{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T13:13:59Z","timestamp":1778937239023,"version":"3.51.4"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[1997,11,1]],"date-time":"1997-11-01T00:00:00Z","timestamp":878342400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intensive Care Med"],"published-print":{"date-parts":[[1997,11]]},"DOI":"10.1007\/s001340050471","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T07:30:30Z","timestamp":1030260630000},"page":"1144-1149","source":"Crossref","is-referenced-by-count":128,"title":["Effects of early treatment with immunoglobulin on critical illness polyneuropathy following multiple organ failure and gram-negative sepsis"],"prefix":"10.1007","volume":"23","author":[{"given":"M.","family":"Mohr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Englisch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Roth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Burchardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Zielmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"70231144134_CR1","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1136\/jnnp.47.11.1223","volume":"47","author":"CF Bolton","year":"1984","unstructured":"Bolton CF, Gilbert JJ, Hahn AF, Sibbald WJ (1984) Polyneuropathy in critically ill patients. J Neurol Neurosurg Psychiatry 47 1223\u20131231","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"70231144134_CR2","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/ana.410330115","volume":"33","author":"CF Bolton","year":"1993","unstructured":"Bolton CF, Young GB, Zochodne DW (1993) The neurological complications of sepsis. Ann Neurol 33: 94\u2013100","journal-title":"Ann Neurol"},{"key":"70231144134_CR3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0303-8467(94)90023-X","volume":"96","author":"FSS Leijten","year":"1994","unstructured":"Leijten FSS, De Weerd AW (1994) Critical illness polyneuropathy. A review of the literature, definition and pathophysiology. Clin Neurol Neurosurg 96: 10\u201319","journal-title":"Clin Neurol Neurosurg"},{"key":"70231144134_CR4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/BF01708802","volume":"19","author":"CF Bolton","year":"1993","unstructured":"Bolton CF (1993) Neuromuscular complications of sepsis. Intensive Care Med 19: 58\u201363","journal-title":"Intensive Care Med"},{"key":"70231144134_CR5","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1097\/00003246-199608000-00022","volume":"24","author":"CF Bolton","year":"1996","unstructured":"Bolton CF (1996) Sepsis and the systemic inflammatory response syndrome: Neuromuscular manifestations. Crit Care Med 24:1408\u20131416","journal-title":"Crit Care Med"},{"key":"70231144134_CR6","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0303-8467(85)90060-5","volume":"87","author":"AAW Coul Op de","year":"1985","unstructured":"Op de Coul AAW, Lambregts PCLA, Koeman J, Van Puyenbroek MJE, Ter Laak HL, Gabreels Festen AAWM (1985) Neuromuscular complications in patients given pavulon (pancuronium bromide) during artificial respiration. Clin Neurol Neurosurg 87:17\u201322","journal-title":"Clin Neurol Neurosurg"},{"key":"70231144134_CR7","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/brain\/110.4.819","volume":"110","author":"DW Zochodne","year":"1987","unstructured":"Zochodne DW, Bolton CF, Wells GA, Gilbert JJ, Hahn AF, Brown JD, Sibbald WA (1987) Critical illness polyneuropathy. A complication of sepsis and multiple organ failure. Brain 110: 819\u2013842","journal-title":"Brain"},{"key":"70231144134_CR8","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1378\/chest.99.1.176","volume":"99","author":"NJ Witt","year":"1991","unstructured":"Witt NJ, Zochodne DW, Bolton CF, Grand\u2019Maison F, Wells G, Young GB, Sibbald WJ (1991) Peripheral nerve function in sepsis and multiple organ failure. Chest 99:176\u2013184","journal-title":"Chest"},{"key":"70231144134_CR9","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF01724794","volume":"16","author":"JB Lopez Messa","year":"1990","unstructured":"Lopez Messa JB, Garcia A (1990) Acute polyneuropathy in critically ill patients. Intensive Care Med 16: 159\u2013162","journal-title":"Intensive Care Med"},{"key":"70231144134_CR10","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1001\/jama.1995.03530150045032","volume":"274","author":"FSS Leijten","year":"1995","unstructured":"Leijten