"2104","DOI":"10.1007\/s00134-025-08111-9","volume":"51","author":"IG Iavarone","year":"2025","unstructured":"Iavarone IG, Rocco PRM, Grieco DL et al (2025) Pathophysiology and clinical applications of PEEP in acute brain injury. Intensive Care Med 51:2104\u20132116. https:\/\/doi.org\/10.1007\/s00134-025-08111-9","journal-title":"Intensive Care Med"},{"key":"8562_CR12","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1164\/rccm.202402-0375OC","volume":"210","author":"L Mascia","year":"2024","unstructured":"Mascia L, Fanelli V, Mistretta A et al (2024) Lung-protective mechanical ventilation in patients with severe acute brain injury a multicenter randomized clinical trial (PROLABI). Am J Respir Crit Care Med 210:1123\u20131131. https:\/\/doi.org\/10.1164\/rccm.202402-0375OC","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR13","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-020-00969-5","author":"S Pitoni","year":"2020","unstructured":"Pitoni S, D\u2019Arrigo S, Grieco DL et al (2020) Tidal volume lowering by instrumental dead space reduction in brain-injured ARDS patients: effects on respiratory mechanics, gas exchange, and cerebral hemodynamics. Neurocrit Care L. https:\/\/doi.org\/10.1007\/s12028-020-00969-5","journal-title":"Neurocrit Care L"},{"key":"8562_CR14","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1007\/s00134-025-07808-1","volume":"51","author":"C Robba","year":"2025","unstructured":"Robba C, Giardiello D, Almondo C et al (2025) Ventilation practices in acute brain injured patients and association with outcomes: the VENTIBRAIN multicenter observational study. Intensive Care Med 51:318\u2013331. https:\/\/doi.org\/10.1007\/s00134-025-07808-1","journal-title":"Intensive Care Med"},{"key":"8562_CR15","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1007\/s00134-026-08412-7","volume":"52","author":"S Taran","year":"2026","unstructured":"Taran S, Citerio G, Taccone FS et al (2026) Dynamic driving pressure in acute brain injury: interpreting signals across ventilation modes and oxygenation severity-author\u2019s reply. Intensive Care Med 52:843\u2013844. https:\/\/doi.org\/10.1007\/s00134-026-08412-7","journal-title":"Intensive Care Med"},{"key":"8562_CR16","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/MCC.0000000000000377","volume":"23","author":"DL Grieco","year":"2017","unstructured":"Grieco DL, Chen L, Dres M, Brochard L (2017) Should we use driving pressure to set tidal volume? Curr Opin Crit Care 23:38\u201344. https:\/\/doi.org\/10.1097\/MCC.0000000000000377","journal-title":"Curr Opin Crit Care"},{"key":"8562_CR17","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1056\/NEJMsa1410639","volume":"372","author":"MBP Amato","year":"2015","unstructured":"Amato MBP, Meade MO, Slutsky AS et al (2015) Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 372:747\u2013755. https:\/\/doi.org\/10.1056\/NEJMsa1410639","journal-title":"N Engl J Med"},{"key":"8562_CR18","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1164\/rccm.202009-3536OC","volume":"203","author":"EC Goligher","year":"2021","unstructured":"Goligher EC, Costa ELV, Yarnell CJ et al (2021) Effect of lowering Vt on mortality in acute respiratory distress syndrome varies with respiratory system elastance. Am J Respir Crit Care Med 203:1378\u20131385. https:\/\/doi.org\/10.1164\/rccm.202009-3536OC","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR19","doi-asserted-by":"publisher","first-page":"2526","DOI":"10.1001\/jama.2012.5669","volume":"307","author":"VM Ranieri","year":"2012","unstructured":"ARDS Definition Task Force, Ranieri VM, Rubenfeld GD et al (2012) Acute respiratory distress syndrome: the Berlin definition. JAMA 307:2526\u20132533. https:\/\/doi.org\/10.1001\/jama.2012.5669","journal-title":"JAMA"},{"key":"8562_CR20","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1164\/rccm.202009-3467OC","volume":"204","author":"ELV Costa","year":"2021","unstructured":"Costa ELV, Slutsky AS, Brochard LJ et al (2021) Ventilatory variables and mechanical power in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 204:303\u2013311. https:\/\/doi.org\/10.1164\/rccm.202009-3467OC","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR21","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1007\/s00134-016-4505-2","volume":"42","author":"L Gattinoni","year":"2016","unstructured":"Gattinoni L, Tonetti T, Cressoni M et al (2016) Ventilator-related causes of lung injury: the mechanical power. Intensive Care Med 42:1567\u20131575. https:\/\/doi.org\/10.1007\/s00134-016-4505-2","journal-title":"Intensive Care Med"},{"key":"8562_CR22","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-026-05843-y","author":"DL