FSS, Handrick-de Weerd JE, Poortvliet DCJ, De Weerd AW (1995) The role of polyneuropathy in motor convalescence after prolonged mechanical ventilation. JAMA 274:1221\u20131225","journal-title":"JAMA"},{"key":"70231144134_CR11","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1001\/archsurg.1985.01390340007001","volume":"120","author":"JA Goris","year":"1985","unstructured":"Goris JA, Te Boekhorst TPA, Nuytinck KS, Gimber\u00e8re JSF (1985) Multiple organ failure. Arch Surg 120:1109\u20131115","journal-title":"Arch Surg"},{"key":"70231144134_CR12","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1097\/00005373-197611000-00006","volume":"16","author":"SP Baker","year":"1976","unstructured":"Baker SP (1976) The injury severity score: An update. J Trauma 16: 882\u2013885","journal-title":"J Trauma"},{"key":"70231144134_CR13","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1378\/chest.101.6.1644","volume":"101","author":"RC Bone","year":"1992","unstructured":"Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RMH, Sibbald WJ (1992) ACCP\/SCCM consensus conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 101: 1644\u20131655","journal-title":"Chest"},{"key":"70231144134_CR14","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1136\/bmj.2.5920.656","volume":"2","author":"MAE Ramsay","year":"1974","unstructured":"Ramsay MAE, Savege TM, Simpson BRJ, Goodwin R (1974) Controlled sedation with alphaxalone-alphadalone. BMJ 2: 656\u2013659","journal-title":"BMJ"},{"key":"70231144134_CR15","first-page":"933","volume":"35","author":"W Stephan","year":"1985","unstructured":"Stephan W, Dichtelm\u00fcller H, Schedel I (1985) Properties and efficacy of a human immunoglobulin M preparation for intravenous administration. Drug Res 35: 933\u2013936","journal-title":"Drug Res"},{"key":"70231144134_CR16","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1136\/jnnp.49.5.563","volume":"49","author":"CF Bolton","year":"1986","unstructured":"Bolton CF, Laverty DA, Brown JD, Witt NJ, Hahn AF, Sibbald WJ (1986) Critical ill polyneuropathy: electrophysiological studies and differentiation from Guilain-Barr\u00e9 syndrome. J Neurol Neurosurg Psychiatry 49: 563\u2013573","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"70231144134_CR17","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1097\/00003246-198510000-00009","volume":"13","author":"WA Knaus","year":"1985","unstructured":"Knaus WA, Draper EA, Wagner DP, Zimmerman JE (1985) APACHE II: a severity of disease classification system. Crit Care Med 13: 818\u2013829","journal-title":"Crit Care Med"},{"issue":"Suppl3","key":"70231144134_CR18","doi-asserted-by":"crossref","first-page":"S182","DOI":"10.1007\/BF01709697","volume":"16","author":"LG Thijs","year":"1990","unstructured":"Thijs LG, Schneider AJ, Groeneveld ABJ (1990) The haemodynamics of septic shock. Intensive Care Med 16 [Suppl3]:S182-S186","journal-title":"Intensive Care Med"},{"key":"70231144134_CR19","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/00003246-198408000-00004","volume":"12","author":"H Ellman","year":"1984","unstructured":"Ellman H (1984) Capillary permeability in septic patients. Crit Care Med 12: 629\u2013633","journal-title":"Crit Care Med"},{"key":"70231144134_CR20","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1097\/00003246-199608000-00010","volume":"24","author":"EF Hund","year":"1996","unstructured":"Hund EF, Fogel W, Krieger D, DeGeorgia M, Hacke W (1996) Critical illness polyneuropathy: clinical findings and outcomes of a frequent cause of neuromuscular weaning failure. Crit Care Med 24:1328\u20131333","journal-title":"Crit Care Med"},{"key":"70231144134_CR21","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/0887-8994(90)90062-6","volume":"6","author":"G Benzing","year":"1990","unstructured":"Benzing G, Iannaccone ST, Bove KE, Keebler PJ, Shockley LL (1990) Prolonged myasthenic syndrome after one week of muscle relaxants. Pediatr Neurol 6:190\u2013196","journal-title":"Pediatr Neurol"},{"key":"70231144134_CR22","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1097\/00000542-199003000-00030","volume":"72","author":"V Segredo","year":"1990","unstructured":"Segredo V, Matthay MA, Sharma ML, Gruenke LD, Caldwell JE, Miller RD (1990) Prolonged neuromuscular blockade after long-term administration of vecuronium in two critically ill patients. Anesthesiology 72: 