Grieco","year":"2026","unstructured":"Grieco DL, Collino F, Steinberg I et al (2026) Lung recruitability determines the impact of PEEP on mechanical power in ARDS. Crit Care. https:\/\/doi.org\/10.1186\/s13054-026-05843-y","journal-title":"Crit Care"},{"key":"8562_CR23","doi-asserted-by":"publisher","first-page":"1831","DOI":"10.1164\/ajrccm.158.6.9801044","volume":"158","author":"L Brochard","year":"1998","unstructured":"Brochard L, Roudot-Thoraval F, Roupie E et al (1998) Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. The Multicenter Trail Group on Tidal Volume reduction in ARDS. Am J Respir Crit Care Med 158:1831\u20131838. https:\/\/doi.org\/10.1164\/ajrccm.158.6.9801044","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR24","doi-asserted-by":"publisher","first-page":"R1","DOI":"10.1186\/cc8230","volume":"14","author":"RM Determann","year":"2010","unstructured":"Determann RM, Royakkers A, Wolthuis EK et al (2010) Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial. Crit Care 14:R1. https:\/\/doi.org\/10.1186\/cc8230","journal-title":"Crit Care"},{"key":"8562_CR25","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.1097\/00003246-199908000-00015","volume":"27","author":"RG Brower","year":"1999","unstructured":"Brower RG, Shanholtz CB, Fessler HE et al (1999) Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients. Crit Care Med 27:1492\u20131498. https:\/\/doi.org\/10.1097\/00003246-199908000-00015","journal-title":"Crit Care Med"},{"key":"8562_CR26","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1056\/NEJM199802053380603","volume":"338","author":"TE Stewart","year":"1998","unstructured":"Stewart TE, Meade MO, Cook DJ et al (1998) Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. Pressure- and Volume-Limited Ventilation Strategy Group. N Engl J Med 338:355\u2013361. https:\/\/doi.org\/10.1056\/NEJM199802053380603","journal-title":"N Engl J Med"},{"key":"8562_CR27","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1007\/s00134-023-07050-7","volume":"49","author":"G Grasselli","year":"2023","unstructured":"Grasselli G, Calfee CS, Camporota L et al (2023) European Society of Intensive Care Medicine Guidelines on Acute Respiratory Distress Syndrome: definition, phenotyping and respiratory support strategies. Intensive Care Med 49:727\u2013759. https:\/\/doi.org\/10.1007\/s00134-023-07050-7","journal-title":"Intensive Care Med"},{"key":"8562_CR28","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1056\/NEJM199802053380602","volume":"338","author":"MB Amato","year":"1998","unstructured":"Amato MB, Barbas CS, Medeiros DM et al (1998) Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338:347\u2013354. https:\/\/doi.org\/10.1056\/NEJM199802053380602","journal-title":"N Engl J Med"},{"key":"8562_CR29","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.chest.2017.10.004","volume":"153","author":"MFS Schmidt","year":"2018","unstructured":"Schmidt MFS, Amaral ACKB, Fan E, Rubenfeld GD (2018) Driving pressure and hospital mortality in patients without ARDS: a cohort study. Chest 153:46\u201354. https:\/\/doi.org\/10.1016\/j.chest.2017.10.004","journal-title":"Chest"},{"key":"8562_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13054-019-2698-9","volume":"23","author":"MJ Lanspa","year":"2019","unstructured":"Lanspa MJ, Peltan ID, Jacobs JR et al (2019) Driving pressure is not associated with mortality in mechanically ventilated patients without ARDS. Crit Care 23:1\u20138. https:\/\/doi.org\/10.1186\/s13054-019-2698-9","journal-title":"Crit Care"},{"key":"8562_CR31","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1164\/ajrccm\/136.3.730","volume":"136","author":"L Gattinoni","year":"1987","unstructured":"Gattinoni L, Pesenti A, Avalli L et al (1987) Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study. Am Rev Respir Dis 136:730\u2013736. https:\/\/doi.org\/10.1164\/ajrccm\/136.3.730","journal-title":"Am Rev Respir Dis"},{"key":"8562_CR32","doi-asserted-by":"publisher","first-page":"776","DOI":"10.1007\/s00134-005-2627-z","volume":"31","author":"L Gattinoni","year":"2005","unstructured":"Gattinoni L, Pesenti A (2005) The concept of \u201cbaby lung.