566\u2013570","journal-title":"Anesthesiology"},{"key":"70231144134_CR23","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1097\/00003246-199109000-00006","volume":"19","author":"JL Gooch","year":"1991","unstructured":"Gooch JL, Suchyta MR, Balbierz JM, Petajan JH, Clemmer TP (1991) Prolonged paralysis after treatment with neuromuscular junction blocking agents. Crit Care Med 19:1125\u20131131","journal-title":"Crit Care Med"},{"issue":"Supppl I","key":"70231144134_CR24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/cei.1996.104.s1.83","volume":"104","author":"K Werdan","year":"1996","unstructured":"Werdan K, Pilz G (1996) Supplemental immune globulins in sepsis: a critical appraisal. Clin Exp immunol 104 (Supppl I): 83\u201390","journal-title":"Clin Exp immunol"},{"issue":"Suppl I","key":"70231144134_CR25","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/cei.1996.104.s1.3","volume":"104","author":"L Mouthon","year":"1996","unstructured":"Mouthon L, Kaveri SV, Spalter SH, Lacroix-Desmazes S, Lefranc C, Desai R, Kazatchkine MD (1996) Mechanisms of action of intravenous immune globulin in immune-mediated diseases. Clin Exp Immunol 104 (Suppl I): 3\u20139","journal-title":"Clin Exp Immunol"},{"key":"70231144134_CR26","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/978-3-642-85036-3_36","volume-title":"Sepsis \u2014 Current perspectives in pathophysiology and therapy","author":"HG Kress","year":"1994","unstructured":"Kress HG (1994) What is certain in the treatment with immunoglobulins? In: K Reinhart, K Eyrich, C Sprung (eds) Sepsis \u2014 Current perspectives in pathophysiology and therapy. Springer, Berlin Heidelberg New York, pp 449\u2013463"},{"key":"70231144134_CR27","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1001\/archsurg.1991.01410260126018","volume":"126","author":"L Dominioni","year":"1991","unstructured":"Dominioni L, Diongini R, Zanello M, Chiaranda M, Dionigi R, Acquarolo A, Ballabio A, Sguotti C (1991) Effect of high-dose IgG on survival of surgical patients with sepsis scores of 20 or greater. Arch Surg 126: 236\u2013240","journal-title":"Arch Surg"},{"key":"70231144134_CR28","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1097\/00003246-199109000-00003","volume":"19","author":"I Schedel","year":"1991","unstructured":"Schedel I, Dreikhausen U, Nentwig B, Hoeckenschnieder M, Rauthman D, Balikciouglu S, Coldewey R, Deicher H (1991) Treatment of gram-negative septic shock with an immunoglobulin preparation: A prospective, randomized clinical trial. Crit Care Med 19:1104\u20131113","journal-title":"Crit Care Med"},{"key":"70231144134_CR29","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1378\/chest.105.1.76","volume":"105","author":"G Pilz","year":"1994","unstructured":"Pilz G, Kreuzer E, K\u00e4\u00e4b S, Appel R, Werdan K (1994) Early sepsis treatment with immunoglobulins after cardiac surgery in score-identified high-risk patients. Chest 105: 76\u201382","journal-title":"Chest"},{"key":"70231144134_CR30","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1378\/chest.111.2.419","volume":"111","author":"G Pilz","year":"1997","unstructured":"Pilz G, Appel R, Kreuzer E, Werdan K (1997) Comparison of early IgM-enriched immunoglobulin vs polyvalent IgG administration in score-identified postcardiac surgical patients at high risk for sepsis. Chest 111: 419\u2013426","journal-title":"Chest"},{"key":"70231144134_CR31","first-page":"1494","volume":"17","author":"EFM Wijdicks","year":"1994","unstructured":"Wijdicks EFM, Fulgham JR (1994) Failure of high dose intravenous immunoglobulins to alter the clinical course of critical illness polyneuropathy [letter]. Muscle Nerve 17:1494\u20131495","journal-title":"Muscle Nerve"}],"container-title":["Intensive Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s001340050471.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s001340050471\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s001340050471","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T11:18:21Z","timestamp":1620040701000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s001340050471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1997,11]]}},"alternative-id":["70231144134"],"URL":"https:\/\/doi.org\/10.1007\/s001340050471","relation":{},"ISSN":["0342-4642","1432-1238"],"issn-type":[{"value":"0342-4642","type":"print"},{"value":"1432-1238","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,11]]}}}