\u201d Intensive Care Med 31:776\u2013784. https:\/\/doi.org\/10.1007\/s00134-005-2627-z","journal-title":"Intensive Care Med"},{"key":"8562_CR33","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1016\/j.bja.2018.03.022","volume":"121","author":"DL Grieco","year":"2018","unstructured":"Grieco DL, Russo A, Roman\u00f2 B et al (2018) Lung volumes, respiratory mechanics and dynamic strain during general anaesthesia. Br J Anaesth 121:1156\u20131165. https:\/\/doi.org\/10.1016\/j.bja.2018.03.022","journal-title":"Br J Anaesth"},{"key":"8562_CR34","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1164\/rccm.200710-1589OC","volume":"178","author":"D Chiumello","year":"2008","unstructured":"Chiumello D, Carlesso E, Cadringher P et al (2008) Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome. Am J Respir Crit Care Med 178:346\u2013355. https:\/\/doi.org\/10.1164\/rccm.200710-1589OC","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR35","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1164\/ajrccm.161.2.9811008","volume":"161","author":"JR Hotchkiss","year":"2000","unstructured":"Hotchkiss JR, Blanch L, Murias G et al (2000) Effects of decreased respiratory frequency on ventilator-induced lung injury. Am J Respir Crit Care Med 161:463\u2013468. https:\/\/doi.org\/10.1164\/ajrccm.161.2.9811008","journal-title":"Am J Respir Crit Care Med"},{"key":"8562_CR36","doi-asserted-by":"publisher","first-page":"e838","DOI":"10.1097\/CCM.0000000000001718","volume":"44","author":"A Protti","year":"2016","unstructured":"Protti A, Maraffi T, Milesi M et al (2016) Role of strain rate in the pathogenesis of ventilator-induced lung edema. Crit Care Med 44:e838\u2013e845. https:\/\/doi.org\/10.1097\/CCM.0000000000001718","journal-title":"Crit Care Med"},{"key":"8562_CR37","doi-asserted-by":"publisher","first-page":"1783","DOI":"10.1007\/s00134-019-05805-9","volume":"45","author":"GWJ Hawryluk","year":"2019","unstructured":"Hawryluk GWJ, Aguilera S, Buki A et al (2019) A management algorithm for patients with intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC). Intensive Care Med 45:1783\u20131794. https:\/\/doi.org\/10.1007\/s00134-019-05805-9","journal-title":"Intensive Care Med"},{"key":"8562_CR38","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1186\/s40635-024-00697-6","volume":"12","author":"M Galizia","year":"2024","unstructured":"Galizia M, Ghidoni V, Catozzi G et al (2024) Predictors of VILI risk: driving pressure, 4DPRR and mechanical power ratio\u2014an experimental study. Intensive Care Med Exp 12:116. https:\/\/doi.org\/10.1186\/s40635-024-00697-6","journal-title":"Intensive Care Med Exp"},{"key":"8562_CR39","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1007\/s00134-016-4571-5","volume":"42","author":"JG Laffey","year":"2016","unstructured":"Laffey JG, Bellani G, Pham T et al (2016) Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study. Intensive Care Med 42:1865\u20131876. https:\/\/doi.org\/10.1007\/s00134-016-4571-5","journal-title":"Intensive Care Med"},{"key":"8562_CR40","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1001\/jama.2016.0291","volume":"315","author":"G Bellani","year":"2016","unstructured":"Bellani G, Laffey JG, Pham T et al (2016) Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA 315:788\u2013800. https:\/\/doi.org\/10.1001\/jama.2016.0291","journal-title":"JAMA"},{"key":"8562_CR41","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1007\/s00134-020-06035-0","volume":"46","author":"G Bellani","year":"2020","unstructured":"Bellani G, Pham T, Laffey JG (2020) Missed or delayed diagnosis of ARDS: a common and serious problem. Intensive Care Med 46:1180\u20131183. https:\/\/doi.org\/10.1007\/s00134-020-06035-0","journal-title":"Intensive Care Med"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-026-08562-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00134-026-08562-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00134-026-08562-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:22:48Z","timestamp":1790680968000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00134-026-08562-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["8562"],"URL":"https:\/\/doi.org\/10.1007\/s00134-026-08562-8","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,19]]},"assertion":[{"value":"9 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"DLG has received payments for travel expenses by Getinge, Draeger, and Hamilton, personal fees by Draeger, GE, Fisher and Paykel and Nihon Kohden, and research grants by Fisher and Paykel and GE. ER discloses payments for Travel expenses by Burke&Burke. Lecturing fees from Draeger and Seda. Consulting fees from PALL. MA has received payments for Board participation from Maquet, Air Liquide and Chiesi, and a research grant by GE. CR is a Section Editor for Intensive Care Medicine. She has not taken part in the review or selection process of this article.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Claude AI (Anthropic) was used for language editing and syntax revision. All authors retain full responsibility for the scientific content, interpretation, and conclusions of this work.","order":2,"name":"Ethics","label":"AI disclosure","group":{"name":"EthicsHeading","label":"Declarations"}}]}}